UniProtKB - Q9UJU6 (DBNL_HUMAN)
Drebrin-like protein
DBNL
Functioni
Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity).
May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.
By similarity1 PublicationGO - Molecular functioni
- actin binding Source: UniProtKB
- actin filament binding Source: UniProtKB
- cadherin binding Source: BHF-UCL
- enzyme activator activity Source: ProtInc
- protein C-terminus binding Source: Ensembl
- protein domain specific binding Source: Ensembl
GO - Biological processi
- adaptive immune response Source: UniProtKB-KW
- neuron projection morphogenesis Source: UniProtKB
- podosome assembly Source: UniProtKB
- positive regulation of axon extension Source: GO_Central
- positive regulation of dendritic spine morphogenesis Source: GO_Central
- postsynaptic actin cytoskeleton organization Source: GO_Central
- Rac protein signal transduction Source: UniProtKB
- receptor-mediated endocytosis Source: InterPro
- regulation of actin filament polymerization Source: GO_Central
- ruffle assembly Source: InterPro
- synapse assembly Source: UniProtKB
Keywordsi
Molecular function | Actin-binding |
Biological process | Adaptive immunity, Endocytosis, Immunity, Transport |
Enzyme and pathway databases
PathwayCommonsi | Q9UJU6 |
Reactomei | R-HSA-264870, Caspase-mediated cleavage of cytoskeletal proteins R-HSA-6794361, Neurexins and neuroligins R-HSA-6798695, Neutrophil degranulation |
SignaLinki | Q9UJU6 |
SIGNORi | Q9UJU6 |
Names & Taxonomyi
Protein namesi | Recommended name: Drebrin-like proteinAlternative name(s): Cervical SH3P7 Cervical mucin-associated protein Drebrin-F HPK1-interacting protein of 55 kDa Short name: HIP-55 SH3 domain-containing protein 7 |
Gene namesi | Name:DBNL Synonyms:CMAP, SH3P7 ORF Names:PP5423 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2696, DBNL |
MIMi | 610106, gene |
neXtProti | NX_Q9UJU6 |
VEuPathDBi | HostDB:ENSG00000136279 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
Endosome
- Early endosome 1 Publication
Plasma membrane
- Cell membrane 1 Publication; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
Cytoskeleton
- cytoskeleton By similarity
Cytoplasm and Cytosol
- cytosol By similarity
Other locations
- lamellipodium By similarity
- ruffle By similarity
- cell cortex By similarity
- synapse By similarity
- Perikaryon By similarity
- neuron projection By similarity
- clathrin-coated vesicle membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
- podosome By similarity
- dendrite By similarity
- postsynaptic density By similarity
Note: Associates with lamellipodial actin and membrane ruffles. Colocalizes with actin and cortactin at podosome dots and podosome rosettes.By similarity
Cytoskeleton
- cortical actin cytoskeleton Source: GO_Central
- podosome Source: UniProtKB
Cytosol
- cytosol Source: Reactome
Endosome
- early endosome Source: UniProtKB-SubCell
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
- extracellular region Source: Reactome
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
Plasma Membrane
- plasma membrane Source: HPA
- postsynaptic membrane Source: GO_Central
Other locations
- cell cortex Source: UniProtKB
- clathrin-coated vesicle membrane Source: UniProtKB-SubCell
- cytoplasm Source: BHF-UCL
- dendrite Source: GO_Central
- ficolin-1-rich granule lumen Source: Reactome
- intracellular membrane-bounded organelle Source: HPA
- lamellipodium Source: UniProtKB
- perikaryon Source: UniProtKB-SubCell
- postsynaptic density Source: GO_Central
- ruffle Source: UniProtKB
- secretory granule lumen Source: Reactome
- site of polarized growth Source: GO_Central
- tertiary granule lumen Source: Reactome
Keywords - Cellular componenti
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Endosome, Golgi apparatus, Membrane, SynapsePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 361 | D → A: Abolishes cleavage by caspase-3. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 28988 |
MalaCardsi | DBNL |
OpenTargetsi | ENSG00000136279 |
PharmGKBi | PA27164 |
Miscellaneous databases
Pharosi | Q9UJU6, Tbio |
Genetic variation databases
BioMutai | DBNL |
DMDMi | 51316115 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000079793 | 1 – 430 | Drebrin-like proteinAdd BLAST | 430 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
---|---|---|---|---|---|
Modified residuei | 26 | PhosphothreonineBy similarity | 1 | ||
