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Entry version 159 (10 Apr 2019)
Sequence version 2 (18 May 2010)
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Protein

Forkhead box protein J3

Gene

FOXJ3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi77 – 168Fork-headPROSITE-ProRule annotationAdd BLAST92

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Forkhead box protein J3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FOXJ3
Synonyms:KIAA1041
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000198815.8

Human Gene Nomenclature Database

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HGNCi
HGNC:29178 FOXJ3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616035 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UPW0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
22887

Open Targets

More...
OpenTargetsi
ENSG00000198815

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134945417

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FOXJ3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296434510

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000918551 – 622Forkhead box protein J3Add BLAST622

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei223PhosphoserineCombined sources1
Modified residuei295PhosphoserineCombined sources1
Modified residuei489PhosphoserineCombined sources1
Modified residuei606PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UPW0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UPW0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UPW0

PeptideAtlas

More...
PeptideAtlasi
Q9UPW0

PRoteomics IDEntifications database

More...
PRIDEi
Q9UPW0

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85458
85459 [Q9UPW0-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UPW0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UPW0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198815 Expressed in 240 organ(s), highest expression level in epithelium of mammary gland

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9UPW0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UPW0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA067284

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
116553, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UPW0, 14 interactors

Molecular INTeraction database

More...
MINTi
Q9UPW0

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000361653

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UPW0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UPW0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2294 Eukaryota
COG5025 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160362

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231184

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG051648

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UPW0

KEGG Orthology (KO)

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KOi
K09403

Identification of Orthologs from Complete Genome Data

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OMAi
TTIAGHH

Database of Orthologous Groups

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OrthoDBi
1270467at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UPW0

TreeFam database of animal gene trees

More...
TreeFami
TF333250

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00059 FH, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001766 Fork_head_dom
IPR018122 TF_fork_head_CS_1
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00250 Forkhead, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00053 FORKHEAD

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00339 FH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785 SSF46785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00657 FORK_HEAD_1, 1 hit
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UPW0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGLYGQACPS VTSLRMTSEL ESSLTSMDWL PQLTMRAAIQ KSDATQNAHG
60 70 80 90 100
TGISKKNALL DPNTTLDQEE VQQHKDGKPP YSYASLITFA INSSPKKKMT
110 120 130 140 150
LSEIYQWICD NFPYYREAGS GWKNSIRHNL SLNKCFLKVP RSKDDPGKGS
160 170 180 190 200
YWAIDTNPKE DVLPTRPKKR ARSVERASTP YSIDSDSLGM ECIISGSASP
210 220 230 240 250
TLAINTVTNK VTLYNTDQDG SDSPRSSLNN SLSDQSLASV NLNSVGSVHS
260 270 280 290 300
YTPVTSHPES VSQSLTPQQQ PQYNLPERDK QLLFSEYNFE DLSASFRSLY
310 320 330 340 350
KSVFEQSLSQ QGLMNIPSES SQQSHTSCTY QHSPSSTVST HPHSNQSSLS
360 370 380 390 400
NSHGSGLNTT GSNSVAQVSL SHPQMHTQPS PHPPHRPHGL PQHPQRSPHP
410 420 430 440 450
APHPQQHSQL QSPHPQHPSP HQHIQHHPNH QHQTLTHQAP PPPQQVSCNS
460 470 480 490 500
GVSNDWYATL DMLKESCRIA SSVNWSDVDL SQFQGLMESM RQADLKNWSL
510 520 530 540 550
DQVQFADLCS SLNQFFTQTG LIHSQSNVQQ NVCHGAMHPT KPSQHIGTGN
560 570 580 590 600
LYIDSRQNLP PSVMPPPGYP HIPQALSTPG TTMAGHHRAM NQQHMMPSQA
610 620
FQMRRSLPPD DIQDDFDWDS IV
Length:622
Mass (Da):68,960
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2C53E63C76AF057B
GO
Isoform 2 (identifier: Q9UPW0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     177-210: Missing.

Show »
Length:588
Mass (Da):65,533
Checksum:i73DC52B528BC4CDC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JVP0C9JVP0_HUMAN
Forkhead box J3, isoform CRA_b
FOXJ3 hCG_21708
382Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C1Y6H7C1Y6_HUMAN
Forkhead box protein J3
FOXJ3
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6VXT0F6VXT0_HUMAN
Forkhead box protein J3
FOXJ3
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JXI1C9JXI1_HUMAN
Forkhead box protein J3
FOXJ3
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA82993 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti485G → GG in CAB75651 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_039104162V → A2 PublicationsCorresponds to variant dbSNP:rs343376Ensembl.1
Natural variantiVAR_039105377T → P2 PublicationsCorresponds to variant dbSNP:rs1139978Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_010367177 – 210Missing in isoform 2. 1 PublicationAdd BLAST34

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB028964 mRNA Translation: BAA82993.2 Different initiation.
AC096540 Genomic DNA No translation available.
AC114492 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07162.1
CH471059 Genomic DNA Translation: EAX07163.1
CH471059 Genomic DNA Translation: EAX07164.1
CH471059 Genomic DNA Translation: EAX07165.1
BC014182 mRNA Translation: AAH14182.1
BC151828 mRNA Translation: AAI51829.1
BC152441 mRNA Translation: AAI52442.1
AL157422 mRNA Translation: CAB75651.2

