UniProtKB - Q9UPW6 (SATB2_HUMAN)
DNA-binding protein SATB2
SATB2
Functioni
Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
1 PublicationRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 350 – 437 | CUT 1PROSITE-ProRule annotationAdd BLAST | 88 | |
DNA bindingi | 473 – 560 | CUT 2PROSITE-ProRule annotationAdd BLAST | 88 | |
DNA bindingi | 615 – 674 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 60 |
GO - Molecular functioni
- chromatin binding Source: Ensembl
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: NTNU_SB
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
- histone deacetylase binding Source: ARUK-UCL
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: NTNU_SB
GO - Biological processi
- cartilage development Source: Ensembl
- cellular response to organic substance Source: Ensembl
- chromatin remodeling Source: GO_Central
- commitment of neuronal cell to specific neuron type in forebrain Source: Ensembl
- embryonic pattern specification Source: Ensembl
- embryonic skeletal system morphogenesis Source: Ensembl
- negative regulation of transcription by RNA polymerase II Source: Ensembl
- neuron migration Source: Ensembl
- osteoblast development Source: Ensembl
- positive regulation of transcription by RNA polymerase II Source: NTNU_SB
- regulation of transcription by RNA polymerase II Source: GO_Central
- roof of mouth development Source: Ensembl
Keywordsi
Molecular function | Chromatin regulator, Developmental protein, DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
PathwayCommonsi | Q9UPW6 |
Reactomei | R-HSA-4551638, SUMOylation of chromatin organization proteins R-HSA-8940973, RUNX2 regulates osteoblast differentiation |
SignaLinki | Q9UPW6 |
SIGNORi | Q9UPW6 |
Names & Taxonomyi
Protein namesi | Recommended name: DNA-binding protein SATB2Alternative name(s): Special AT-rich sequence-binding protein 2 |
Gene namesi | Name:SATB2 Synonyms:KIAA1034 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:21637, SATB2 |
MIMi | 608148, gene |
neXtProti | NX_Q9UPW6 |
VEuPathDBi | HostDB:ENSG00000119042 |
Subcellular locationi
Nucleus
- Nucleus matrix PROSITE-ProRule annotation1 Publication
Nucleus
- histone deacetylase complex Source: Ensembl
- nuclear matrix Source: UniProtKB-SubCell
- nucleoplasm Source: HPA
Other locations
- chromatin Source: NTNU_SB
- transcription regulator complex Source: Ensembl
Keywords - Cellular componenti
NucleusPathology & Biotechi
Involvement in diseasei
Cleft palate isolated (CPI)2 Publications
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 233 | K → R: Reduced sumoylation, impaired nuclear localization, but enhanced transcription factor activity. 1 Publication | 1 | |
Mutagenesisi | 350 | K → R: Reduced sumoylation, impaired nuclear localization, but enhanced transcription factor activity. 1 Publication | 1 |
Keywords - Diseasei
Disease variant, Mental retardationOrganism-specific databases
DisGeNETi | 23314 |
GeneReviewsi | SATB2 |
MalaCardsi | SATB2 |
MIMi | 119540, phenotype |
OpenTargetsi | ENSG00000119042 |
Orphaneti | 251019, 2q32q33 microdeletion syndrome 251028, SATB2-associated syndrome due to a chromosomal rearrangement 576283, SATB2-associated syndrome due to a pathogenic variant |
PharmGKBi | PA128394624 |
Miscellaneous databases
Pharosi | Q9UPW6, Tbio |
Genetic variation databases
BioMutai | SATB2 |
DMDMi | 13634020 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000202400 | 1 – 733 | DNA-binding protein SATB2Add BLAST | 733 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 20 | PhosphoserineCombined sources | 1 | |
Cross-linki | 24 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 30 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 39 | PhosphoserineCombined sources | 1 | |
Cross-linki | 161 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 233 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)Curated | ||
Cross-linki | 350 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO); alternateCurated | ||
Cross-linki | 350 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources | ||
Modified residuei | 454 | PhosphoserineCombined sources | 1 | |
Modified residuei | 467 | PhosphothreonineCombined sources | 1 | |
Cross-linki | 475 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 594 | PhosphoserineCombined sources | 1 | |
Cross-linki | 724 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources |
Post-translational modificationi
Keywords - PTMi
Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q9UPW6 |
jPOSTi | Q9UPW6 |
MassIVEi | Q9UPW6 |
MaxQBi | Q9UPW6 |
PaxDbi | Q9UPW6 |
PeptideAtlasi | Q9UPW6 |
PRIDEi | Q9UPW6 |
ProteomicsDBi | 61903 85463 [Q9UPW6-1] |
PTM databases
iPTMneti | Q9UPW6 |
PhosphoSitePlusi | Q9UPW6 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000119042, Expressed in neocortex and 198 other tissues |
ExpressionAtlasi | Q9UPW6, baseline and differential |
Genevisiblei | Q9UPW6, HS |
Organism-specific databases
HPAi | ENSG00000119042, Group enriched (brain, intestine) |
Interactioni
Subunit structurei
Interacts with ATF4 and RUNX2; resulting in enhanced DNA binding and transactivation by these transcription factors (By similarity).
