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Entry version 164 (16 Oct 2019)
Sequence version 1 (01 May 2000)
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Protein

A-kinase anchor protein 11

Gene

AKAP11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to type II regulatory subunits of protein kinase A and anchors/targets them.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • protein kinase A binding Source: GO_Central
  • protein phosphatase 1 binding Source: ProtInc

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
A-kinase anchor protein 11
Short name:
AKAP-11
Alternative name(s):
A-kinase anchor protein 220 kDa
Short name:
AKAP 220
Short name:
hAKAP220
Protein kinase A-anchoring protein 11
Short name:
PRKA11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AKAP11
Synonyms:AKAP220, KIAA0629
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:369 AKAP11

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604696 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UKA4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
11215

Open Targets

More...
OpenTargetsi
ENSG00000023516

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24663

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UKA4

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
AKAP11

Domain mapping of disease mutations (DMDM)

More...
DMDMi
13431310

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000645171 – 1901A-kinase anchor protein 11Add BLAST1901

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei18PhosphoserineCombined sources1
Modified residuei422PhosphoserineCombined sources1
Modified residuei433PhosphoserineCombined sources1
Modified residuei444PhosphoserineCombined sources1
Modified residuei448PhosphoserineCombined sources1
Modified residuei981PhosphothreonineCombined sources1
Modified residuei1100PhosphothreonineCombined sources1
Modified residuei1171PhosphoserineCombined sources1
Modified residuei1176PhosphoserineBy similarity1
Modified residuei1177PhosphoserineBy similarity1
Modified residuei1242PhosphoserineCombined sources1
Modified residuei1337PhosphoserineCombined sources1
Modified residuei1485PhosphothreonineCombined sources1
Modified residuei1580PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UKA4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UKA4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UKA4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UKA4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UKA4

PeptideAtlas

More...
PeptideAtlasi
Q9UKA4

PRoteomics IDEntifications database

More...
PRIDEi
Q9UKA4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
84751

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
999

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UKA4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UKA4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart, brain, lung, liver, kidney, testis and ovary. Weakly expressed in skeletal muscle, pancreas and spleen.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000023516 Expressed in 241 organ(s), highest expression level in caudate nucleus

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UKA4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039089

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116384, 46 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UKA4, 36 interactors

Molecular INTeraction database

More...
MINTi
Q9UKA4

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000025301

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1650 – 1663PKA-RII subunit binding domainAdd BLAST14

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi238 – 315Ser-richAdd BLAST78
Compositional biasi1705 – 1767Ser-richAdd BLAST63

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AKAP110 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEQB Eukaryota
ENOG410ZS5D LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153313

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000033874

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UKA4

KEGG Orthology (KO)

More...
KOi
K16527

Identification of Orthologs from Complete Genome Data

More...
OMAi
KFKFDCP

Database of Orthologous Groups

More...
OrthoDBi
43913at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UKA4

TreeFam database of animal gene trees

More...
TreeFami
TF343800

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008382 SPHK1-interactor_AKAP_110

