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Protein

Mucin-12

Gene

MUC12

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium.1 Publication

Miscellaneous

Infection by L.monocytogenes induces increases in mucin secretion and MUC4 and MUC12 transcription. This may constitute a host cell defense response that inhibits the entry of listeria monocytogenes in the cell.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5083625 Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
R-HSA-5083632 Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
R-HSA-5083636 Defective GALNT12 causes colorectal cancer 1 (CRCS1)
R-HSA-5621480 Dectin-2 family
R-HSA-913709 O-linked glycosylation of mucins
R-HSA-977068 Termination of O-glycan biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mucin-12
Short name:
MUC-12
Alternative name(s):
Mucin-11
Short name:
MUC-11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MUC12
Synonyms:MUC11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000205277.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7510 MUC12

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604609 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UKN1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini17 – 5380ExtracellularSequence analysisAdd BLAST5364
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei5381 – 5401HelicalSequence analysisAdd BLAST21
Topological domaini5402 – 5478CytoplasmicSequence analysisAdd BLAST77

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10071

Open Targets

More...
OpenTargetsi
ENSG00000205277

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MUC12

Domain mapping of disease mutations (DMDM)

More...
DMDMi
187609692

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 16Sequence analysisAdd BLAST16
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000033162017 – 5478Mucin-12Add BLAST5462

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi154N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi170N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi176N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi382N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi738N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1793N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi3350N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4433N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi4571N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi5144 ↔ 5153By similarity
Glycosylationi5169N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi5182N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi5197N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi5228N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi5264N-linked (GlcNAc...) asparagineSequence analysis1

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei5229 – 5230CleavageBy similarity2

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UKN1

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9UKN1

PeptideAtlas

More...
PeptideAtlasi
Q9UKN1

PRoteomics IDEntifications database

More...
PRIDEi
Q9UKN1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84823

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UKN1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UKN1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous, with higher expression in colon. Down-regulated in colorectal cancer as well as in the colon of patients with ulcerative colitis (UC) and Crohn's disease (CD).2 Publications

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By listeriolysin O.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000205277 Expressed in 94 organ(s), highest expression level in mucosa of sigmoid colon

CleanEx database of gene expression profiles

More...
CleanExi
HS_MUC12

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UKN1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UKN1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA023835

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
115382, 2 interactors

Protein interaction database and analysis system

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IntActi
Q9UKN1, 2 interactors

STRING: functional protein association networks

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STRINGi
9606.ENSP00000441929

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q9UKN1

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati222 – 2401Add BLAST19
Repeati471 – 4892Add BLAST19
Repeati499 – 5173Add BLAST19
Repeati662 – 6804Add BLAST19
Repeati827 – 8455Add BLAST19
Repeati1159 – 11776Add BLAST19
Repeati1466 – 14847Add BLAST19
Repeati1633 – 16518Add BLAST19
Repeati1717 – 17359Add BLAST19
Repeati1882 – 190010Add BLAST19
Repeati1910 – 192811Add BLAST19
Repeati2075 – 209312Add BLAST19
Repeati2242 – 226013Add BLAST19
Repeati2549 – 256714Add BLAST19
Repeati2716 – 273415Add BLAST19
Repeati3023 – 304116Add BLAST19
Repeati3190 – 320817Add BLAST19
Repeati3274 – 329218Add BLAST19
Repeati3439 – 345719Add BLAST19
Repeati3467 – 348520Add BLAST19
Repeati3632 – 365021Add BLAST19
Repeati3799 – 381722Add BLAST19
Repeati4106 – 412423Add BLAST19
Repeati4273 – 429124Add BLAST19
Repeati4522 – 454025Add BLAST19
Repeati4550 – 456826Add BLAST19
Repeati4715 – 473327Add BLAST19
Repeati4743 – 476128Add BLAST19
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5116 – 5154EGF-likeAdd BLAST39
Domaini5168 – 5275SEAPROSITE-ProRule annotationAdd BLAST108

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni222 – 476128 X 19 AA approximate tandem repeats of E-E-S-X-X-X-H-X-X-P-X-X-T-X-T-X-X-X-PAdd BLAST4540

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi5226 – 5233Cleavage motifBy similarity8

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi156 – 5021Ser-richAdd BLAST4866

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The proteolytic cleavage occurs within the SEA domain. This domain is not interchangeable, suggesting that it is insufficient to mediate efficient cleavage.1 Publication

