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Entry version 182 (16 Oct 2019)
Sequence version 1 (01 May 2000)
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Protein

Probable dimethyladenosine transferase

Gene

DIMT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (PubMed:25851604). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604).1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei37S-adenosyl-L-methionine; via carbonyl oxygenPROSITE-ProRule annotation1 Publication1
Binding sitei39S-adenosyl-L-methionine; via amide nitrogenPROSITE-ProRule annotation1 Publication1
Binding sitei64S-adenosyl-L-methionine; via carbonyl oxygenPROSITE-ProRule annotation1 Publication1
Binding sitei85S-adenosyl-L-methioninePROSITE-ProRule annotation1 Publication1
Binding sitei113S-adenosyl-L-methioninePROSITE-ProRule annotation1 Publication1
Binding sitei128S-adenosyl-L-methioninePROSITE-ProRule annotation1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6790901 rRNA modification in the nucleus and cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable dimethyladenosine transferase (EC:2.1.1.1831 Publication)
Alternative name(s):
DIM1 dimethyladenosine transferase 1 homolog
DIM1 dimethyladenosine transferase 1-like
Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase
Probable 18S rRNA dimethylase
Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DIMT1
Synonyms:DIMT1L
ORF Names:HUSSY-05
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30217 DIMT1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612499 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UNQ2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
27292

Open Targets

More...
OpenTargetsi
ENSG00000086189

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162383599

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UNQ2

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
DIMT1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
27151492

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001014651 – 313Probable dimethyladenosine transferaseAdd BLAST313

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UNQ2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UNQ2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UNQ2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UNQ2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UNQ2

PeptideAtlas

More...
PeptideAtlasi
Q9UNQ2

PRoteomics IDEntifications database

More...
PRIDEi
Q9UNQ2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85325

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
Q9UNQ2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UNQ2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UNQ2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000086189 Expressed in 231 organ(s), highest expression level in endometrium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UNQ2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UNQ2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042944

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
118116, 103 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UNQ2, 23 interactors

Molecular INTeraction database

More...
MINTi
Q9UNQ2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000199320

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1313
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UNQ2

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9UNQ2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0820 Eukaryota
COG0030 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183142

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000227963

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UNQ2

KEGG Orthology (KO)

More...
KOi
K14191

Identification of Orthologs from Complete Genome Data

More...
OMAi
YYIATRL

Database of Orthologous Groups

More...
OrthoDBi
963506at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UNQ2

TreeFam database of animal gene trees

More...
TreeFami
TF354255

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001737 KsgA/Erm
IPR020596 rRNA_Ade_Mease_Trfase_CS
IPR020598 rRNA_Ade_methylase_Trfase_N
IPR011530 rRNA_adenine_dimethylase
IPR029063 SAM-dependent_MTases

The PANTHER Classification System

More...
PANTHERi
PTHR11727 PTHR11727, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00398 RrnaAD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00650 rADc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53335 SSF53335, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00755 ksgA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01131 RRNA_A_DIMETH, 1 hit
PS51689 SAM_RNA_A_N6_MT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9UNQ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKVKSGAIG RRRGRQEQRR ELKSAGGLMF NTGIGQHILK NPLIINSIID
60 70 80 90 100
KAALRPTDVV LEVGPGTGNM TVKLLEKAKK VVACELDPRL VAELHKRVQG
110 120 130 140 150
TPVASKLQVL VGDVLKTDLP FFDTCVANLP YQISSPFVFK LLLHRPFFRC
160 170 180 190 200
AILMFQREFA LRLVAKPGDK LYCRLSINTQ LLARVDHLMK VGKNNFRPPP
210 220 230 240 250
KVESSVVRIE PKNPPPPINF QEWDGLVRIT FVRKNKTLSA AFKSSAVQQL
260 270 280 290 300
LEKNYRIHCS VHNIIIPEDF SIADKIQQIL TSTGFSDKRA RSMDIDDFIR
310
LLHGFNAEGI HFS
Length:313
Mass (Da):35,236
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i306B9D4A4F9494A6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DGB1A0A0C4DGB1_HUMAN
rRNA adenine N(6)-methyltransferase
DIMT1
275Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RCL3D6RCL3_HUMAN
rRNA adenine N(6)-methyltransferase
DIMT1
154Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C0G7A0A494C0G7_HUMAN
rRNA adenine N(6)-methyltransferase
DIMT1
317Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC72947 differs from that shown. Contaminating sequence. Sequence of unknown origin in the N-terminal part.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti157 – 158RE → EN in CAA08815 (PubMed:11124703).Curated2
Sequence conflicti265 – 275IIPEDFSIADK → VSAAVYPVKQI in AAH02841 (PubMed:15489334).CuratedAdd BLAST11
Sequence conflicti276 – 313Missing in AAH02841 (PubMed:15489334).CuratedAdd BLAST38

