UniProtKB - Q9UJY5 (GGA1_HUMAN)
ADP-ribosylation factor-binding protein GGA1
GGA1
Functioni
Caution
GO - Molecular functioni
- ADP-ribosylation factor binding Source: CAFA
GO - Biological processi
- cellular protein metabolic process Source: Reactome
- Golgi to plasma membrane protein transport Source: UniProtKB
- intracellular protein transport Source: UniProtKB
- positive regulation of protein catabolic process Source: Ensembl
- protein localization Source: UniProtKB
- protein localization to cell surface Source: UniProtKB
- protein localization to ciliary membrane Source: Ensembl
- retrograde transport, endosome to Golgi Source: UniProtKB
- toxin transport Source: Ensembl
Keywordsi
Biological process | Protein transport, Transport |
Enzyme and pathway databases
PathwayCommonsi | Q9UJY5 |
Reactomei | R-HSA-8854214, TBC/RABGAPs R-HSA-977225, Amyloid fiber formation |
Protein family/group databases
TCDBi | 9.B.278.1.2, the organellar-targeting adaptor protein complex (o-apc) family |
Names & Taxonomyi
Protein namesi | Recommended name: ADP-ribosylation factor-binding protein GGA1Alternative name(s): Gamma-adaptin-related protein 1 Golgi-localized, gamma ear-containing, ARF-binding protein 1 |
Gene namesi | Name:GGA1 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000100083.18 |
HGNCi | HGNC:17842, GGA1 |
MIMi | 606004, gene |
neXtProti | NX_Q9UJY5 |
Subcellular locationi
Golgi apparatus
- trans-Golgi network membrane 1 Publication; Peripheral membrane protein
Endosome
- Endosome membrane 1 Publication; Peripheral membrane protein
- Early endosome membrane 1 Publication; Peripheral membrane protein Curated
Cytosol
- cytosol Source: GOC
Endosome
- early endosome Source: UniProtKB
- early endosome membrane Source: Reactome
- endosome membrane Source: Reactome
Golgi apparatus
- Golgi apparatus Source: HPA
Nucleus
- nucleoplasm Source: HPA
Other locations
- intracellular membrane-bounded organelle Source: HPA
- membrane Source: UniProtKB
- protein-containing complex Source: CAFA
Keywords - Cellular componenti
Endosome, Golgi apparatus, MembranePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 92 | N → A: Abolishes interaction with IGF2R. 1 Publication | 1 | |
Mutagenesisi | 182 | L → A: Abolishes interaction with ARF1, UBC and TSG101. 1 Publication | 1 | |
Mutagenesisi | 194 | N → A: Abolishes interaction with ARF1 and RABEP1. 1 Publication | 1 | |
Mutagenesisi | 197 | I → A: Abolishes interaction with ARF1, UBC and TSG101. 1 Publication | 1 | |
Mutagenesisi | 198 | K → A: Abolishes interaction with ARF1. 1 Publication | 1 | |
Mutagenesisi | 200 | M → A: Abolishes interaction with ARF1. 1 Publication | 1 | |
Mutagenesisi | 204 | D → A: Abolishes interaction with ARF1. 1 Publication | 1 | |
Mutagenesisi | 259 | M → K: Abolishes interaction with RABEP1. | 1 | |
Mutagenesisi | 260 | R → A: No effect on interaction with RABEP1. 1 Publication | 1 | |
Mutagenesisi | 260 | R → E: Abolishes interaction with RABEP1 and UBC. 1 Publication | 1 | |
Mutagenesisi | 264 | F → A: Abolishes interaction with RABEP1. 1 Publication | 1 | |
Mutagenesisi | 267 | A → D: Abolishes interaction with RABEP1 and UBC. 1 Publication | 1 | |
Mutagenesisi | 277 | L → A: Abolishes interaction with RABEP1, UBC and TSG101. 1 Publication | 1 | |
Mutagenesisi | 281 | L → A: Abolishes interaction with RABEP1. 1 Publication | 1 | |
Mutagenesisi | 284 | N → A: Abolishes interaction with RABEP1. 1 Publication | 1 | |
Mutagenesisi | 284 | N → S: Abolishes interaction with RABEP1. 1 Publication | 1 | |