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IK1M Eukaryota
ENOG41126RR LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000165469

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG099234

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9UKN1

KEGG Orthology (KO)

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KOi
K22018

Identification of Orthologs from Complete Genome Data

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OMAi
AIASTHD

Database of Orthologous Groups

More...
OrthoDBi
44585at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UKN1

TreeFam database of animal gene trees

More...
TreeFami
TF344108

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013032 EGF-like_CS
IPR000082 SEA_dom
IPR036364 SEA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01390 SEA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF82671 SSF82671, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS50024 SEA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UKN1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLVIWILTLA LRLCASVTTV TPEGSAVHKA ISQQGTLWTG EVLEKQTVEQ
60 70 80 90 100
GKSTLRRQKN HFHRSAGELR CRNALKDEGA SAGWSVMFAG ESVVVLVHLW
110 120 130 140 150
MTGARVKNLG LVEFASPGDD GDGRAEGFSL GLPLSEQARA AGAREKERQE
160 170 180 190 200
TVINHSTFSG FSQITGSTVN TSIGGNTTSA STPSSSDPFT TFSDYGVSVT
210 220 230 240 250
FITGSTATKH FLDSSTNSGH SEESTVSHSG PGATGTTLFP SHSATSVFVG
260 270 280 290 300
EPKTSPITSA SMETTALPGS TTTAGLSEKS TTFYSSPRSP DRTLSPARTT
310 320 330 340 350
SSGVSEKSTT SHSRPGPTHT IAFPDSTTMP GVSQESTASH SIPGSTDTTL
360 370 380 390 400
SPGTTTPSSL GPESTTFHSS PGYTKTTRLP DNTTTSGLLE ASTPVHSSTG
410 420 430 440 450
SPHTTLSPSS STTHEGEPTT FQSWPSSKDT SPAPSGTTSA FVKLSTTYHS
460 470 480 490 500
SPSSTPTTHF SASSTTLGHS EESTPVHSSP VATATTPPPA RSATSGHVEE
510 520 530 540 550
STAYHRSPGS TQTMHFPESS TTSGHSEESA TFHGSTTHTK SSTPSTTAAL
560 570 580 590 600
AHTSYHSSLG STETTHFRDS STISGRSEES KASHSSPDAM ATTVLPAGST
610 620 630 640 650
PSVLVGDSTP SPISSGSMET TALPGSTTKP GLSEKSTTFY SSPRSPDTTH
660 670 680 690 700
LPASMTSSGV SEESTTSHSR PGSTHTTAFP GSTTMPGLSQ ESTASHSSPG
710 720 730 740 750
PTDTTLSPGS TTASSLGPEY TTFHSRPGST ETTLLPDNTT ASGLLEASMP
760 770 780 790 800
VHSSTRSPHT TLSPAGSTTR QGESTTFHSW PSSKDTRPAP PTTTSAFVEP
810 820 830 840 850
STTSHGSPSS IPTTHISARS TTSGLVEEST TYHSSPGSTQ TMHFPESDTT
860 870 880 890 900
SGRGEESTTS HSSTTHTISS APSTTSALVE EPTSYHSSPG STATTHFPDS
910 920 930 940 950
STTSGRSEES TASHSSQDAT GTIVLPARST TSVLLGESTT SPISSGSMET
960 970 980 990 1000