Interacts with PIAS1.
By similarity1 PublicationBinary interactionsi
Q9UPW6
With | #Exp. | IntAct |
---|---|---|
POLR2J3 [Q9H1A7] | 3 | EBI-8298169,EBI-12818681 |
RAB3IL1 [Q8TBN0] | 3 | EBI-8298169,EBI-743796 |
TP63 - isoform 2 [Q9H3D4-2] | 5 | EBI-8298169,EBI-6481107 |
GO - Molecular functioni
- histone deacetylase binding Source: ARUK-UCL
Protein-protein interaction databases
BioGRIDi | 116905, 84 interactors |
DIPi | DIP-60551N |
ELMi | Q9UPW6 |
IntActi | Q9UPW6, 50 interactors |
MINTi | Q9UPW6 |
STRINGi | 9606.ENSP00000401112 |
Miscellaneous databases
RNActi | Q9UPW6, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q9UPW6 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q9UPW6 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 57 – 158 | ULDPROSITE-ProRule annotationAdd BLAST | 102 | |
Domaini | 161 – 234 | CUTLPROSITE-ProRule annotationAdd BLAST | 74 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 47 | DisorderedSequence analysisAdd BLAST | 47 | |
Regioni | 435 – 473 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 580 – 617 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 694 – 733 | DisorderedSequence analysisAdd BLAST | 40 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 19 | Basic and acidic residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 439 – 473 | Polar residuesSequence analysisAdd BLAST | 35 | |
Compositional biasi | 595 – 610 | Pro residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 694 – 712 | Acidic residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 713 – 733 | Basic and acidic residuesSequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Homeobox, RepeatPhylogenomic databases
eggNOGi | KOG3755, Eukaryota |
GeneTreei | ENSGT00390000008096 |
HOGENOMi | CLU_012559_1_0_1 |
InParanoidi | Q9UPW6 |
OMAi | YCDLPVG |
PhylomeDBi | Q9UPW6 |
TreeFami | TF332714 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit cd11585, SATB1_N, 1 hit |
Gene3Di | 1.10.260.40, 2 hits 1.10.260.70, 1 hit 3.10.20.710, 1 hit |
InterProi | View protein in InterPro IPR003350, CUT_dom IPR032355, CUTL IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR010982, Lambda_DNA-bd_dom_sf IPR039673, SATB1/SATB2 IPR038216, SATB_CUTL_sf IPR038224, SATB_ULD_sf IPR032392, ULD |
PANTHERi | PTHR15116, PTHR15116, 1 hit |
Pfami | View protein in Pfam PF02376, CUT, 2 hits PF16557, CUTL, 1 hit PF00046, Homeodomain, 1 hit PF16534, ULD, 1 hit |
SMARTi | View protein in SMART SM01109, CUT, 2 hits SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF47413, SSF47413, 2 hits |
PROSITEi | View protein in PROSITE PS51042, CUT, 2 hits PS51983, CUTL, 1 hit PS50071, HOMEOBOX_2, 1 hit PS51982, ULD, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MERRSESPCL RDSPDRRSGS PDVKGPPPVK VARLEQNGSP MGARGRPNGA
60 70 80 90 100
VAKAVGGLMI PVFCVVEQLD GSLEYDNREE HAEFVLVRKD VLFSQLVETA
110 120 130 140 150
LLALGYSHSS AAQAQGIIKL GRWNPLPLSY VTDAPDATVA DMLQDVYHVV
160 170 180 190 200
TLKIQLQSCS KLEDLPAEQW NHATVRNALK ELLKEMNQST LAKECPLSQS
210 220 230 240 250
MISSIVNSTY YANVSATKCQ EFGRWYKKYK KIKVERVERE NLSDYCVLGQ
260 270 280 290 300
RPMHLPNMNQ LASLGKTNEQ SPHSQIHHST PIRNQVPALQ PIMSPGLLSP
310 320 330 340 350
QLSPQLVRQQ IAMAHLINQQ IAVSRLLAHQ HPQAINQQFL NHPPIPRAVK
360 370 380 390 400
PEPTNSSVEV SPDIYQQVRD ELKRASVSQA VFARVAFNRT QGLLSEILRK
410 420 430 440 450
EEDPRTASQS LLVNLRAMQN FLNLPEVERD RIYQDERERS MNPNVSMVSS
460 470 480 490 500
