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Entry version 162 (16 Oct 2019)
Sequence version 1 (01 May 2000)
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Protein

RNA-binding protein NOB1

Gene

NOB1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in mRNA degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi270ZincBy similarity1
Metal bindingi273ZincBy similarity1
Metal bindingi285ZincBy similarity1
Metal bindingi288ZincBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA-binding protein NOB1
Alternative name(s):
Phosphorylation regulatory protein HP-10
Protein ART-4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NOB1
Synonyms:ART4, NOB1P, PSMD8BP1
ORF Names:MSTP158
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29540 NOB1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
613586 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9ULX3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
28987

Open Targets

More...
OpenTargetsi
ENSG00000141101

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485585

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9ULX3

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NOB1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74753398

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002332652 – 412RNA-binding protein NOB1Add BLAST411

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei184PhosphoserineCombined sources1
Modified residuei201PhosphoserineCombined sources1
Modified residuei325PhosphoserineCombined sources1
Modified residuei352PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9ULX3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9ULX3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9ULX3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9ULX3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ULX3

PeptideAtlas

More...
PeptideAtlasi
Q9ULX3

PRoteomics IDEntifications database

More...
PRIDEi
Q9ULX3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85145

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ULX3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ULX3

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9ULX3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in liver, lung, placenta, endothelial cells and spleen.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000141101 Expressed in 90 organ(s), highest expression level in body of pancreas

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9ULX3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ULX3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA041522
HPA049430
HPA067411

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with UPF2.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
118808, 49 interactors

Protein interaction database and analysis system

More...
IntActi
Q9ULX3, 27 interactors

Molecular INTeraction database

More...
MINTi
Q9ULX3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000268802

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ULX3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 108PINcAdd BLAST104

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi185 – 191Poly-Glu7

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NOB1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2463 Eukaryota
COG1439 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015857

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000159692

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ULX3

KEGG Orthology (KO)

More...
KOi
K11883

Identification of Orthologs from Complete Genome Data

More...
OMAi
KVISLTY

Database of Orthologous Groups

More...
OrthoDBi
765237at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ULX3

TreeFam database of animal gene trees

More...
TreeFami
TF105838

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.120, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039907 NOB1
IPR017117 Nob1_euk
IPR036283 NOB1_Zf-like_sf
IPR014881 NOB1_Zn-bd
IPR002716 PIN_dom
IPR033411 Ribonuclease_PIN
IPR033461 WRNPLPNID

The PANTHER Classification System

More...
PANTHERi
PTHR12814 PTHR12814, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08772 NOB1_Zn_bind, 1 hit
PF17146 PIN_6, 1 hit
PF15017 WRNPLPNID, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037125 D-site_20S_pre-rRNA_nuclease, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00670 PINc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF144206 SSF144206, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9ULX3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPVEHVVAD AGAFLRHAAL QDIGKNIYTI REVVTEIRDK ATRRRLAVLP
60 70 80 90 100
YELRFKEPLP EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV
110 120 130 140 150
SHLKQEPQKV KVSSSIQHPE TPLHISGFHL PYKPKPPQET EKGHSACEPE
160 170 180 190 200
NLEFSSFMFW RNPLPNIDHE LQELLIDRGE DVPSEEEEEE ENGFEDRKDD
210 220 230 240 250
SDDDGGGWIT PSNIKQIQQE LEQCDVPEDV RVGCLTTDFA MQNVLLQMGL
260 270 280 290 300
HVLAVNGMLI REARSYILRC HGCFKTTSDM SRVFCSHCGN KTLKKVSVTV
310 320 330 340 350
SDDGTLHMHF SRNPKVLNPR GLRYSLPTPK GGKYAINPHL TEDQRFPQLR
360 370 380 390 400
LSQKARQKTN VFAPDYIAGV SPFVENDISS RSATLQVRDS TLGAGRRRLN
410
PNASRKKFVK KR
Length:412
Mass (Da):46,675
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i369680A6DCFC7CB0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BUR4H3BUR4_HUMAN
RNA-binding protein NOB1
NOB1
66Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ13705 differs from that shown. Reason: Frameshift.Curated
The sequence BAA91473 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti408F → L in AAQ13705 (Ref. 6) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050287231R → Q1 PublicationCorresponds to variant dbSNP:rs3811348Ensembl.1
Natural variantiVAR_050288366Y → F. Corresponds to variant dbSNP:rs1075935Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB026125 mRNA Translation: BAA86961.1
AY487344 mRNA Translation: AAR85357.1
AK001028 mRNA Translation: BAA91473.1 Frameshift.
BC000050 mRNA Translation: AAH00050.2
BC064630 mRNA Translation: AAH64630.1
AF190161 mRNA Translation: AAQ13705.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10884.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A61382

