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Entry version 184 (16 Oct 2019)
Sequence version 1 (01 May 2000)
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Protein

Ras-related protein Rab-23

Gene

RAB23

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi16 – 23GTPBy similarity8
Nucleotide bindingi64 – 68GTPBy similarity5
Nucleotide bindingi121 – 124GTPBy similarity4

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-8873719 RAB geranylgeranylation

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9ULC3

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q9ULC3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ras-related protein Rab-23
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RAB23
ORF Names:HSPC137
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14263 RAB23

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606144 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9ULC3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Cytoplasmic vesicle, Endosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Carpenter syndrome 1 (CRPT1)2 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA rare autosomal recessive disorder characterized by acrocephaly with variable synostosis of the sagittal, lambdoid, and coronal sutures; peculiar facies; brachydactyly of the hands with syndactyly; preaxial polydactyly and syndactyly of the feet; congenital heart defects; growth retardation; mental retardation; hypogenitalism; and obesity. In addition, cerebral malformations, oral and dental abnormalities, coxa valga, genu valgum, hydronephrosis, precocious puberty, and hearing loss may be observed.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06529412M → K in CRPT1. 1 Publication1
Natural variantiVAR_06529579Missing in CRPT1. 1 Publication1
Natural variantiVAR_03490285C → R in CRPT1. 1 Publication1

Keywords - Diseasei

Craniosynostosis, Disease mutation

Organism-specific databases

DisGeNET

More...
DisGeNETi
51715

MalaCards human disease database

More...
MalaCardsi
RAB23
MIMi201000 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000112210

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
65759 Carpenter syndrome

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34113

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9ULC3

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RAB23

Domain mapping of disease mutations (DMDM)

More...
DMDMi
12643897

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001212111 – 234Ras-related protein Rab-23Add BLAST234
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_0000370771235 – 237Removed in mature formSequence analysis3

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei186PhosphoserineCombined sources1
Modified residuei187PhosphoserineCombined sources1
Modified residuei234Cysteine methyl esterSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi234S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Methylation, Phosphoprotein, Prenylation

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9ULC3

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9ULC3

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q9ULC3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9ULC3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ULC3

PeptideAtlas

More...
PeptideAtlasi
Q9ULC3

PRoteomics IDEntifications database

More...
PRIDEi
Q9ULC3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
84975

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ULC3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ULC3

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9ULC3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000112210 Expressed in 202 organ(s), highest expression level in cauda epididymis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9ULC3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ULC3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA029135
HPA029136

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SUFU.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119694, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q9ULC3, 8 interactors

Molecular INTeraction database

More...
MINTi
Q9ULC3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000417610

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ULC3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi38 – 46Effector regionBy similarity9

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4252 Eukaryota
ENOG4110BDM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155064

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000233968

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ULC3

KEGG Orthology (KO)

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KOi
K06234

Identification of Orthologs from Complete Genome Data

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OMAi
IPTWKEK

Database of Orthologous Groups

More...
OrthoDBi
1340129at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ULC3

TreeFam database of animal gene trees

More...
TreeFami
TF317494

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04106 Rab23_like, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase
IPR034114 Rab23
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type

The PANTHER Classification System

More...
PANTHERi
PTHR24070 PTHR24070, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00071 Ras, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

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TIGRFAMsi
TIGR00231 small_GTP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51419 RAB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9ULC3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ
60 70 80 90 100
IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV
110 120 130 140 150
SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT
160 170 180 190 200
SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS
210 220 230
HSGQNSGTLN GGDVINLRPN KQRTKKNRNP FSSCSIP
Length:237
Mass (Da):26,659
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB9CB96E94DDF6036
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti95E → G in AAF29101 (PubMed:11042152).Curated1
Sequence conflicti144K → R in AAF29101 (PubMed:11042152).Curated1
Sequence conflicti225K → N in AAF29101 (PubMed:11042152).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_06529412M → K in CRPT1. 1 Publication1
Natural variantiVAR_03490013Missing 1 Publication1
Natural variantiVAR_03490140K → R1 PublicationCorresponds to variant dbSNP:rs45442500Ensembl.1
Natural variantiVAR_06529579Missing in CRPT1. 1 Publication1
Natural variantiVAR_03490285C → R in CRPT1. 1 Publication1
Natural variantiVAR_034903101S → A1 PublicationCorresponds to variant dbSNP:rs45479896EnsemblClinVar.1
Natural variantiVAR_017159207G → S2 PublicationsCorresponds to variant dbSNP:rs1040461EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB034244 mRNA Translation: BAA87324.1
AB025427 mRNA Translation: BAB40309.1
AF161486 mRNA Translation: AAF29101.1
AF498951 mRNA Translation: AAM21099.1
AK313796 mRNA Translation: BAG36532.1
AY585189 mRNA Translation: AAT79492.1
CR749371 mRNA Translation: CAH18224.1
AL031321 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX04476.1
BC015021 mRNA Translation: AAH15021.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4962.1

