Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 122 (08 May 2019)
Sequence version 3 (18 May 2010)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Zinc finger RNA-binding protein 2

Gene

ZFR2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger RNA-binding protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZFR2
Synonyms:KIAA1086
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29189 ZFR2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UPR6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
23217

Open Targets

More...
OpenTargetsi
ENSG00000105278

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162409746

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZFR2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296453074

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003089581 – 939Zinc finger RNA-binding protein 2Add BLAST939

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UPR6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UPR6

PeptideAtlas

More...
PeptideAtlasi
Q9UPR6

PRoteomics IDEntifications database

More...
PRIDEi
Q9UPR6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85428
85429 [Q9UPR6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UPR6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UPR6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000105278 Expressed in 118 organ(s), highest expression level in pituitary gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UPR6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UPR6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043275
HPA055678

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116824, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000262961

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UPR6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini570 – 935DZFPROSITE-ProRule annotationAdd BLAST366

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili516 – 549Sequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi187 – 265Pro-richAdd BLAST79

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3792 Eukaryota
ENOG410XPBY LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162148

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000232147

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UPR6

Identification of Orthologs from Complete Genome Data

More...
OMAi
CSQKPTR

Database of Orthologous Groups

More...
OrthoDBi
612611at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UPR6

TreeFam database of animal gene trees

More...
TreeFami
TF320194

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006561 DZF_dom
IPR003604 Matrin/U1-like-C_Znf_C2H2
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07528 DZF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00572 DZF, 1 hit
SM00355 ZnF_C2H2, 3 hits
SM00451 ZnF_U1, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51703 DZF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UPR6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MATSQYFDFA QGGGPQYSAQ PPTLPLPTVG ASYTAQPTPG MDPAVNPAFP
60 70 80 90 100
PAAPAGYGGY QPHSGQDFAY GSRPQEPVPT ATTMATYQDS YSYGQSAAAR
110 120 130 140 150
SYEDRPYFQS AALQSGRMTA ADSGQPGTQE ACGQPSPHGS HSHAQPPQQA
160 170 180 190 200
PIVESGQPAS TLSSGYTYPT ATGVQPESSA SIVTSYPPPS YNPTCTAYTA
210 220 230 240 250
PSYPNYDASV YSAASPFYPP AQPPPPPGPP QQLPPPPAPA GSGSSPRADS
260 270 280 290 300
KPPLPSKLPR PKAGPRQLQL HYCDICKISC AGPQTYREHL GGQKHRKKEA
310 320 330 340 350
AQKTGVQPNG SPRGVQAQLH CDLCAVSCTG ADAYAAHIRG SKHQKVFKLH
360 370 380 390 400
AKLGKPIPTL EPALATESPP GAEAKPTSPT GPSVCASSRP ALAKRPVASK
410 420 430 440 450
ALCEGPPEPQ AAGCRPQWGK PAQPKLEGPG APTQGGSKEA PAGCSDAQPV
460 470 480 490 500
GPEYVEEVFS DEGRVLRFHC KLCECSFNDL NAKDLHVRGR RHRLQYRKKV
510 520 530 540 550
NPDLPIATEP SSRARKVLEE RMRKQRHLAE ERLEQLRRWH AERRRLEEEP
560 570 580 590 600
PQDVPPHAPP DWAQPLLMGR PESPASAPLQ PGRRPASSDD RHVMCKHATI
610 620 630 640 650
YPTEQELLAV QRAVSHAERA LKLVSDTLAE EDRGRREEEG DKRSSVAPQT
660 670 680 690 700
RVLKGVMRVG ILAKGLLLRG DRNVRLALLC SEKPTHSLLR RIAQQLPRQL
710 720 730 740 750
QMVTEDEYEV SSDPEANIVI SSCEEPRMQV TISVTSPLMR EDPSTDPGVE
760 770 780 790 800
EPQADAGDVL SPKKCLESLA ALRHARWFQA RASGLQPCVI VIRVLRDLCR
810 820 830 840 850
RVPTWGALPA WAMELLVEKA VSSAAGPLGP GDAVRRVLEC VATGTLLTDG
860 870 880 890 900
PGLQDPCERD QTDALEPMTL QEREDVTASA QHALRMLAFR QTHKVLGMDL
910 920 930
LPPRHRLGAR FRKRQRGPGE GEEGAGEKKR GRRGGEGLV
Length:939
Mass (Da):101,330
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i94E63C2C1C13C845
GO
Isoform 2 (identifier: Q9UPR6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     19-70: AQPPTLPLPT...QPHSGQDFAY → PEVETTPPAL...ICSILWDPAW
     71-939: Missing.

Show »
Length:70
Mass (Da):7,235
Checksum:i3D115F3601E7AED2
GO
Isoform 3 (identifier: Q9UPR6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     346-366: VFKLHAKLGKPIPTLEPALAT → GLLSHRQQAADPSGGNQPNLN
     367-939: Missing.

