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Entry version 117 (11 Dec 2019)
Sequence version 2 (20 May 2008)
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Protein

Short coiled-coil protein

Gene

SCOC

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Positive regulator of amino acid starvation-induced autophagy.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Short coiled-coil protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCOC
Synonyms:SCOCO
ORF Names:HRIHFB2072
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000153130.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20335 SCOC

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UIL1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi93E → V: Causes trimerization and impairs interaction with FEZ1 coiled coil but does not impair interaction with full-length FEZ1; when associated with L-97. 1 Publication1
Mutagenesisi97K → L: Causes trimerization and impairs interaction with FEZ1 coiled coil but does not impair interaction with full-length FEZ1; when associated with V-93. 1 Publication1
Mutagenesisi117R → E: Impairs interaction with FEZ1 coiled coil but does not impair interaction with full-length FEZ1. 1 Publication1
Mutagenesisi125N → L: Causes tetramerization and loss of interaction with FEZ1; when associated with V-132. 1 Publication1
Mutagenesisi132N → V: Causes tetramerization and loss of interaction with FEZ1; when associated with L-125. 1 Publication1

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000153130

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134972148

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UIL1 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SCOC

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189046186

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003341641 – 159Short coiled-coil proteinAdd BLAST159

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UIL1

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9UIL1

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q9UIL1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UIL1

PeptideAtlas

More...
PeptideAtlasi
Q9UIL1

PRoteomics IDEntifications database

More...
PRIDEi
Q9UIL1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
19156
84542 [Q9UIL1-1]
84543 [Q9UIL1-2]
84544 [Q9UIL1-3]
84545 [Q9UIL1-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UIL1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UIL1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with highest levels in brain, heart and skeletal muscle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000153130 Expressed in 203 organ(s), highest expression level in lateral nuclear group of thalamus

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UIL1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UIL1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA061198
HPA070321

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (PubMed:24098481).

Interacts with ARL1, ARL2 and ARL3 (PubMed:11303027). Directly interacts with FEZ1 and UVRAG (PubMed:22354037, PubMed:24098481). The interaction with UVRAG is reduced by amino acid starvation, but the complex is stabilized in the presence of FEZ1.

Interacts with NRBF2 (PubMed:22354037).

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121943, 34 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UIL1, 38 interactors

Molecular INTeraction database

More...
MINTi
Q9UIL1

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000477352

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9UIL1 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1159
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UIL1

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili78 – 146Combined sources1 PublicationAdd BLAST69

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SCOC family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3650 Eukaryota
ENOG4111R9Q LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008828

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UIL1

KEGG Orthology (KO)

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KOi
K20316

Identification of Orthologs from Complete Genome Data

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OMAi
NCDIDAG

Database of Orthologous Groups

More...
OrthoDBi
1581498at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UIL1

TreeFam database of animal gene trees

More...
TreeFami
TF323340

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR019357 SCOC

The PANTHER Classification System

More...
PANTHERi
PTHR21614 PTHR21614, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10224 DUF2205, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UIL1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRRRVFSSQD WRASGWDGMG FFSRRTFCGR SGRSCRGQLV QVSRPEVSAG
60 70 80 90 100
SLLLPAPQAE DHSSRILYPR PKSLLPKMMN ADMDAVDAEN QVELEEKTRL
110 120 130 140 150
INQVLELQHT LEDLSARVDA VKEENLKLKS ENQVLGQYIE NLMSASSVFQ

TTDTKSKRK
Length:159
Mass (Da):18,045
Last modified:May 20, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF0EDFE11873E9B0B
GO
Isoform 2 (identifier: Q9UIL1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-37: Missing.
     38-60: QLVQVSRPEVSAGSLLLPAPQAE → MDGSRKEEEEDSTFTNISLADDI

Show »
Length:122
Mass (Da):13,929
Checksum:i92BE3D1DE794E341
GO
Isoform 3 (identifier: Q9UIL1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-37: Missing.
     38-60: QLVQVSRPEVSAGSLLLPAPQAE → MDGSRKEEEEDSTFTNISLADDI
     85-85: Missing.