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF102147 mRNA Translation: AAC97955.1
BC002841 mRNA Translation: AAH02841.1
BC010874 mRNA Translation: AAH10874.1
AJ009761 mRNA Translation: CAA08815.1
AF091078 mRNA Translation: AAC72947.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3981.1

NCBI Reference Sequences

More...
RefSeqi
NP_001335005.1, NM_001348076.1
NP_055288.1, NM_014473.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000199320; ENSP00000199320; ENSG00000086189

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
27292

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:27292

UCSC genome browser

More...
UCSCi
uc003jta.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF102147 mRNA Translation: AAC97955.1
BC002841 mRNA Translation: AAH02841.1
BC010874 mRNA Translation: AAH10874.1
AJ009761 mRNA Translation: CAA08815.1
AF091078 mRNA Translation: AAC72947.1 Sequence problems.
CCDSiCCDS3981.1
RefSeqiNP_001335005.1, NM_001348076.1
NP_055288.1, NM_014473.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ZQ9X-ray1.90A/B31-313[»]
SMRiQ9UNQ2
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi118116, 103 interactors
IntActiQ9UNQ2, 23 interactors
MINTiQ9UNQ2
STRINGi9606.ENSP00000199320

PTM databases

iPTMnetiQ9UNQ2
PhosphoSitePlusiQ9UNQ2

Polymorphism and mutation databases

BioMutaiDIMT1
DMDMi27151492

2D gel databases

SWISS-2DPAGEiQ9UNQ2

Proteomic databases

EPDiQ9UNQ2
jPOSTiQ9UNQ2
MassIVEiQ9UNQ2
MaxQBiQ9UNQ2
PaxDbiQ9UNQ2
PeptideAtlasiQ9UNQ2
PRIDEiQ9UNQ2
ProteomicsDBi85325

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
27292

Genome annotation databases

EnsembliENST00000199320; ENSP00000199320; ENSG00000086189
GeneIDi27292
KEGGihsa:27292
UCSCiuc003jta.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27292
DisGeNETi27292

GeneCards: human genes, protein and diseases

More...
GeneCardsi
DIMT1
HGNCiHGNC:30217 DIMT1
HPAiHPA042944
MIMi612499 gene
neXtProtiNX_Q9UNQ2
OpenTargetsiENSG00000086189
PharmGKBiPA162383599

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0820 Eukaryota
COG0030 LUCA
GeneTreeiENSGT00950000183142
HOGENOMiHOG000227963
InParanoidiQ9UNQ2
KOiK14191
OMAiYYIATRL
OrthoDBi963506at2759
PhylomeDBiQ9UNQ2
TreeFamiTF354255

Enzyme and pathway databases

ReactomeiR-HSA-6790901 rRNA modification in the nucleus and cytosol

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
DIMT1 human
EvolutionaryTraceiQ9UNQ2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
27292
PharosiQ9UNQ2

Protein Ontology

More...
PROi
PR:Q9UNQ2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000086189 Expressed in 231 organ(s), highest expression level in endometrium
ExpressionAtlasiQ9UNQ2 baseline and differential
GenevisibleiQ9UNQ2 HS

Family and domain databases

InterProiView protein in InterPro
IPR001737 KsgA/Erm
IPR020596 rRNA_Ade_Mease_Trfase_CS
IPR020598 rRNA_Ade_methylase_Trfase_N
IPR011530 rRNA_adenine_dimethylase
IPR029063 SAM-dependent_MTases
PANTHERiPTHR11727 PTHR11727, 1 hit
PfamiView protein in Pfam
PF00398 RrnaAD, 1 hit
SMARTiView protein in SMART
SM00650 rADc, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00755 ksgA, 1 hit
PROSITEiView protein in PROSITE
PS01131 RRNA_A_DIMETH, 1 hit
PS51689 SAM_RNA_A_N6_MT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDIM1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UNQ2
Secondary accession number(s): O76025, Q9BU77, Q9UES1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 13, 2002
Last sequence update: May 1, 2000
Last modified: October 16, 2019
This is version 182 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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