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Protein

Zinc finger protein klf1

Gene

klf1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Required for maintaining cell viability in nitrogen-deficient stationary phase (G0) cells.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri17 – 41C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri47 – 70C2H2-type 2PROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription by RNA polymerase II Source: PomBase
  • positive regulation of transcription by RNA polymerase II Source: PomBase
  • regulation of fungal-type cell wall organization Source: PomBase

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein klf1
Alternative name(s):
Krueppel-like zinc finger transcription factor 1
Gene namesi
Name:klf1
ORF Names:SPAC1039.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC1039.05c
PomBaseiSPAC1039.05c klf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

Pathology & Biotechi

Disruption phenotypei

Defective in supporting the G0 state, while normal under vegetative condition.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003108421 – 781Zinc finger protein klf1Add BLAST781

Proteomic databases

MaxQBiQ9US36
PaxDbiQ9US36
PRIDEiQ9US36

Expressioni

Inductioni

Abundant in nitrogen-deficient G0 cells and rapidly decreases its levels upon nitrogen replenishment.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi278181, 2 interactors
STRINGi4896.SPAC1039.05c.1

Structurei

3D structure databases

ProteinModelPortaliQ9US36
SMRiQ9US36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri17 – 41C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri47 – 70C2H2-type 2PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

InParanoidiQ9US36
OMAiRHEKRNI
OrthoDBiEOG092C0MY0
PhylomeDBiQ9US36

Family and domain databases

InterProiView protein in InterPro
IPR007219 Transcription_factor_dom_fun
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF04082 Fungal_trans, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 2 hits
SUPFAMiSSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q9US36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKAKKSRAY QEGDIRYKCD FQGCTKSFTR KEHARRHFRS HTNSKAFICP
60 70 80 90 100
HCSSSFTRSD VLNRHVNQKH VKQNDAGSQT HPKHDKTLIS SSDQELPFPS
110 120 130 140 150
YVEADVQDAA YTDLKSHIDQ PILPDQPIIS DNFNEGLQSA IAQTGNNYMF
160 170 180 190 200
TTSRRNNSIS GSITIPESDQ QINLQNKFLS TPSIKNNANK SLSPQDSISI
210 220 230 240 250
FGTSPFNAYQ QNTDNFVCWL FDNMEKDAPT ESVSNFTDGI NAKQLNLMPV
260 270 280 290 300
LDSPTIDFLS SHFRVDDKLV AKDLLSLSAY SSLIQVMNNN YQLSEEALQY
310 320 330 340 350
ITRSRVNLWI AHYWKDFHPR WPFLHRGTLK VDEAPVELLL AMITMGMHFV
360 370 380 390 400
GDAFAYSIAV SIHSTLRFSI YTHPDFKPPA SLWVYQALLI AEIFEKMTST
410 420 430 440 450
VEQHNLSQIF HGVTIESMQN GLSSKDTVTE KIPKNMTGTN IAQHKWHQWV
460 470 480 490 500
DREASKRIAF FSFVLDSQHV ILFGYRPLID ITSVGLPLLC DEALWNADSY
510 520 530 540 550
EAWTSLLNEN DPPHFFPVLK MFLTNEHLPP KLSPWNMMIV LHGLTTIGWI
560 570 580 590 600
LSRENLGIVE NIMQNNGTNL KNWRILLKAS YKFWLRTYRV FFLNNGTLPL
610 620 630 640 650
NHPYVRGCLA TYELAHISLH TNIVALQTYA KSIVSTSRRL YASTSRYVSA
660 670 680 690 700
WLASDDSEVS IKHAVDMVEA FLGGDMEYDV QNETGLHRPW CLYVSTLILW
710 720 730 740 750
AYGYVSDGRC EMLEPGNNDC KSQLNAYLMQ MRTGLSEKAK DHVYVRSKTL
760 770 780
PLLKCVIDVL CPARWGLLVD GVRILSKLVQ L
Length:781
Mass (Da):89,010
Last modified:May 1, 2000 - v1
Checksum:i73E56906F7E6F234
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB63541.1
PIRiT50055
RefSeqiNP_594996.1, NM_001020427.2

Genome annotation databases

EnsemblFungiiSPAC1039.05c.1; SPAC1039.05c.1:pep; SPAC1039.05c
GeneIDi2541685
KEGGispo:SPAC1039.05c

Entry informationi

Entry nameiKLF1_SCHPO
AccessioniPrimary (citable) accession number: Q9US36
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 1, 2000
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names

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