Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 162 (31 Jul 2019)
Sequence version 2 (21 Feb 2002)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Zinc finger protein 490

Gene

ZNF490

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri156 – 178C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri194 – 216C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri222 – 244C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri250 – 272C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri278 – 300C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri306 – 328C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri334 – 356C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri362 – 384C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri390 – 412C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri418 – 440C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri446 – 468C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri474 – 496C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri502 – 524C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 490
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF490
Synonyms:KIAA1198
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23705 ZNF490

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9ULM2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000188033

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134990049

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF490

Domain mapping of disease mutations (DMDM)

More...
DMDMi
20140911

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476131 – 529Zinc finger protein 490Add BLAST529

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9ULM2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9ULM2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9ULM2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ULM2

PeptideAtlas

More...
PeptideAtlasi
Q9ULM2

PRoteomics IDEntifications database

More...
PRIDEi
Q9ULM2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
85077

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ULM2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ULM2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000188033 Expressed in 129 organ(s), highest expression level in buccal mucosa cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9ULM2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ULM2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA005576

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121544, 28 interactors

Protein interaction database and analysis system

More...
IntActi
Q9ULM2, 26 interactors

Molecular INTeraction database

More...
MINTi
Q9ULM2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000311521

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ULM2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini57 – 132KRABPROSITE-ProRule annotationAdd BLAST76

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri156 – 178C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri194 – 216C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri222 – 244C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri250 – 272C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri278 – 300C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri306 – 328C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri334 – 356C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri362 – 384C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri390 – 412C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri418 – 440C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri446 – 468C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri474 – 496C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri502 – 524C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164491

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ULM2

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
CENKEDR

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ULM2

TreeFam database of animal gene trees

More...
TreeFami
TF338854

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 13 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 13 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9ULM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRNSSLSFQ MERPLEEQVQ SKWSSSQGRT GTGGSDVLQM QNSEHHGQSI
60 70 80 90 100
KTQTDSISLE DVAVNFTLEE WALLDPGQRN IYRDVMRATF KNLACIGEKW
110 120 130 140 150
KDQDIEDEHK NQGRNLRSPM VEALCENKED CPCGKSTSQI PDLNTNLETP
160 170 180 190 200
TGLKPCDCSV CGEVFMHQVS LNRHMRSHTE QKPNECHEYG EKPHKCKECG
210 220 230 240 250
KTFTRSSSIR THERIHTGEK PYECKECGKA FAFLFSFRNH IRIHTGETPY
260 270 280 290 300
ECKECGKAFR YLTALRRHEK NHTGEKPYKC KQCGKAFIYY QPFLTHERTH
310 320 330 340 350
TGEKPYECKQ CGKAFSCPTY LRSHEKTHTG EKPFVCRECG RAFFSHSSLR
360 370 380 390 400
KHVKTHTGVQ PYTCKKCGEA FKSSSSCEVH ERTHFGEKPY ECKQCGKAFN
410 420 430 440 450
SSSYLQLHER VHTGEKTYEC KECGKAFLYS THFRIHERTH TREKPYECKQ
460 470 480 490 500
CGRVFIYFSH LRRHERSHTG VKPCECKQCG KAFTCLNSLK VHKRIHTGER
510 520
PFQCRQCGKA FSYSKSLHVH ERTHSRQKP
Length:529
Mass (Da):61,340
Last modified:February 21, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iECBA528D4808153C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JID3C9JID3_HUMAN
Zinc finger protein 490
ZNF490
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WDW6F8WDW6_HUMAN
Zinc finger protein 490
ZNF490
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA86512 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB033024 mRNA Translation: BAA86512.1 Different initiation.
BC038586 mRNA Translation: AAH38586.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12272.1

NCBI Reference Sequences

More...
RefSeqi
NP_065765.1, NM_020714.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000311437; ENSP00000311521; ENSG00000188033

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57474

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57474

UCSC genome browser

More...
UCSCi
uc002mtz.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB033024 mRNA Translation: BAA86512.1 Different initiation.
BC038586 mRNA Translation: AAH38586.1
CCDSiCCDS12272.1
RefSeqiNP_065765.1, NM_020714.2

3D structure databases

SMRiQ9ULM2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi121544, 28 interactors
IntActiQ9ULM2, 26 interactors
MINTiQ9ULM2
STRINGi9606.ENSP00000311521

PTM databases

iPTMnetiQ9ULM2
PhosphoSitePlusiQ9ULM2

Polymorphism and mutation databases

BioMutaiZNF490
DMDMi20140911

Proteomic databases

EPDiQ9ULM2
jPOSTiQ9ULM2
MaxQBiQ9ULM2
PaxDbiQ9ULM2
PeptideAtlasiQ9ULM2
PRIDEiQ9ULM2
ProteomicsDBi85077

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
57474
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000311437; ENSP00000311521; ENSG00000188033
GeneIDi57474
KEGGihsa:57474
UCSCiuc002mtz.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57474

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF490
HGNCiHGNC:23705 ZNF490
HPAiHPA005576
neXtProtiNX_Q9ULM2
OpenTargetsiENSG00000188033
PharmGKBiPA134990049

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000164491
HOGENOMiHOG000234617
InParanoidiQ9ULM2
KOiK09228
OMAiCENKEDR
OrthoDBi1318335at2759
PhylomeDBiQ9ULM2
TreeFamiTF338854

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57474

Protein Ontology

More...
PROi
PR:Q9ULM2

Gene expression databases

BgeeiENSG00000188033 Expressed in 129 organ(s), highest expression level in buccal mucosa cell
ExpressionAtlasiQ9ULM2 baseline and differential
GenevisibleiQ9ULM2 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 7 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 13 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 13 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN490_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ULM2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: February 21, 2002
Last modified: July 31, 2019
This is version 162 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again