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UniProtKB - Q9UPR6 (ZFR2_HUMAN)

Entry version 133 (07 Apr 2021)
Sequence version 3 (18 May 2010)
Previous versions | rss
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Protein

Zinc finger RNA-binding protein 2

Gene

ZFR2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9UPR6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger RNA-binding protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZFR2
Synonyms:KIAA1086
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:29189, ZFR2

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9UPR6

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000105278.10

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		23217

Open Targets

More...OpenTargetsi		ENSG00000105278

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162409746

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9UPR6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZFR2

Domain mapping of disease mutations (DMDM)

More...DMDMi		296453074

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003089581 – 939Zinc finger RNA-binding protein 2Add BLAST939

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9UPR6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9UPR6

PeptideAtlas

More...PeptideAtlasi		Q9UPR6

PRoteomics IDEntifications database

More...PRIDEi		Q9UPR6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		4210
85428 [Q9UPR6-1]
85429 [Q9UPR6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9UPR6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9UPR6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000105278, Expressed in pituitary gland and 137 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9UPR6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9UPR6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000105278, Tissue enhanced (brain, pituitary gland, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		116824, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000262961

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9UPR6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9UPR6

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini570 – 935DZFPROSITE-ProRule annotationAdd BLAST366

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili516 – 549Sequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi187 – 265Pro-richAdd BLAST79

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3792, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162148

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_012026_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9UPR6

Identification of Orthologs from Complete Genome Data

More...OMAi		MTATDSC

Database of Orthologous Groups

More...OrthoDBi		612611at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9UPR6

TreeFam database of animal gene trees

More...TreeFami		TF320194

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.460.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006561, DZF_dom
IPR003604, Matrin/U1-like-C_Znf_C2H2
IPR043519, NT_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF07528, DZF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00572, DZF, 1 hit
SM00355, ZnF_C2H2, 3 hits
SM00451, ZnF_U1, 3 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51703, DZF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UPR6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MATSQYFDFA QGGGPQYSAQ PPTLPLPTVG ASYTAQPTPG MDPAVNPAFP 
        60         70         80         90        100
PAAPAGYGGY QPHSGQDFAY GSRPQEPVPT ATTMATYQDS YSYGQSAAAR 
       110        120        130        140        150
SYEDRPYFQS AALQSGRMTA ADSGQPGTQE ACGQPSPHGS HSHAQPPQQA 
       160        170        180        190        200
PIVESGQPAS TLSSGYTYPT ATGVQPESSA SIVTSYPPPS YNPTCTAYTA 
       210        220        230        240        250
PSYPNYDASV YSAASPFYPP AQPPPPPGPP QQLPPPPAPA GSGSSPRADS 
       260        270        280        290        300
KPPLPSKLPR PKAGPRQLQL HYCDICKISC AGPQTYREHL GGQKHRKKEA 
       310        320        330        340        350
AQKTGVQPNG SPRGVQAQLH CDLCAVSCTG ADAYAAHIRG SKHQKVFKLH 
       360        370        380        390        400
AKLGKPIPTL EPALATESPP GAEAKPTSPT GPSVCASSRP ALAKRPVASK 
       410        420        430        440        450
ALCEGPPEPQ AAGCRPQWGK PAQPKLEGPG APTQGGSKEA PAGCSDAQPV 
       460        470        480        490        500
GPEYVEEVFS DEGRVLRFHC KLCECSFNDL NAKDLHVRGR RHRLQYRKKV 
       510        520        530        540        550
NPDLPIATEP SSRARKVLEE RMRKQRHLAE ERLEQLRRWH AERRRLEEEP 
       560        570        580        590        600
PQDVPPHAPP DWAQPLLMGR PESPASAPLQ PGRRPASSDD RHVMCKHATI 
       610        620        630        640        650
YPTEQELLAV QRAVSHAERA LKLVSDTLAE EDRGRREEEG DKRSSVAPQT 
       660        670        680        690        700
RVLKGVMRVG ILAKGLLLRG DRNVRLALLC SEKPTHSLLR RIAQQLPRQL 
       710        720        730        740        750
QMVTEDEYEV SSDPEANIVI SSCEEPRMQV TISVTSPLMR EDPSTDPGVE 
       760        770        780        790        800
EPQADAGDVL SPKKCLESLA ALRHARWFQA RASGLQPCVI VIRVLRDLCR 
       810        820        830        840        850
RVPTWGALPA WAMELLVEKA VSSAAGPLGP GDAVRRVLEC VATGTLLTDG 
       860        870        880        890        900
PGLQDPCERD QTDALEPMTL QEREDVTASA QHALRMLAFR QTHKVLGMDL 
       910        920        930 
LPPRHRLGAR FRKRQRGPGE GEEGAGEKKR GRRGGEGLV
Length:939
Mass (Da):101,330
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i94E63C2C1C13C845
GO
Isoform 2 (identifier: Q9UPR6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     19-70: AQPPTLPLPT...QPHSGQDFAY → PEVETTPPAL...ICSILWDPAW
     71-939: Missing.