Mutagenesisi | 355 | S → A: Increased interaction with IGF2R. Reduced phosphorylation. No effect on the interaction with SORL1. 2 Publications | 1 | |
Mutagenesisi | 355 | S → D: Abolishes interaction with IGF2R. No effect on the interaction with SORL1. 2 Publications | 1 | |
Mutagenesisi | 356 – 360 | LLDDE → AADAA: Partial loss of clathrin-binding. 1 Publication | 5 | |
Mutagenesisi | 358 | D → A: Increased interaction with IGF2R. 1 Publication | 1 | |
Mutagenesisi | 361 – 362 | LM → AA: Increased interaction with IGF2R. 1 Publication | 2 | |
Mutagenesisi | 563 | A → D: Abolishes interaction with CCDC91. 1 Publication | 1 | |
Mutagenesisi | 564 | V → D: Abolishes interaction with CCDC91. 1 Publication | 1 | |
Mutagenesisi | 570 | V → E: Abolishes interaction with CCDC91. 1 Publication | 1 | |
Mutagenesisi | 572 | L → E: Abolishes interaction with CCDC91. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 26088 |
OpenTargetsi | ENSG00000100083 |
PharmGKBi | PA28657 |
Miscellaneous databases
Pharosi | Q9UJY5, Tbio |
Polymorphism and mutation databases
BioMutai | GGA1 |
DMDMi | 14548066 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000212680 | 1 – 639 | ADP-ribosylation factor-binding protein GGA1Add BLAST | 639 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources | 1 | |
Modified residuei | 185 | PhosphoserineCombined sources | 1 | |
Modified residuei | 355 | Phosphoserine; by CK21 Publication | 1 | |
Modified residuei | 418 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
Acetylation, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q9UJY5 |
jPOSTi | Q9UJY5 |
MassIVEi | Q9UJY5 |
PaxDbi | Q9UJY5 |
PeptideAtlasi | Q9UJY5 |
PRIDEi | Q9UJY5 |
ProteomicsDBi | 66377 84692 [Q9UJY5-1] 84693 [Q9UJY5-2] 84694 [Q9UJY5-3] 84695 [Q9UJY5-4] 84696 [Q9UJY5-5] |
PTM databases
iPTMneti | Q9UJY5 |
PhosphoSitePlusi | Q9UJY5 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000100083, Expressed in right testis and 234 other tissues |
ExpressionAtlasi | Q9UJY5, baseline and differential |
Genevisiblei | Q9UJY5, HS |
Organism-specific databases
HPAi | ENSG00000100083, Tissue enhanced (testis) |
Interactioni
Subunit structurei
Monomer (Probable).
Interacts with GGA2 and GGA3 (PubMed:14638859). Binds to clathrin and activated ARFs, including ARF1, ARF5 and ARF6 (PubMed:11301005, PubMed:11950392, PubMed:12679809, PubMed:15143060, PubMed:22522702).
Interacts with RABEP1 and RABGEF1 (PubMed:12505986, PubMed:15143060).
Interacts with the type-I membrane proteins LRP3, M6PR/CD-MPR and IGF2R/CI-MPR (PubMed:11390366, PubMed:11387475, PubMed:12060753).
Interacts (via N-terminal VHS domain) with SORL1/sorLA and SORT1 (via C-terminal cytosolic domain) (PubMed:11821067, PubMed:17855360, PubMed:20015111).
Interacts with EPN4 (PubMed:12538641). Binds CCDC91, P200 and SYNRG (PubMed:12858163, PubMed:12808037, PubMed:10814529).
Interacts with NECAP1, NECAP2 and AFTPH/aftiphilin (PubMed:14665628).
Interacts with TSG101 and UBC (PubMed:14660606, PubMed:15143060).
Interacts with RNF11 (PubMed:20676133).
Interacts (via VHS domain) with BACE1 (via DXXLL motif); the interaction highly increases when BACE1 is phosphorylated at 'Ser-498' (PubMed:14567678, PubMed:15886016).
Interacts with CNST (By similarity).
Interacts with ADRA2B (PubMed:27901063).
Interacts with ARL3; the interaction recruits, in collaboration with RABEP1, PKD1:PKD2 complex to trans-Golgi network and is required for ciliary targeting (By similarity).
