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Entry version 148 (10 Apr 2019)
Sequence version 2 (28 Jul 2009)
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Protein

Sex comb on midleg-like protein 1

Gene

SCML1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. May be involved in spermatogenesis during sexual maturation (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sex comb on midleg-like protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCML1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000047634.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10580 SCML1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300227 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UN30

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000047634

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34998

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SCML1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
254763330

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000976271 – 329Sex comb on midleg-like protein 1Add BLAST329

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei138PhosphoserineCombined sources1
Modified residuei238PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UN30

PeptideAtlas

More...
PeptideAtlasi
Q9UN30

PRoteomics IDEntifications database

More...
PRIDEi
Q9UN30

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85240
85241 [Q9UN30-1]
85242 [Q9UN30-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UN30

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UN30

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous. Expressed in fetal and adult tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000047634 Expressed in 214 organ(s), highest expression level in secondary oocyte

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UN30 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UN30 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035270
HPA035271
HPA061397

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112227, 28 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UN30, 17 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000369380

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UN30

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UN30

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini258 – 325SAMPROSITE-ProRule annotationAdd BLAST68

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SCM family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3766 Eukaryota
ENOG410Y4AQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164589

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000036073

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG094812

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UN30

KEGG Orthology (KO)

More...
KOi
K11464

Identification of Orthologs from Complete Genome Data

More...
OMAi
YAYETKP

Database of Orthologous Groups

More...
OrthoDBi
298184at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UN30

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001660 SAM
IPR013761 SAM/pointed_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00536 SAM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00454 SAM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769 SSF47769, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50105 SAM_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 3 (identifier: Q9UN30-3) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMSNSSSEID VIKTRIPTYD EDDNTILYAY ETKPEFVNKE PNIVSDASCN
60 70 80 90 100
TEEQLKTVDD VLIHCQVIYD ALQNLDKKID VIRRKVSKIQ RFHARSLWTN
110 120 130 140 150
HKRYGYKKHS YRLVKKLKLQ KMKKNEVYET FSYPESYSPT LPVSRRENNS
160 170 180 190 200
PSNLPRPSFC MEEYQRAELE EDPILSRTPS PVHPSDFSEH NCQPYYASDG
210 220 230 240 250
ATYGSSSGLC LGNPRADSIH NTYSTDHASA APPSVTRSPV ENDGYIEEGS
260 270 280 290 300
ITKHPSTWSV EAVVLFLKQT DPLALCPLVD LFRSHEIDGK ALLLLTSDVL
310 320
LKHLGVKLGT AVKLCYYIDR LKQGKCFEN
Length:329
Mass (Da):37,447
Last modified:July 28, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7B9D3679509DE56E
GO
Isoform 1 (identifier: Q9UN30-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-121: Missing.

Show »
Length:208
Mass (Da):23,131
Checksum:i372BAB0770E2204B
GO
Isoform 2 (identifier: Q9UN30-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     12-39: IKTRIPTYDEDDNTILYAYETKPEFVNK → Q

Show »
Length:302
Mass (Da):34,216
Checksum:i3D0B96B0865ABF96
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5H966Q5H966_HUMAN
Sex comb on midleg-like protein 1
SCML1
147Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0378001 – 121Missing in isoform 1. 3 PublicationsAdd BLAST121
Alternative sequenceiVSP_03780112 – 39IKTRI…EFVNK → Q in isoform 2. 1 PublicationAdd BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF160728 mRNA Translation: AAD47635.1
EU370780 Genomic DNA Translation: ABY68575.1
AK313993 mRNA Translation: BAG36705.1
Z93242 Genomic DNA No translation available.
CH471074 Genomic DNA Translation: EAW98929.1
BC105028 mRNA Translation: AAI05029.1
BC026159 mRNA Translation: AAH26159.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14182.2 [Q9UN30-2]
CCDS35210.1 [Q9UN30-3]
CCDS35211.1 [Q9UN30-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001032624.1, NM_001037535.2 [Q9UN30-1]
NP_001032625.1, NM_001037536.2 [Q9UN30-1]
NP_001032629.1, NM_001037540.2 [Q9UN30-3]
NP_006737.2, NM_006746.5 [Q9UN30-2]
XP_006724571.1, XM_006724508.3 [Q9UN30-3]
XP_016885212.1, XM_017029723.1 [Q9UN30-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.109655
Hs.658510

