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Entry version 131 (17 Jun 2020)
Sequence version 3 (13 Nov 2007)
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Protein

Protein WWC3

Gene

WWC3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein WWC3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WWC3
Synonyms:KIAA1280
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000047644.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29237 WWC3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9ULE0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55841

Open Targets

More...
OpenTargetsi
ENSG00000047644

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485672

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9ULE0 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
WWC3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
160261727

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002444941 – 1092Protein WWC3Add BLAST1092

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9ULE0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9ULE0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9ULE0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ULE0

PeptideAtlas

More...
PeptideAtlasi
Q9ULE0

PRoteomics IDEntifications database

More...
PRIDEi
Q9ULE0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
85006 [Q9ULE0-1]
85007 [Q9ULE0-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ULE0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ULE0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000047644 Expressed in upper lobe of lung and 228 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ULE0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000047644 Tissue enhanced (ductus)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120944, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q9ULE0, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000370242

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9ULE0 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ULE0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini598 – 723C2PROSITE-ProRule annotationAdd BLAST126

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili40 – 126Sequence analysisAdd BLAST87
Coiled coili230 – 344Sequence analysisAdd BLAST115
Coiled coili761 – 812Sequence analysisAdd BLAST52
Coiled coili967 – 1036Sequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi347 – 466Ser-richAdd BLAST120

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the WWC family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410ISXH Eukaryota
ENOG410XSXK LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00410000025556

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ULE0

Identification of Orthologs from Complete Genome Data

More...
OMAi
VYVKVHL

Database of Orthologous Groups

More...
OrthoDBi
364990at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ULE0

TreeFam database of animal gene trees

More...
TreeFami
TF324040

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08680 C2_Kibra, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035892 C2_domain_sf
IPR037771 C2_WWC

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004 C2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9ULE0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDHINKLTQI EDPREQWRRE QERMLKEYLI VAQEALNAKK EIYQIKQQRF
60 70 80 90 100
ELAQEEYQQL HKMCEDDSRS YASSFSGYST NTKYDPHQIK AEIASRRDRL
110 120 130 140 150
SRLKRELTQM KQELQYKEKG VETLQEIDRK MSSTHTSYKL DEAQAIMSEL
160 170 180 190 200
RTIKKAICTG EKERRDLMHS LAKLTDSFKN SCSVTDSLVD FPHHVGVPGD
210 220 230 240 250
AGVPQQFCDA GSQTDIIGEF VFDDKTRLVD RVRLNWQYEE ARKRVANIQQ
260 270 280 290 300
QLARLDNESW PSTAEADRDR LQLIKEKEAL LQELQLIIAQ RRSAGDVARL
310 320 330 340 350
EEERERLEEE LRRARATSAQ GATERILLQE KRNCLLMQLE EATRLTSYLQ
360 370 380 390 400
SQLKSLCAST LTVSSGSSRG SLASSRGSLA SSRGSLSSVS FTDIYGLPQY
410 420 430 440 450
EKPDAEGSQL LRFDLIPFDS LGRDAPFSEP PGPSGFHKQR RSLDTPQSLA
460 470 480 490 500
SLSSRSSLSS LSPPSSPLDT PFLPASRDSP LAQLADSCEG PGLGALDRLR
510 520 530 540 550
AHASAMGDED LPGMAALQPH GVPGDGEGPH ERGPPPASAP VGGTVTLRED
560 570 580 590 600
SAKRLERRAR RISACLSDYS LASDSGVFEP LTKRNEDAEE PAYGDTASNG
610 620 630 640 650
DPQIHVGLLR DSGSECLLVH VLQLKNPAGL AVKEDCKVHI RVYLPPLDSG
660 670 680 690 700
TPNTYCSKAL EFQVPLVFNE VFRIPVHSSA LTLKSLQLYV CSVTPQLQEE
710 720 730 740 750
LLGIAQINLA DYDSLSEMQL RWHSVQVFTS SEPSRTREAG CAGESSARDP
760 770 780 790 800
AHTISISGKT DAVTVLLART TAQLQAVERE LAEERAKLEY TEEEVLEMER
810 820 830 840 850
KEEQAEAISE RSWQADSVDS GCSNCTQTSP PYPEPCCMGI DSILGHPFAA
860 870 880 890 900
QAGPYSPEKF QPSPLKVDKE TNTEDLFLEE AASLVKERPS RRARGSPFVR
910 920 930 940 950
SGTIVRSQTF SPGARSQYVC RLYRSDSDSS TLPRKSPFVR NTLERRTLRY
960 970 980 990 1000
KQSCRSSLAE LMARTSLDLE LDLQASRTRQ RQLNEELCAL RELRQRLEDA
1010 1020 1030 1040 1050
QLRGQTDLPP WVLRDERLRG LLREAERQTR QTKLDYRHEQ AAEKMLKKAS
1060 1070 1080 1090
KEIYQLRGQS HKEPIQVQTF REKIAFFTRP RINIPPLPAD DV
Length:1,092
Mass (Da):122,676
Last modified:November 13, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i742C698715617C2C
GO
Isoform 2 (identifier: Q9ULE0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     544-582: TVTLREDSAK...SDSGVFEPLT → SKCSLSDSSR...LFASQRQWGV
     583-1092: Missing.