ASSSPSSSRT PQAKTSTPTT DLPIKVDGAN INITAAIYDE IQQEMKRAKV
510 520 530 540 550
SQALFAKVAA NKSQGWLCEL LRWKENPSPE NRTLWENLCT IRRFLNLPQH
560 570 580 590 600
ERDVIYEEES RHHHSERMQH VVQLPPEPVQ VLHRQQSQPA KESSPPREEA
610 620 630 640 650
PPPPPPTEDS CAKKPRSRTK ISLEALGILQ SFIHDVGLYP DQEAIHTLSA
660 670 680 690 700
QLDLPKHTII KFFQNQRYHV KHHGKLKEHL GSAVDVAEYK DEELLTESEE
710 720 730
NDSEEGSEEM YKVEAEEENA DKSKAAPAEI DQR
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9JR56 | C9JR56_HUMAN | DNA-binding protein SATB | SATB2 | 674 | Annotation score: | ||
F8WCV6 | F8WCV6_HUMAN | DNA-binding protein SATB2 | SATB2 | 126 | Annotation score: |
Sequence cautioni
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_059320 | 263 | S → P. Corresponds to variant dbSNP:rs12619995Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_054416 | 116 – 233 | Missing in isoform 2. 1 PublicationAdd BLAST | 118 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB028957 mRNA Translation: BAA82986.1 Different initiation. AK291463 mRNA Translation: BAF84152.1 AC016746 Genomic DNA No translation available. AC017096 Genomic DNA No translation available. CH471063 Genomic DNA Translation: EAW70180.1 BC098136 mRNA Translation: AAH98136.1 BC099723 mRNA Translation: AAH99723.1 BC103492 mRNA Translation: AAI03493.1 BC103500 mRNA Translation: AAI03501.1 |
CCDSi | CCDS2327.1 [Q9UPW6-1] |
RefSeqi | NP_001165980.1, NM_001172509.1 [Q9UPW6-1] NP_001165988.1, NM_001172517.1 [Q9UPW6-1] NP_056080.1, NM_015265.3 [Q9UPW6-1] XP_006712435.1, XM_006712372.2 XP_011509142.1, XM_011510840.2 [Q9UPW6-1] |
Genome annotation databases
Ensembli | ENST00000260926; ENSP00000260926; ENSG00000119042 ENST00000417098; ENSP00000401112; ENSG00000119042 ENST00000428695; ENSP00000388581; ENSG00000119042 [Q9UPW6-2] ENST00000457245; ENSP00000405420; ENSG00000119042 ENST00000614512; ENSP00000483287; ENSG00000119042 [Q9UPW6-2] |
GeneIDi | 23314 |
KEGGi | hsa:23314 |
MANE-Selecti | ENST00000417098.6; ENSP00000401112.1; NM_001172509.2; NP_001165980.1 |
UCSCi | uc002uuy.2, human [Q9UPW6-1] |
Keywords - Coding sequence diversityi
Alternative splicing, Chromosomal rearrangementSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB028957 mRNA Translation: BAA82986.1 Different initiation. AK291463 mRNA Translation: BAF84152.1 AC016746 Genomic DNA No translation available. AC017096 Genomic DNA No translation available. CH471063 Genomic DNA Translation: EAW70180.1 BC098136 mRNA Translation: AAH98136.1 BC099723 mRNA Translation: AAH99723.1 BC103492 mRNA Translation: AAI03493.1 BC103500 mRNA Translation: AAI03501.1 |
CCDSi | CCDS2327.1 [Q9UPW6-1] |
RefSeqi | NP_001165980.1, NM_001172509.1 [Q9UPW6-1] NP_001165988.1, NM_001172517.1 [Q9UPW6-1] NP_056080.1, NM_015265.3 [Q9UPW6-1] XP_006712435.1, XM_006712372.2 XP_011509142.1, XM_011510840.2 [Q9UPW6-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1WI3 | NMR | - | A | 615-672 | [»] | |
1WIZ | NMR | - | A | 350-437 | [»] | |
2CSF | NMR | - | A | 473-560 | [»] | |
SMRi | Q9UPW6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 116905, 84 interactors |
DIPi | DIP-60551N |
ELMi | Q9UPW6 |
IntActi | Q9UPW6, 50 interactors |
MINTi | Q9UPW6 |
STRINGi | 9606.ENSP00000401112 |
PTM databases
iPTMneti | Q9UPW6 |
PhosphoSitePlusi | Q9UPW6 |
Genetic variation databases
BioMutai | SATB2 |
DMDMi | 13634020 |
Proteomic databases
EPDi | Q9UPW6 |
jPOSTi | Q9UPW6 |
MassIVEi | Q9UPW6 |
MaxQBi | Q9UPW6 |
PaxDbi | Q9UPW6 |