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000380041; ENSP00000369380; ENSG00000047634 [Q9UN30-3]
ENST00000380043; ENSP00000369382; ENSG00000047634 [Q9UN30-2]
ENST00000380045; ENSP00000369384; ENSG00000047634 [Q9UN30-1]
ENST00000398080; ENSP00000381154; ENSG00000047634 [Q9UN30-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6322

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6322

UCSC genome browser

More...
UCSCi
uc004cyb.5 human [Q9UN30-3]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF160728 mRNA Translation: AAD47635.1
EU370780 Genomic DNA Translation: ABY68575.1
AK313993 mRNA Translation: BAG36705.1
Z93242 Genomic DNA No translation available.
CH471074 Genomic DNA Translation: EAW98929.1
BC105028 mRNA Translation: AAI05029.1
BC026159 mRNA Translation: AAH26159.2
CCDSiCCDS14182.2 [Q9UN30-2]
CCDS35210.1 [Q9UN30-3]
CCDS35211.1 [Q9UN30-1]
RefSeqiNP_001032624.1, NM_001037535.2 [Q9UN30-1]
NP_001032625.1, NM_001037536.2 [Q9UN30-1]
NP_001032629.1, NM_001037540.2 [Q9UN30-3]
NP_006737.2, NM_006746.5 [Q9UN30-2]
XP_006724571.1, XM_006724508.3 [Q9UN30-3]
XP_016885212.1, XM_017029723.1 [Q9UN30-2]
UniGeneiHs.109655
Hs.658510

3D structure databases

ProteinModelPortaliQ9UN30
SMRiQ9UN30
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112227, 28 interactors
IntActiQ9UN30, 17 interactors
STRINGi9606.ENSP00000369380

PTM databases

iPTMnetiQ9UN30
PhosphoSitePlusiQ9UN30

Polymorphism and mutation databases

BioMutaiSCML1
DMDMi254763330

Proteomic databases

PaxDbiQ9UN30
PeptideAtlasiQ9UN30
PRIDEiQ9UN30
ProteomicsDBi85240
85241 [Q9UN30-1]
85242 [Q9UN30-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6322
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000380041; ENSP00000369380; ENSG00000047634 [Q9UN30-3]
ENST00000380043; ENSP00000369382; ENSG00000047634 [Q9UN30-2]
ENST00000380045; ENSP00000369384; ENSG00000047634 [Q9UN30-1]
ENST00000398080; ENSP00000381154; ENSG00000047634 [Q9UN30-1]
GeneIDi6322
KEGGihsa:6322
UCSCiuc004cyb.5 human [Q9UN30-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6322
EuPathDBiHostDB:ENSG00000047634.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SCML1
HGNCiHGNC:10580 SCML1
HPAiHPA035270
HPA035271
HPA061397
MIMi300227 gene
neXtProtiNX_Q9UN30
OpenTargetsiENSG00000047634
PharmGKBiPA34998

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3766 Eukaryota
ENOG410Y4AQ LUCA
GeneTreeiENSGT00940000164589
HOGENOMiHOG000036073
HOVERGENiHBG094812
InParanoidiQ9UN30
KOiK11464
OMAiYAYETKP
OrthoDBi298184at2759
PhylomeDBiQ9UN30

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6322

Protein Ontology

More...
PROi
PR:Q9UN30

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000047634 Expressed in 214 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiQ9UN30 baseline and differential
GenevisibleiQ9UN30 HS

Family and domain databases

InterProiView protein in InterPro
IPR001660 SAM
IPR013761 SAM/pointed_sf
PfamiView protein in Pfam
PF00536 SAM_1, 1 hit
SMARTiView protein in SMART
SM00454 SAM, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS50105 SAM_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCML1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UN30
Secondary accession number(s): B0FZN6
, B2RA08, Q5H968, Q5H969
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: July 28, 2009
Last modified: April 10, 2019
This is version 148 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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