TALPGSTTTP GLSERSTTFH SSPRSPATTL SPASTTSSGV SEESTTSRSR
1010 1020 1030 1040 1050
PGSTHTTAFP DSTTTPGLSR HSTTSHSSPG STDTTLLPAS TTTSGPSQES
1060 1070 1080 1090 1100
TTSHSSSGST DTALSPGSTT ALSFGQESTT FHSNPGSTHT TLFPDSTTSS
1110 1120 1130 1140 1150
GIVEASTRVH SSTGSPRTTL SPASSTSPGL QGESTAFQTH PASTHTTPSP
1160 1170 1180 1190 1200
PSTATAPVEE STTYHRSPGS TPTTHFPASS TTSGHSEKST IFHSSPDASG
1210 1220 1230 1240 1250
TTPSSAHSTT SGRGESTTSR ISPGSTEITT LPGSTTTPGL SEASTTFYSS
1260 1270 1280 1290 1300
PRSPTTTLSP ASMTSLGVGE ESTTSRSQPG STHSTVSPAS TTTPGLSEES
1310 1320 1330 1340 1350
TTVYSSSRGS TETTVFPHST TTSVHGEEPT TFHSRPASTH TTLFTEDSTT
1360 1370 1380 1390 1400
SGLTEESTAF PGSPASTQTG LPATLTTADL GEESTTFPSS SGSTGTKLSP
1410 1420 1430 1440 1450
ARSTTSGLVG ESTPSRLSPS STETTTLPGS PTTPSLSEKS TTFYTSPRSP
1460 1470 1480 1490 1500
DATLSPATTT SSGVSEESST SHSQPGSTHT TAFPDSTTTS DLSQEPTTSH
1510 1520 1530 1540 1550
SSQGSTEATL SPGSTTASSL GQQSTTFHSS PGDTETTLLP DDTITSGLVE
1560 1570 1580 1590 1600
ASTPTHSSTG SLHTTLTPAS STSAGLQEES TTFQSWPSSS DTTPSPPGTT
1610 1620 1630 1640 1650
AAPVEVSTTY HSRPSSTPTT HFSASSTTLG RSEESTTVHS SPGATGTALF
1660 1670 1680 1690 1700
PTRSATSVLV GEPTTSPISS GSTETTALPG STTTAGLSEK STTFYSSPRS
1710 1720 1730 1740 1750
PDTTLSPAST TSSGVSEEST TSHSRPGSTH TTAFPGSTTM PGVSQESTAS
1760 1770 1780 1790 1800
HSSPGSTDTT LSPGSTTASS LGPESTTFHS SPGSTETTLL PDNTTASGLL
1810 1820 1830 1840 1850
EASTPVHSST GSPHTTLSPA GSTTRQGEST TFQSWPSSKD TMPAPPTTTS
1860 1870 1880 1890 1900
AFVELSTTSH GSPSSTPTTH FSASSTTLGR SEESTTVHSS PVATATTPSP
1910 1920 1930 1940 1950
ARSTTSGLVE ESTAYHSSPG STQTMHFPES STASGRSEES RTSHSSTTHT
1960 1970 1980 1990 2000
ISSPPSTTSA LVEEPTSYHS SPGSTATTHF PDSSTTSGRS EESTASHSSQ
2010 2020 2030 2040 2050
DATGTIVLPA RSTTSVLLGE STTSPISSGS METTALPGST TTPGLSEKST
2060 2070 2080 2090 2100
TFHSSPRSPA TTLSPASTTS SGVSEESTTS HSRPGSTHTT AFPDSTTTPG
2110 2120 2130 2140 2150
LSRHSTTSHS SPGSTDTTLL PASTTTSGPS QESTTSHSSP GSTDTALSPG
2160 2170 2180 2190 2200
STTALSFGQE STTFHSSPGS THTTLFPDST TSSGIVEAST RVHSSTGSPR
2210 2220 2230 2240 2250
TTLSPASSTS PGLQGESTAF QTHPASTHTT PSPPSTATAP VEESTTYHRS
2260 2270 2280 2290 2300
PGSTPTTHFP ASSTTSGHSE KSTIFHSSPD ASGTTPSSAH STTSGRGEST
2310 2320 2330 2340 2350
TSRISPGSTE ITTLPGSTTT PGLSEASTTF YSSPRSPTTT LSPASMTSLG
2360 2370 2380 2390 2400
VGEESTTSRS QPGSTHSTVS PASTTTPGLS EESTTVYSSS PGSTETTVFP
2410 2420 2430 2440 2450
RTPTTSVRGE EPTTFHSRPA STHTTLFTED STTSGLTEES TAFPGSPAST
2460 2470 2480 2490 2500
QTGLPATLTT ADLGEESTTF PSSSGSTGTT LSPARSTTSG LVGESTPSRL
2510 2520 2530 2540 2550