PeptideAtlasi | Q9UPW6 |
PRIDEi | Q9UPW6 |
ProteomicsDBi | 61903 85463 [Q9UPW6-1] |
Protocols and materials databases
Antibodypediai | 19915, 311 antibodies from 40 providers |
DNASUi | 23314 |
Genome annotation databases
Ensembli | ENST00000260926; ENSP00000260926; ENSG00000119042 ENST00000417098; ENSP00000401112; ENSG00000119042 ENST00000428695; ENSP00000388581; ENSG00000119042 [Q9UPW6-2] ENST00000457245; ENSP00000405420; ENSG00000119042 ENST00000614512; ENSP00000483287; ENSG00000119042 [Q9UPW6-2] |
GeneIDi | 23314 |
KEGGi | hsa:23314 |
MANE-Selecti | ENST00000417098.6; ENSP00000401112.1; NM_001172509.2; NP_001165980.1 |
UCSCi | uc002uuy.2, human [Q9UPW6-1] |
Organism-specific databases
CTDi | 23314 |
DisGeNETi | 23314 |
GeneCardsi | SATB2 |
GeneReviewsi | SATB2 |
HGNCi | HGNC:21637, SATB2 |
HPAi | ENSG00000119042, Group enriched (brain, intestine) |
MalaCardsi | SATB2 |
MIMi | 119540, phenotype 608148, gene |
neXtProti | NX_Q9UPW6 |
OpenTargetsi | ENSG00000119042 |
Orphaneti | 251019, 2q32q33 microdeletion syndrome 251028, SATB2-associated syndrome due to a chromosomal rearrangement 576283, SATB2-associated syndrome due to a pathogenic variant |
PharmGKBi | PA128394624 |
VEuPathDBi | HostDB:ENSG00000119042 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3755, Eukaryota |
GeneTreei | ENSGT00390000008096 |
HOGENOMi | CLU_012559_1_0_1 |
InParanoidi | Q9UPW6 |
OMAi | YCDLPVG |
PhylomeDBi | Q9UPW6 |
TreeFami | TF332714 |
Enzyme and pathway databases
PathwayCommonsi | Q9UPW6 |
Reactomei | R-HSA-4551638, SUMOylation of chromatin organization proteins R-HSA-8940973, RUNX2 regulates osteoblast differentiation |
SignaLinki | Q9UPW6 |
SIGNORi | Q9UPW6 |
Miscellaneous databases
BioGRID-ORCSi | 23314, 14 hits in 1070 CRISPR screens |
ChiTaRSi | SATB2, human |
EvolutionaryTracei | Q9UPW6 |
GeneWikii | SATB2 |
GenomeRNAii | 23314 |
Pharosi | Q9UPW6, Tbio |
PROi | PR:Q9UPW6 |
RNActi | Q9UPW6, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000119042, Expressed in neocortex and 198 other tissues |
ExpressionAtlasi | Q9UPW6, baseline and differential |
Genevisiblei | Q9UPW6, HS |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit cd11585, SATB1_N, 1 hit |
Gene3Di | 1.10.260.40, 2 hits 1.10.260.70, 1 hit 3.10.20.710, 1 hit |
InterProi | View protein in InterPro IPR003350, CUT_dom IPR032355, CUTL IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR010982, Lambda_DNA-bd_dom_sf IPR039673, SATB1/SATB2 IPR038216, SATB_CUTL_sf IPR038224, SATB_ULD_sf IPR032392, ULD |
PANTHERi | PTHR15116, PTHR15116, 1 hit |
Pfami | View protein in Pfam PF02376, CUT, 2 hits PF16557, CUTL, 1 hit PF00046, Homeodomain, 1 hit PF16534, ULD, 1 hit |
SMARTi | View protein in SMART SM01109, CUT, 2 hits SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF47413, SSF47413, 2 hits |
PROSITEi | View protein in PROSITE PS51042, CUT, 2 hits PS51983, CUTL, 1 hit PS50071, HOMEOBOX_2, 1 hit PS51982, ULD, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SATB2_HUMAN | |
Accessioni | Q9UPW6Primary (citable) accession number: Q9UPW6 Secondary accession number(s): A8K5Z8, Q3ZB87, Q4V763 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 27, 2001 |
Last sequence update: | April 27, 2001 | |
Last modified: | February 23, 2022 | |
This is version 193 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 2
Human chromosome 2: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families