Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 166 (11 Dec 2019)
Sequence version 2 (18 May 2010)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Zinc finger protein 214

Gene

ZNF214

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri275 – 297C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri303 – 325C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 214
Alternative name(s):
BWSCR2-associated zinc finger protein 1
Short name:
BAZ-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF214
Synonyms:BAZ1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000149050.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13006 ZNF214

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605015 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UL59

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7761

Open Targets

More...
OpenTargetsi
ENSG00000149050

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37585

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UL59 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF214

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296453038

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000474581 – 606Zinc finger protein 214Add BLAST606

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UL59

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UL59

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UL59

PeptideAtlas

More...
PeptideAtlasi
Q9UL59

PRoteomics IDEntifications database

More...
PRIDEi
Q9UL59

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
84957

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UL59

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UL59

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000149050 Expressed in 118 organ(s), highest expression level in buccal mucosa cell

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UL59 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA055391

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113544, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UL59, 12 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000278314

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9UL59 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UL59

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 83KRABPROSITE-ProRule annotationAdd BLAST81

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri275 – 297C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri303 – 325C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163179

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UL59

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
YYKGFDQ

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UL59

TreeFam database of animal gene trees

More...
TreeFami
TF350845

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UL59-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVTFEDVTI IFTWEEWKFL DSSQKRLYRE VMWENYTNVM SVENWNESYK
60 70 80 90 100
SQEEKFRYLE YENFSYWQGW WNAGAQMYEN QNYGETVQGT DSKDLTQQDR
110 120 130 140 150
SQCQEWLILS TQVPGYGNYE LTFESKSLRN LKYKNFMPWQ SLETKTTQDY
160 170 180 190 200
GREIYMSGSH GFQGGRYRLG ISRKNLSMEK EQKLIVQHSY IPVEEALPQY
210 220 230 240 250
VGVICQEDLL RDSMEEKYCG CNKCKGIYYW NSRCVFHKRN QPGENLCQCS
260 270 280 290 300
ICKACFSQRS DLYRHPRNHI GKKLYGCDEV DGNFHQSSGV HFHQRVHIGE
310 320 330 340 350
VPYSCNACGK SFSQISSLHN HQRVHTEEKF YKIECDKDLS RNSLLHIHQR
360 370 380 390 400
LHIGEKPFKC NQCGKSFNRS SVLHVHQRVH TGEKPYKCDE CGKGFSQSSN
410 420 430 440 450
LRIHQLVHTG EKSYKCEDCG KGFTQRSNLQ IHQRVHTGEK PYKCDDCGKD
460 470 480 490 500
FSHSSDLRIH QRVHTGEKPY TCPECGKGFS KSSKLHTHQR VHTGEKPYKC
510 520 530 540 550
EECGKGFSQR SHLLIHQRVH TGEKPYKCHD CGKGFSHSSN LHIHQRVHTG
560 570 580 590 600
EKPYQCAKCG KGFSHSSALR IHQRVHAGEK PYKCREYYKG FDHNSHLHNN

HRRGNL
Length:606
Mass (Da):70,992
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD0CBA2E0F9E3EAB2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti252C → R in AAF00004 (PubMed:10762538).Curated1
Sequence conflicti252C → R in BAG36248 (PubMed:14702039).Curated1
Sequence conflicti252C → R in AAI36773 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05740366Y → C. Corresponds to variant dbSNP:rs1156526Ensembl.1
Natural variantiVAR_019975128L → H. Corresponds to variant dbSNP:rs1156525Ensembl.1
Natural variantiVAR_057404160H → R. Corresponds to variant dbSNP:rs16921097Ensembl.1
Natural variantiVAR_019976185I → R. Corresponds to variant dbSNP:rs2239734Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF056617 mRNA Translation: AAF00004.1
AK313462 mRNA Translation: BAG36248.1
AC100875 Genomic DNA No translation available.
BC136772 mRNA Translation: AAI36773.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS31418.1

NCBI Reference Sequences

More...
RefSeqi
NP_037381.2, NM_013249.2
XP_005253185.1, XM_005253128.3
XP_006718371.1, XM_006718308.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000278314; ENSP00000278314; ENSG00000149050
ENST00000536068; ENSP00000445373; ENSG00000149050

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7761

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7761

UCSC genome browser

More...
UCSCi
uc001mfa.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF056617 mRNA Translation: AAF00004.1
AK313462 mRNA Translation: BAG36248.1
AC100875 Genomic DNA No translation available.
BC136772 mRNA Translation: AAI36773.1
CCDSiCCDS31418.1
RefSeqiNP_037381.2, NM_013249.2
XP_005253185.1, XM_005253128.3
XP_006718371.1, XM_006718308.3

3D structure databases

SMRiQ9UL59
ModBaseiSearch...

Protein-protein interaction databases

BioGridi113544, 15 interactors
IntActiQ9UL59, 12 interactors
STRINGi9606.ENSP00000278314

PTM databases

iPTMnetiQ9UL59
PhosphoSitePlusiQ9UL59

Polymorphism and mutation databases

BioMutaiZNF214
DMDMi296453038

Proteomic databases

jPOSTiQ9UL59
MassIVEiQ9UL59
PaxDbiQ9UL59
PeptideAtlasiQ9UL59
PRIDEiQ9UL59
ProteomicsDBi84957

Genome annotation databases

EnsembliENST00000278314; ENSP00000278314; ENSG00000149050
ENST00000536068; ENSP00000445373; ENSG00000149050
GeneIDi7761
KEGGihsa:7761
UCSCiuc001mfa.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7761
DisGeNETi7761
EuPathDBiHostDB:ENSG00000149050.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF214
HGNCiHGNC:13006 ZNF214
HPAiHPA055391
MIMi605015 gene
neXtProtiNX_Q9UL59
OpenTargetsiENSG00000149050
PharmGKBiPA37585

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163179
HOGENOMiHOG000234617
InParanoidiQ9UL59
KOiK09228
OMAiYYKGFDQ
OrthoDBi1318335at2759
PhylomeDBiQ9UL59
TreeFamiTF350845

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7761
PharosiQ9UL59 Tdark

Protein Ontology

More...
PROi
PR:Q9UL59
RNActiQ9UL59 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000149050 Expressed in 118 organ(s), highest expression level in buccal mucosa cell
GenevisibleiQ9UL59 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 9 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN214_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UL59
Secondary accession number(s): B2R8Q1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 18, 2010
Last modified: December 11, 2019
This is version 166 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again