SPSSTETTTL PGSPTTPSLS EKSTTFYTSP RSPDATLSPA TTTSSGVSEE
2560 2570 2580 2590 2600
SSTSHSQPGS THTTAFPDST TTPGLSRHST TSHSSPGSTD TTLLPASTTT
2610 2620 2630 2640 2650
SGPSQESTTS HSSPGSTDTA LSPGSTTALS FGQESTTFHS SPGSTHTTLF
2660 2670 2680 2690 2700
PDSTTSSGIV EASTRVHSST GSPRTTLSPA SSTSPGLQGE STTFQTHPAS
2710 2720 2730 2740 2750
THTTPSPPST ATAPVEESTT YHRSPGSTPT THFPASSTTS GHSEKSTIFH
2760 2770 2780 2790 2800
SSPDASGTTP SSAHSTTSGR GESTTSRISP GSTEITTLPG STTTPGLSEA
2810 2820 2830 2840 2850
STTFYSSPRS PTTTLSPASM TSLGVGEEST TSRSQPGSTH STVSPASTTT
2860 2870 2880 2890 2900
PGLSEESTTV YSSSPGSTET TVFPRSTTTS VRGEEPTTFH SRPASTHTTL
2910 2920 2930 2940 2950
FTEDSTTSGL TEESTAFPGS PASTQTGLPA TLTTADLGEE STTFPSSSGS
2960 2970 2980 2990 3000
TGTTLSPARS TTSGLVGEST PSRLSPSSTE TTTLPGSPTT PSLSEKSTTF
3010 3020 3030 3040 3050
YTSPRSPDAT LSPATTTSSG VSEESSTSHS QPGSTHTTAF PDSTTTSGLS
3060 3070 3080 3090 3100
QEPTASHSSQ GSTEATLSPG STTASSLGQQ STTFHSSPGD TETTLLPDDT
3110 3120 3130 3140 3150
ITSGLVEAST PTHSSTGSLH TTLTPASSTS AGLQEESTTF QSWPSSSDTT
3160 3170 3180 3190 3200
PSPPGTTAAP VEVSTTYHSR PSSTPTTHFS ASSTTLGRSE ESTTVHSSPG
3210 3220 3230 3240 3250
ATGTALFPTR SATSVLVGEP TTSPISSGST ETTALPGSTT TAGLSEKSTT
3260 3270 3280 3290 3300
FYSSPRSPDT TLSPASTTSS GVSEESTTSH SRPGSTHTTA FPGSTTMPGV
3310 3320 3330 3340 3350
SQESTASHSS PGSTDTTLSP GSTTASSLGP ESTTFHSGPG STETTLLPDN
3360 3370 3380 3390 3400
TTASGLLEAS TPVHSSTGSP HTTLSPAGST TRQGESTTFQ SWPNSKDTTP
3410 3420 3430 3440 3450
APPTTTSAFV ELSTTSHGSP SSTPTTHFSA SSTTLGRSEE STTVHSSPVA
3460 3470 3480 3490 3500
TATTPSPARS TTSGLVEEST TYHSSPGSTQ TMHFPESDTT SGRGEESTTS
3510 3520 3530 3540 3550
HSSTTHTISS APSTTSALVE EPTSYHSSPG STATTHFPDS STTSGRSEES
3560 3570 3580 3590 3600
TASHSSQDAT GTIVLPARST TSVLLGESTT SPISSGSMET TALPGSTTTP
3610 3620 3630 3640 3650
GLSEKSTTFH SSPRSPATTL SPASTTSSGV SEESTTSHSR PGSTHTTAFP
3660 3670 3680 3690 3700
DSTTTPGLSR HSTTSHSSPG STDTTLLPAS TTTSGSSQES TTSHSSSGST
3710 3720 3730 3740 3750
DTALSPGSTT ALSFGQESTT FHSSPGSTHT TLFPDSTTSS GIVEASTRVH
3760 3770 3780 3790 3800
SSTGSPRTTL SPASSTSPGL QGESTAFQTH PASTHTTPSP PSTATAPVEE
3810 3820 3830 3840 3850
STTYHRSPGS TPTTHFPASS TTSGHSEKST IFHSSPDASG TTPSSAHSTT
3860 3870 3880 3890 3900
SGRGESTTSR ISPGSTEITT LPGSTTTPGL SEASTTFYSS PRSPTTTLSP
3910 3920 3930 3940 3950
ASMTSLGVGE ESTTSRSQPG STHSTVSPAS TTTPGLSEES TTVYSSSPGS
3960 3970 3980 3990 4000
TETTVFPRST TTSVRREEPT TFHSRPASTH TTLFTEDSTT SGLTEESTAF
4010 4020 4030 4040 4050
PGSPASTQTG LPATLTTADL GEESTTFPSS SGSTGTKLSP ARSTTSGLVG
4060 4070 4080 4090 4100
ESTPSRLSPS STETTTLPGS PTTPSLSEKS TTFYTSPRSP DATLSPATTT
