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Entry version 152 (13 Feb 2019)
Sequence version 1 (01 May 2000)
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Protein

Probable G-protein coupled receptor 132

Gene

GPR132

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton-sensing activity.3 Publications

Caution

Was originally thought to be a receptor for lysophosphatidylcholine (LPC) and sphingosylphosphorylcholine (SPC), However, this work has been retracted.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer
Biological processStress response

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-416476 G alpha (q) signalling events

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable G-protein coupled receptor 132
Alternative name(s):
G2 accumulation protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GPR132
Synonyms:G2A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000183484.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17482 GPR132

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606167 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UNW8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 45ExtracellularSequence analysisAdd BLAST45
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei46 – 68Helical; Name=1Sequence analysisAdd BLAST23
Topological domaini69 – 79CytoplasmicSequence analysisAdd BLAST11
Transmembranei80 – 102Helical; Name=2Sequence analysisAdd BLAST23
Topological domaini103 – 116ExtracellularSequence analysisAdd BLAST14
Transmembranei117 – 138Helical; Name=3Sequence analysisAdd BLAST22
Topological domaini139 – 158CytoplasmicSequence analysisAdd BLAST20
Transmembranei159 – 178Helical; Name=4Sequence analysisAdd BLAST20
Topological domaini179 – 197ExtracellularSequence analysisAdd BLAST19
Transmembranei198 – 220Helical; Name=5Sequence analysisAdd BLAST23
Topological domaini221 – 246CytoplasmicSequence analysisAdd BLAST26
Transmembranei247 – 269Helical; Name=6Sequence analysisAdd BLAST23
Topological domaini270 – 288ExtracellularSequence analysisAdd BLAST19
Transmembranei289 – 311Helical; Name=7Sequence analysisAdd BLAST23
Topological domaini312 – 380CytoplasmicSequence analysisAdd BLAST69

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi7K → A: No change in basal activity. 1 Publication1
Mutagenesisi31K → A: Decreased IP1 accumulation at any pH. 1 Publication1
Mutagenesisi42R → A: Decreased basal activity at alkaline pH and loss of proton-sensing activity at low pH. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
29933

Open Targets

More...
OpenTargetsi
ENSG00000183484

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134940832

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL3085618

IUPHAR/BPS Guide to PHARMACOLOGY

More...
GuidetoPHARMACOLOGYi
128

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GPR132

Domain mapping of disease mutations (DMDM)

More...
DMDMi
37537754

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000694611 – 380Probable G-protein coupled receptor 132Add BLAST380

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi35N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi115 ↔ 186PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UNW8

PeptideAtlas

More...
PeptideAtlasi
Q9UNW8

PRoteomics IDEntifications database

More...
PRIDEi
Q9UNW8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85336
85337 [Q9UNW8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UNW8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UNW8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By stress and DNA-damaging agents.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000183484 Expressed in 100 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UNW8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UNW8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA029694
HPA029695

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000328818

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UNW8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi151 – 157Poly-Arg7

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKDS Eukaryota
ENOG4111F3F LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154241

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000013146

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG104029

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UNW8

KEGG Orthology (KO)

More...
KOi
K08426

Identification of Orthologs from Complete Genome Data

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OMAi
CLTAWLT

Database of Orthologous Groups

More...
OrthoDBi
664798at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UNW8

TreeFam database of animal gene trees

More...
TreeFami
TF331803

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005388 G2A_lysphc_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00001 7tm_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01563 G2ARECEPTOR
PR00237 GPCRRHODOPSN

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UNW8-1) [UniParc]FASTAAdd to basket
Also known as: G2A-a

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MCPMLLKNGY NGNATPVTTT APWASLGLSA KTCNNVSFEE SRIVLVVVYS
60 70 80 90 100
AVCTLGVPAN CLTAWLALLQ VLQGNVLAVY LLCLALCELL YTGTLPLWVI
110 120 130 140 150
YIRNQHRWTL GLLACKVTAY IFFCNIYVSI LFLCCISCDR FVAVVYALES
160 170 180 190 200
RGRRRRRTAI LISACIFILV GIVHYPVFQT EDKETCFDML QMDSRIAGYY
210 220 230 240 250
YARFTVGFAI PLSIIAFTNH RIFRSIKQSM GLSAAQKAKV KHSAIAVVVI
260 270 280 290 300
FLVCFAPYHL VLLVKAAAFS YYRGDRNAMC GLEERLYTAS VVFLCLSTVN
310 320 330 340 350
GVADPIIYVL ATDHSRQEVS RIHKGWKEWS MKTDVTRLTH SRDTEELQSP
360 370 380
VALADHYTFS RPVHPPGSPC PAKRLIEESC
Length:380
Mass (Da):42,499
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6DE63D17275ECD74
GO
Isoform 2 (identifier: Q9UNW8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-188: Missing.