Show »
Length:582
Mass (Da):65,049
Checksum:iA043FE4E2158F906
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAH56367 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_036969495A → T. Corresponds to variant dbSNP:rs5934750Ensembl.1
Natural variantiVAR_036970593Y → C. Corresponds to variant dbSNP:rs36076296Ensembl.1
Natural variantiVAR_062109831P → L. Corresponds to variant dbSNP:rs55787431Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_029220544 – 582TVTLR…FEPLT → SKCSLSDSSRRQCQEVGEEG TPHLRMSVGLFASQRQWGV in isoform 2. 1 PublicationAdd BLAST39
Alternative sequenceiVSP_029221583 – 1092Missing in isoform 2. 1 PublicationAdd BLAST510

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK292961 mRNA Translation: BAF85650.1
AC002359 Genomic DNA No translation available.
AC002364 Genomic DNA No translation available.
AC121345 Genomic DNA No translation available.
AB033106 mRNA Translation: BAA86594.1
AL353937 mRNA Translation: CAH56367.1 Frameshift.
CH471074 Genomic DNA Translation: EAW98775.1
BC003527 mRNA Translation: AAH03527.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14136.1 [Q9ULE0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_056506.2, NM_015691.3 [Q9ULE0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000380861; ENSP00000370242; ENSG00000047644 [Q9ULE0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55841

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55841

UCSC genome browser

More...
UCSCi
uc004csx.5 human [Q9ULE0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK292961 mRNA Translation: BAF85650.1
AC002359 Genomic DNA No translation available.
AC002364 Genomic DNA No translation available.
AC121345 Genomic DNA No translation available.
AB033106 mRNA Translation: BAA86594.1
AL353937 mRNA Translation: CAH56367.1 Frameshift.
CH471074 Genomic DNA Translation: EAW98775.1
BC003527 mRNA Translation: AAH03527.1
CCDSiCCDS14136.1 [Q9ULE0-1]
RefSeqiNP_056506.2, NM_015691.3 [Q9ULE0-1]

3D structure databases

SMRiQ9ULE0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120944, 11 interactors
IntActiQ9ULE0, 3 interactors
STRINGi9606.ENSP00000370242

PTM databases

iPTMnetiQ9ULE0
PhosphoSitePlusiQ9ULE0

Polymorphism and mutation databases

BioMutaiWWC3
DMDMi160261727

Proteomic databases

EPDiQ9ULE0
jPOSTiQ9ULE0
MassIVEiQ9ULE0
PaxDbiQ9ULE0
PeptideAtlasiQ9ULE0
PRIDEiQ9ULE0
ProteomicsDBi85006 [Q9ULE0-1]
85007 [Q9ULE0-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
49640 71 antibodies

Genome annotation databases

EnsembliENST00000380861; ENSP00000370242; ENSG00000047644 [Q9ULE0-1]
GeneIDi55841
KEGGihsa:55841
UCSCiuc004csx.5 human [Q9ULE0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55841
DisGeNETi55841
EuPathDBiHostDB:ENSG00000047644.17

GeneCards: human genes, protein and diseases

More...
GeneCardsi
WWC3
HGNCiHGNC:29237 WWC3
HPAiENSG00000047644 Tissue enhanced (ductus)
neXtProtiNX_Q9ULE0
OpenTargetsiENSG00000047644
PharmGKBiPA143485672

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410ISXH Eukaryota
ENOG410XSXK LUCA
GeneTreeiENSGT00410000025556
InParanoidiQ9ULE0
OMAiVYVKVHL
OrthoDBi364990at2759
PhylomeDBiQ9ULE0
TreeFamiTF324040

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
55841 0 hits in 407 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
WWC3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55841
PharosiQ9ULE0 Tbio

Protein Ontology

More...
PROi
PR:Q9ULE0
RNActiQ9ULE0 protein

Gene expression databases

BgeeiENSG00000047644 Expressed in upper lobe of lung and 228 other tissues
GenevisibleiQ9ULE0 HS

Family and domain databases

CDDicd08680 C2_Kibra, 1 hit
Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR035892 C2_domain_sf
IPR037771 C2_WWC
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWWC3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ULE0
Secondary accession number(s): A8KA96, Q659C1, Q9BTQ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 13, 2007
Last modified: June 17, 2020
This is version 131 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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