Show »
Length:70
Mass (Da):7,235
Checksum:i3D115F3601E7AED2
GO
Isoform 3 (identifier: Q9UPR6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     346-366: VFKLHAKLGKPIPTLEPALAT → GLLSHRQQAADPSGGNQPNLN
     367-939: Missing.

Show »
Length:366
Mass (Da):38,122
Checksum:iB09C9C1D0E66D7EE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6I8PRF6A0A6I8PRF6_HUMAN
Zinc finger RNA-binding protein 2
ZFR2
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQC0K7EQC0_HUMAN
Zinc finger RNA-binding protein 2
ZFR2
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EPY6K7EPY6_HUMAN
Zinc finger RNA-binding protein 2
ZFR2
44Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EKD7K7EKD7_HUMAN
Zinc finger RNA-binding protein 2
ZFR2
44Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti181S → F in DA237746 (PubMed:10470851).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_036886164S → L. Corresponds to variant dbSNP:rs2240235Ensembl.1
Natural variantiVAR_036887183V → M1 PublicationCorresponds to variant dbSNP:rs2240234Ensembl.1
Natural variantiVAR_036888210V → L. Corresponds to variant dbSNP:rs2240233Ensembl.1
Natural variantiVAR_036889235P → L. Corresponds to variant dbSNP:rs2240232Ensembl.1
Natural variantiVAR_036890577A → T. Corresponds to variant dbSNP:rs2301843Ensembl.1
Natural variantiVAR_036891589D → N. Corresponds to variant dbSNP:rs2301839Ensembl.1
Natural variantiVAR_061730718I → M. Corresponds to variant dbSNP:rs45465594Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04063519 – 70AQPPT…QDFAY → PEVETTPPALASGLPCALPW TVGCSGSDAVTALCPSLRGL ACICSILWDPAW in isoform 2. 1 PublicationAdd BLAST52
Alternative sequenceiVSP_04063671 – 939Missing in isoform 2. 1 PublicationAdd BLAST869
Alternative sequenceiVSP_057301346 – 366VFKLH…PALAT → GLLSHRQQAADPSGGNQPNL N in isoform 3. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_057302367 – 939Missing in isoform 3. 1 PublicationAdd BLAST573

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK295037 mRNA Translation: BAG58091.1
DA237746 mRNA No translation available.
AC004598 Genomic DNA No translation available.
AC005777 Genomic DNA No translation available.
AC093078 Genomic DNA No translation available.
BC034005 mRNA No translation available.
AB029009 mRNA Translation: BAA83038.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS45921.1 [Q9UPR6-1]
CCDS45922.1 [Q9UPR6-2]