Show »
Length:192
Mass (Da):21,555
Checksum:i039E1BE113D7CB24
GO
Isoform 3 (identifier: Q9UNW8-3) [UniParc]FASTAAdd to basket
Also known as: G2A-b

The sequence of this isoform differs from the canonical sequence as follows:
     1-11: MCPMLLKNGYN → MP

Note: More abundant than isoform 1 in leukocytes by approximately 3-fold.
Show »
Length:371
Mass (Da):41,462
Checksum:i85CF16178275BD91
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VRH8F8VRH8_HUMAN
Probable G-protein-coupled receptor...
GPR132
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JL29A0A0G2JL29_HUMAN
Probable G-protein-coupled receptor...
GPR132
10Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0084041 – 188Missing in isoform 2. 2 PublicationsAdd BLAST188
Alternative sequenceiVSP_0545921 – 11MCPMLLKNGYN → MP in isoform 3. 2 PublicationsAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF083955 mRNA Translation: AAD47380.1
AB465599 mRNA Translation: BAG84609.1
AB465600 mRNA Translation: BAG84610.1
EU432121 mRNA Translation: ABY87920.1
BT007257 mRNA Translation: AAP35921.1
AK292142 mRNA Translation: BAF84831.1
AK303654 mRNA Translation: BAG64656.1
AL512356 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81898.1
BC004555 mRNA No translation available.
BC084546 mRNA Translation: AAH84546.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS61567.1 [Q9UNW8-3]
CCDS9997.1 [Q9UNW8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001265623.1, NM_001278694.1 [Q9UNW8-1]
NP_001265624.1, NM_001278695.1 [Q9UNW8-3]
NP_001265625.1, NM_001278696.1 [Q9UNW8-2]
NP_037477.1, NM_013345.3 [Q9UNW8-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.532504

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000329797; ENSP00000328818; ENSG00000183484 [Q9UNW8-1]
ENST00000392585; ENSP00000376364; ENSG00000183484 [Q9UNW8-3]
ENST00000539291; ENSP00000438094; ENSG00000183484 [Q9UNW8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
29933

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:29933

UCSC genome browser

More...
UCSCi
uc001yqd.5 human [Q9UNW8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF083955 mRNA Translation: AAD47380.1
AB465599 mRNA Translation: BAG84609.1
AB465600 mRNA Translation: BAG84610.1
EU432121 mRNA Translation: ABY87920.1
BT007257 mRNA Translation: AAP35921.1
AK292142 mRNA Translation: BAF84831.1
AK303654 mRNA Translation: BAG64656.1
AL512356 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81898.1
BC004555 mRNA No translation available.
BC084546 mRNA Translation: AAH84546.1
CCDSiCCDS61567.1 [Q9UNW8-3]
CCDS9997.1 [Q9UNW8-1]
RefSeqiNP_001265623.1, NM_001278694.1 [Q9UNW8-1]
NP_001265624.1, NM_001278695.1 [Q9UNW8-3]
NP_001265625.1, NM_001278696.1 [Q9UNW8-2]
NP_037477.1, NM_013345.3 [Q9UNW8-1]
UniGeneiHs.532504

3D structure databases

ProteinModelPortaliQ9UNW8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000328818

Chemistry databases

ChEMBLiCHEMBL3085618
GuidetoPHARMACOLOGYi128

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

iPTMnetiQ9UNW8
PhosphoSitePlusiQ9UNW8

Polymorphism and mutation databases

BioMutaiGPR132
DMDMi37537754

Proteomic databases

PaxDbiQ9UNW8
PeptideAtlasiQ9UNW8
PRIDEiQ9UNW8
ProteomicsDBi85336
85337 [Q9UNW8-2]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
29933
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000329797; ENSP00000328818; ENSG00000183484 [Q9UNW8-1]
ENST00000392585; ENSP00000376364; ENSG00000183484 [Q9UNW8-3]
ENST00000539291; ENSP00000438094; ENSG00000183484 [Q9UNW8-1]
GeneIDi29933
KEGGihsa:29933
UCSCiuc001yqd.5 human [Q9UNW8-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
29933
DisGeNETi29933
EuPathDBiHostDB:ENSG00000183484.11

GeneCards: human genes, protein and diseases

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GeneCardsi
GPR132
HGNCiHGNC:17482 GPR132
HPAiHPA029694
HPA029695
MIMi606167 gene
neXtProtiNX_Q9UNW8
OpenTargetsiENSG00000183484
PharmGKBiPA134940832

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IKDS Eukaryota
ENOG4111F3F LUCA
GeneTreeiENSGT00940000154241
HOGENOMiHOG000013146
HOVERGENiHBG104029
InParanoidiQ9UNW8
KOiK08426
OMAiCLTAWLT
OrthoDBi664798at2759
PhylomeDBiQ9UNW8
TreeFamiTF331803

Enzyme and pathway databases

ReactomeiR-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-416476 G alpha (q) signalling events

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
GPR132

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
29933

Protein Ontology

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PROi
PR:Q9UNW8

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000183484 Expressed in 100 organ(s), highest expression level in blood
ExpressionAtlasiQ9UNW8 baseline and differential
GenevisibleiQ9UNW8 HS

Family and domain databases

InterProiView protein in InterPro
IPR005388 G2A_lysphc_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR01563 G2ARECEPTOR
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGP132_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UNW8
Secondary accession number(s): A8K7X7, B4E144, Q9BSU2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2003
Last sequence update: May 1, 2000
Last modified: February 13, 2019
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
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