UniProtKB - Q9URZ5 (VPS1_SCHPO)
Protein
Vacuolar protein sorting-associated protein 1
Gene
vps1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 34 – 41 | GTPSequence analysis | 8 | |
Nucleotide bindingi | 153 – 157 | GTPSequence analysis | 5 | |
Nucleotide bindingi | 222 – 225 | GTPSequence analysis | 4 |
GO - Molecular functioni
- GTPase activity Source: GO_Central
- GTP binding Source: UniProtKB-KW
- membrane scission GTPase motor activity Source: PomBase
- microtubule binding Source: GO_Central
GO - Biological processi
- dynamin family protein polymerization involved in mitochondrial fission Source: GO_Central
- endocytosis Source: PomBase
- membrane fusion Source: GO_Central
- mitochondrial fission Source: GO_Central
- peroxisome fission Source: GO_Central
- peroxisome organization Source: PomBase
- vesicle scission Source: PomBase
Keywordsi
Molecular function | Motor protein |
Ligand | GTP-binding, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-SPO-169911, Regulation of Apoptosis R-SPO-437239, Recycling pathway of L1 R-SPO-75153, Apoptotic execution phase R-SPO-8856828, Clathrin-mediated endocytosis |
Names & Taxonomyi
Protein namesi | Recommended name: Vacuolar protein sorting-associated protein 1 |
Gene namesi | Name:vps1 ORF Names:SPAC767.01c, SPAC9G1.14c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPAC767.01c, vps1 |
VEuPathDBi | FungiDB:SPAC767.01c |
Subcellular locationi
Golgi apparatus
- Golgi apparatus Source: PomBase
Mitochondrion
- mitochondrial membrane Source: GO_Central
Peroxisome
- peroxisome Source: GO_Central
Other locations
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000206587 | 1 – 678 | Vacuolar protein sorting-associated protein 1Add BLAST | 678 |
Proteomic databases
MaxQBi | Q9URZ5 |
PaxDbi | Q9URZ5 |
PRIDEi | Q9URZ5 |
PTM databases
iPTMneti | Q9URZ5 |
Interactioni
GO - Molecular functioni
- microtubule binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 279175, 60 interactors |
STRINGi | 4896.SPAC767.01c.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 24 – 311 | Dynamin-type GPROSITE-ProRule annotationAdd BLAST | 288 | |
Domaini | 592 – 678 | GEDPROSITE-ProRule annotationAdd BLAST | 87 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 34 – 41 | G1 motifPROSITE-ProRule annotation | 8 | |
Regioni | 60 – 62 | G2 motifPROSITE-ProRule annotation | 3 | |
Regioni | 153 – 156 | G3 motifPROSITE-ProRule annotation | 4 | |
Regioni | 222 – 225 | G4 motifPROSITE-ProRule annotation | 4 | |
Regioni | 252 – 255 | G5 motifPROSITE-ProRule annotation | 4 |
Sequence similaritiesi
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.PROSITE-ProRule annotation
Phylogenomic databases
eggNOGi | KOG0446, Eukaryota |
HOGENOMi | CLU_008964_5_2_1 |
InParanoidi | Q9URZ5 |
OMAi | LKESEYT |
PhylomeDBi | Q9URZ5 |
Family and domain databases
CDDi | cd08771, DLP_1, 1 hit |
InterProi | View protein in InterPro IPR001401, Dynamin_GTPase IPR019762, Dynamin_GTPase_CS IPR022812, Dynamin_SF IPR000375, Dynamin_stalk IPR030381, G_DYNAMIN_dom IPR003130, GED IPR020850, GED_dom IPR027417, P-loop_NTPase |
PANTHERi | PTHR11566, PTHR11566, 1 hit |
Pfami | View protein in Pfam PF01031, Dynamin_M, 1 hit PF00350, Dynamin_N, 1 hit PF02212, GED, 1 hit |
PRINTSi | PR00195, DYNAMIN |