By similarityCurated23 PublicationsBinary interactionsi
Hide detailsQ9UJY5
Isoform 4 [Q9UJY5-4]
GO - Molecular functioni
- ADP-ribosylation factor binding Source: CAFA
Protein-protein interaction databases
BioGRIDi | 117540, 85 interactors |
ELMi | Q9UJY5 |
IntActi | Q9UJY5, 60 interactors |
MINTi | Q9UJY5 |
STRINGi | 9606.ENSP00000341344 |
Miscellaneous databases
RNActi | Q9UJY5, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q9UJY5 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q9UJY5 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 17 – 147 | VHSPROSITE-ProRule annotationAdd BLAST | 131 | |
Domaini | 171 – 299 | GATPROSITE-ProRule annotationAdd BLAST | 129 | |
Domaini | 510 – 631 | GAEPROSITE-ProRule annotationAdd BLAST | 122 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 114 – 274 | Interaction with ARF3Add BLAST | 161 | |
Regioni | 300 – 509 | Unstructured hingeAdd BLAST | 210 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 358 – 362 | Autoinhibitory | 5 |
Domaini
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1086, Eukaryota |
GeneTreei | ENSGT00940000156448 |
HOGENOMi | CLU_015010_0_0_1 |
InParanoidi | Q9UJY5 |
OMAi | EWSFSSA |
OrthoDBi | 594067at2759 |
PhylomeDBi | Q9UJY5 |
TreeFami | TF318574 |
Family and domain databases
DisProti | DP00314 |
Gene3Di | 1.20.58.160, 1 hit 1.25.40.90, 1 hit |
InterProi | View protein in InterPro IPR008152, Clathrin_a/b/g-adaptin_app_Ig IPR013041, Clathrin_app_Ig-like_sf IPR008942, ENTH_VHS IPR008153, GAE_dom IPR004152, GAT_dom IPR038425, GAT_sf IPR041198, GGA_N-GAT IPR002014, VHS_dom |
Pfami | View protein in Pfam PF02883, Alpha_adaptinC2, 1 hit PF03127, GAT, 1 hit PF18308, GGA_N-GAT, 1 hit PF00790, VHS, 1 hit |
SMARTi | View protein in SMART SM00809, Alpha_adaptinC2, 1 hit SM00288, VHS, 1 hit |
SUPFAMi | SSF48464, SSF48464, 1 hit SSF49348, SSF49348, 1 hit |
PROSITEi | View protein in PROSITE PS50180, GAE, 1 hit PS50909, GAT, 1 hit PS50179, VHS, 1 hit |
s (6+)i Sequence
Sequence statusi: Complete.
This entry describes 6 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 6 described isoforms and 9 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MEPAMEPETL EARINRATNP LNKELDWASI NGFCEQLNED FEGPPLATRL
60 70 80 90 100
LAHKIQSPQE WEAIQALTVL ETCMKSCGKR FHDEVGKFRF LNELIKVVSP
110 120 130 140 150
KYLGSRTSEK VKNKILELLY SWTVGLPEEV KIAEAYQMLK KQGIVKSDPK
160 170 180 190 200
LPDDTTFPLP PPRPKNVIFE DEEKSKMLAR LLKSSHPEDL RAANKLIKEM
210 220 230 240 250
VQEDQKRMEK ISKRVNAIEE VNNNVKLLTE MVMSHSQGGA AAGSSEDLMK
260 270 280 290 300
ELYQRCERMR PTLFRLASDT EDNDEALAEI LQANDNLTQV INLYKQLVRG
310 320 330 340 350
EEVNGDATAG SIPGSTSALL DLSGLDLPPA GTTYPAMPTR PGEQASPEQP
360 370 380 390 400
SASVSLLDDE LMSLGLSDPT PPSGPSLDGT GWNSFQSSDA TEPPAPALAQ
410 420 430 440 450
APSMESRPPA QTSLPASSGL DDLDLLGKTL LQQSLPPESQ QVRWEKQQPT
460 470 480 490 500
PRLTLRDLQN KSSSCSSPSS SATSLLHTVS PEPPRPPQQP VPTELSLASI
510 520 530 540 550
TVPLESIKPS NILPVTVYDQ HGFRILFHFA RDPLPGRSDV LVVVVSMLST
560 570 580 590 600
APQPIRNIVF QSAVPKVMKV KLQPPSGTEL PAFNPIVHPS AITQVLLLAN
610 620 630
PQKEKVRLRY KLTFTMGDQT YNEMGDVDQF PPPETWGSL
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketB0QYR6 | B0QYR6_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 246 | Annotation score: | ||