Modified residuei | 160 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 176 | N6-acetyllysineCombined sources | 1 | ||
Modified residuei | 232 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 269 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 272 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 275 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 283 | PhosphoserineCombined sources | 1 | ||
Modified residuei | 288 | N6-acetyllysineCombined sources | 1 | ||
Modified residuei | 291 | PhosphothreonineCombined sources | 1 | ||
Modified residuei | 334 | PhosphotyrosineBy similarity | 1 | ||
Modified residuei | 344 | PhosphotyrosineBy similarity | 1 | ||
Isoform 4 (identifier: Q9UJU6-4) | |||||
Modified residuei | 137 | PhosphoserineCombined sources | 1 | ||
Isoform 6 (identifier: Q9UJU6-6) | |||||
Modified residuei | 183 | PhosphoserineCombined sources | 1 | ||
Isoform 2 (identifier: Q9UJU6-2) | |||||
Modified residuei | 232 | PhosphoserineCombined sources | 1 | ||
Isoform 3 (identifier: Q9UJU6-3) | |||||
Modified residuei | 232 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 361 – 362 | Cleavage; by caspase-3 | 2 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | Q9UJU6 |
jPOSTi | Q9UJU6 |
MassIVEi | Q9UJU6 |
MaxQBi | Q9UJU6 |
PaxDbi | Q9UJU6 |
PeptideAtlasi | Q9UJU6 |
PRIDEi | Q9UJU6 |
ProteomicsDBi | 3878 3970 84659 [Q9UJU6-1] 84660 [Q9UJU6-2] 84661 [Q9UJU6-3] 8938 |
TopDownProteomicsi | Q9UJU6-2 [Q9UJU6-2] |
2D gel databases
OGPi | Q9UJU6 |
PTM databases
GlyGeni | Q9UJU6, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q9UJU6 |
MetOSitei | Q9UJU6 |
PhosphoSitePlusi | Q9UJU6 |
Expressioni
Gene expression databases
Bgeei | ENSG00000136279, Expressed in lower esophagus mucosa and 199 other tissues |
ExpressionAtlasi | Q9UJU6, baseline and differential |
Genevisiblei | Q9UJU6, HS |
Organism-specific databases
HPAi | ENSG00000136279, Low tissue specificity |
Interactioni
Subunit structurei
Interacts with SHANK2, SHANK3 and SYN1.
Interacts with FGD1 and DNM1.
Interacts with ANKRD54.
Interacts with COBL.
Interacts with WASL and WIPF1 (By similarity).
Interacts with MAP4K1 and PRAM1.
By similarity2 PublicationsBinary interactionsi
Q9UJU6
Isoform 2 [Q9UJU6-2]
With | #Exp. | IntAct |
---|---|---|
SH2D4A [Q9H788] | 3 | EBI-12192777,EBI-747035 |
SH3BP2 - isoform 3 [P78314-3] | 3 | EBI-12192777,EBI-12304031 |
GO - Molecular functioni
- actin binding Source: UniProtKB
- actin filament binding Source: UniProtKB
- cadherin binding Source: BHF-UCL
- protein C-terminus binding Source: Ensembl
- protein domain specific binding Source: Ensembl
Protein-protein interaction databases
BioGRIDi | 118809, 124 interactors |
IntActi | Q9UJU6, 34 interactors |
MINTi | Q9UJU6 |
STRINGi | 9606.ENSP00000417653 |
Miscellaneous databases
RNActi | Q9UJU6, protein |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | Q9UJU6 |
SMRi | Q9UJU6 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q9UJU6 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 133 | ADF-HPROSITE-ProRule annotationAdd BLAST | 130 | |
Domaini | 371 – 430 | SH3PROSITE-ProRule annotationAdd BLAST | 60 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 219 – 283 | DisorderedSequence analysisAdd BLAST | 65 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 176 – 231 | Sequence analysisAdd BLAST | 56 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 227 – 248 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 249 – 265 | Basic and acidic residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 266 – 283 | Polar residuesSequence analysisAdd BLAST | 18 |
Domaini
Sequence similaritiesi
Keywords - Domaini
Coiled coil, SH3 domainPhylogenomic databases
eggNOGi | KOG3655, Eukaryota |
GeneTreei | ENSGT00940000156732 |
HOGENOMi | CLU_013085_0_1_1 |
InParanoidi | Q9UJU6 |
OMAi | TNIDMVD |
OrthoDBi | 885776at2759 |
PhylomeDBi | Q9UJU6 |
TreeFami | TF318935 |
Family and domain databases
CDDi | cd11960, SH3_Abp1_eu, 1 hit |
Gene3Di | 3.40.20.10, 1 hit |
InterProi | View protein in InterPro IPR002108, ADF-H IPR029006, ADF-H/Gelsolin-like_dom_sf IPR029923, Dbnl IPR035717, Drebrin-like_SH3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR10829:SF12, PTHR10829:SF12, 1 hit |
Pfami | View protein in Pfam PF00241, Cofilin_ADF, 1 hit PF14604, SH3_9, 1 hit |
SMARTi | View protein in SMART SM00102, ADF, 1 hit SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51263, ADF_H, 1 hit PS50002, SH3, 1 hit |
s (6+)i Sequence
Sequence statusi: Complete.
