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Entry version 101 (08 May 2019)
Sequence version 2 (16 Sep 2015)
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Protein

MAGE-like protein 2

Gene

MAGEL2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Acts as a regulator of retrograde transport via its interaction with VPS35. Recruited to retromer-containing endosomes and promotes the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1 together with TRIM27, leading to promote endosomal F-actin assembly (PubMed:23452853). Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Significantly promotes the cytoplasmic accumulation of CLOCK (By similarity).By similarity2 Publications

Miscellaneous

Imprinted, expressed from the paternal chromosome only.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processBiological rhythms, Transcription, Transcription regulation, Transport, Ubl conjugation pathway

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q9UJ55

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MAGE-like protein 2
Alternative name(s):
Necdin-like protein 1
Protein nM15
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MAGEL2
Synonyms:NDNL1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6814 MAGEL2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605283 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UJ55

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endosome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Schaaf-Yang syndrome (SHFYNG)1 Publication
The disease is caused by mutations affecting the gene represented in this entry. All mutations occurred on the paternal allele.
Disease descriptionA disease characterized by clinical features of Prader-Willi syndrome, including neonatal hypotonia with poor suck, feeding problems in infancy, obesity, developmental delay, short stature, and hypogonadism. Additionally, patients manifest autism spectrum disorder. Some patients have dysmorphic facial features.
See also OMIM:615547

Keywords - Diseasei

Autism spectrum disorder, Mental retardation, Obesity

Organism-specific databases

DisGeNET

More...
DisGeNETi
54551

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
MAGEL2

MalaCards human disease database

More...
MalaCardsi
MAGEL2
MIMi615547 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000254585

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
398069 Prader-Willi syndrome due to a point mutation
177910 Prader-Willi syndrome due to imprinting mutation
98754 Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15
177901 Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1
177904 Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MAGEL2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
17380152

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001567381 – 1249MAGE-like protein 2Add BLAST1249

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UJ55

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UJ55

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UJ55

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UJ55

PeptideAtlas

More...
PeptideAtlasi
Q9UJ55

PRoteomics IDEntifications database

More...
PRIDEi
Q9UJ55

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84587

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UJ55

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UJ55

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in placenta, fetal and adult brain. Not detected in heart and small intestine, very low levels in fibroblasts. Not expressed in brain of a Prader-Willi patient.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000254585 Expressed in 98 organ(s), highest expression level in metanephros

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TRIM27. Interacts with VPS35; leading to recruitment at retromer-containing endosomes. Interacts with ARNTL/BMAL1 and PER2 (By similarity).By similarity2 Publications

Protein-protein interaction databases

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9UJ55

Protein interaction database and analysis system

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IntActi
Q9UJ55, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000433433

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UJ55

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1020 – 1219MAGEPROSITE-ProRule annotationAdd BLAST200

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi13 – 700Pro-richPROSITE-ProRule annotationAdd BLAST688

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4562 Eukaryota
ENOG4111S70 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163006

