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Entry version 132 (08 May 2019)
Sequence version 1 (01 May 2000)
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Protein

Nuclear prelamin A recognition factor

Gene

NARF

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • lamin binding Source: HGNC

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nuclear prelamin A recognition factor
Alternative name(s):
Iron-only hydrogenase-like protein 2
Short name:
IOP2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NARF
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:29916 NARF

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605349 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UHQ1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000141562

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671294

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NARF

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74735021

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002884791 – 456Nuclear prelamin A recognition factorAdd BLAST456

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei29PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9UHQ1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UHQ1

PeptideAtlas

More...
PeptideAtlasi
Q9UHQ1

PRoteomics IDEntifications database

More...
PRIDEi
Q9UHQ1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84396
84397 [Q9UHQ1-2]
84398 [Q9UHQ1-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UHQ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UHQ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous. Predominantly expressed in skeletal muscle, heart and brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000141562 Expressed in 220 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9UHQ1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UHQ1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053006

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with LMNA and binds to the farnesylated C-terminal domain.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117709, 21 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UHQ1, 15 interactors

Molecular INTeraction database

More...
MINTi
Q9UHQ1

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000309899

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NARF family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2439 Eukaryota
COG4624 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153514

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000191744

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UHQ1

Database of Orthologous Groups

More...
OrthoDBi
705416at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UHQ1

TreeFam database of animal gene trees

More...
TreeFami
TF106273

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009016 Fe_hydrogenase
IPR004108 Fe_hydrogenase_lsu_C
IPR003149 Fe_hydrogenase_ssu

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02906 Fe_hyd_lg_C, 1 hit
PF02256 Fe_hyd_SSU, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00902 Fe_hyd_SSU, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53920 SSF53920, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 13 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UHQ1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKCEHCTRKE CSKKTKTDDQ ENVSADAPSP AQENGEKGEF HKLADAKIFL
60 70 80 90 100
SDCLACDSCM TAEEGVQLSQ QNAKDFFRVL NLNKKCDTSK HKVLVVSVCP
110 120 130 140 150
QSLPYFAAKF NLSVTDASRR LCGFLKSLGV HYVFDTTIAA DFSILESQKE
160 170 180 190 200
FVRRYRQHSE EERTLPMLTS ACPGWVRYAE RVLGRPITAH LCTAKSPQQV
210 220 230 240 250
MGSLVKDYFA RQQNLSPEKI FHVIVAPCYD KKLEALQESL PPALHGSRGA
260 270 280 290 300
DCVLTSGEIA QIMEQGDLSV RDAAVDTLFG DLKEDKVTRH DGASSDGHLA
310 320 330 340 350
HIFRHAAKEL FNEDVEEVTY RALRNKDFQE VTLEKNGEVV LRFAAAYGFR
360 370 380 390 400
NIQNMILKLK KGKFPFHFVE VLACAGGCLN GRGQAQTPDG HADKALLRQM
410 420 430 440 450
EGIYADIPVR RPESSAHVQE LYQEWLEGIN SPKAREVLHT TYQSQERGTH

SLDIKW
Length:456
Mass (Da):51,156
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF615D812E7FC7D0F
GO
Isoform 2 (identifier: Q9UHQ1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     256-256: S → SEISQAWWCTPVITATREAAARESLEPGRQRLQRDKIAPLDSSLGGG

Show »
Length:502
Mass (Da):56,161
Checksum:i79A6F299C2CAAEF1
GO
Isoform 3 (identifier: Q9UHQ1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     38-85: Missing.

Show »
Length:408
Mass (Da):45,796
Checksum:i42AD67C382D83D7C
GO
Isoform 4 (identifier: Q9UHQ1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-59: Missing.

Note: No experimental confirmation available.
Show »
Length:397
Mass (Da):44,681
Checksum:iF7CC7AE3834362FA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EP87E7EP87_HUMAN
Nuclear prelamin A recognition fact...
NARF
502Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A088AWN8A0A088AWN8_HUMAN
Nuclear prelamin A recognition fact...
NARF
503Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KT43J3KT43_HUMAN
Nuclear prelamin A recognition fact...
NARF
262Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PH27E9PH27_HUMAN
Nuclear prelamin A recognition fact...
NARF
262Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KRH7J3KRH7_HUMAN
Nuclear prelamin A recognition fact...
NARF
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KS48J3KS48_HUMAN
Nuclear prelamin A recognition fact...
NARF
217Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KTP5J3KTP5_HUMAN
Nuclear prelamin A recognition fact...
NARF
143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QLT6J3QLT6_HUMAN
Nuclear prelamin A recognition fact...
NARF
99Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QRB0J3QRB0_HUMAN
Nuclear prelamin A recognition fact...
NARF
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KTG5J3KTG5_HUMAN
Nuclear prelamin A recognition fact...
NARF
167Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti154R → L in BAG51834 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0463711 – 59Missing in isoform 4. 1 PublicationAdd BLAST59
Alternative sequenceiVSP_02569138 – 85Missing in isoform 3. 1 PublicationAdd BLAST48
Alternative sequenceiVSP_025690256S → SEISQAWWCTPVITATREAA ARESLEPGRQRLQRDKIAPL DSSLGGG in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF128406 mRNA Translation: AAD51446.1
AK000929 mRNA Translation: BAA91432.1
AK056966 mRNA Translation: BAG51834.1
AC124287 Genomic DNA No translation available.
AC132938 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89794.1
CH471099 Genomic DNA Translation: EAW89798.1
BC000438 mRNA Translation: AAH00438.1
BC016440 mRNA Translation: AAH16440.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32777.1 [Q9UHQ1-1]
CCDS42403.1 [Q9UHQ1-3]
CCDS42404.1 [Q9UHQ1-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001033707.1, NM_001038618.2 [Q9UHQ1-4]
NP_001077077.1, NM_001083608.1 [Q9UHQ1-3]
NP_036468.1, NM_012336.3 [Q9UHQ1-1]
NP_114174.1, NM_031968.2 [Q9UHQ1-2]
XP_005256397.1, XM_005256340.3 [Q9UHQ1-4]
XP_011521843.1, XM_011523541.2 [Q9UHQ1-4]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000309794; ENSP00000309899; ENSG00000141562 [Q9UHQ1-1]
ENST00000345415; ENSP00000283996; ENSG00000141562 [Q9UHQ1-3]
ENST00000390006; ENSP00000374656; ENSG00000141562 [Q9UHQ1-4]