NCBI Reference Sequences

More...RefSeqi		NP_001139112.1, NM_001145640.1 [Q9UPR6-2]
NP_055989.1, NM_015174.1 [Q9UPR6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000262961; ENSP00000262961; ENSG00000105278 [Q9UPR6-1]
ENST00000438164; ENSP00000388974; ENSG00000105278 [Q9UPR6-3]
ENST00000439086; ENSP00000388567; ENSG00000105278 [Q9UPR6-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		23217

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:23217

UCSC genome browser

More...UCSCi		uc002lyw.3, human [Q9UPR6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295037 mRNA Translation: BAG58091.1
DA237746 mRNA No translation available.
AC004598 Genomic DNA No translation available.
AC005777 Genomic DNA No translation available.
AC093078 Genomic DNA No translation available.
BC034005 mRNA No translation available.
AB029009 mRNA Translation: BAA83038.1
CCDSiCCDS45921.1 [Q9UPR6-1]
CCDS45922.1 [Q9UPR6-2]
RefSeqiNP_001139112.1, NM_001145640.1 [Q9UPR6-2]
NP_055989.1, NM_015174.1 [Q9UPR6-1]

3D structure databases

SMRiQ9UPR6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi116824, 3 interactors
STRINGi9606.ENSP00000262961

PTM databases

iPTMnetiQ9UPR6
PhosphoSitePlusiQ9UPR6

Genetic variation databases

BioMutaiZFR2
DMDMi296453074

Proteomic databases

MassIVEiQ9UPR6
PaxDbiQ9UPR6
PeptideAtlasiQ9UPR6
PRIDEiQ9UPR6
ProteomicsDBi4210
85428 [Q9UPR6-1]
85429 [Q9UPR6-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		52596, 7 antibodies

Genome annotation databases

EnsembliENST00000262961; ENSP00000262961; ENSG00000105278 [Q9UPR6-1]
ENST00000438164; ENSP00000388974; ENSG00000105278 [Q9UPR6-3]
ENST00000439086; ENSP00000388567; ENSG00000105278 [Q9UPR6-2]
GeneIDi23217
KEGGihsa:23217
UCSCiuc002lyw.3, human [Q9UPR6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23217
DisGeNETi23217

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZFR2
HGNCiHGNC:29189, ZFR2
HPAiENSG00000105278, Tissue enhanced (brain, pituitary gland, testis)
neXtProtiNX_Q9UPR6
OpenTargetsiENSG00000105278
PharmGKBiPA162409746
VEuPathDBiHostDB:ENSG00000105278.10

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3792, Eukaryota
GeneTreeiENSGT00940000162148
HOGENOMiCLU_012026_1_0_1
InParanoidiQ9UPR6
OMAiMTATDSC
OrthoDBi612611at2759
PhylomeDBiQ9UPR6
TreeFamiTF320194

Enzyme and pathway databases

PathwayCommonsiQ9UPR6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		23217, 8 hits in 993 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZFR2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		23217
PharosiQ9UPR6, Tdark

Protein Ontology

More...PROi		PR:Q9UPR6
RNActiQ9UPR6, protein

Gene expression databases

BgeeiENSG00000105278, Expressed in pituitary gland and 137 other tissues
ExpressionAtlasiQ9UPR6, baseline and differential
GenevisibleiQ9UPR6, HS

Family and domain databases

Gene3Di3.30.460.10, 1 hit
InterProiView protein in InterPro
IPR006561, DZF_dom
IPR003604, Matrin/U1-like-C_Znf_C2H2
IPR043519, NT_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF07528, DZF, 1 hit
SMARTiView protein in SMART
SM00572, DZF, 1 hit
SM00355, ZnF_C2H2, 3 hits
SM00451, ZnF_U1, 3 hits
SUPFAMiSSF57667, SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS51703, DZF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZFR2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UPR6
Secondary accession number(s): B4DHD0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 18, 2010
Last modified: April 7, 2021
This is version 133 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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