The PANTHER Classification System

More...
PANTHERi
PTHR10226 PTHR10226, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UKA4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATFRNNHMK TKASVRKSFS EDVFQSVKSL LQSQKELCSV TAEDCLQQDE
60 70 80 90 100
HANLTEVTFL GFNEETDAAH IQDLAAVSLE LPDILNSLHF CSLNENEIIC
110 120 130 140 150
MKNINKPLDI SSDPLNQSHP SGMLCVMRVS PTSPRLRIDF IFSLLSKYAT
160 170 180 190 200
GIRYTLDTFL HQKHQLETTD EDDDDTNQSV SSIEDDFVTA FEHLEEEETS
210 220 230 240 250
KPYNDGMNIT VLRSQCDAAS QTVTGHHLET HDLKILISSG QQKSLAKPST
260 270 280 290 300
SSVNVLGHKE LPSVKTSVTT SISEPWTQRS FYRSSNASDK DSDLQKTFFS
310 320 330 340 350
SSPAYSSESE CSSPSPVIFL DEEGYQKSLK AKLELPKIPV MKDDIEDSDS
360 370 380 390 400
EVSEFFDSFD QFDELEQTLE TCLFNKDPVI GKSSQRKGHK HGKSCMNPQK
410 420 430 440 450
FKFDRPALPA NVRKPTPRKP ESPYGNLCDA PDSPRPVKAS REDSGLFSPI
460 470 480 490 500
RSSAFSPLGG CTPAECFCQT DIGGDRIHEN HDSVYYTYED YAKSISCEVL
510 520 530 540 550
GSVLRTHHTN TLSNINSIKH GENKTVTFKH GNLDQKNKSK NKSLMIKDSI
560 570 580 590 600
QKFAADLVEK SFGSAFKDLQ KGVSSCTNAL YHLAIKLTSS VLQMAFDELR
610 620 630 640 650
RQRAFSLKER AISGLANFLV SEALSNALKD LQYVKKQIFT NTVARFAADL
660 670 680 690 700
AEELVFEGIM EVCQFSYPQT PASPQCGSFD FEDKVVKLYA KDLSESVIQE
710 720 730 740 750
AFIELSQVDV TFTTKAAVSV STDNIKYVSA ESVVPSTQAV TFSPSFHNQA
760 770 780 790 800
IMVTKPVQEY KKEYTVQQAL FCTSGIVTSI PVPLAGSALL PYHISSTACQ
810 820 830 840 850
AKAHLSSDDS NSNGDSAQVH IATKNREEKA ACLRNICLPS EHNPGNQNDF
860 870 880 890 900
KPTNDDIEMQ SSSKLPNDPA IISNFSAAVV HTIVNETLES MTSLEVTKMV
910 920 930 940 950
DERTDYLTKS LKEKTPPFSH CDQAVLQCSE ASSNKDMFAD RLSKSIIKHS
960 970 980 990 1000
IDKSKSVIPN IDKNAVYKES LPVSGEESQL TPEKSPKFPD SQNQLTHCSL
1010 1020 1030 1040 1050
SAAKDCVPEC KVSMVHGSSL ETLPSCPAVT GQKSDLKESA KDQPLKKHNL
1060 1070 1080 1090 1100
NSTSLEALSF GQENPFPHSH TFSSTALTCV DGLHVEDKQK VRDRNVIPDT
1110 1120 1130 1140 1150
PPSTPLVPSR ASSEWDIKKL TKKLKGELAK EFAPATPPST PHNSSVGSLS
1160 1170 1180 1190 1200
ENEQNTIEKE EFMLKLMRSL SEEVESSESG ELPEVDVKSE HSGKKVQFAE
1210 1220 1230 1240 1250
ALATHILSLA TEMAASHLDN KIIQEPKVKN PCLNVQSQRS VSPTFLNPSD
1260 1270 1280 1290 1300
ENLKTLCNFA GDLAAEVITE AEKIAKVRNC MLFKQKKNSC YADGDEDYKV
1310 1320 1330 1340 1350
EEKLDIEAVV HPREVDPFIL SLPPSSCMSG LMYKYPSCES VTDEYAGHLI
1360 1370 1380 1390 1400
QILKQEGGNS ELIMDQYANR LAYRSVKSGL QEAAKTTKVQ CNSRMFPVPS
1410 1420 1430 1440 1450
SQVKTNKELL MFSNKEHHQE ADKKRQSKRN EGYFCKNQTC ERTLDPYRNE
1460 1470 1480 1490 1500
VSQLYSFSTS LVHSITKDAK EELTASLVGL PKSLTDSCLF EKSGYEEDNE
1510 1520 1530 1540 1550
CHVTPELPKS LQPSSQNHRF YHSTGSLNGY GCGDNVVQAV EQYAKKVVDD
1560 1570 1580 1590 1600
TLELTLGSTV FRVSETTKSA DRVTYAEKLS PLTGQACRYC DLKELHNCTG
1610 1620 1630 1640 1650
NSSQHFFRQG SLASSKPASN PKFSSRYQKS RIFHLSVPQI HVNLDKKAVL
1660 1670 1680 1690 1700
AEKIVAEAIE KAERELSSTS LAADSGIGQE GASFAESLAT ETMTAAVTNV
1710 1720 1730 1740 1750
GHAVSSSKEI EDFQSTESVS SQQMNLSIGD DSTGSWSNLS FEDEHQDESS
1760 1770 1780 1790 1800
SFHHLSESNG NSSSWSSLGL EGDLYEDNLS FPTSDSDGPD DKDEEHEDEV
1810 1820 1830 1840 1850
EGLGQDGKTL LITNIDMEPC TVDPQLRIIL QWLIASEAEV AELYFHDSAN
1860 1870 1880 1890 1900
KEFMLLSKQL QEKGWKVGDL LQAVLQYYEV MEKASSEERC KSLFDWLLEN

