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Entry version 113 (02 Dec 2020)
Sequence version 3 (16 Jan 2019)
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Protein

AP2-interacting clathrin-endocytosis protein

Gene

KIAA1107

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processEndocytosis

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9UPP5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
AP2-interacting clathrin-endocytosis protein1 Publication
Short name:
APache1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29192, KIAA1107

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617945, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UPP5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell junction, Cell projection, Cytoplasmic vesicle, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000189195

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671620

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UPP5, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KIAA1107

Domain mapping of disease mutations (DMDM)

More...
DMDMi
172045554

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003206771 – 1279AP2-interacting clathrin-endocytosis proteinAdd BLAST1279

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UPP5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UPP5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UPP5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UPP5

PeptideAtlas

More...
PeptideAtlasi
Q9UPP5

PRoteomics IDEntifications database

More...
PRIDEi
Q9UPP5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85400 [Q9UPP5-1]
85401 [Q9UPP5-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UPP5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UPP5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UPP5, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via N-terminus) with adaptor protein complex AP-2 subunits alpha (AP2A1) and beta (AP2B1).

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
116883, 29 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UPP5, 26 interactors

Molecular INTeraction database

More...
MINTi
Q9UPP5

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000359404

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9UPP5, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QUK4, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154382

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UPP5

Database of Orthologous Groups

More...
OrthoDBi
213120at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UPP5

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027907, DUF4596
IPR040121, KIAA1107

The PANTHER Classification System

More...
PANTHERi
PTHR22427:SF2, PTHR22427:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15363, DUF4596, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9UPP5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSTDDQQKIQ AAAFDKGDDR RLGKKPIFSS SQQRKQVSDS GDIKIKSWRG
60 70 80 90 100
NNKKECWSYL STNKKMKSDG LGASGHSSST NRNSINKTLK QDDVKEKDGT
110 120 130 140 150
KIASKITKEL KTGGKNVSGK PKTVTKSKTE NGDKARLENM SPRQVVERSA
160 170 180 190 200
TAAAAATGQK NLLNGKGVRN QEGQISGARP KVLTGNLNVQ AKAKPLKKAT
210 220 230 240 250
GKDSPCLSIA GPSSRSTDSS MEFSISTECL DEPKENGSTE EEKPSGHKLS
260 270 280 290 300
FCDSPGQMMK NSVDSVKNST VAIKSRPVSR VTNGTSNKKS IHEQDTNVNN
310 320 330 340 350
SVLKKVSGKG CSEPVPQAIL KKRGTSNGCT AAQQRTKSTP SNLTKTQGSQ
360 370 380 390 400
GESPNSVKSS VSSRQSDENV AKLDHNTTTE KQAPKRKMVK QVHTALPKVN
410 420 430 440 450
AKIVAMPKNL NQSKKGETLN NKDSKQKMPP GQVISKTQPS SQRPLKHETS
460 470 480 490 500
TVQKSMFHDV RDNNNKDSVS EQKPHKPLIN LASEISDAEA LQSSCRPDPQ
510 520 530 540 550
KPLNDQEKEK LALECQNISK LDKSLKHELE SKQICLDKSE TKFPNHKETD
560 570 580 590 600
DCDAANICCH SVGSDNVNSK FYSTTALKYM VSNPNENSLN SNPVCDLDST
610 620 630 640 650
SAGQIHLISD RENQVGRKDT NKQSSIKCVE DVSLCNPERT NGTLNSAQED
660 670 680 690 700
KKSKVPVEGL TIPSKLSDES AMDEDKHATA DSDVSSKCFS GQLSEKNSPK
710 720 730 740 750
NMETSESPES HETPETPFVG HWNLSTGVLH QRESPESDTG SATTSSDDIK
760 770 780 790 800
PRSEDYDAGG SQDDDGSNDR GISKCGTMLC HDFLGRSSSD TSTPEELKIY
810 820 830 840 850
DSNLRIEVKM KKQSNNDLFQ VNSTSDDEIP RKRPEIWSRS AIVHSREREN
860 870 880 890 900
IPRGSVQFAQ EIDQVSSSAD ETEDERSEAE NVAENFSISN PAPQQFQGII
910 920 930 940 950
NLAFEDATEN ECREFSATKK FKRSVLLSVD ECEELGSDEG EVHTPFQASV
960 970 980 990 1000
DSFSPSDVFD GISHEHHGRT CYSRFSRESE DNILECKQNK GNSVCKNEST
1010 1020 1030 1040 1050
VLDLSSIDSS RKNKQSVSAT EKKNTIDVLS SRSRQLLRED KKVNNGSNVE
1060 1070 1080 1090 1100
NDIQQRSKFL DSDVKSQERP CHLDLHQREP NSDIPKNSST KSLDSFRSQV
1110 1120 1130 1140 1150
LPQEGPVKES HSTTTEKANI ALSAGDIDDC DTLAQTRMYD HRPSKTLSPI
1160 1170 1180 1190 1200
YEMDVIEAFE QKVESETHVT DMDFEDDQHF AKQDWTLLKQ LLSEQDSNLD
1210 1220 1230 1240 1250
VTNSVPEDLS LAQYLINQTL LLARDSSKPQ GITHIDTLNR WSELTSPLDS
1260 1270
SASITMASFS SEDCSPQGEW TILELETQH
Length:1,279
Mass (Da):140,918
Last modified:January 16, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6AB67B898C487F64
GO
Isoform 2 (identifier: Q9UPP5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1126-1129: DIDD → NVQK
     1130-1279: Missing.