Database of genes from NCBI RefSeq genomes

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GeneIDi
26502

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:26502

UCSC genome browser

More...
UCSCi
uc002kff.5 human [Q9UHQ1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF128406 mRNA Translation: AAD51446.1
AK000929 mRNA Translation: BAA91432.1
AK056966 mRNA Translation: BAG51834.1
AC124287 Genomic DNA No translation available.
AC132938 Genomic DNA No translation available.
CH471099 Genomic DNA Translation: EAW89794.1
CH471099 Genomic DNA Translation: EAW89798.1
BC000438 mRNA Translation: AAH00438.1
BC016440 mRNA Translation: AAH16440.1
CCDSiCCDS32777.1 [Q9UHQ1-1]
CCDS42403.1 [Q9UHQ1-3]
CCDS42404.1 [Q9UHQ1-4]
RefSeqiNP_001033707.1, NM_001038618.2 [Q9UHQ1-4]
NP_001077077.1, NM_001083608.1 [Q9UHQ1-3]
NP_036468.1, NM_012336.3 [Q9UHQ1-1]
NP_114174.1, NM_031968.2 [Q9UHQ1-2]
XP_005256397.1, XM_005256340.3 [Q9UHQ1-4]
XP_011521843.1, XM_011523541.2 [Q9UHQ1-4]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi117709, 21 interactors
IntActiQ9UHQ1, 15 interactors
MINTiQ9UHQ1
STRINGi9606.ENSP00000309899

PTM databases

iPTMnetiQ9UHQ1
PhosphoSitePlusiQ9UHQ1

Polymorphism and mutation databases

BioMutaiNARF
DMDMi74735021

Proteomic databases

jPOSTiQ9UHQ1
PaxDbiQ9UHQ1
PeptideAtlasiQ9UHQ1
PRIDEiQ9UHQ1
ProteomicsDBi84396
84397 [Q9UHQ1-2]
84398 [Q9UHQ1-3]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
26502
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000309794; ENSP00000309899; ENSG00000141562 [Q9UHQ1-1]
ENST00000345415; ENSP00000283996; ENSG00000141562 [Q9UHQ1-3]
ENST00000390006; ENSP00000374656; ENSG00000141562 [Q9UHQ1-4]
GeneIDi26502
KEGGihsa:26502
UCSCiuc002kff.5 human [Q9UHQ1-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
26502

GeneCards: human genes, protein and diseases

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GeneCardsi
NARF
HGNCiHGNC:29916 NARF
HPAiHPA053006
MIMi605349 gene
neXtProtiNX_Q9UHQ1
OpenTargetsiENSG00000141562
PharmGKBiPA142671294

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2439 Eukaryota
COG4624 LUCA
GeneTreeiENSGT00940000153514
HOGENOMiHOG000191744
InParanoidiQ9UHQ1
OrthoDBi705416at2759
PhylomeDBiQ9UHQ1
TreeFamiTF106273

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
NARF

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
26502

Protein Ontology

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PROi
PR:Q9UHQ1

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000141562 Expressed in 220 organ(s), highest expression level in blood
ExpressionAtlasiQ9UHQ1 baseline and differential
GenevisibleiQ9UHQ1 HS

Family and domain databases

InterProiView protein in InterPro
IPR009016 Fe_hydrogenase
IPR004108 Fe_hydrogenase_lsu_C
IPR003149 Fe_hydrogenase_ssu
PfamiView protein in Pfam
PF02906 Fe_hyd_lg_C, 1 hit
PF02256 Fe_hyd_SSU, 1 hit
SMARTiView protein in SMART
SM00902 Fe_hyd_SSU, 1 hit
SUPFAMiSSF53920 SSF53920, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNARF_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UHQ1
Secondary accession number(s): A6NCJ3
, B3KPX2, K4DI98, Q96AY9, Q9BWC6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 1, 2000
Last modified: May 8, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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