B0QYR5 | B0QYR5_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 105 | Annotation score: | ||
B0QYR9 | B0QYR9_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 28 | Annotation score: | ||
B0QYS3 | B0QYS3_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 70 | Annotation score: | ||
B0QYS0 | B0QYS0_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 38 | Annotation score: | ||
B0QYS1 | B0QYS1_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 40 | Annotation score: | ||
B0QYS5 | B0QYS5_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 108 | Annotation score: | ||
B0QYS2 | B0QYS2_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 59 | Annotation score: | ||
B0QYR8 | B0QYR8_HUMAN | ADP-ribosylation factor-binding pro... | GGA1 | 17 | Annotation score: |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_036522 | 239 | G → S in a breast cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs765255006Ensembl. | 1 | |
Natural variantiVAR_036523 | 484 | P → A in a breast cancer sample; somatic mutation. 1 Publication | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_042806 | 1 – 73 | Missing in isoform 3. 1 PublicationAdd BLAST | 73 | |
Alternative sequenceiVSP_057352 | 68 | T → TVRRGEATIRPPPCDDTK in isoform 6. 1 Publication | 1 | |
Alternative sequenceiVSP_001744 | 69 – 101 | Missing in isoform 2. CuratedAdd BLAST | 33 | |
Alternative sequenceiVSP_042807 | 70 – 89 | LETCM…VGKFR → RRGEATIRPPPCDDTKGGQD in isoform 5. 1 PublicationAdd BLAST | 20 | |
Alternative sequenceiVSP_042808 | 90 – 639 | Missing in isoform 5. 1 PublicationAdd BLAST | 550 | |
Alternative sequenceiVSP_042809 | 277 – 363 | Missing in isoform 4. 1 PublicationAdd BLAST | 87 |
Sequence databases
Genome annotation databases
Ensembli | ENST00000325180; ENSP00000321288; ENSG00000100083 [Q9UJY5-4] ENST00000343632; ENSP00000341344; ENSG00000100083 [Q9UJY5-1] ENST00000381756; ENSP00000371175; ENSG00000100083 [Q9UJY5-6] ENST00000406772; ENSP00000385287; ENSG00000100083 [Q9UJY5-3] |
GeneIDi | 26088 |
KEGGi | hsa:26088 |
UCSCi | uc003atc.4, human [Q9UJY5-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1J2J | X-ray | 1.60 | B | 166-210 | [»] | |
1JWF | X-ray | 2.10 | A | 1-147 | [»] | |
1JWG | X-ray | 2.00 | A/B | 1-147 | [»] | |
1NA8 | X-ray | 2.30 | A/B | 494-639 | [»] | |
1NAF | X-ray | 2.80 | A | 165-314 | [»] | |
1NWM | X-ray | 2.40 | X | 166-302 | [»] | |
1O3X | X-ray | 2.10 | A | 166-305 | [»] | |
1OM9 | X-ray | 2.50 | A/B | 494-639 | [»] | |
1OXZ | X-ray | 2.80 | A | 141-326 | [»] | |
1PY1 | X-ray | 2.60 | A/B/C/D | 2-157 | [»] | |
1UJJ | X-ray | 2.60 | A/B | 1-147 | [»] | |
1UJK | X-ray | 1.90 | A/B | 1-147 | [»] | |
1X79 | X-ray | 2.41 | A | 210-302 | [»] | |
2DWX | X-ray | 2.55 | A/B/C/D | 507-639 | [»] | |
P/Q | 376-388 | [»] | ||||
2DWY | X-ray | 2.30 | A/B/C/D | 507-639 | [»] | |
3G2S | X-ray | 1.70 | A/B | 1-147 | [»] | |
3G2T | X-ray | 2.00 | A/B | 1-147 | [»] | |
3G2U | X-ray | 2.30 | A/B | 1-147 | [»] | |
3G2V | X-ray | 2.10 | A/B | 1-147 | [»] | |
3G2W | X-ray | 2.40 | A/B | 1-147 | [»] | |
C/D | 351-364 | [»] | ||||
SMRi | Q9UJY5 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 117540, 85 interactors |
ELMi | Q9UJY5 |
IntActi | Q9UJY5, 60 interactors |
MINTi | Q9UJY5 |
