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Entry version 122 (12 Aug 2020)
Sequence version 3 (26 Feb 2008)
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Protein

NACHT and WD repeat domain-containing protein 2

Gene

NWD2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9ULI1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
NACHT and WD repeat domain-containing protein 2
Alternative name(s):
Leucine-rich repeat and WD repeat-containing protein KIAA1239
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NWD2
Synonyms:KIAA1239
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000174145.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29229, NWD2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9ULI1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
57495

Open Targets

More...
OpenTargetsi
ENSG00000174145

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA145148614

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9ULI1, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NWD2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
172044833

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003209201 – 1742NACHT and WD repeat domain-containing protein 2Add BLAST1742

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9ULI1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9ULI1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ULI1

PeptideAtlas

More...
PeptideAtlasi
Q9ULI1

PRoteomics IDEntifications database

More...
PRIDEi
Q9ULI1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85034

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ULI1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ULI1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000174145, Expressed in dorsolateral prefrontal cortex and 74 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ULI1, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000174145, Tissue enhanced (brain, breast)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
121562, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000309501

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9ULI1, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati386 – 410LRR 1Add BLAST25
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini410 – 737NACHTAdd BLAST328
Repeati677 – 698LRR 2Add BLAST22
Repeati724 – 747LRR 3Add BLAST24
Repeati883 – 906LRR 4Add BLAST24
Repeati925 – 953LRR 5Add BLAST29
Repeati963 – 1004WD 1Add BLAST42
Repeati1007 – 1046WD 2Add BLAST40
Repeati1140 – 1179WD 3Add BLAST40
Repeati1229 – 1271WD 4Add BLAST43
Repeati1272 – 1311WD 5Add BLAST40
Repeati1314 – 1353WD 6Add BLAST40
Repeati1355 – 1394WD 7Add BLAST40
Repeati1396 – 1434WD 8Add BLAST39
Repeati1476 – 1516WD 9Add BLAST41
Repeati1522 – 1564WD 10Add BLAST43
Repeati1614 – 1653WD 11Add BLAST40

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Leucine-rich repeat, Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3602, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153648

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003267_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ULI1

Identification of Orthologs from Complete Genome Data

More...
OMAi
NSCYDRV

Database of Orthologous Groups

More...
OrthoDBi
20367at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ULI1

TreeFam database of animal gene trees

More...
TreeFami
TF332647

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007111, NACHT_NTPase
IPR027417, P-loop_NTPase
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05729, NACHT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320, WD40, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978, SSF50978, 2 hits
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00678, WD_REPEATS_1, 1 hit
PS50294, WD_REPEATS_REGION, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9ULI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWPAGAGTKL PCPRDSALRR AAFSGNLTAL PSHLVPAGRS VRVFISANPE
60 70 80 90 100
DTGAERQALR ENVYPKLREF CRENYGLEFQ VIDLYWGVEE DEWDSPELQK
110 120 130 140 150
TRMKLLENCL KTSAGPCFVG LLGEKYGNIR IPGEVEASEF EMILDAAIEA
160 170 180 190 200
KLETKLLEEW YCRDENSVPA AYYLRPKSEM LRSNRNAMQP STNAENEKTW
210 220 230 240 250
QEISDEIKKI FKAAVKLLHE KGKMKHSQAK RYLFSAIEDE FDFALGKQTP
260 270 280 290 300
AFLKKCVCYI RKIANIERFV KIPEMGKYMD ITGTEPRIIR DPEAQEKLIK
310 320 330 340 350
LRDEFIPTIV ASSNLRVYTS VTHCDMKLGY SQEIENHYIE GLGKQFYEDM
360 370 380 390 400
IDIIQATIQQ NFDTETDTLY DEILQHSSLC KTYASFYEYK CESLNIVHNY
410 420 430 440 450
ILPSKAGHIN PLIIYGGPCT GKTLLLAEVA KKAYGWLHED TGPESDPVVI
460 470 480 490 500
VRFLGTTDMS SDLRTLLLSV CEQLAVNYRC LVQSYPKKIH DLCDLFINLL
510 520 530 540 550
NESSLQRPLV IIFDALEQLS ENDDARKLWW LPAHLPRFVR IVLSTLPNKH
560 570 580 590 600
GILQKLRCLI HEEDNYIELI PRDRKMCSQV LKHQLLRVKR KVTSGQQIYV
610 620 630 640 650
NNALSKCTLP MFVNLTFREV RHWRSHKDVD ESSLSVTVHE SIEQLFWSLE
660 670 680 690 700
KKCGQKLVSR ALGYITMAKM GLSEMELEDV LALDNSVMSE LKENTRPSNP
710 720 730 740 750
LRVPYLYIAR LKEGLSGYLI ERHVKNVTLL VWANRHLQLI AQKLYLQDDN
760 770 780 790 800
DLREMHTILA DYFLGVWSGG RRKAFCLEDP YLNGCLDLEN RSLLEEEKHF
810 820 830 840 850
MEQASFDRQA PDQPWVFQCN PLEPDIFFVN HRKMSELLYH LTRCGKTDDL
860 870 880 890 900
LYGIIMNFSW LYTMIKIGQF DKVLSDIELA YNYSQEKELK FLANTLRSIK
910 920 930 940 950
NKVTAFPGSL SAELQQRLLP VVSSLPKLRH LLLECDKDGP KYCSIVPLHS
960 970 980 990 1000
SMDVTYSPER LPLSSSHLHV TEILPTCNPS TVLTALENGS ISTWDVETRQ
1010 1020 1030 1040 1050
LLRQITTAQS VILGMKLTSD EKYLVVATTN NTLLIYDNVN SCLLSEVEIK
1060 1070 1080 1090 1100
GTKHGSSATY INGFTLSANH ALAWLEASKD VTVIDLLYGW PLYQFHCWYE
1110 1120 1130 1140 1150
VTCVQCSLDG LYAFCGQYLN TTTIFHLGSG EKLCTVTSEF SGGFVKFLLI
1160 1170 1180 1190 1200
LDTAQEMVMV DSEGSLSVWN TEDISSPQLT DDFDCRREDS EVVSIELSED
1210 1220 1230 1240 1250
QSAVLICKAL SIELLDTGLW KVAEKFRAKH NERFISAVLS KNGDCIIATM
1260 1270 1280 1290 1300
ENTSAVFFWR RDTGQCMASL QEISGSIVKL VKSSHHNMLL SLSTSGVLSI
1310 1320 1330 1340 1350
WDIDIITAMS NIDKTGKPIQ SLLLPARGEI IYSLDGSDCV HKWNFSSGFI
1360 1370 1380 1390 1400
EAVFKHEGIV EHCVLTSTGD IMVTSDDKSS QYVWHTSSGE NLFRINGQRI
1410 1420 1430 1440 1450
SQLLITHNDQ FVVSLCEENA SRVWRLATGH RVCNILTTLQ NAFITSANTF
1460 1470 1480 1490 1500
VVGMTKSKVL AVSLWTGSIT KKFCCEDGTT IVNFKLIPDC PDIIVFITSA
1510 1520 1530 1540 1550
ETVNIWSLTD EVICRRVQLP NNFLKNLEDF EISPNGKLGI IARGDENINV
1560 1570 1580 1590 1600
LDLYSGKLRV VHASGIIWRQ RLSRDGRYLV YICFRNGEEE DENGAIFSLI
1610 1620 1630 1640 1650
VMRLADGKNI GACSLYKTPT FLALSQRHLN IIVGFDDGSI GIYTVVDRVD
1660 1670 1680 1690 1700
AALKIKIATS NSRQIFNNAT HTSRPKCNSY CFKISVDCLW RESTEVFARD
1710 1720 1730 1740
SPITVSDSTE SNEATPSKKH NSCYERVCSA LEARGHSYAP DN
Length:1,742
Mass (Da):197,466
Last modified:February 26, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFBD5E5281EA54C36
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_039304569L → M. Corresponds to variant dbSNP:rs4634233Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC022463 Genomic DNA No translation available.
AB033065 mRNA Translation: BAA86553.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47040.1