Note: No experimental confirmation available.
Show »
Length:366
Mass (Da):38,122
Checksum:iB09C9C1D0E66D7EE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EPY6K7EPY6_HUMAN
Zinc finger RNA-binding protein 2
ZFR2
44Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQC0K7EQC0_HUMAN
Zinc finger RNA-binding protein 2
ZFR2
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EKD7K7EKD7_HUMAN
Zinc finger RNA-binding protein 2
ZFR2
44Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti181S → F in DA237746 (PubMed:10470851).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_036886164S → L. Corresponds to variant dbSNP:rs2240235Ensembl.1
Natural variantiVAR_036887183V → M1 PublicationCorresponds to variant dbSNP:rs2240234Ensembl.1
Natural variantiVAR_036888210V → L. Corresponds to variant dbSNP:rs2240233Ensembl.1
Natural variantiVAR_036889235P → L. Corresponds to variant dbSNP:rs2240232Ensembl.1
Natural variantiVAR_036890577A → T. Corresponds to variant dbSNP:rs2301843Ensembl.1
Natural variantiVAR_036891589D → N. Corresponds to variant dbSNP:rs2301839Ensembl.1
Natural variantiVAR_061730718I → M. Corresponds to variant dbSNP:rs45465594Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04063519 – 70AQPPT…QDFAY → PEVETTPPALASGLPCALPW TVGCSGSDAVTALCPSLRGL ACICSILWDPAW in isoform 2. 1 PublicationAdd BLAST52
Alternative sequenceiVSP_04063671 – 939Missing in isoform 2. 1 PublicationAdd BLAST869
Alternative sequenceiVSP_057301346 – 366VFKLH…PALAT → GLLSHRQQAADPSGGNQPNL N in isoform 3. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_057302367 – 939Missing in isoform 3. 1 PublicationAdd BLAST573

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK295037 mRNA Translation: BAG58091.1
DA237746 mRNA No translation available.
AC004598 Genomic DNA No translation available.
AC005777 Genomic DNA No translation available.
AC093078 Genomic DNA No translation available.
BC034005 mRNA No translation available.
AB029009 mRNA Translation: BAA83038.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45921.1 [Q9UPR6-1]
CCDS45922.1 [Q9UPR6-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001139112.1, NM_001145640.1 [Q9UPR6-2]
NP_055989.1, NM_015174.1 [Q9UPR6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000262961; ENSP00000262961; ENSG00000105278 [Q9UPR6-1]
ENST00000438164; ENSP00000388974; ENSG00000105278 [Q9UPR6-3]
ENST00000439086; ENSP00000388567; ENSG00000105278 [Q9UPR6-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23217

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23217

UCSC genome browser

More...
UCSCi
uc002lyw.3 human [Q9UPR6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295037 mRNA Translation: BAG58091.1
DA237746 mRNA No translation available.
AC004598 Genomic DNA No translation available.
AC005777 Genomic DNA No translation available.
AC093078 Genomic DNA No translation available.
BC034005 mRNA No translation available.
AB029009 mRNA Translation: BAA83038.1
CCDSiCCDS45921.1 [Q9UPR6-1]
CCDS45922.1 [Q9UPR6-2]
RefSeqiNP_001139112.1, NM_001145640.1 [Q9UPR6-2]
NP_055989.1, NM_015174.1 [Q9UPR6-1]

3D structure databases

SMRiQ9UPR6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi116824, 3 interactors
STRINGi9606.ENSP00000262961

PTM databases

iPTMnetiQ9UPR6
PhosphoSitePlusiQ9UPR6

Polymorphism and mutation databases

BioMutaiZFR2
DMDMi296453074

Proteomic databases

jPOSTiQ9UPR6
PaxDbiQ9UPR6
PeptideAtlasiQ9UPR6
PRIDEiQ9UPR6
ProteomicsDBi85428
85429 [Q9UPR6-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000262961; ENSP00000262961; ENSG00000105278 [Q9UPR6-1]
ENST00000438164; ENSP00000388974; ENSG00000105278 [Q9UPR6-3]
ENST00000439086; ENSP00000388567; ENSG00000105278 [Q9UPR6-2]
GeneIDi23217
KEGGihsa:23217
UCSCiuc002lyw.3 human [Q9UPR6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23217
DisGeNETi23217

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZFR2

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0202695
HGNCiHGNC:29189 ZFR2
HPAiHPA043275
HPA055678
neXtProtiNX_Q9UPR6
OpenTargetsiENSG00000105278
PharmGKBiPA162409746

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3792 Eukaryota
ENOG410XPBY LUCA
GeneTreeiENSGT00940000162148
HOGENOMiHOG000232147
InParanoidiQ9UPR6
OMAiCSQKPTR
OrthoDBi612611at2759
PhylomeDBiQ9UPR6
TreeFamiTF320194

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZFR2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
23217

Protein Ontology

More...
PROi
PR:Q9UPR6

Gene expression databases

BgeeiENSG00000105278 Expressed in 118 organ(s), highest expression level in pituitary gland
ExpressionAtlasiQ9UPR6 baseline and differential
GenevisibleiQ9UPR6 HS

Family and domain databases

InterProiView protein in InterPro
IPR006561 DZF_dom
IPR003604 Matrin/U1-like-C_Znf_C2H2
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF07528 DZF, 1 hit
SMARTiView protein in SMART
SM00572 DZF, 1 hit
SM00355 ZnF_C2H2, 3 hits
SM00451 ZnF_U1, 3 hits
SUPFAMiSSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS51703 DZF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZFR2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UPR6
Secondary accession number(s): B4DHD0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 18, 2010
Last modified: May 8, 2019
This is version 122 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again