A
Length:1,901
Mass (Da):210,512
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0893316C46A75672
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA92117 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1303K → R in BAA92117 (PubMed:14702039).Curated1
Sequence conflicti1444 – 1469LDPYR…ITKDA → CGPSVELSPWKWQTRCGREG NSWKRE in BAA92117 (PubMed:14702039).CuratedAdd BLAST26

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_020131721S → C. Corresponds to variant dbSNP:rs2236364Ensembl.1
Natural variantiVAR_0482071070H → R. Corresponds to variant dbSNP:rs17063163Ensembl.1
Natural variantiVAR_0482081410L → F. Corresponds to variant dbSNP:rs17063167Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF176555 mRNA Translation: AAF07045.1
AL136527 Genomic DNA No translation available.
AB014529 mRNA Translation: BAA31604.2
AK002166 mRNA Translation: BAA92117.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9383.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T00384

NCBI Reference Sequences

More...
RefSeqi
NP_057332.1, NM_016248.3
XP_011533205.1, XM_011534903.2
XP_011533206.1, XM_011534904.1
XP_011533207.1, XM_011534905.1
XP_011533208.1, XM_011534906.2
XP_016875870.1, XM_017020381.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000025301; ENSP00000025301; ENSG00000023516

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11215

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:11215

UCSC genome browser

More...
UCSCi
uc001uys.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF176555 mRNA Translation: AAF07045.1
AL136527 Genomic DNA No translation available.
AB014529 mRNA Translation: BAA31604.2
AK002166 mRNA Translation: BAA92117.1 Different initiation.
CCDSiCCDS9383.1
PIRiT00384
RefSeqiNP_057332.1, NM_016248.3
XP_011533205.1, XM_011534903.2
XP_011533206.1, XM_011534904.1
XP_011533207.1, XM_011534905.1
XP_011533208.1, XM_011534906.2
XP_016875870.1, XM_017020381.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi116384, 46 interactors
IntActiQ9UKA4, 36 interactors
MINTiQ9UKA4
STRINGi9606.ENSP00000025301

PTM databases

GlyConnecti999
iPTMnetiQ9UKA4
PhosphoSitePlusiQ9UKA4

Polymorphism and mutation databases

BioMutaiAKAP11
DMDMi13431310

Proteomic databases

EPDiQ9UKA4
jPOSTiQ9UKA4
MassIVEiQ9UKA4
MaxQBiQ9UKA4
PaxDbiQ9UKA4
PeptideAtlasiQ9UKA4
PRIDEiQ9UKA4
ProteomicsDBi84751

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
11215

Genome annotation databases

EnsembliENST00000025301; ENSP00000025301; ENSG00000023516
GeneIDi11215
KEGGihsa:11215
UCSCiuc001uys.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
11215
DisGeNETi11215

GeneCards: human genes, protein and diseases

More...
GeneCardsi
AKAP11
HGNCiHGNC:369 AKAP11
HPAiHPA039089
MIMi604696 gene
neXtProtiNX_Q9UKA4
OpenTargetsiENSG00000023516
PharmGKBiPA24663

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEQB Eukaryota
ENOG410ZS5D LUCA
GeneTreeiENSGT00940000153313
HOGENOMiHOG000033874
InParanoidiQ9UKA4
KOiK16527
OMAiKFKFDCP
OrthoDBi43913at2759
PhylomeDBiQ9UKA4
TreeFamiTF343800

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
AKAP11 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
AKAP11

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
11215
PharosiQ9UKA4

Protein Ontology

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PROi
PR:Q9UKA4

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000023516 Expressed in 241 organ(s), highest expression level in caudate nucleus
GenevisibleiQ9UKA4 HS

Family and domain databases

InterProiView protein in InterPro
IPR008382 SPHK1-interactor_AKAP_110
PANTHERiPTHR10226 PTHR10226, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAKA11_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UKA4
Secondary accession number(s): O75124, Q9NUK7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: May 1, 2000
Last modified: October 16, 2019
This is version 164 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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