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Protein

Paraneoplastic antigen Ma2

Gene

PNMA2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Antibodies against PNMA2 are present in sera from patients suffering of paraneoplastic neurological disorders.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTumor antigen

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Paraneoplastic antigen Ma2
Alternative name(s):
40 kDa neuronal protein
Onconeuronal antigen Ma2
Paraneoplastic neuronal antigen MM2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PNMA2
Synonyms:KIAA0883, MA2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000240694.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9159 PNMA2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
603970 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UL42

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10687

Open Targets

More...
OpenTargetsi
ENSG00000240694

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33482

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PNMA2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
37999812

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001552022 – 364Paraneoplastic antigen Ma2Add BLAST363

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UL42

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UL42

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UL42

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UL42

PeptideAtlas

More...
PeptideAtlasi
Q9UL42

PRoteomics IDEntifications database

More...
PRIDEi
Q9UL42

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84944

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UL42

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UL42

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Brain-specific. In some cancer patients, specifically expressed by testicular tumor cells.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000240694 Expressed in 175 organ(s), highest expression level in postcentral gyrus

CleanEx database of gene expression profiles

More...
CleanExi
HS_PNMA2

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UL42 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA001936

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115926, 50 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UL42, 45 interactors

Molecular INTeraction database

More...
MINTi
Q9UL42

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000429344

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UL42

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UL42

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi333 – 338Poly-Glu6

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PNMA family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J6QQ Eukaryota
ENOG410Y05Y LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153794

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000013079

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG052488

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UL42

Identification of Orthologs from Complete Genome Data

More...
OMAi
FKTPNQD

Database of Orthologous Groups

More...
OrthoDBi
820525at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UL42

TreeFam database of animal gene trees

More...
TreeFami
TF335054

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026523 PNMA
IPR026525 PNMA2

The PANTHER Classification System

More...
PANTHERi
PTHR23095 PTHR23095, 1 hit
PTHR23095:SF16 PTHR23095:SF16, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14893 PNMA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9UL42-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALALLEDWC RIMSVDEQKS LMVTGIPADF EEAEIQEVLQ ETLKSLGRYR
60 70 80 90 100
LLGKIFRKQE NANAVLLELL EDTDVSAIPS EVQGKGGVWK VIFKTPNQDT
110 120 130 140 150
EFLERLNLFL EKEGQTVSGM FRALGQEGVS PATVPCISPE LLAHLLGQAM
160 170 180 190 200
AHAPQPLLPM RYRKLRVFSG SAVPAPEEES FEVWLEQATE IVKEWPVTEA
210 220 230 240 250
EKKRWLAESL RGPALDLMHI VQADNPSISV EECLEAFKQV FGSLESRRTA
260 270 280 290 300
QVRYLKTYQE EGEKVSAYVL RLETLLRRAV EKRAIPRRIA DQVRLEQVMA
310 320 330 340 350
GATLNQMLWC RLRELKDQGP PPSFLELMKV IREEEEEEAS FENESIEEPE
360
ERDGYGRWNH EGDD
Length:364
Mass (Da):41,509
Last modified:October 24, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E417AD96E3F0E93
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA74906 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti128 – 129GV → AL in AAD02098 (PubMed:10362822).Curated2
Sequence conflicti141L → I in AAD02098 (PubMed:10362822).Curated1
Sequence conflicti257T → P in AAF05625 (PubMed:10362822).Curated1
Sequence conflicti278R → K in AAF05626 (PubMed:10362822).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_053597186E → K. Corresponds to variant dbSNP:rs2233701Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF037365 mRNA Translation: AAD02098.1
AF083114 mRNA Translation: AAF05625.1
AF083115 mRNA Translation: AAF05626.1
AF286487 mRNA Translation: AAG28165.1
AB020690 mRNA Translation: BAA74906.2 Different initiation.
AK055325 mRNA Translation: BAG51501.1
CH471080 Genomic DNA Translation: EAW63575.1
BC047515 mRNA Translation: AAH47515.1
BC062301 mRNA Translation: AAH62301.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34868.1

NCBI Reference Sequences

More...
RefSeqi
NP_009188.1, NM_007257.5
XP_011542667.1, XM_011544365.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.591838

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000522362; ENSP00000429344; ENSG00000240694

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10687

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10687

UCSC genome browser

More...
UCSCi
uc003xez.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF037365 mRNA Translation: AAD02098.1
AF083114 mRNA Translation: AAF05625.1
AF083115 mRNA Translation: AAF05626.1
AF286487 mRNA Translation: AAG28165.1
AB020690 mRNA Translation: BAA74906.2 Different initiation.
AK055325 mRNA Translation: BAG51501.1
CH471080 Genomic DNA Translation: EAW63575.1
BC047515 mRNA Translation: AAH47515.1
BC062301 mRNA Translation: AAH62301.1
CCDSiCCDS34868.1
RefSeqiNP_009188.1, NM_007257.5
XP_011542667.1, XM_011544365.2
UniGeneiHs.591838

3D structure databases

ProteinModelPortaliQ9UL42
SMRiQ9UL42
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115926, 50 interactors
IntActiQ9UL42, 45 interactors
MINTiQ9UL42
STRINGi9606.ENSP00000429344

PTM databases

iPTMnetiQ9UL42
PhosphoSitePlusiQ9UL42

Polymorphism and mutation databases

BioMutaiPNMA2
DMDMi37999812

Proteomic databases

EPDiQ9UL42
jPOSTiQ9UL42
MaxQBiQ9UL42
PaxDbiQ9UL42
PeptideAtlasiQ9UL42
PRIDEiQ9UL42
ProteomicsDBi84944

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10687
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000522362; ENSP00000429344; ENSG00000240694
GeneIDi10687
KEGGihsa:10687
UCSCiuc003xez.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10687
DisGeNETi10687
EuPathDBiHostDB:ENSG00000240694.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PNMA2
HGNCiHGNC:9159 PNMA2
HPAiHPA001936
MIMi603970 gene
neXtProtiNX_Q9UL42
OpenTargetsiENSG00000240694
PharmGKBiPA33482

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410J6QQ Eukaryota
ENOG410Y05Y LUCA
GeneTreeiENSGT00940000153794
HOGENOMiHOG000013079
HOVERGENiHBG052488
InParanoidiQ9UL42
OMAiFKTPNQD
OrthoDBi820525at2759
PhylomeDBiQ9UL42
TreeFamiTF335054

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PNMA2 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
PNMA2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10687

Protein Ontology

More...
PROi
PR:Q9UL42

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000240694 Expressed in 175 organ(s), highest expression level in postcentral gyrus
CleanExiHS_PNMA2
GenevisibleiQ9UL42 HS

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
IPR026525 PNMA2
PANTHERiPTHR23095 PTHR23095, 1 hit
PTHR23095:SF16 PTHR23095:SF16, 1 hit
PfamiView protein in Pfam
PF14893 PNMA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPNMA2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UL42
Secondary accession number(s): B3KNY9
, O94959, O95145, Q49A18, Q9UL43
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: October 24, 2003
Last modified: January 16, 2019
This is version 142 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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