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1 to 25 of 34  Show
  1. 1
    "Molecular cloning of human oligophrenin-1 like (OPHN1L) gene, complete CDS."
    Xia J.H., Tang X.X., Yu K.P., Pan Q., Dai H.P.
    Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Heart, Liver and Placenta.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q."
    Borkhardt A., Bojesen S., Haas O.A., Fuchs U., Bartelheimer D., Loncarevic I.F., Bohle R.M., Harbott J., Repp R., Jaeger U., Viehmann S., Henn T., Korth P., Scharr D., Lampert F.
    Proc. Natl. Acad. Sci. U.S.A. 97:9168-9173(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2), DISEASE, VARIANT JMML SER-417.
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Category: Sequences.
    Tissue: Placenta.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50454 other entries.

  5. 5
    "Genomic structure of the human GRAF gene."
    Bojesen S.E., Link C., Borkhardt A.
    Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 53-785.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Ishikawa K., Nagase T., Suyama M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 62-814 (ISOFORM 1).
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 99 other entries.

  7. 7
    "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 11670 other entries.

  8. 8
    "Solution structure of the SH3 domain of human oligophrenin-1-like protein (KIAA0621)."
    RIKEN structural genomics initiative (RSGI)
    Submitted (DEC-2003) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 754-814.
    Category: Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  9. 9
    "Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1."
    Richnau N., Aspenstroem P.
    J. Biol. Chem. 276:35060-35070(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-195189.

    This publication is cited by 3 and mapped to 89 other entries.

  10. 10
    "PKNbeta interacts with the SH3 domains of Graf and a novel Graf related protein, Graf2, which are GTPase activating proteins for Rho family."
    Shibata H., Oishi K., Yamagiwa A., Matsumoto M., Mukai H., Ono Y.
    J. Biochem. 130:23-31(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q9UNA1.

    This publication is mapped to 1 other entry.

  11. 11
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-195189.

    This publication is cited by 2 and mapped to 85 other entries.

  12. 12
    "Current knowledge of the large RhoGAP family of proteins."
    Tcherkezian J., Lamarche-Vane N.
    Biol. Cell 99:67-86(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-195189.

    This publication is mapped to 86 other entries.

  13. 13
    "Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF."
    Matsui C., Kaieda S., Ikegami T., Mimori-Kiyosue Y.
    J. Biol. Chem. 283:33006-33020(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q9UNA1.

    This publication is mapped to 9 other entries.

  14. 14
    Category: Structure.
    Annotation: Graf residues important for the structural integrity are critical for binding RhoA and for the catalytic activity of GAP but GTPase selectivity appears to be modulated by a more subtle interplay involving residues on the periphery of the main interface.Imported.
    Source: GeneRIF:23092.

    This publication is mapped to 15 other entries.

  15. 15
    "Aberrant methylation of GTPase regulator associated with the focal adhesion kinase (GRAF) promoter is an adverse prognostic factor in myelodysplastic syndrome."
    Qian J., Qian Z., Lin J., Yao D.M., Zhu Z.H., Chen Q., Xiao G.F., Li J.Y.
    Eur. J. Haematol. 85:174-176(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: abnormal GRAF methylation might be an adverse prognostic event in MDSImported.
    Source: GeneRIF:23092.

    This publication is mapped to 8 other entries.

  16. 16
    "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
    Rose J.E., Behm F.M., Drgon T., Johnson C., Uhl G.R.
    Mol. Med. 16:247-253(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)Imported.
    Source: GeneRIF:23092.

    This publication is mapped to 11756 other entries.

  17. 17
    "[Quantification of GRAF gene expression in patients with acute myeloid leukemia using EvaGreen real time quantitative PCR]."
    Qian Z., Lin J., Qian J., Yao D.M., Wang Y.L., Han L.X., Zhu Z.H., Xiao G.F.
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27:290-293(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: The GRAF gene was down-regulated in AML which might play a role in the leukemogenesis.Imported.
    Source: GeneRIF:23092.

    This publication is mapped to 8 other entries.

  18. 18
    "Decreased expression of GRAF1/OPHN-1-L in the X-linked alpha thalassemia mental retardation syndrome."
    Barresi V., Ragusa A., Fichera M., Musso N., Castiglia L., Rappazzo G., Travali S., Mattina T., Romano C., Cocchi G., Condorelli D.F.
    BMC Med Genomics 3:28-28(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: The analysis of the expression pattern of the GRAF1/OPHN-1-L gene in human tissues and organs revealed the predominant brain expression of a novel splicing isoform.Imported.
    Source: GeneRIF:23092.

    This publication is mapped to 7 other entries.

  19. 19
    "GTPase regulator associated with the focal adhesion kinase (GRAF) transcript was down-regulated in patients with myeloid malignancies."
    Qian Z., Qian J., Lin J., Yao D.M., Chen Q., Ji R.B., Li Y., Xiao G.F., Li J.Y.
    J. Exp. Clin. Cancer Res. 29:111-111(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Decreased level of GRAF transcript is associated with acute myeloid leukemia myelodysplastic syndrome and chronic myeloid leukemia.Imported.
    Source: GeneRIF:23092.

    This publication is mapped to 8 other entries.

  20. 20
    "Abnormal methylation of GRAF promoter Chinese patients with acute myeloid leukemia."
    Qian J., Qian Z., Lin J., Yao D.M., Chen Q., Li Y., Ji R.B., Yang J., Xiao G.F., Wang Y.L.
    Leuk. Res. 35:783-786(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Findings suggest that the hypermethylation of GRAF promoter might be one of early events in the development of AML.Imported.
    Source: GeneRIF:23092.

    This publication is mapped to 8 other entries.

  21. 21
    "Skeletal muscle differentiation and fusion are regulated by the BAR-containing Rho-GTPase-activating protein (Rho-GAP), GRAF1."
    Doherty J.T., Lenhart K.C., Cameron M.V., Mack C.P., Conlon F.L., Taylor J.M.
    J. Biol. Chem. 286:25903-25921(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: a GTPase-activating protein that regulates muscle maturation and to highlight the functional importance of BAR domains in myotube formationImported.
    Source: GeneRIF:23092.

    This publication is mapped to 8 other entries.

  22. 22
    "NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons."
    Yokoyama K., Tezuka T., Kotani M., Nakazawa T., Hoshina N., Shimoda Y., Kakuta S., Sudo K., Watanabe K., Iwakura Y., Yamamoto T.
    EMBO J. 30:4739-4754(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q9UNA1.

    This publication is cited by 7 and mapped to 103 other entries.

  23. 23
    "The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading."
    Doherty G.J., Ahlund M.K., Howes M.T., Moren B., Parton R.G., McMahon H.T., Lundmark R.
    Mol. Biol. Cell 22:4380-4389(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: proposed that GRAF1 remodels membrane microdomains at adhesion sites into endocytic carriers facilitating membrane turnover during cell morphological changesImported.
    Source: GeneRIF:23092.

    This publication is mapped to 8 other entries.

  24. 24
    Category: Interaction.
    Source: IntAct:Q9UNA1.

    This publication is mapped to 719 other entries.

  25. 25
    "ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding."
    Wang Q., Hui H., Guo Z., Zhang W., Hu Y., He T., Tai Y., Peng P., Wang L.
    RNA 19:1525-1536(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: ADAR1 regulates the expression of ARHGAP26 through A-to-I RNA editing by disrupting the binding of miR-30b-3p and miR-573 within the 3' UTR of ARHGAP26.Imported.
    Source: GeneRIF:23092.

    This publication is mapped to 16 other entries.

1 to 25 of 34  Show
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