This entry describes 6 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 6 described isoforms and 11 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAANLSRNGP ALQEAYVRVV TEKSPTDWAL FTYEGNSNDI RVAGTGEGGL
60 70 80 90 100
EEMVEELNSG KVMYAFCRVK DPNSGLPKFV LINWTGEGVN DVRKGACASH
110 120 130 140 150
VSTMASFLKG AHVTINARAE EDVEPECIME KVAKASGANY SFHKESGRFQ
160 170 180 190 200
DVGPQAPVGS VYQKTNAVSE IKRVGKDSFW AKAEKEEENR RLEEKRRAEE
210 220 230 240 250
AQRQLEQERR ERELREAARR EQRYQEQGGE ASPQRTWEQQ QEVVSRNRNE
260 270 280 290 300
QESAVHPREI FKQKERAMST TSISSPQPGK LRSPFLQKQL TQPETHFGRE
310 320 330 340 350
PAAAISRPRA DLPAEEPAPS TPPCLVQAEE EAVYEEPPEQ ETFYEQPPLV
360 370 380 390 400
QQQGAGSEHI DHHIQGQGLS GQGLCARALY DYQAADDTEI SFDPENLITG
410 420 430
IEVIDEGWWR GYGPDGHFGM FPANYVELIE
Computationally mapped potential isoform sequencesi
There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0Y5J4 | H0Y5J4_HUMAN | Drebrin-like protein | DBNL | 359 | Annotation score: | ||
B4DDD6 | B4DDD6_HUMAN | Drebrin-like protein | DBNL | 406 | Annotation score: | ||
H7C111 | H7C111_HUMAN | Drebrin-like protein | DBNL | 138 | Annotation score: | ||
F8WBG8 | F8WBG8_HUMAN | Drebrin-like protein | DBNL | 128 | Annotation score: | ||
F8WFE1 | F8WFE1_HUMAN | Drebrin-like protein | DBNL | 87 | Annotation score: | ||
F8WBB2 | F8WBB2_HUMAN | Drebrin-like protein | DBNL | 62 | Annotation score: | ||
F8WC20 | F8WC20_HUMAN | Drebrin-like protein | DBNL | 50 | Annotation score: | ||
F2Z2V3 | F2Z2V3_HUMAN | Drebrin-like protein | DBNL | 27 | Annotation score: | ||
F8WB73 | F8WB73_HUMAN | Drebrin-like protein | DBNL | 31 | Annotation score: | ||
F8WCK3 | F8WCK3_HUMAN | Drebrin-like protein | DBNL | 40 | Annotation score: | ||
There is more potential isoformShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 8 | N → K in AAG17262 (PubMed:15498874).Curated | 1 | |
Sequence conflicti | 98 | A → S in AAF81273 (Ref. 3) Curated | 1 | |
Sequence conflicti | 98 | A → S in AAG13120 (Ref. 3) Curated | 1 | |
Sequence conflicti | 235 | R → S in AAF81273 (Ref. 3) Curated | 1 | |
Sequence conflicti | 235 | R → S in AAG13120 (Ref. 3) Curated | 1 | |
Sequence conflicti | 430 | E → D in CAG33448 (Ref. 6) Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_054779 | 1 – 109 | MAANL…ASFLK → MKATAMTSAWLAQG in isoform 4. CuratedAdd BLAST | 109 | |
Alternative sequenceiVSP_054780 | 1 – 103 | Missing in isoform 5. 1 PublicationAdd BLAST | 103 | |
Alternative sequenceiVSP_057346 | 110 – 158 | Missing in isoform 6. 1 PublicationAdd BLAST | 49 | |
Alternative sequenceiVSP_011398 | 234 | Q → QS in isoform 2, isoform 3, isoform 4 and isoform 6. 2 Publications | 1 | |