Show »
Length:121
Mass (Da):13,857
Checksum:iE1963D3A904C50EE
GO
Isoform 4 (identifier: Q9UIL1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     85-112: Missing.

Show »
Length:131
Mass (Da):14,801
Checksum:iB5B50B740CE13E7A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DGB0A0A0C4DGB0_HUMAN
Short coiled-coil protein
SCOC
82Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK01707 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence AAP97732 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti29 – 32GRSG → HEGR in AAK01707 (PubMed:11303027).Curated4
Sequence conflicti29 – 32GRSG → HEGR in AAP97732 (Ref. 6) Curated4
Isoform 2 (identifier: Q9UIL1-2)
Sequence conflicti14F → L in BAB55375 (PubMed:15815621).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0336421 – 37Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST37
Alternative sequenceiVSP_03364338 – 60QLVQV…APQAE → MDGSRKEEEEDSTFTNISLA DDI in isoform 2 and isoform 3. 2 PublicationsAdd BLAST23
Alternative sequenceiVSP_03364485 – 112Missing in isoform 4. 1 PublicationAdd BLAST28
Alternative sequenceiVSP_03364585Missing in isoform 3. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027797 mRNA Translation: BAB55375.1
AC093671 Genomic DNA No translation available.
AC114771 Genomic DNA No translation available.
CH471056 Genomic DNA Translation: EAX05102.1
CH471056 Genomic DNA Translation: EAX05104.1
CH471056 Genomic DNA Translation: EAX05103.1
BC016511 mRNA Translation: AAH16511.2
BC062684 mRNA Translation: AAH62684.1
AF330205 mRNA Translation: AAK01707.1 Different initiation.
AF448857 mRNA Translation: AAP97732.1 Different initiation.
AB015335 mRNA Translation: BAA88116.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3750.1 [Q9UIL1-2]
CCDS54806.1 [Q9UIL1-1]
CCDS54807.1 [Q9UIL1-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001146918.1, NM_001153446.1 [Q9UIL1-2]
NP_001146956.1, NM_001153484.1 [Q9UIL1-1]
NP_001147024.1, NM_001153552.1 [Q9UIL1-4]
NP_001147057.1, NM_001153585.1 [Q9UIL1-2]
NP_001147107.1, NM_001153635.1 [Q9UIL1-3]
NP_001147135.1, NM_001153663.1
NP_001147162.1, NM_001153690.1
NP_115936.2, NM_032547.2 [Q9UIL1-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000338517; ENSP00000345262; ENSG00000153130 [Q9UIL1-2]
ENST00000394203; ENSP00000377753; ENSG00000153130 [Q9UIL1-2]
ENST00000394205; ENSP00000377755; ENSG00000153130 [Q9UIL1-2]
ENST00000506597; ENSP00000426649; ENSG00000153130 [Q9UIL1-4]
ENST00000608372; ENSP00000477352; ENSG00000153130 [Q9UIL1-1]
ENST00000614192; ENSP00000477812; ENSG00000153130 [Q9UIL1-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
60592

