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Entry version 171 (16 Oct 2019)
Sequence version 2 (01 Mar 2004)
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Protein

Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1

Gene

BAIAP2L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1
Short name:
BAI1-associated protein 2-like protein 1
Alternative name(s):
Insulin receptor tyrosine kinase substrate
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BAIAP2L1
Synonyms:IRTKS
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21649 BAIAP2L1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611877 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UHR4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi141K → E: Loss ability to induce the formation of actin clusters; when associated with K-142; R-145 and K-146. 1 Publication1
Mutagenesisi142K → E: Loss ability to induce the formation of actin clusters; when associated with K-141; R-145 and K-146. 1 Publication1
Mutagenesisi145R → E: Loss ability to induce the formation of actin clusters; when associated with K-141; K-142 and K-146. 1 Publication1
Mutagenesisi146K → E: Loss ability to induce the formation of actin clusters; when associated with K-141; K-142 and R-145. 1 Publication1
Mutagenesisi488 – 511Missing : Loss ability to induce the formation of actin clusters; induce the formation of long filopodia. 1 PublicationAdd BLAST24

Organism-specific databases

DisGeNET

More...
DisGeNETi
55971

Open Targets

More...
OpenTargetsi
ENSG00000006453

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672562

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UHR4

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
BAIAP2L1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74735022

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002478541 – 511Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1Add BLAST511

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei248PhosphothreonineCombined sources1
Modified residuei257PhosphothreonineCombined sources1
Modified residuei261PhosphoserineCombined sources1
Modified residuei281PhosphoserineCombined sources1
Modified residuei331PhosphoserineCombined sources1
Modified residuei354PhosphoserineCombined sources1
Modified residuei412PhosphothreonineCombined sources1
Modified residuei414PhosphoserineCombined sources1
Modified residuei420PhosphoserineCombined sources1
Modified residuei422PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated on tyrosine in response to insulin.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UHR4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UHR4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UHR4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UHR4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UHR4

PeptideAtlas

More...
PeptideAtlasi
Q9UHR4

PRoteomics IDEntifications database

More...
PRIDEi
Q9UHR4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
84402

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UHR4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UHR4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000006453 Expressed in 200 organ(s), highest expression level in tendon of biceps brachii

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UHR4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA019484
HPA021257
HPA023874
HPA029503

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RAC1. Binds to F-actin.

Interacts with FASLG.

Interacts (via SH3 domain) with E.coli effector protein EspF(U) (via PXXP motifs).

Identified in a complex containing at least WASL, BAIAP2L1 and E.coli EspF(U).

Interacts with E.coli intimin receptor Tir.

5 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121017, 46 interactors

Database of interacting proteins

More...
DIPi
DIP-53820N

Protein interaction database and analysis system

More...
IntActi
Q9UHR4, 47 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000005260

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1511
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UHR4

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 249IMDPROSITE-ProRule annotationAdd BLAST249
Domaini339 – 402SH3PROSITE-ProRule annotationAdd BLAST64

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni483 – 511Binds F-actinAdd BLAST29

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili115 – 154Sequence analysisAdd BLAST40

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The IMD domain is predicted to have a helical structure. It may induce actin bundling and filopodia formation (By similarity).By similarity

Keywords - Domaini

Coiled coil, SH3 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGQC Eukaryota
ENOG410Y6FF LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153560

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UHR4

KEGG Orthology (KO)

More...
KOi
K20127

Identification of Orthologs from Complete Genome Data

More...
OMAi
RWQETCC

Database of Orthologous Groups

More...
OrthoDBi
457637at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UHR4

TreeFam database of animal gene trees

More...
TreeFami
TF325648

Family and domain databases

Conserved Domains Database

More...
CDDi
cd11913 SH3_BAIAP2L1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1270.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR013606 I-BAR_dom
IPR027681 IRSp53/IRTKS/Pinkbar
IPR030060 IRTKS
IPR035592 IRTKS_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain

