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UniProtKB - Q9UHV9 (PFD2_HUMAN)

Entry version 178 (07 Apr 2021)
Sequence version 1 (01 May 2000)
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Protein

Prefoldin subunit 2

Gene

PFDN2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9UHV9

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-389957, Prefoldin mediated transfer of substrate to CCT/TriC

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Prefoldin subunit 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PFDN2
Synonyms:PFD2
ORF Names:HSPC231
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:8867, PFDN2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		613466, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9UHV9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000143256.4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Mitochondrion, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		5202

Open Targets

More...OpenTargetsi		ENSG00000143256

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA33208

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9UHV9, Tbio

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL4295976

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		PFDN2

Domain mapping of disease mutations (DMDM)

More...DMDMi		12643887

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001248351 – 154Prefoldin subunit 2Add BLAST154

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9UHV9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9UHV9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9UHV9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9UHV9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9UHV9

PeptideAtlas

More...PeptideAtlasi		Q9UHV9

PRoteomics IDEntifications database

More...PRIDEi		Q9UHV9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		84419

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q9UHV9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9UHV9

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q9UHV9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9UHV9

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9UHV9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000143256, Expressed in adenohypophysis and 239 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9UHV9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9UHV9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000143256, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to c-Myc; interacts with its N-terminal domain (By similarity). Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

Interacts with URI1; the interaction is phosphorylation-dependent and occurs in a growth-dependent manner.

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		111224, 126 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-6144, URI1 prefoldin co-chaperone complex
CPX-6149, Prefoldin co-chaperone complex

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9UHV9

Database of interacting proteins

More...DIPi		DIP-27557N

Protein interaction database and analysis system

More...IntActi		Q9UHV9, 88 interactors

Molecular INTeraction database

More...MINTi		Q9UHV9

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000356989

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9UHV9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9UHV9

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the prefoldin subunit beta family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4098, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000009272

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_113004_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9UHV9

Identification of Orthologs from Complete Genome Data

More...OMAi		DPERKCF

Database of Orthologous Groups

More...OrthoDBi		1564069at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9UHV9

TreeFam database of animal gene trees

More...TreeFami		TF313252

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.287.370, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR027235, PFD2
IPR002777, PFD_beta-like
IPR009053, Prefoldin

The PANTHER Classification System

More...PANTHERi		PTHR13303, PTHR13303, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01920, Prefoldin_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UHV9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAENSGRAGK SSGSGAGKGA VSAEQVIAGF NRLRQEQRGL ASKAAELEME 
        60         70         80         90        100
LNEHSLVIDT LKEVDETRKC YRMVGGVLVE RTVKEVLPAL ENNKEQIQKI 
       110        120        130        140        150
IETLTQQLQA KGKELNEFRE KHNIRLMGED EKPAAKENSE GAGAKASSAG 

VLVS
Length:154
Mass (Da):16,648
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2FC68A7425412198
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF36151 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti14 – 22SGAGKGAVS → TPRRGRGRCP in AAD47084 (Ref. 2) Curated9
Sequence conflicti15Missing in AAF36151 (PubMed:11042152).Curated1
Sequence conflicti29 – 34GFNRLR → SFNAF in AAF36151 (PubMed:11042152).Curated6

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF117237 mRNA Translation: AAF17218.1
AF165883 mRNA Translation: AAD47084.1
AF151065 mRNA Translation: AAF36151.1 Frameshift.
BC012464 mRNA Translation: AAH12464.1
BC047042 mRNA Translation: AAH47042.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS1217.1

NCBI Reference Sequences

More...RefSeqi		NP_036526.2, NM_012394.3
XP_011507926.1, XM_011509624.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000368010; ENSP00000356989; ENSG00000143256

Database of genes from NCBI RefSeq genomes

More...GeneIDi		5202

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:5202

UCSC genome browser

More...UCSCi		uc001fxu.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF117237 mRNA Translation: AAF17218.1
AF165883 mRNA Translation: AAD47084.1
AF151065 mRNA Translation: AAF36151.1 Frameshift.
BC012464 mRNA Translation: AAH12464.1
BC047042 mRNA Translation: AAH47042.1
CCDSiCCDS1217.1
RefSeqiNP_036526.2, NM_012394.3
XP_011507926.1, XM_011509624.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6NR8electron microscopy7.80222-124[»]
6NR9electron microscopy8.50222-124[»]
6NRBelectron microscopy8.70222-124[»]
6NRCelectron microscopy8.30222-124[»]
6NRDelectron microscopy8.20222-124[»]
SMRiQ9UHV9
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi111224, 126 interactors
ComplexPortaliCPX-6144, URI1 prefoldin co-chaperone complex
CPX-6149, Prefoldin co-chaperone complex
CORUMiQ9UHV9
DIPiDIP-27557N
IntActiQ9UHV9, 88 interactors
MINTiQ9UHV9
STRINGi9606.ENSP00000356989

Chemistry databases

ChEMBLiCHEMBL4295976

PTM databases

iPTMnetiQ9UHV9
MetOSiteiQ9UHV9
PhosphoSitePlusiQ9UHV9
SwissPalmiQ9UHV9

Genetic variation databases

BioMutaiPFDN2
DMDMi12643887

Proteomic databases

EPDiQ9UHV9
jPOSTiQ9UHV9
MassIVEiQ9UHV9
MaxQBiQ9UHV9
PaxDbiQ9UHV9
PeptideAtlasiQ9UHV9
PRIDEiQ9UHV9
ProteomicsDBi84419
TopDownProteomicsiQ9UHV9

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		34290, 170 antibodies

The DNASU plasmid repository

More...DNASUi		5202

Genome annotation databases

EnsembliENST00000368010; ENSP00000356989; ENSG00000143256
GeneIDi5202
KEGGihsa:5202
UCSCiuc001fxu.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		5202
DisGeNETi5202

GeneCards: human genes, protein and diseases

More...GeneCardsi		PFDN2
HGNCiHGNC:8867, PFDN2
HPAiENSG00000143256, Low tissue specificity
MIMi613466, gene
neXtProtiNX_Q9UHV9
OpenTargetsiENSG00000143256
PharmGKBiPA33208
VEuPathDBiHostDB:ENSG00000143256.4

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4098, Eukaryota
GeneTreeiENSGT00390000009272
HOGENOMiCLU_113004_0_0_1
InParanoidiQ9UHV9
OMAiDPERKCF
OrthoDBi1564069at2759
PhylomeDBiQ9UHV9
TreeFamiTF313252

Enzyme and pathway databases

PathwayCommonsiQ9UHV9
ReactomeiR-HSA-389957, Prefoldin mediated transfer of substrate to CCT/TriC

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		5202, 773 hits in 995 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		PFDN2, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		PFDN2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		5202
PharosiQ9UHV9, Tbio

Protein Ontology

More...PROi		PR:Q9UHV9
RNActiQ9UHV9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000143256, Expressed in adenohypophysis and 239 other tissues
ExpressionAtlasiQ9UHV9, baseline and differential
GenevisibleiQ9UHV9, HS

Family and domain databases

Gene3Di1.10.287.370, 1 hit
InterProiView protein in InterPro
IPR027235, PFD2
IPR002777, PFD_beta-like
IPR009053, Prefoldin
PANTHERiPTHR13303, PTHR13303, 1 hit
PfamiView protein in Pfam
PF01920, Prefoldin_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPFD2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UHV9
Secondary accession number(s): Q9P0P7, Q9UN05
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 1, 2000
Last modified: April 7, 2021
This is version 178 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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