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:60592

UCSC genome browser

More...
UCSCi
uc003iib.2 human [Q9UIL1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027797 mRNA Translation: BAB55375.1
AC093671 Genomic DNA No translation available.
AC114771 Genomic DNA No translation available.
CH471056 Genomic DNA Translation: EAX05102.1
CH471056 Genomic DNA Translation: EAX05104.1
CH471056 Genomic DNA Translation: EAX05103.1
BC016511 mRNA Translation: AAH16511.2
BC062684 mRNA Translation: AAH62684.1
AF330205 mRNA Translation: AAK01707.1 Different initiation.
AF448857 mRNA Translation: AAP97732.1 Different initiation.
AB015335 mRNA Translation: BAA88116.1
CCDSiCCDS3750.1 [Q9UIL1-2]
CCDS54806.1 [Q9UIL1-1]
CCDS54807.1 [Q9UIL1-4]
RefSeqiNP_001146918.1, NM_001153446.1 [Q9UIL1-2]
NP_001146956.1, NM_001153484.1 [Q9UIL1-1]
NP_001147024.1, NM_001153552.1 [Q9UIL1-4]
NP_001147057.1, NM_001153585.1 [Q9UIL1-2]
NP_001147107.1, NM_001153635.1 [Q9UIL1-3]
NP_001147135.1, NM_001153663.1
NP_001147162.1, NM_001153690.1
NP_115936.2, NM_032547.2 [Q9UIL1-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4BWDX-ray2.70A/B/C78-159[»]
SMRiQ9UIL1
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi121943, 34 interactors
IntActiQ9UIL1, 38 interactors
MINTiQ9UIL1
STRINGi9606.ENSP00000477352

PTM databases

iPTMnetiQ9UIL1
PhosphoSitePlusiQ9UIL1

Polymorphism and mutation databases

BioMutaiSCOC
DMDMi189046186

Proteomic databases

EPDiQ9UIL1
jPOSTiQ9UIL1
MassIVEiQ9UIL1
PaxDbiQ9UIL1
PeptideAtlasiQ9UIL1
PRIDEiQ9UIL1
ProteomicsDBi19156
84542 [Q9UIL1-1]
84543 [Q9UIL1-2]
84544 [Q9UIL1-3]
84545 [Q9UIL1-4]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
60592

Genome annotation databases

EnsembliENST00000338517; ENSP00000345262; ENSG00000153130 [Q9UIL1-2]
ENST00000394203; ENSP00000377753; ENSG00000153130 [Q9UIL1-2]
ENST00000394205; ENSP00000377755; ENSG00000153130 [Q9UIL1-2]
ENST00000506597; ENSP00000426649; ENSG00000153130 [Q9UIL1-4]
ENST00000608372; ENSP00000477352; ENSG00000153130 [Q9UIL1-1]
ENST00000614192; ENSP00000477812; ENSG00000153130 [Q9UIL1-1]
GeneIDi60592
KEGGihsa:60592
UCSCiuc003iib.2 human [Q9UIL1-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
60592
EuPathDBiHostDB:ENSG00000153130.17

GeneCards: human genes, protein and diseases

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GeneCardsi
SCOC
HGNCiHGNC:20335 SCOC
HPAiHPA061198
HPA070321
neXtProtiNX_Q9UIL1
OpenTargetsiENSG00000153130
PharmGKBiPA134972148

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3650 Eukaryota
ENOG4111R9Q LUCA
GeneTreeiENSGT00390000008828
InParanoidiQ9UIL1
KOiK20316
OMAiNCDIDAG
OrthoDBi1581498at2759
PhylomeDBiQ9UIL1
TreeFamiTF323340

Enzyme and pathway databases

ReactomeiR-HSA-6811440 Retrograde transport at the Trans-Golgi-Network

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SCOC human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
60592
PharosiQ9UIL1 Tbio

Protein Ontology

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PROi
PR:Q9UIL1
RNActiQ9UIL1 protein

Gene expression databases

BgeeiENSG00000153130 Expressed in 203 organ(s), highest expression level in lateral nuclear group of thalamus
ExpressionAtlasiQ9UIL1 baseline and differential
GenevisibleiQ9UIL1 HS

Family and domain databases

InterProiView protein in InterPro
IPR019357 SCOC
PANTHERiPTHR21614 PTHR21614, 1 hit
PfamiView protein in Pfam
PF10224 DUF2205, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCOC_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UIL1
Secondary accession number(s): B7WPH7
, D3DNY7, E9PB65, Q6P5T9, Q7L2Y0, Q7Z4P2, Q96JY9, Q9BZB2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 11, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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