STRINGi | 9606.ENSP00000341344 |
Protein family/group databases
TCDBi | 9.B.278.1.2, the organellar-targeting adaptor protein complex (o-apc) family |
PTM databases
iPTMneti | Q9UJY5 |
PhosphoSitePlusi | Q9UJY5 |
Polymorphism and mutation databases
BioMutai | GGA1 |
DMDMi | 14548066 |
Proteomic databases
EPDi | Q9UJY5 |
jPOSTi | Q9UJY5 |
MassIVEi | Q9UJY5 |
PaxDbi | Q9UJY5 |
PeptideAtlasi | Q9UJY5 |
PRIDEi | Q9UJY5 |
ProteomicsDBi | 66377 84692 [Q9UJY5-1] 84693 [Q9UJY5-2] 84694 [Q9UJY5-3] 84695 [Q9UJY5-4] 84696 [Q9UJY5-5] |
Protocols and materials databases
Antibodypediai | 12029, 224 antibodies |
DNASUi | 26088 |
Genome annotation databases
Ensembli | ENST00000325180; ENSP00000321288; ENSG00000100083 [Q9UJY5-4] ENST00000343632; ENSP00000341344; ENSG00000100083 [Q9UJY5-1] ENST00000381756; ENSP00000371175; ENSG00000100083 [Q9UJY5-6] ENST00000406772; ENSP00000385287; ENSG00000100083 [Q9UJY5-3] |
GeneIDi | 26088 |
KEGGi | hsa:26088 |
UCSCi | uc003atc.4, human [Q9UJY5-1] |
Organism-specific databases
CTDi | 26088 |
DisGeNETi | 26088 |
EuPathDBi | HostDB:ENSG00000100083.18 |
GeneCardsi | GGA1 |
HGNCi | HGNC:17842, GGA1 |
HPAi | ENSG00000100083, Tissue enhanced (testis) |
MIMi | 606004, gene |
neXtProti | NX_Q9UJY5 |
OpenTargetsi | ENSG00000100083 |
PharmGKBi | PA28657 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1086, Eukaryota |
GeneTreei | ENSGT00940000156448 |
HOGENOMi | CLU_015010_0_0_1 |
InParanoidi | Q9UJY5 |
OMAi | EWSFSSA |
OrthoDBi | 594067at2759 |
PhylomeDBi | Q9UJY5 |
TreeFami | TF318574 |
Enzyme and pathway databases
PathwayCommonsi | Q9UJY5 |
Reactomei | R-HSA-8854214, TBC/RABGAPs R-HSA-977225, Amyloid fiber formation |
Miscellaneous databases
BioGRID-ORCSi | 26088, 3 hits in 839 CRISPR screens |
ChiTaRSi | GGA1, human |
EvolutionaryTracei | Q9UJY5 |
GeneWikii | GGA1 |
GenomeRNAii | 26088 |
Pharosi | Q9UJY5, Tbio |
PROi | PR:Q9UJY5 |
RNActi | Q9UJY5, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000100083, Expressed in right testis and 234 other tissues |
ExpressionAtlasi | Q9UJY5, baseline and differential |
Genevisiblei | Q9UJY5, HS |
Family and domain databases
DisProti | DP00314 |
Gene3Di | 1.20.58.160, 1 hit 1.25.40.90, 1 hit |
InterProi | View protein in InterPro IPR008152, Clathrin_a/b/g-adaptin_app_Ig IPR013041, Clathrin_app_Ig-like_sf IPR008942, ENTH_VHS IPR008153, GAE_dom IPR004152, GAT_dom IPR038425, GAT_sf IPR041198, GGA_N-GAT IPR002014, VHS_dom |
Pfami | View protein in Pfam PF02883, Alpha_adaptinC2, 1 hit PF03127, GAT, 1 hit PF18308, GGA_N-GAT, 1 hit PF00790, VHS, 1 hit |
SMARTi | View protein in SMART SM00809, Alpha_adaptinC2, 1 hit SM00288, VHS, 1 hit |
SUPFAMi | SSF48464, SSF48464, 1 hit SSF49348, SSF49348, 1 hit |
PROSITEi | View protein in PROSITE PS50180, GAE, 1 hit PS50909, GAT, 1 hit PS50179, VHS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GGA1_HUMAN | |
Accessioni | Q9UJY5Primary (citable) accession number: Q9UJY5 Secondary accession number(s): A8K3D3 Q9UGW1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 20, 2001 |
Last sequence update: | May 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 214 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 22
Human chromosome 22: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations