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Entry version 144 (16 Oct 2019)
Sequence version 3 (08 May 2019)
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Protein

Zinc finger protein 777

Gene

ZNF777

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri546 – 568C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri574 – 596C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri636 – 658C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri664 – 686C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri722 – 744C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri750 – 772C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri778 – 800C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri806 – 828C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 777
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF777
Synonyms:KIAA1285
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:22213 ZNF777

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9ULD5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000196453

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162410383

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9ULD5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF777

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152112417

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002936921 – 831Zinc finger protein 777Add BLAST831

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei47PhosphoserineCombined sources1
Modified residuei157PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki330Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki452Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei496PhosphoserineCombined sources1
Modified residuei502PhosphoserineCombined sources1
Modified residuei604PhosphoserineCombined sources1
Modified residuei623PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9ULD5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9ULD5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9ULD5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ULD5

PeptideAtlas

More...
PeptideAtlasi
Q9ULD5

PRoteomics IDEntifications database

More...
PRIDEi
Q9ULD5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ULD5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ULD5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000196453 Expressed in 171 organ(s), highest expression level in endothelial cell

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ULD5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA003252

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
118035, 55 interactors

Protein interaction database and analysis system

More...
IntActi
Q9ULD5, 19 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000247930

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ULD5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini285 – 356KRABPROSITE-ProRule annotationAdd BLAST72

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi338 – 467Glu-richAdd BLAST130

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri546 – 568C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri574 – 596C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri636 – 658C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri664 – 686C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri722 – 744C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri750 – 772C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri778 – 800C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri806 – 828C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155153

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000013125

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ULD5

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
ERGPAFN

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ULD5

TreeFam database of animal gene trees

More...
TreeFami
TF337777

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022137 DUF3669_Znf
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12417 DUF3669, 1 hit
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9ULD5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENQRSSPLS FPSVPQEETL RQAPAGLPRE TLFQSRVLPP KEIPSLSPTI
60 70 80 90 100
PRQGSLPQTS SAPKQETSGR MPHVLQKGPS LLCSAASEQE TSLQGPLASQ
110 120 130 140 150
EGTQYPPPAA AEQEVSLLSH SPHHQEAPVH SPEAPEKDPL TLSPTVPETD
160 170 180 190 200
MDPLLQSPVS QKDTPFQISS AVQKEQPLPT AEITRLAVWA AVQAVERKLE
210 220 230 240 250
AQAMRLLTLE GRTGTNEKKI ADCEKTAVEF ANHLESKWVV LGTLLQEYGL
260 270 280 290 300
LQRRLENMEN LLKNRNFWIL RLPPGSNGEV PKVPVTFDDV AVHFSEQEWG
310 320 330 340 350
NLSEWQKELY KNVMRGNYES LVSMDYAISK PDLMSQMERG ERPTMQEQED
360 370 380 390 400
SEEGETPTDP SAAHDGIVIK IEVQTNDEGS ESLETPEPLM GQVEEHGFQD
410 420 430 440 450
SELGDPCGEQ PDLDMQEPEN TLEESTEGSS EFSELKQMLV QQRNCTEGIV
460 470 480 490 500
IKTEEQDEEE EEEEEDELPQ HLQSLGQLSG RYEASMYQTP LPGEMSPEGE
510 520 530 540 550
ESPPPLQLGN PAVKRLAPSV HGERHLSENR GASSQQQRNR RGERPFTCME
560 570 580 590 600
CGKSFRLKIN LIIHQRNHIK EGPYECAECE ISFRHKQQLT LHQRIHRVRG
610 620 630 640 650
GCVSPERGPT FNPKHALKPR PKSPSSGSGG GGPKPYKCPE CDSSFSHKSS
660 670 680 690 700
LTKHQITHTG ERPYTCPECK KSFRLHISLV IHQRVHAGKH EVSFICSLCG
710 720 730 740 750
KSFSRPSHLL RHQRTHTGER PFKCPECEKS FSEKSKLTNH CRVHSRERPH
760 770 780 790 800
ACPECGKSFI RKHHLLEHRR IHTGERPYHC AECGKRFTQK HHLLEHQRAH
810 820 830
TGERPYPCTH CAKCFRYKQS LKYHLRTHTG E
Length:831
Mass (Da):93,762
Last modified:May 8, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6AE3346E1A4EDF80
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH23985 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAA86599 differs from that shown. Contaminating sequence. Vector contamination at the C-terminus.Curated
The sequence BAA86599 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAC11033 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti446T → TA in BAC11033 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05745170R → W. Corresponds to variant dbSNP:rs3735318Ensembl.1
Natural variantiVAR_057452115V → A. Corresponds to variant dbSNP:rs3735319Ensembl.1
Natural variantiVAR_061965512A → T1 PublicationCorresponds to variant dbSNP:rs17852167Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC073314 Genomic DNA No translation available.
AB033111 mRNA Translation: BAA86599.1 Sequence problems.
BC023985 mRNA Translation: AAH23985.2 Different initiation.
AK074515 mRNA Translation: BAC11033.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43675.1

NCBI Reference Sequences

More...
RefSeqi
NP_056509.2, NM_015694.2
XP_011514357.1, XM_011516055.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000247930; ENSP00000247930; ENSG00000196453

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
27153

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:27153

UCSC genome browser

More...
UCSCi
uc003wfv.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073314 Genomic DNA No translation available.
AB033111 mRNA Translation: BAA86599.1 Sequence problems.
BC023985 mRNA Translation: AAH23985.2 Different initiation.
AK074515 mRNA Translation: BAC11033.1 Different initiation.
CCDSiCCDS43675.1
RefSeqiNP_056509.2, NM_015694.2
XP_011514357.1, XM_011516055.2

3D structure databases

SMRiQ9ULD5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi118035, 55 interactors
IntActiQ9ULD5, 19 interactors
STRINGi9606.ENSP00000247930

PTM databases

iPTMnetiQ9ULD5
PhosphoSitePlusiQ9ULD5

Polymorphism and mutation databases

BioMutaiZNF777
DMDMi152112417

Proteomic databases

EPDiQ9ULD5
jPOSTiQ9ULD5
MassIVEiQ9ULD5
PaxDbiQ9ULD5
PeptideAtlasiQ9ULD5
PRIDEiQ9ULD5

Genome annotation databases

EnsembliENST00000247930; ENSP00000247930; ENSG00000196453
GeneIDi27153
KEGGihsa:27153
UCSCiuc003wfv.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27153

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF777
HGNCiHGNC:22213 ZNF777
HPAiHPA003252
neXtProtiNX_Q9ULD5
OpenTargetsiENSG00000196453
PharmGKBiPA162410383

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000155153
HOGENOMiHOG000013125
InParanoidiQ9ULD5
KOiK09228
OMAiERGPAFN
OrthoDBi1318335at2759
PhylomeDBiQ9ULD5
TreeFamiTF337777

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
27153
PharosiQ9ULD5

Protein Ontology

More...
PROi
PR:Q9ULD5

Gene expression databases

BgeeiENSG00000196453 Expressed in 171 organ(s), highest expression level in endothelial cell
GenevisibleiQ9ULD5 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR022137 DUF3669_Znf
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF12417 DUF3669, 1 hit
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 8 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 9 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN777_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ULD5
Secondary accession number(s): Q8N2R2, Q8N659
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: May 8, 2019
Last modified: October 16, 2019
This is version 144 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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