NCBI Reference Sequences

More...
RefSeqi
NP_001138462.1, NM_001144990.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000309447; ENSP00000309501; ENSG00000174145

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
57495

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:57495

UCSC genome browser

More...
UCSCi
uc011bxz.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022463 Genomic DNA No translation available.
AB033065 mRNA Translation: BAA86553.2
CCDSiCCDS47040.1
RefSeqiNP_001138462.1, NM_001144990.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi121562, 1 interactor
STRINGi9606.ENSP00000309501

PTM databases

iPTMnetiQ9ULI1
PhosphoSitePlusiQ9ULI1

Polymorphism and mutation databases

BioMutaiNWD2
DMDMi172044833

Proteomic databases

MassIVEiQ9ULI1
MaxQBiQ9ULI1
PaxDbiQ9ULI1
PeptideAtlasiQ9ULI1
PRIDEiQ9ULI1
ProteomicsDBi85034

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
71143, 3 antibodies

Genome annotation databases

EnsembliENST00000309447; ENSP00000309501; ENSG00000174145
GeneIDi57495
KEGGihsa:57495
UCSCiuc011bxz.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57495
DisGeNETi57495
EuPathDBiHostDB:ENSG00000174145.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NWD2
HGNCiHGNC:29229, NWD2
HPAiENSG00000174145, Tissue enhanced (brain, breast)
neXtProtiNX_Q9ULI1
OpenTargetsiENSG00000174145
PharmGKBiPA145148614

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3602, Eukaryota
GeneTreeiENSGT00940000153648
HOGENOMiCLU_003267_0_0_1
InParanoidiQ9ULI1
OMAiNSCYDRV
OrthoDBi20367at2759
PhylomeDBiQ9ULI1
TreeFamiTF332647

Enzyme and pathway databases

PathwayCommonsiQ9ULI1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
57495, 5 hits in 866 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
57495
PharosiQ9ULI1, Tdark

Protein Ontology

More...
PROi
PR:Q9ULI1
RNActiQ9ULI1, protein

Gene expression databases

BgeeiENSG00000174145, Expressed in dorsolateral prefrontal cortex and 74 other tissues
GenevisibleiQ9ULI1, HS

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR007111, NACHT_NTPase
IPR027417, P-loop_NTPase
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF05729, NACHT, 1 hit
SMARTiView protein in SMART
SM00320, WD40, 5 hits
SUPFAMiSSF50978, SSF50978, 2 hits
SSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00678, WD_REPEATS_1, 1 hit
PS50294, WD_REPEATS_REGION, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNWD2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ULI1
Secondary accession number(s): A8MRU1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: August 12, 2020
This is version 122 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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