4110 4120 4130 4140 4150
SSGVSEESST SHSQPGSTHT TAFPDSTTTS GLSQEPTTSH SSQGSTEATL
4160 4170 4180 4190 4200
SPGSTTASSL GQQSTTFHSS PGDTETTLLP DDTITSGLVE ASTPTHSSTG
4210 4220 4230 4240 4250
SLHTTLTPAS STSTGLQEES TTFQSWPSSS DTTPSPPSTT AVPVEVSTTY
4260 4270 4280 4290 4300
HSRPSSTPTT HFSASSTTLG RSEESTTVHS SPGATGTALF PTRSATSVLV
4310 4320 4330 4340 4350
GEPTTSPISS GSTETTALPG STTTAGLSEK STTFYSSPRS PDTTLSPAST
4360 4370 4380 4390 4400
TSSGVSEEST TSHSRPGSMH TTAFPSSTTM PGVSQESTAS HSSPGSTDTT
4410 4420 4430 4440 4450
LSPGSTTASS LGPESTTFHS SPGSTETTLL PDNTTASGLL EASTPVHSST
4460 4470 4480 4490 4500
GSPHTTLSPA GSTTRQGEST TFQSWPNSKD TTPAPPTTTS AFVELSTTSH
4510 4520 4530 4540 4550
GSPSSTPTTH FSASSTTLGR SEESTTVHSS PVATATTPSP ARSTTSGLVE
4560 4570 4580 4590 4600
ESTTYHSSPG STQTMHFPES NTTSGRGEES TTSHSSTTHT ISSAPSTTSA
4610 4620 4630 4640 4650
LVEEPTSYHS SPGSTATTHF PDSSTTSGRS EESTASHSSQ DATGTIVLPA
4660 4670 4680 4690 4700
RSTTSVLLGE STTSPISSGS METTALPGST TTPGLSEKST TFHSSPSSTP
4710 4720 4730 4740 4750
TTHFSASSTT LGRSEESTTV HSSPVATATT PSPARSTTSG LVEESTAYHS
4760 4770 4780 4790 4800
SPGSTQTMHF PESSTASGRS EESRTSHSST THTISSPPST TSALVEEPTS
4810 4820 4830 4840 4850
YHSSPGSIAT THFPESSTTS GRSEESTASH SSPDTNGITP LPAHFTTSGR
4860 4870 4880 4890 4900
IAESTTFYIS PGSMETTLAS TATTPGLSAK STILYSSSRS PDQTLSPASM
4910 4920 4930 4940 4950
TSSSISGEPT SLYSQAESTH TTAFPASTTT SGLSQESTTF HSKPGSTETT
4960 4970 4980 4990 5000
LSPGSITTSS FAQEFTTPHS QPGSALSTVS PASTTVPGLS EESTTFYSSP
5010 5020 5030 5040 5050
GSTETTAFSH SNTMSIHSQQ STPFPDSPGF THTVLPATLT TTDIGQESTA
5060 5070 5080 5090 5100
FHSSSDATGT TPLPARSTAS DLVGEPTTFY ISPSPTYTTL FPASSSTSGL
5110 5120 5130 5140 5150
TEESTTFHTS PSFTSTIVST ESLETLAPGL CQEGQIWNGK QCVCPQGYVG
5160 5170 5180 5190 5200
YQCLSPLESF PVETPEKLNA TLGMTVKVTY RNFTEKMNDA SSQEYQNFST
5210 5220 5230 5240 5250
LFKNRMDVVL KGDNLPQYRG VNIRRLLNGS IVVKNDVILE ADYTLEYEEL
5260 5270 5280 5290 5300
FENLAEIVKA KIMNETRTTL LDPDSCRKAI LCYSEEDTFV DSSVTPGFDF
5310 5320 5330 5340 5350
QEQCTQKAAE GYTQFYYVDV LDGKLACVNK CTKGTKSQMN CNLGTCQLQR
5360 5370 5380 5390 5400
SGPRCLCPNT NTHWYWGETC EFNIAKSLVY GIVGAVMAVL LLALIILIIL
5410 5420 5430 5440 5450
FSLSQRKRHR EQYDVPQEWR KEGTPGIFQK TAIWEDQNLR ESRFGLENAY
5460 5470
NNFRPTLETV DSGTELHIQR PEMVASTV
Note: No experimental confirmation available.
Length:5,478
Mass (Da):558,164
Last modified:April 29, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6157CF28FEDDA0E5
GO
Isoform 2 (identifier: Q9UKN1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     23-165: Missing.