SMARTi | View protein in SMART SM00053, DYNc, 1 hit SM00302, GED, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00410, G_DYNAMIN_1, 1 hit PS51718, G_DYNAMIN_2, 1 hit PS51388, GED, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9URZ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDPSLIKVVN QLQEAFSTVG VQNLIDLPQI TVVRSQSSGK SSVLENIVGR
60 70 80 90 100
DFLPRGTGIV TRRPLVLQLI NRPSASGKNE ETTTDSDGKD QNNSSEWGEF
110 120 130 140 150
LHLPGQKFFE FEKIREEIVR ETEEKTGKNV GISSVPIYLR IYSPHVLTLT
160 170 180 190 200
LVDLPGLTKV PVGDQPRDIE KQIREMVLKY ISKNNAIILA VNAANTDLAN
210 220 230 240 250
SDGLKLAREV DPEGLRTIGV LTKVDLMDKG TDVVDILAGR VIPLRLGYVP
260 270 280 290 300
VINRGQKDIE GKKSIRIALE AERNFFETHP SYGSKAQYCG TPFLARKLNM
310 320 330 340 350
ILMHHIRNTL PEIKVRINAA LAKYQAELHS LGDTPVGDNS SIVLNLITDF
360 370 380 390 400
CNEYRTVVDG RSEELSATEL SGGARIAFVF HEIFSNGIQA IDPFDEVKDS
410 420 430 440 450
DIRTILYNSS GPSPSLFMGT AAFEVIVKQQ IKRLEDPSLK CVSLIYDELV
460 470 480 490 500
RILNQLLQRP IFKRYPLLKD EFYKVVIGFF RKCMQPTNTL VMDMVAMEGS
510 520 530 540 550
YINTVHPDFL SGHQAMAIVQ SQNSKPIPVD PKTGKALTNN PVPPVETSSS
560 570 580 590 600
SGQNFFGSFF GSKNKKRLAA MEPPPPVLRA STTLSDREKT DTEVIKLLIM
610 620 630 640 650
SYFNIVKRTL ADMVPKSISL KMIKYSKEHI QHELLEQLYK SQAFDKLLQE
660 670
SEVTVQRRKE CEQMVESLLQ ASEIVSNV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB11498.1 |
PIRi | T50256 |
RefSeqi | XP_001713062.1, XM_001713010.2 |
Genome annotation databases
EnsemblFungii | SPAC767.01c.1; SPAC767.01c.1:pep; SPAC767.01c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329670 Genomic DNA Translation: CAB11498.1 |
PIRi | T50256 |
RefSeqi | XP_001713062.1, XM_001713010.2 |
3D structure databases
SMRi | Q9URZ5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 279175, 60 interactors |
STRINGi | 4896.SPAC767.01c.1 |
PTM databases
iPTMneti | Q9URZ5 |
Proteomic databases
MaxQBi | Q9URZ5 |
PaxDbi | Q9URZ5 |
PRIDEi | Q9URZ5 |
Genome annotation databases
EnsemblFungii | SPAC767.01c.1; SPAC767.01c.1:pep; SPAC767.01c |
Organism-specific databases
PomBasei | SPAC767.01c, vps1 |
VEuPathDBi | FungiDB:SPAC767.01c |
Phylogenomic databases
eggNOGi | KOG0446, Eukaryota |
HOGENOMi | CLU_008964_5_2_1 |
InParanoidi | Q9URZ5 |
OMAi | LKESEYT |
PhylomeDBi | Q9URZ5 |
Enzyme and pathway databases
Reactomei | R-SPO-169911, Regulation of Apoptosis R-SPO-437239, Recycling pathway of L1 R-SPO-75153, Apoptotic execution phase R-SPO-8856828, Clathrin-mediated endocytosis |
Miscellaneous databases
PROi | PR:Q9URZ5 |
Family and domain databases
CDDi | cd08771, DLP_1, 1 hit |
InterProi | View protein in InterPro IPR001401, Dynamin_GTPase IPR019762, Dynamin_GTPase_CS IPR022812, Dynamin_SF IPR000375, Dynamin_stalk IPR030381, G_DYNAMIN_dom IPR003130, GED IPR020850, GED_dom IPR027417, P-loop_NTPase |
PANTHERi | PTHR11566, PTHR11566, 1 hit |
Pfami | View protein in Pfam PF01031, Dynamin_M, 1 hit PF00350, Dynamin_N, 1 hit PF02212, GED, 1 hit |
PRINTSi | PR00195, DYNAMIN |
SMARTi | View protein in SMART SM00053, DYNc, 1 hit SM00302, GED, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00410, G_DYNAMIN_1, 1 hit PS51718, G_DYNAMIN_2, 1 hit PS51388, GED, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | VPS1_SCHPO | |
Accessioni | Q9URZ5Primary (citable) accession number: Q9URZ5 Secondary accession number(s): O14309 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 6, 2002 |
Last sequence update: | December 6, 2002 | |
Last modified: | April 7, 2021 | |
This is version 130 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families