Show »
Length:1,129
Mass (Da):123,838
Checksum:i1AE64D38A7576A14
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC28132 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti886F → L in AAH37317 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060300292H → R. Corresponds to variant dbSNP:rs2128647Ensembl.1
Natural variantiVAR_060301312S → I. Corresponds to variant dbSNP:rs12084085Ensembl.1
Natural variantiVAR_060302392V → L. Corresponds to variant dbSNP:rs7552286Ensembl.1
Natural variantiVAR_060303472Q → R. Corresponds to variant dbSNP:rs11166332Ensembl.1
Natural variantiVAR_060304551D → G. Corresponds to variant dbSNP:rs7523466Ensembl.1
Natural variantiVAR_060305585N → Y. Corresponds to variant dbSNP:rs7523552Ensembl.1
Natural variantiVAR_060306696K → E. Corresponds to variant dbSNP:rs3738439Ensembl.1
Natural variantiVAR_060307815N → S. Corresponds to variant dbSNP:rs560389Ensembl.1
Natural variantiVAR_060308918T → N. Corresponds to variant dbSNP:rs565156Ensembl.1
Natural variantiVAR_060309953F → V. Corresponds to variant dbSNP:rs17578364Ensembl.1
Natural variantiVAR_0603101028V → I. Corresponds to variant dbSNP:rs566576Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0317371126 – 1129DIDD → NVQK in isoform 2. 1 Publication4
Alternative sequenceiVSP_0317381130 – 1279Missing in isoform 2. 1 PublicationAdd BLAST150

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC104836 Genomic DNA No translation available.
AF017090 mRNA Translation: AAC28132.1 Different initiation.
AB029030 mRNA Translation: BAA83059.1
BC037317 mRNA Translation: AAH37317.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44172.2 [Q9UPP5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_056052.3, NM_015237.3 [Q9UPP5-1]

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
284697

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:284697

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104836 Genomic DNA No translation available.
AF017090 mRNA Translation: AAC28132.1 Different initiation.
AB029030 mRNA Translation: BAA83059.1
BC037317 mRNA Translation: AAH37317.2
CCDSiCCDS44172.2 [Q9UPP5-1]
RefSeqiNP_056052.3, NM_015237.3 [Q9UPP5-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi116883, 29 interactors
IntActiQ9UPP5, 26 interactors
MINTiQ9UPP5
STRINGi9606.ENSP00000359404

PTM databases

iPTMnetiQ9UPP5
PhosphoSitePlusiQ9UPP5

Polymorphism and mutation databases

BioMutaiKIAA1107
DMDMi172045554

Proteomic databases

EPDiQ9UPP5
jPOSTiQ9UPP5
MassIVEiQ9UPP5
PaxDbiQ9UPP5
PeptideAtlasiQ9UPP5
PRIDEiQ9UPP5
ProteomicsDBi85400 [Q9UPP5-1]
85401 [Q9UPP5-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33636, 31 antibodies

Genome annotation databases

GeneIDi284697
KEGGihsa:284697

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
284697

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KIAA1107
HGNCiHGNC:29192, KIAA1107
MIMi617945, gene
neXtProtiNX_Q9UPP5
OpenTargetsiENSG00000189195
PharmGKBiPA142671620

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QUK4, Eukaryota
GeneTreeiENSGT00940000154382
InParanoidiQ9UPP5
OrthoDBi213120at2759
PhylomeDBiQ9UPP5

Enzyme and pathway databases

PathwayCommonsiQ9UPP5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
23285, 6 hits in 844 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
KIAA1107, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
23285
PharosiQ9UPP5, Tdark

Protein Ontology

More...
PROi
PR:Q9UPP5
RNActiQ9UPP5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

ExpressionAtlasiQ9UPP5, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027907, DUF4596
IPR040121, KIAA1107
PANTHERiPTHR22427:SF2, PTHR22427:SF2, 1 hit
PfamiView protein in Pfam
PF15363, DUF4596, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK1107_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UPP5
Secondary accession number(s): A0A1B0GWG1, O14767, Q8N3X7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 16, 2019
Last modified: December 2, 2020
This is version 113 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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