Note: No experimental confirmation available.
Show »
Length:5,335
Mass (Da):542,703
Checksum:iCD7AB1285CD3E1BE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7BXN1H7BXN1_HUMAN
Mucin-12
MUC12
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti3283 – 3286PGST → RNRP in AAD55679 (PubMed:10463611).Curated4
Sequence conflicti3556S → N in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti3686S → P in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti3697S → P in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti3790P → T in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti3809G → S in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti3966R → G in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti4037K → T in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti4137T → K in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti4214T → A in AAD55679 (PubMed:10463611).Curated1
Sequence conflicti4238 – 4239ST → GP in AAD55679 (PubMed:10463611).Curated2
Sequence conflicti4901T → R in AAD55678 (PubMed:10463611).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0429064775T → R. Corresponds to variant dbSNP:rs11766125Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_05672123 – 165Missing in isoform 2. CuratedAdd BLAST143

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC105446 Genomic DNA No translation available.
AF147790 mRNA Translation: AAD55678.1
AF147791 mRNA Translation: AAD55679.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS55139.1 [Q9UKN1-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001157934.1, NM_001164462.1 [Q9UKN1-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.489355

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000379442; ENSP00000368755; ENSG00000205277 [Q9UKN1-1]
ENST00000536621; ENSP00000441929; ENSG00000205277 [Q9UKN1-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10071

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10071

UCSC genome browser

More...
UCSCi
uc003uxo.4 human [Q9UKN1-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Mucin database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105446 Genomic DNA No translation available.
AF147790 mRNA Translation: AAD55678.1
AF147791 mRNA Translation: AAD55679.1
CCDSiCCDS55139.1 [Q9UKN1-2]
RefSeqiNP_001157934.1, NM_001164462.1 [Q9UKN1-2]
UniGeneiHs.489355

3D structure databases

ProteinModelPortaliQ9UKN1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115382, 2 interactors
IntActiQ9UKN1, 2 interactors
STRINGi9606.ENSP00000441929

PTM databases

iPTMnetiQ9UKN1
PhosphoSitePlusiQ9UKN1

Polymorphism and mutation databases

BioMutaiMUC12
DMDMi187609692

Proteomic databases

jPOSTiQ9UKN1
PaxDbiQ9UKN1
PeptideAtlasiQ9UKN1
PRIDEiQ9UKN1
ProteomicsDBi84823

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379442; ENSP00000368755; ENSG00000205277 [Q9UKN1-1]
ENST00000536621; ENSP00000441929; ENSG00000205277 [Q9UKN1-2]
GeneIDi10071
KEGGihsa:10071
UCSCiuc003uxo.4 human [Q9UKN1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10071
DisGeNETi10071
EuPathDBiHostDB:ENSG00000205277.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MUC12

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0201128
HGNCiHGNC:7510 MUC12
HPAiHPA023835
MIMi604609 gene
neXtProtiNX_Q9UKN1
OpenTargetsiENSG00000205277

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IK1M Eukaryota
ENOG41126RR LUCA
GeneTreeiENSGT00940000165469
HOVERGENiHBG099234
InParanoidiQ9UKN1
KOiK22018
OMAiAIASTHD
OrthoDBi44585at2759
PhylomeDBiQ9UKN1
TreeFamiTF344108

Enzyme and pathway databases

ReactomeiR-HSA-5083625 Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
R-HSA-5083632 Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
R-HSA-5083636 Defective GALNT12 causes colorectal cancer 1 (CRCS1)
R-HSA-5621480 Dectin-2 family
R-HSA-913709 O-linked glycosylation of mucins
R-HSA-977068 Termination of O-glycan biosynthesis

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MUC12 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10071

Protein Ontology

More...
PROi
PR:Q9UKN1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000205277 Expressed in 94 organ(s), highest expression level in mucosa of sigmoid colon
CleanExiHS_MUC12
ExpressionAtlasiQ9UKN1 baseline and differential
GenevisibleiQ9UKN1 HS

Family and domain databases

InterProiView protein in InterPro
IPR013032 EGF-like_CS
IPR000082 SEA_dom
IPR036364 SEA_dom_sf
PfamiView protein in Pfam
PF01390 SEA, 1 hit
SUPFAMiSSF82671 SSF82671, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS50024 SEA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMUC12_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UKN1
Secondary accession number(s): A6ND38, F5GWV9, Q9UKN0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: January 16, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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