Alternative sequenceiVSP_011399 | 251 | Q → QGSTCASLQ in isoform 3. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF197060 mRNA Translation: AAF13701.1 AF077353 mRNA Translation: AAF80228.1 AF250287 mRNA Translation: AAF81273.1 AF151364 mRNA Translation: AAG13120.1 AF218020 mRNA Translation: AAG17262.2 AK027367 mRNA Translation: BAB55065.1 AK293279 mRNA Translation: BAG56807.1 AK293698 mRNA Translation: BAG57133.1 CR457167 mRNA Translation: CAG33448.1 AC017116 Genomic DNA No translation available. CH236960 Genomic DNA Translation: EAL23770.1 CH471128 Genomic DNA Translation: EAW61132.1 BC011677 mRNA Translation: AAH11677.1 BC031687 mRNA Translation: AAH31687.1 |
CCDSi | CCDS34622.1 [Q9UJU6-2] CCDS34623.1 [Q9UJU6-1] CCDS47579.1 [Q9UJU6-3] CCDS64633.1 [Q9UJU6-4] CCDS64634.1 [Q9UJU6-5] |
RefSeqi | NP_001014436.1, NM_001014436.2 [Q9UJU6-1] NP_001116428.1, NM_001122956.1 [Q9UJU6-3] NP_001271242.1, NM_001284313.1 [Q9UJU6-5] NP_001271244.1, NM_001284315.1 [Q9UJU6-4] NP_054782.2, NM_014063.6 [Q9UJU6-2] |
Genome annotation databases
Ensembli | ENST00000440166.5; ENSP00000415173.1; ENSG00000136279.21 [Q9UJU6-5] ENST00000448521.6; ENSP00000411701.1; ENSG00000136279.21 ENST00000456905.5; ENSP00000416421.1; ENSG00000136279.21 [Q9UJU6-6] ENST00000468694.5; ENSP00000417653.1; ENSG00000136279.21 [Q9UJU6-3] ENST00000490734.6; ENSP00000417749.2; ENSG00000136279.21 [Q9UJU6-4] ENST00000494774.5; ENSP00000419992.1; ENSG00000136279.21 [Q9UJU6-2] |
GeneIDi | 28988 |
KEGGi | hsa:28988 |
MANE-Selecti | ENST00000448521.6; ENSP00000411701.1; NM_001014436.3; NP_001014436.1 |
UCSCi | uc003tjo.5, human [Q9UJU6-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF197060 mRNA Translation: AAF13701.1 AF077353 mRNA Translation: AAF80228.1 AF250287 mRNA Translation: AAF81273.1 AF151364 mRNA Translation: AAG13120.1 AF218020 mRNA Translation: AAG17262.2 AK027367 mRNA Translation: BAB55065.1 AK293279 mRNA Translation: BAG56807.1 AK293698 mRNA Translation: BAG57133.1 CR457167 mRNA Translation: CAG33448.1 AC017116 Genomic DNA No translation available. CH236960 Genomic DNA Translation: EAL23770.1 CH471128 Genomic DNA Translation: EAW61132.1 BC011677 mRNA Translation: AAH11677.1 BC031687 mRNA Translation: AAH31687.1 |
CCDSi | CCDS34622.1 [Q9UJU6-2] CCDS34623.1 [Q9UJU6-1] CCDS47579.1 [Q9UJU6-3] CCDS64633.1 [Q9UJU6-4] CCDS64634.1 [Q9UJU6-5] |
RefSeqi | NP_001014436.1, NM_001014436.2 [Q9UJU6-1] NP_001116428.1, NM_001122956.1 [Q9UJU6-3] NP_001271242.1, NM_001284313.1 [Q9UJU6-5] NP_001271244.1, NM_001284315.1 [Q9UJU6-4] NP_054782.2, NM_014063.6 [Q9UJU6-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1X67 | NMR | - | A | 1-133 | [»] | |
AlphaFoldDBi | Q9UJU6 | |||||
SMRi | Q9UJU6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 118809, 124 interactors |
IntActi | Q9UJU6, 34 interactors |
MINTi | Q9UJU6 |
STRINGi | 9606.ENSP00000417653 |
PTM databases
GlyGeni | Q9UJU6, 1 site, 1 O-linked glycan (1 site) |
iPTMneti | Q9UJU6 |
MetOSitei | Q9UJU6 |
PhosphoSitePlusi | Q9UJU6 |
Genetic variation databases
BioMutai | DBNL |