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UJ55

Identification of Orthologs from Complete Genome Data

More...
OMAi
GTPMAHP

Database of Orthologous Groups

More...
OrthoDBi
1195799at2759

TreeFam database of animal gene trees

More...
TreeFami
TF328505

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.1200, 1 hit
1.10.10.1210, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037445 MAGE
IPR041898 MAGE_WH1
IPR041899 MAGE_WH2
IPR002190 MHD_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11736 PTHR11736, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01454 MAGE, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01373 MAGE, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50838 MAGE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UJ55-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQLSKNLGD SSPPAEAPKP PVYSRPTVLM RAPPASSRAP PVPWDPPPID
60 70 80 90 100
LQASLAAWQA PQPAWEAPQG QLPAPVVPMT QPPALGGPIV PAPPLGGPMG
110 120 130 140 150
KPPTPGVLMV HPPPPGAPMA QPPTPGVLMV HPSAPGAPMA HPPPPGTPMS
160 170 180 190 200
HPPPPGTPMA HPPPPGTPMA HPPPPGTPMV HPPPPGTPMA HPPPPGTPMA
210 220 230 240 250
HPPPPGTPMA HPPPPGTPMA HPPPPGTPMA QPPAPGVLMA QPLTPGVLMV
260 270 280 290 300
QPAAPGAPMV QPPPAAMMTQ PQPSGAPMAK PPGPGVLMIH PPGARAPMTQ
310 320 330 340 350
PPASGAPMAQ PAAPPAQPMA PPAQPMASWA PQAQPLILQI QSQVIRAPPQ
360 370 380 390 400
VPQGPQAPPA QLATPPGWQA TSPGWQATQQ GWQATPLTWQ TTQVTWQAPA
410 420 430 440 450
VTWQVPPPMR QGPPPIRPGP PPIRPGPPPV RQAPPLIRQA PPVIRQAPPV
460 470 480 490 500
IRQAPPVIRQ APAVIRQAPP VIRQAPPVIR QAPPVIRQAP PLIRQAPPPI
510 520 530 540 550
RPAPQVLATQ PPLWQALPPP PPLRQAPQAR LPAPQVQAAP QVPTAPPATQ
560 570 580 590 600
VPAAPPAGPQ VPQPVLPAPL SAPLSAPQAV HCPSIIWQAP KGQPPVPHEI
610 620 630 640 650
PTSMEFQEVQ QTQALAWQAQ KAPTHIWQPL PAQEAQRQAP PLVQLEQPFQ
660 670 680 690 700
GAPPSQKAVQ IQLPPQQAQA SGPQAEVPTL PLQPSWQAPP AVLQAQPGPP
710 720 730 740 750
VAAANFPLGS AKSLMTPSGE CRASSIDRRG SSKERRTSSK ERRAPSKDRM
760 770 780 790 800
IFAATFCAPK AVSAARAHLP AAWKNLPATP ETFAPSSSVF PATSQFQPAS
810 820 830 840 850
LNAFKGPSAA SETPKSLPYA LQDPFACVEA LPAVPWVPQP NMNASKASQA
860 870 880 890 900
VPTFLMATAA APQATATTQE ASKTSVEPPR RSGKATRKKK HLEAQEDSRG
910 920 930 940 950
HTLAFHDWQG PRPWENLNLS DWEVQSPIQV SGDWEHPNTP RGLSGWEGPS
960 970 980 990 1000
TSRILSGWEG PSASWALSAW EGPSTSRALG LSESPGSSLP VVVSEVASVS
1010 1020 1030 1040 1050
PGSSATQDNS KVEAQPLSPL DERANALVQF LLVKDQAKVP VQRSEMVKVI
1060 1070 1080 1090 1100
LREYKDECLD IINRANNKLE CAFGYQLKEI DTKNHAYIII NKLGYHTGNL
1110 1120 1130 1140 1150
VASYLDRPKF GLLMVVLSLI FMKGNCVRED LIFNFLFKLG LDVRETNGLF
1160 1170 1180 1190 1200
GNTKKLITEV FVRQKYLEYR RIPYTEPAEY EFLWGPRAFL ETSKMLVLRF
1210 1220 1230 1240
LAKLHKKDPQ SWPFHYLEAL AECEWEDTDE DEPDTGDSAH GPTSRPPPR
Length:1,249
Mass (Da):132,822
Last modified:September 16, 2015 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i17AA2FB3F8477D82
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG28577 differs from that shown. Reason: Frameshift at position 730.Curated
The sequence CAB62393 differs from that shown. Reason: Frameshift at position 730.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC124309 Genomic DNA No translation available.
AF200625 Genomic DNA Translation: AAG28577.1 Frameshift.
AJ243531 mRNA Translation: CAB62393.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS73700.1

NCBI Reference Sequences

More...
RefSeqi
NP_061939.3, NM_019066.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000532292; ENSP00000433433; ENSG00000254585
ENST00000650528; ENSP00000497810; ENSG00000254585

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54551

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54551

UCSC genome browser

More...
UCSCi
uc001ywj.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124309 Genomic DNA No translation available.
AF200625 Genomic DNA Translation: AAG28577.1 Frameshift.
AJ243531 mRNA Translation: CAB62393.1 Frameshift.
CCDSiCCDS73700.1
RefSeqiNP_061939.3, NM_019066.4

3D structure databases

SMRiQ9UJ55
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

CORUMiQ9UJ55
IntActiQ9UJ55, 3 interactors
STRINGi9606.ENSP00000433433

PTM databases

iPTMnetiQ9UJ55
PhosphoSitePlusiQ9UJ55

Polymorphism and mutation databases

BioMutaiMAGEL2
DMDMi17380152

Proteomic databases

EPDiQ9UJ55
jPOSTiQ9UJ55
MaxQBiQ9UJ55
PaxDbiQ9UJ55
PeptideAtlasiQ9UJ55
PRIDEiQ9UJ55
ProteomicsDBi84587

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000532292; ENSP00000433433; ENSG00000254585
ENST00000650528; ENSP00000497810; ENSG00000254585
GeneIDi54551
KEGGihsa:54551
UCSCiuc001ywj.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54551
DisGeNETi54551

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MAGEL2
GeneReviewsiMAGEL2

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0026903
HGNCiHGNC:6814 MAGEL2
MalaCardsiMAGEL2
MIMi605283 gene
615547 phenotype
neXtProtiNX_Q9UJ55
OpenTargetsiENSG00000254585
Orphaneti398069 Prader-Willi syndrome due to a point mutation
177910 Prader-Willi syndrome due to imprinting mutation
98754 Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15
177901 Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1
177904 Prader-Willi syndrome due to paternal deletion of 15q11q13 type 2

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4562 Eukaryota
ENOG4111S70 LUCA
GeneTreeiENSGT00940000163006
InParanoidiQ9UJ55
OMAiGTPMAHP
OrthoDBi1195799at2759
TreeFamiTF328505

Enzyme and pathway databases

SIGNORiQ9UJ55

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54551

Protein Ontology

More...
PROi
PR:Q9UJ55

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000254585 Expressed in 98 organ(s), highest expression level in metanephros

Family and domain databases

Gene3Di1.10.10.1200, 1 hit
1.10.10.1210, 1 hit
InterProiView protein in InterPro
IPR037445 MAGE
IPR041898 MAGE_WH1
IPR041899 MAGE_WH2
IPR002190 MHD_dom
PANTHERiPTHR11736 PTHR11736, 2 hits
PfamiView protein in Pfam
PF01454 MAGE, 2 hits
SMARTiView protein in SMART
SM01373 MAGE, 1 hit
PROSITEiView protein in PROSITE
PS50838 MAGE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAGL2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UJ55
Secondary accession number(s): H0YDD5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: September 16, 2015
Last modified: May 8, 2019
This is version 101 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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