NCBI Reference Sequences

More...
RefSeqi
NP_001265595.1, NM_001278666.1
NP_001265596.1, NM_001278667.1
NP_001265597.1, NM_001278668.1
NP_057361.3, NM_016277.4
NP_899050.1, NM_183227.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000317483; ENSP00000320413; ENSG00000112210
ENST00000468148; ENSP00000417610; ENSG00000112210

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51715

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51715

UCSC genome browser

More...
UCSCi
uc003pds.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB034244 mRNA Translation: BAA87324.1
AB025427 mRNA Translation: BAB40309.1
AF161486 mRNA Translation: AAF29101.1
AF498951 mRNA Translation: AAM21099.1
AK313796 mRNA Translation: BAG36532.1
AY585189 mRNA Translation: AAT79492.1
CR749371 mRNA Translation: CAH18224.1
AL031321 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX04476.1
BC015021 mRNA Translation: AAH15021.1
CCDSiCCDS4962.1
RefSeqiNP_001265595.1, NM_001278666.1
NP_001265596.1, NM_001278667.1
NP_001265597.1, NM_001278668.1
NP_057361.3, NM_016277.4
NP_899050.1, NM_183227.2

3D structure databases

SMRiQ9ULC3
ModBaseiSearch...

Protein-protein interaction databases

BioGridi119694, 11 interactors
IntActiQ9ULC3, 8 interactors
MINTiQ9ULC3
STRINGi9606.ENSP00000417610

PTM databases

iPTMnetiQ9ULC3
PhosphoSitePlusiQ9ULC3
SwissPalmiQ9ULC3

Polymorphism and mutation databases

BioMutaiRAB23
DMDMi12643897

Proteomic databases

EPDiQ9ULC3
jPOSTiQ9ULC3
MassIVEiQ9ULC3
MaxQBiQ9ULC3
PaxDbiQ9ULC3
PeptideAtlasiQ9ULC3
PRIDEiQ9ULC3
ProteomicsDBi84975

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51715

Genome annotation databases

EnsembliENST00000317483; ENSP00000320413; ENSG00000112210
ENST00000468148; ENSP00000417610; ENSG00000112210
GeneIDi51715
KEGGihsa:51715
UCSCiuc003pds.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51715
DisGeNETi51715

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RAB23
HGNCiHGNC:14263 RAB23
HPAiHPA029135
HPA029136
MalaCardsiRAB23
MIMi201000 phenotype
606144 gene
neXtProtiNX_Q9ULC3
OpenTargetsiENSG00000112210
Orphaneti65759 Carpenter syndrome
PharmGKBiPA34113

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4252 Eukaryota
ENOG4110BDM LUCA
GeneTreeiENSGT00940000155064
HOGENOMiHOG000233968
InParanoidiQ9ULC3
KOiK06234
OMAiIPTWKEK
OrthoDBi1340129at2759
PhylomeDBiQ9ULC3
TreeFamiTF317494

Enzyme and pathway databases

ReactomeiR-HSA-8873719 RAB geranylgeranylation
SignaLinkiQ9ULC3
SIGNORiQ9ULC3

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RAB23 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RAB23

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51715
PharosiQ9ULC3

Protein Ontology

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PROi
PR:Q9ULC3

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000112210 Expressed in 202 organ(s), highest expression level in cauda epididymis
ExpressionAtlasiQ9ULC3 baseline and differential
GenevisibleiQ9ULC3 HS

Family and domain databases

CDDicd04106 Rab23_like, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR034114 Rab23
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type
PANTHERiPTHR24070 PTHR24070, 1 hit
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRAB23_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ULC3
Secondary accession number(s): B2R9I5
, Q68DJ6, Q8NI06, Q9P023
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 1, 2000
Last modified: October 16, 2019
This is version 184 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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