The PANTHER Classification System

More...
PANTHERi
PTHR14206 PTHR14206, 1 hit
PTHR14206:SF4 PTHR14206:SF4, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF08397 IMD, 1 hit
PF14604 SH3_9, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00326 SH3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103657 SSF103657, 1 hit
SSF50044 SSF50044, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51338 IMD, 1 hit
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UHR4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRGPEEVNR LTESTYRNVM EQFNPGLRNL INLGKNYEKA VNAMILAGKA
60 70 80 90 100
YYDGVAKIGE IATGSPVSTE LGHVLIEISS THKKLNESLD ENFKKFHKEI
110 120 130 140 150
IHELEKKIEL DVKYMNATLK RYQTEHKNKL ESLEKSQAEL KKIRRKSQGS
160 170 180 190 200
RNALKYEHKE IEYVETVTSR QSEIQKFIAD GCKEALLEEK RRFCFLVDKH
210 220 230 240 250
CGFANHIHYY HLQSAELLNS KLPRWQETCV DAIKVPEKIM NMIEEIKTPA
260 270 280 290 300
STPVSGTPQA SPMIERSNVV RKDYDTLSKC SPKMPPAPSG RAYTSPLIDM
310 320 330 340 350
FNNPATAAPN SQRVNNSTGT SEDPSLQRSV SVATGLNMMK KQKVKTIFPH
360 370 380 390 400
TAGSNKTLLS FAQGDVITLL IPEEKDGWLY GEHDVSKARG WFPSSYTKLL
410 420 430 440 450
EENETEAVTV PTPSPTPVRS ISTVNLSENS SVVIPPPDYL ECLSMGAAAD
460 470 480 490 500
RRADSARTTS TFKAPASKPE TAAPNDANGT AKPPFLSGEN PFATVKLRPT
510
VTNDRSAPII R
Length:511
Mass (Da):56,883
Last modified:March 1, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC2304C4444B02F02
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD20937 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAS07549 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB15671 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti456A → V in BAB15671 (PubMed:14702039).Curated1
Sequence conflicti460S → F in BAB15671 (PubMed:14702039).Curated1
Sequence conflicti464A → V in BAB15671 (PubMed:14702039).Curated1
Sequence conflicti466A → V in BAB15671 (PubMed:14702039).Curated1
Sequence conflicti467S → F in BAB15671 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_033515460S → T. Corresponds to variant dbSNP:rs2269966Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF119666 mRNA Translation: AAF17223.2
AC004841 Genomic DNA Translation: AAD20937.1 Sequence problems.
AC093169 Genomic DNA No translation available.
AC093799 Genomic DNA Translation: AAS07549.1 Different initiation.
AC093799 Genomic DNA Translation: AAS07550.1
CH236956 Genomic DNA Translation: EAL23890.1
CH471091 Genomic DNA Translation: EAW76706.1
BC013888 mRNA Translation: AAH13888.1
AK027142 mRNA Translation: BAB15671.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34687.1

NCBI Reference Sequences

More...
RefSeqi
NP_061330.2, NM_018842.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000005260; ENSP00000005260; ENSG00000006453

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55971

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55971

UCSC genome browser

More...
UCSCi
uc003upj.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF119666 mRNA Translation: AAF17223.2
AC004841 Genomic DNA Translation: AAD20937.1 Sequence problems.
AC093169 Genomic DNA No translation available.
AC093799 Genomic DNA Translation: AAS07549.1 Different initiation.
AC093799 Genomic DNA Translation: AAS07550.1
CH236956 Genomic DNA Translation: EAL23890.1
CH471091 Genomic DNA Translation: EAW76706.1
BC013888 mRNA Translation: AAH13888.1
AK027142 mRNA Translation: BAB15671.1 Different initiation.
CCDSiCCDS34687.1
RefSeqiNP_061330.2, NM_018842.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KXCNMR-A339-402[»]
2LNHNMR-B339-402[»]
SMRiQ9UHR4
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi121017, 46 interactors
DIPiDIP-53820N
IntActiQ9UHR4, 47 interactors
STRINGi9606.ENSP00000005260

PTM databases

iPTMnetiQ9UHR4
PhosphoSitePlusiQ9UHR4

Polymorphism and mutation databases

BioMutaiBAIAP2L1
DMDMi74735022

Proteomic databases

EPDiQ9UHR4
jPOSTiQ9UHR4
MassIVEiQ9UHR4
MaxQBiQ9UHR4
PaxDbiQ9UHR4
PeptideAtlasiQ9UHR4
PRIDEiQ9UHR4
ProteomicsDBi84402

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55971

Genome annotation databases

EnsembliENST00000005260; ENSP00000005260; ENSG00000006453
GeneIDi55971
KEGGihsa:55971
UCSCiuc003upj.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55971
DisGeNETi55971

GeneCards: human genes, protein and diseases

More...
GeneCardsi
BAIAP2L1
HGNCiHGNC:21649 BAIAP2L1
HPAiHPA019484
HPA021257
HPA023874
HPA029503
MIMi611877 gene
neXtProtiNX_Q9UHR4
OpenTargetsiENSG00000006453
PharmGKBiPA142672562

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IGQC Eukaryota
ENOG410Y6FF LUCA
GeneTreeiENSGT00940000153560
InParanoidiQ9UHR4
KOiK20127
OMAiRWQETCC
OrthoDBi457637at2759
PhylomeDBiQ9UHR4
TreeFamiTF325648

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
BAIAP2L1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
BAIAP2L1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55971
PharosiQ9UHR4

Protein Ontology

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PROi
PR:Q9UHR4

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000006453 Expressed in 200 organ(s), highest expression level in tendon of biceps brachii
GenevisibleiQ9UHR4 HS

Family and domain databases

CDDicd11913 SH3_BAIAP2L1, 1 hit
Gene3Di1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR013606 I-BAR_dom
IPR027681 IRSp53/IRTKS/Pinkbar
IPR030060 IRTKS
IPR035592 IRTKS_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR14206 PTHR14206, 1 hit
PTHR14206:SF4 PTHR14206:SF4, 1 hit
PfamiView protein in Pfam
PF08397 IMD, 1 hit
PF14604 SH3_9, 1 hit
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS51338 IMD, 1 hit
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBI2L1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UHR4
Secondary accession number(s): A4D268
, Q75L21, Q75L22, Q96CV4, Q9H5F5, Q9Y2M8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: March 1, 2004
Last modified: October 16, 2019
This is version 171 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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