DMDMi | 51316115 |
2D gel databases
OGPi | Q9UJU6 |
Proteomic databases
EPDi | Q9UJU6 |
jPOSTi | Q9UJU6 |
MassIVEi | Q9UJU6 |
MaxQBi | Q9UJU6 |
PaxDbi | Q9UJU6 |
PeptideAtlasi | Q9UJU6 |
PRIDEi | Q9UJU6 |
ProteomicsDBi | 3878 3970 84659 [Q9UJU6-1] 84660 [Q9UJU6-2] 84661 [Q9UJU6-3] 8938 |
TopDownProteomicsi | Q9UJU6-2 [Q9UJU6-2] |
Protocols and materials databases
ABCDi | Q9UJU6, 5 sequenced antibodies |
Antibodypediai | 13203, 266 antibodies from 35 providers |
DNASUi | 28988 |
Genome annotation databases
Organism-specific databases
CTDi | 28988 |
DisGeNETi | 28988 |
GeneCardsi | DBNL |
HGNCi | HGNC:2696, DBNL |
HPAi | ENSG00000136279, Low tissue specificity |
MalaCardsi | DBNL |
MIMi | 610106, gene |
neXtProti | NX_Q9UJU6 |
OpenTargetsi | ENSG00000136279 |
PharmGKBi | PA27164 |
VEuPathDBi | HostDB:ENSG00000136279 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3655, Eukaryota |
GeneTreei | ENSGT00940000156732 |
HOGENOMi | CLU_013085_0_1_1 |
InParanoidi | Q9UJU6 |
OMAi | TNIDMVD |
OrthoDBi | 885776at2759 |
PhylomeDBi | Q9UJU6 |
TreeFami | TF318935 |
Enzyme and pathway databases
PathwayCommonsi | Q9UJU6 |
Reactomei | R-HSA-264870, Caspase-mediated cleavage of cytoskeletal proteins R-HSA-6794361, Neurexins and neuroligins R-HSA-6798695, Neutrophil degranulation |
SignaLinki | Q9UJU6 |
SIGNORi | Q9UJU6 |
Miscellaneous databases
BioGRID-ORCSi | 28988, 15 hits in 1074 CRISPR screens |
ChiTaRSi | DBNL, human |
EvolutionaryTracei | Q9UJU6 |
GeneWikii | Drebrin-like |
GenomeRNAii | 28988 |
Pharosi | Q9UJU6, Tbio |
PROi | PR:Q9UJU6 |
RNActi | Q9UJU6, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000136279, Expressed in lower esophagus mucosa and 199 other tissues |
ExpressionAtlasi | Q9UJU6, baseline and differential |
Genevisiblei | Q9UJU6, HS |
Family and domain databases
CDDi | cd11960, SH3_Abp1_eu, 1 hit |
Gene3Di | 3.40.20.10, 1 hit |
InterProi | View protein in InterPro IPR002108, ADF-H IPR029006, ADF-H/Gelsolin-like_dom_sf IPR029923, Dbnl IPR035717, Drebrin-like_SH3 IPR036028, SH3-like_dom_sf IPR001452, SH3_domain |
PANTHERi | PTHR10829:SF12, PTHR10829:SF12, 1 hit |
Pfami | View protein in Pfam PF00241, Cofilin_ADF, 1 hit PF14604, SH3_9, 1 hit |
SMARTi | View protein in SMART SM00102, ADF, 1 hit SM00326, SH3, 1 hit |
SUPFAMi | SSF50044, SSF50044, 1 hit |
PROSITEi | View protein in PROSITE PS51263, ADF_H, 1 hit PS50002, SH3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DBNL_HUMAN | |
Accessioni | Q9UJU6Primary (citable) accession number: Q9UJU6 Secondary accession number(s): A4D2I9 Q9NR72 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 16, 2004 |
Last sequence update: | May 1, 2000 | |
Last modified: | May 25, 2022 | |
This is version 192 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 7
Human chromosome 7: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families