NCBI Reference Sequences

More...
RefSeqi
NP_054781.1, NM_014062.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000268802; ENSP00000268802; ENSG00000141101

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
28987

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:28987

UCSC genome browser

More...
UCSCi
uc002exs.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026125 mRNA Translation: BAA86961.1
AY487344 mRNA Translation: AAR85357.1
AK001028 mRNA Translation: BAA91473.1 Frameshift.
BC000050 mRNA Translation: AAH00050.2
BC064630 mRNA Translation: AAH64630.1
AF190161 mRNA Translation: AAQ13705.1 Frameshift.
CCDSiCCDS10884.1
PIRiA61382
RefSeqiNP_054781.1, NM_014062.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6G18electron microscopy3.60y1-412[»]
6G4Selectron microscopy4.00y1-412[»]
6G51electron microscopy4.10y1-412[»]
6G53electron microscopy4.50y1-412[»]
6G5Ielectron microscopy3.50y1-412[»]
SMRiQ9ULX3
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi118808, 49 interactors
IntActiQ9ULX3, 27 interactors
MINTiQ9ULX3
STRINGi9606.ENSP00000268802

PTM databases

iPTMnetiQ9ULX3
PhosphoSitePlusiQ9ULX3
SwissPalmiQ9ULX3

Polymorphism and mutation databases

BioMutaiNOB1
DMDMi74753398

Proteomic databases

EPDiQ9ULX3
jPOSTiQ9ULX3
MassIVEiQ9ULX3
MaxQBiQ9ULX3
PaxDbiQ9ULX3
PeptideAtlasiQ9ULX3
PRIDEiQ9ULX3
ProteomicsDBi85145

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
28987

Genome annotation databases

EnsembliENST00000268802; ENSP00000268802; ENSG00000141101
GeneIDi28987
KEGGihsa:28987
UCSCiuc002exs.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
28987
DisGeNETi28987

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NOB1
HGNCiHGNC:29540 NOB1
HPAiHPA041522
HPA049430
HPA067411
MIMi613586 gene
neXtProtiNX_Q9ULX3
OpenTargetsiENSG00000141101
PharmGKBiPA143485585

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2463 Eukaryota
COG1439 LUCA
GeneTreeiENSGT00390000015857
HOGENOMiHOG000159692
InParanoidiQ9ULX3
KOiK11883
OMAiKVISLTY
OrthoDBi765237at2759
PhylomeDBiQ9ULX3
TreeFamiTF105838

Enzyme and pathway databases

ReactomeiR-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
NOB1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
28987
PharosiQ9ULX3

Protein Ontology

More...
PROi
PR:Q9ULX3

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000141101 Expressed in 90 organ(s), highest expression level in body of pancreas
ExpressionAtlasiQ9ULX3 baseline and differential
GenevisibleiQ9ULX3 HS

Family and domain databases

Gene3Di3.30.40.120, 1 hit
InterProiView protein in InterPro
IPR039907 NOB1
IPR017117 Nob1_euk
IPR036283 NOB1_Zf-like_sf
IPR014881 NOB1_Zn-bd
IPR002716 PIN_dom
IPR033411 Ribonuclease_PIN
IPR033461 WRNPLPNID
PANTHERiPTHR12814 PTHR12814, 1 hit
PfamiView protein in Pfam
PF08772 NOB1_Zn_bind, 1 hit
PF17146 PIN_6, 1 hit
PF15017 WRNPLPNID, 1 hit
PIRSFiPIRSF037125 D-site_20S_pre-rRNA_nuclease, 1 hit
SMARTiView protein in SMART
SM00670 PINc, 1 hit
SUPFAMiSSF144206 SSF144206, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOB1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ULX3
Secondary accession number(s): Q7L6B7
, Q7M4M4, Q7Z4B5, Q9NWB0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: May 1, 2000
Last modified: October 16, 2019
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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