The Consensus CDS (CCDS) project

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CCDSi
CCDS30689.1 [Q9UPW0-1]
CCDS55594.1 [Q9UPW0-2]

Protein sequence database of the Protein Information Resource

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PIRi
T46900

NCBI Reference Sequences

More...
RefSeqi
NP_001185779.1, NM_001198850.1 [Q9UPW0-1]
NP_001185780.1, NM_001198851.1 [Q9UPW0-1]
NP_001185781.1, NM_001198852.1 [Q9UPW0-2]
NP_055762.3, NM_014947.4 [Q9UPW0-1]
XP_011539328.1, XM_011541026.2 [Q9UPW0-1]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.26023

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361346; ENSP00000354620; ENSG00000198815 [Q9UPW0-1]
ENST00000361776; ENSP00000354449; ENSG00000198815 [Q9UPW0-2]
ENST00000372572; ENSP00000361653; ENSG00000198815 [Q9UPW0-1]
ENST00000372573; ENSP00000361654; ENSG00000198815 [Q9UPW0-1]
ENST00000545068; ENSP00000439044; ENSG00000198815 [Q9UPW0-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
22887

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:22887

UCSC genome browser

More...
UCSCi
uc001che.3 human [Q9UPW0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB028964 mRNA Translation: BAA82993.2 Different initiation.
AC096540 Genomic DNA No translation available.
AC114492 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07162.1
CH471059 Genomic DNA Translation: EAX07163.1
CH471059 Genomic DNA Translation: EAX07164.1
CH471059 Genomic DNA Translation: EAX07165.1
BC014182 mRNA Translation: AAH14182.1
BC151828 mRNA Translation: AAI51829.1
BC152441 mRNA Translation: AAI52442.1
AL157422 mRNA Translation: CAB75651.2
CCDSiCCDS30689.1 [Q9UPW0-1]
CCDS55594.1 [Q9UPW0-2]
PIRiT46900
RefSeqiNP_001185779.1, NM_001198850.1 [Q9UPW0-1]
NP_001185780.1, NM_001198851.1 [Q9UPW0-1]
NP_001185781.1, NM_001198852.1 [Q9UPW0-2]
NP_055762.3, NM_014947.4 [Q9UPW0-1]
XP_011539328.1, XM_011541026.2 [Q9UPW0-1]
UniGeneiHs.26023

3D structure databases

ProteinModelPortaliQ9UPW0
SMRiQ9UPW0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116553, 18 interactors
IntActiQ9UPW0, 14 interactors
MINTiQ9UPW0
STRINGi9606.ENSP00000361653

PTM databases

iPTMnetiQ9UPW0
PhosphoSitePlusiQ9UPW0

Polymorphism and mutation databases

BioMutaiFOXJ3
DMDMi296434510

Proteomic databases

EPDiQ9UPW0
jPOSTiQ9UPW0
PaxDbiQ9UPW0
PeptideAtlasiQ9UPW0
PRIDEiQ9UPW0
ProteomicsDBi85458
85459 [Q9UPW0-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
22887
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361346; ENSP00000354620; ENSG00000198815 [Q9UPW0-1]
ENST00000361776; ENSP00000354449; ENSG00000198815 [Q9UPW0-2]
ENST00000372572; ENSP00000361653; ENSG00000198815 [Q9UPW0-1]
ENST00000372573; ENSP00000361654; ENSG00000198815 [Q9UPW0-1]
ENST00000545068; ENSP00000439044; ENSG00000198815 [Q9UPW0-1]
GeneIDi22887
KEGGihsa:22887
UCSCiuc001che.3 human [Q9UPW0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
22887
DisGeNETi22887
EuPathDBiHostDB:ENSG00000198815.8

GeneCards: human genes, protein and diseases

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GeneCardsi
FOXJ3
HGNCiHGNC:29178 FOXJ3
HPAiHPA067284
MIMi616035 gene
neXtProtiNX_Q9UPW0
OpenTargetsiENSG00000198815
PharmGKBiPA134945417

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2294 Eukaryota
COG5025 LUCA
GeneTreeiENSGT00940000160362
HOGENOMiHOG000231184
HOVERGENiHBG051648
InParanoidiQ9UPW0
KOiK09403
OMAiTTIAGHH
OrthoDBi1270467at2759
PhylomeDBiQ9UPW0
TreeFamiTF333250

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FOXJ3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
22887

Protein Ontology

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PROi
PR:Q9UPW0

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000198815 Expressed in 240 organ(s), highest expression level in epithelium of mammary gland
ExpressionAtlasiQ9UPW0 baseline and differential
GenevisibleiQ9UPW0 HS

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR018122 TF_fork_head_CS_1
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00657 FORK_HEAD_1, 1 hit
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFOXJ3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UPW0
Secondary accession number(s): A7MBL7
, A7MD18, D3DPW2, Q9NSS7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 18, 2010
Last modified: April 10, 2019
This is version 159 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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Main funding by: National Institutes of Health

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