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Protein

Potassium voltage-gated channel subfamily E regulatory beta subunit 5

Gene

KCNE5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Potassium channel ancillary subunit that is essential for generation of some native K+ currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ion channel binding Source: BHF-UCL
  • potassium channel regulator activity Source: BHF-UCL
  • voltage-gated potassium channel activity Source: InterPro

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5576890 Phase 3 - rapid repolarisation
R-HSA-5576893 Phase 2 - plateau phase

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.10.3.2 the slow voltage-gated k+) channel accessory protein (mink) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Potassium voltage-gated channel subfamily E regulatory beta subunit 5
Alternative name(s):
AMME syndrome candidate gene 2 protein
Potassium channel subunit beta MiRP4
Potassium voltage-gated channel subfamily E member 1-like protein1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KCNE5
Synonyms:AMMECR2, KCNE1L1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000176076.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6241 KCNE5

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
300328 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UJ90

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei61 – 81HelicalSequence analysisAdd BLAST21
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini82 – 142CytoplasmicSequence analysisAdd BLAST61

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Alport syndrome with mental retardation, midface hypoplasia and elliptocytosis (ATS-MR)1 Publication
The gene represented in this entry may be involved in disease pathogenesis.1 Publication
Disease descriptionA X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, sensorineural hearing loss, mental retardation, midface hypoplasia and elliptocytosis.
See also OMIM:300194

Keywords - Diseasei

Alport syndrome, Deafness, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation

Organism-specific databases

DisGeNET

More...
DisGeNETi
23630

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
KCNE5

MalaCards human disease database

More...
MalaCardsi
KCNE5
MIMi300194 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000176076

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
86818 Alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome
130 Brugada syndrome

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30031

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KCNE5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001442941 – 142Potassium voltage-gated channel subfamily E regulatory beta subunit 5Add BLAST142

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi2N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi25N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UJ90

PRoteomics IDEntifications database

More...
PRIDEi
Q9UJ90

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84602

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UJ90

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000176076 Expressed in 68 organ(s), highest expression level in substantia nigra

CleanEx database of gene expression profiles

More...
CleanExi
HS_KCNE1L

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UJ90 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042316

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with KCNQ1; impairs KCNQ1 localization in lipid rafts and only conducts current upon strong and continued depolarization.2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117161, 3 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9UJ90

Protein interaction database and analysis system

More...
IntActi
Q9UJ90, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000361173

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UJ90

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UJ90

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the potassium channel KCNE family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JC0Y Eukaryota
ENOG4111A5J LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155001

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113204

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG052221

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UJ90

KEGG Orthology (KO)

More...
KOi
K04895

Identification of Orthologs from Complete Genome Data

More...
OMAi
EPSQACA

Database of Orthologous Groups

More...
OrthoDBi
1612727at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UJ90

TreeFam database of animal gene trees

More...
TreeFami
TF335981

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000369 K_chnl_KCNE

The PANTHER Classification System

More...
PANTHERi
PTHR15282 PTHR15282, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02060 ISK_Channel, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UJ90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNCSESQRLR TLLSRLLLEL HHRGNASGLG AGPRPSMGMG VVPDPFVGRE
60 70 80 90 100
VTSAKGDDAY LYILLIMIFY ACLAGGLILA YTRSRKLVEA KDEPSQACAE
110 120 130 140
HEWAPGGALT ADAEAAAGSQ AEGRRQLASE GLPALAQGAE RV
Length:142
Mass (Da):14,993
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED8EC611CDE66BFE
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05303733P → S1 PublicationCorresponds to variant dbSNP:rs17003955Ensembl.1
Natural variantiVAR_07267965L → F Found in patients with atrial fibrillation; unknown pathological significance; loss of its inhibitory effects on KCNQ1. 1 PublicationCorresponds to variant dbSNP:rs1364685385Ensembl.1
Natural variantiVAR_07268081Y → H Found in patients with ventricular fibrillation; unknown pathological significance; loss of its inhibitory effects on KCNQ1. 1 PublicationCorresponds to variant dbSNP:rs199924386EnsemblClinVar.1
Natural variantiVAR_034048114E → Q. Corresponds to variant dbSNP:rs41312935Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ012743 mRNA Translation: CAB58359.1
AK314923 mRNA Translation: BAG37431.1
DQ784807 Genomic DNA Translation: ABQ01242.1
EF535525 mRNA Translation: ABQ08564.1
CH471120 Genomic DNA Translation: EAX02676.1
BC035330 mRNA Translation: AAH35330.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14547.1

NCBI Reference Sequences

More...
RefSeqi
NP_036414.1, NM_012282.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.522753

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000372101; ENSP00000361173; ENSG00000176076

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23630

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23630

UCSC genome browser

More...
UCSCi
uc004eoh.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ012743 mRNA Translation: CAB58359.1
AK314923 mRNA Translation: BAG37431.1
DQ784807 Genomic DNA Translation: ABQ01242.1
EF535525 mRNA Translation: ABQ08564.1
CH471120 Genomic DNA Translation: EAX02676.1
BC035330 mRNA Translation: AAH35330.1
CCDSiCCDS14547.1
RefSeqiNP_036414.1, NM_012282.3
UniGeneiHs.522753

3D structure databases

ProteinModelPortaliQ9UJ90
SMRiQ9UJ90
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117161, 3 interactors
CORUMiQ9UJ90
IntActiQ9UJ90, 4 interactors
STRINGi9606.ENSP00000361173

Protein family/group databases

TCDBi8.A.10.3.2 the slow voltage-gated k+) channel accessory protein (mink) family

PTM databases

PhosphoSitePlusiQ9UJ90

Polymorphism and mutation databases

BioMutaiKCNE5

Proteomic databases

PaxDbiQ9UJ90
PRIDEiQ9UJ90
ProteomicsDBi84602

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
23630
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000372101; ENSP00000361173; ENSG00000176076
GeneIDi23630
KEGGihsa:23630
UCSCiuc004eoh.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23630
DisGeNETi23630
EuPathDBiHostDB:ENSG00000176076.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KCNE5
GeneReviewsiKCNE5
HGNCiHGNC:6241 KCNE5
HPAiHPA042316
MalaCardsiKCNE5
MIMi300194 phenotype
300328 gene
neXtProtiNX_Q9UJ90
OpenTargetsiENSG00000176076
Orphaneti86818 Alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome
130 Brugada syndrome
PharmGKBiPA30031

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JC0Y Eukaryota
ENOG4111A5J LUCA
GeneTreeiENSGT00940000155001
HOGENOMiHOG000113204
HOVERGENiHBG052221
InParanoidiQ9UJ90
KOiK04895
OMAiEPSQACA
OrthoDBi1612727at2759
PhylomeDBiQ9UJ90
TreeFamiTF335981

Enzyme and pathway databases

ReactomeiR-HSA-5576890 Phase 3 - rapid repolarisation
R-HSA-5576893 Phase 2 - plateau phase

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
KCNE1L

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
23630

Protein Ontology

More...
PROi
PR:Q9UJ90

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000176076 Expressed in 68 organ(s), highest expression level in substantia nigra
CleanExiHS_KCNE1L
GenevisibleiQ9UJ90 HS

Family and domain databases

InterProiView protein in InterPro
IPR000369 K_chnl_KCNE
PANTHERiPTHR15282 PTHR15282, 1 hit
PfamiView protein in Pfam
PF02060 ISK_Channel, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKCNE5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UJ90
Secondary accession number(s): Q5JWV7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 13, 2002
Last sequence update: May 1, 2000
Last modified: January 16, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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