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Protein

Protein phosphatase 1H

Gene

PPM1H

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.1 Publication

Miscellaneous

May act as a suppressor of trastuzumab resistance.1 Publication

Caution

A report observed N-glycosylation at Asn-354 (PubMed:19139490). However, as the protein is not predicted to localize in an extracellular compartment of the cell, additional evidences are required to confirm this result.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • phosphoprotein phosphatase activity Source: UniProtKB
  • protein serine/threonine phosphatase activity Source: InterPro

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphatase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein phosphatase 1H (EC:3.1.3.16)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PPM1H
Synonyms:ARHCL1, KIAA1157, URCC2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000111110.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18583 PPM1H

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616016 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9ULR3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi153H → L: Decreased enzymatic activity. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
57460

Open Targets

More...
OpenTargetsi
ENSG00000111110

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38354

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PPM1H

Domain mapping of disease mutations (DMDM)

More...
DMDMi
147721250

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002866031 – 514Protein phosphatase 1HAdd BLAST514

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei7PhosphoserineBy similarity1
Modified residuei113PhosphothreonineBy similarity1
Modified residuei124PhosphoserineCombined sources1
Modified residuei211PhosphoserineCombined sources1
Modified residuei213Omega-N-methylarginineBy similarity1
Modified residuei221PhosphoserineCombined sources1
Modified residuei224PhosphothreonineCombined sources1
Modified residuei422PhosphoserineCombined sources1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9ULR3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9ULR3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ULR3

PeptideAtlas

More...
PeptideAtlasi
Q9ULR3

PRoteomics IDEntifications database

More...
PRIDEi
Q9ULR3

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85100

PTM databases

DEPOD human dephosphorylation database

More...
DEPODi
Q9ULR3

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ULR3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ULR3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000111110 Expressed in 201 organ(s), highest expression level in paraflocculus

CleanEx database of gene expression profiles

More...
CleanExi
HS_PPM1H

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ULR3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB020694
HPA044244
HPA058777

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121530, 96 interactors

Protein interaction database and analysis system

More...
IntActi
Q9ULR3, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9ULR3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini77 – 507PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST431

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1323 Eukaryota
ENOG410XP4B LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160095

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000251606

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG105802

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ULR3

KEGG Orthology (KO)

More...
KOi
K17503

Identification of Orthologs from Complete Genome Data

More...
OMAi
GYAECIN

Database of Orthologous Groups

More...
OrthoDBi
EOG091G05FH

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ULR3

TreeFam database of animal gene trees

More...
TreeFami
TF314700

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00143 PP2Cc, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom

The PANTHER Classification System

More...
PANTHERi
PTHR13832 PTHR13832, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00481 PP2C, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00332 PP2Cc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81606 SSF81606, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51746 PPM_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9ULR3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLTRVKSAVA NFMGGIMAGS SGSEHGGGSC GGSDLPLRFP YGRPEFLGLS
60 70 80 90 100
QDEVECSADH IARPILILKE TRRLPWATGY AEVINAGKST HNEDQASCEV
110 120 130 140 150
LTVKKKAGAV TSTPNRNSSK RRSSLPNGEG LQLKENSESE GVSCHYWSLF
160 170 180 190 200
DGHAGSGAAV VASRLLQHHI TEQLQDIVDI LKNSAVLPPT CLGEEPENTP
210 220 230 240 250
ANSRTLTRAA SLRGGVGAPG SPSTPPTRFF TEKKIPHECL VIGALESAFK
260 270 280 290 300
EMDLQIERER SSYNISGGCT ALIVICLLGK LYVANAGDSR AIIIRNGEII
310 320 330 340 350
PMSSEFTPET ERQRLQYLAF MQPHLLGNEF THLEFPRRVQ RKELGKKMLY
360 370 380 390 400
RDFNMTGWAY KTIEDEDLKF PLIYGEGKKA RVMATIGVTR GLGDHDLKVH
410 420 430 440 450
DSNIYIKPFL SSAPEVRIYD LSKYDHGSDD VLILATDGLW DVLSNEEVAE
460 470 480 490 500
AITQFLPNCD PDDPHRYTLA AQDLVMRARG VLKDRGWRIS NDRLGSGDDI
510
SVYVIPLIHG NKLS
Length:514
Mass (Da):56,448
Last modified:May 15, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9348C6AC3D74D1B7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti77A → V in AAI57844 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB084258 mRNA Translation: BAG16181.1
AC023359 Genomic DNA No translation available.
AC025264 Genomic DNA No translation available.
AC048341 Genomic DNA No translation available.
AC078814 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97112.1
BC157843 mRNA Translation: AAI57844.1
AB032983 mRNA Translation: BAA86471.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44934.1

NCBI Reference Sequences

More...
RefSeqi
NP_065751.1, NM_020700.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.435479

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000228705; ENSP00000228705; ENSG00000111110

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57460

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57460

UCSC genome browser

More...
UCSCi
uc001srk.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB084258 mRNA Translation: BAG16181.1
AC023359 Genomic DNA No translation available.
AC025264 Genomic DNA No translation available.
AC048341 Genomic DNA No translation available.
AC078814 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW97112.1
BC157843 mRNA Translation: AAI57844.1
AB032983 mRNA Translation: BAA86471.1
CCDSiCCDS44934.1
RefSeqiNP_065751.1, NM_020700.1
UniGeneiHs.435479

3D structure databases

ProteinModelPortaliQ9ULR3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121530, 96 interactors
IntActiQ9ULR3, 1 interactor

PTM databases

DEPODiQ9ULR3
iPTMnetiQ9ULR3
PhosphoSitePlusiQ9ULR3

Polymorphism and mutation databases

BioMutaiPPM1H
DMDMi147721250

Proteomic databases

EPDiQ9ULR3
MaxQBiQ9ULR3
PaxDbiQ9ULR3
PeptideAtlasiQ9ULR3
PRIDEiQ9ULR3
ProteomicsDBi85100

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
57460
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000228705; ENSP00000228705; ENSG00000111110
GeneIDi57460
KEGGihsa:57460
UCSCiuc001srk.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57460
DisGeNETi57460
EuPathDBiHostDB:ENSG00000111110.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PPM1H

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0018169
HGNCiHGNC:18583 PPM1H
HPAiCAB020694
HPA044244
HPA058777
MIMi616016 gene
neXtProtiNX_Q9ULR3
OpenTargetsiENSG00000111110
PharmGKBiPA38354

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1323 Eukaryota
ENOG410XP4B LUCA
GeneTreeiENSGT00940000160095
HOGENOMiHOG000251606
HOVERGENiHBG105802
InParanoidiQ9ULR3
KOiK17503
OMAiGYAECIN
OrthoDBiEOG091G05FH
PhylomeDBiQ9ULR3
TreeFamiTF314700

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PPM1H human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57460

Protein Ontology

More...
PROi
PR:Q9ULR3

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000111110 Expressed in 201 organ(s), highest expression level in paraflocculus
CleanExiHS_PPM1H
GenevisibleiQ9ULR3 HS

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 2 hits
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPPM1H_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ULR3
Secondary accession number(s): B1Q2A9, B2RXG4, Q6PI86
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: December 5, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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