UniProtKB - Q9UPD0 (Q9UPD0_HUMAN)
Protein
Submitted name:
MLL
Gene
MLL
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- histone methyltransferase activity (H3-K4 specific) Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: MLLImported |
Gene namesi | Name:MLLImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- MLL1 complex Source: InterPro
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 108 | DisorderedSequence analysisAdd BLAST | 108 | |
Regioni | 132 – 253 | DisorderedSequence analysisAdd BLAST | 122 | |
Regioni | 301 – 352 | DisorderedSequence analysisAdd BLAST | 52 | |
Regioni | 442 – 479 | DisorderedSequence analysisAdd BLAST | 38 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 373 – 393 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 37 – 58 | Pro-richSequence analysisAdd BLAST | 22 | |
Compositional biasi | 81 – 103 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 184 – 203 | PolarSequence analysisAdd BLAST | 20 | |
Compositional biasi | 204 – 226 | PolyampholyteSequence analysisAdd BLAST | 23 | |
Compositional biasi | 236 – 253 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 325 – 351 | PolyampholyteSequence analysisAdd BLAST | 27 | |
Compositional biasi | 445 – 479 | PolarSequence analysisAdd BLAST | 35 |
Keywords - Domaini
Coiled coilSequence analysisFamily and domain databases
InterProi | View protein in InterPro IPR037927, KMT2A |
PANTHERi | PTHR45838:SF2, PTHR45838:SF2, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q9UPD0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAHSCRWRFP ARPGTTGGGG GGGRRGLGGA PRQRVPALLL PPGPPVGGGG
60 70 80 90 100
PGAPPSPPAV AAAAAAAGSS GAGVPGGAAA ASAASSSSAS SSSSSSSSAS
110 120 130 140 150
SGPALLRVGP GFDAALQVSA AIGTNLRRFR AVFGESGGGG GSGEDEQFLG
160 170 180 190 200
FGSDEEVRVR SPTRSPSVKT SPRKPRGRPR SGSDRNSAIL SDPSVFSPLN
210 220 230 240 250
KSETKSGDKI KKKDSKSIEK KRGRPPTFPG VKIKITHGKD ISELPKGNKE
260 270 280 290 300
DSLKKIKRTP SATFQQATKI KKLRAGKLSP LKSKFKTGKL QIGRKGVQIV
310 320 330 340 350
RRRGRPPSTE RIKTPSGLLI NSELEKPQKV RKDKEGTPPL TKEDKTVVRQ
360 370 380 390 400
SPRRIKPVRI IPSSKRTDAT IAKQLLQRAK KGAQKKIEKE AAQLQGRKVK
410 420 430 440 450
TQVKNIRQFI MPVVSAISSR IIKTPRRFIE DEDYDPPIKI ARLESTPNSR
460 470
FSAPSCGSSE KSSAASQHSS QMSSDSSRS
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 479 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF036405 Genomic DNA Translation: AAC95283.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF036405 Genomic DNA Translation: AAC95283.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q9UPD0 |
Miscellaneous databases
ChiTaRSi | KMT2A, human |
Family and domain databases
InterProi | View protein in InterPro IPR037927, KMT2A |
PANTHERi | PTHR45838:SF2, PTHR45838:SF2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9UPD0_HUMAN | |
Accessioni | Q9UPD0Primary (citable) accession number: Q9UPD0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | October 7, 2020 | |
This is version 81 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |