Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 181 (03 Jul 2019)
Sequence version 2 (18 Apr 2006)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Septin-9

Gene

SEPTIN9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.By similarityCurated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei339GTPBy similarity1
Binding sitei365GTP; via amide nitrogenBy similarity1
Binding sitei501GTP; via amide nitrogen and carbonyl oxygenBy similarity1
Binding sitei516GTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi305 – 312GTPBy similarity8
Nucleotide bindingi445 – 453GTPBy similarity9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q9UHD8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Septin-9
Alternative name(s):
MLL septin-like fusion protein MSF-A
Short name:
MLL septin-like fusion protein
Ovarian/Breast septin
Short name:
Ov/Br septin
Septin D1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SEPTIN9Imported
Synonyms:KIAA0991, MSF, SEPT9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7323 SEPTIN9

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604061 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UHD8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

A chromosomal aberration involving SEPTIN9/MSF is found in therapy-related acute myeloid leukemia (t-AML). Translocation t(11;17)(q23;q25) with KMT2A/MLL1.1 Publication
Hereditary neuralgic amyotrophy (HNA)4 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAutosomal dominant form of recurrent focal neuropathy characterized clinically by acute, recurrent episodes of brachial plexus neuropathy with muscle weakness and atrophy preceded by severe pain in the affected arm. HNA is triggered by environmental factors such as infection or parturition.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_033101106R → W in HNA. 4 PublicationsCorresponds to variant dbSNP:rs80338761Ensembl.1
Natural variantiVAR_033102111S → F in HNA. 3 PublicationsCorresponds to variant dbSNP:rs80338762Ensembl.1

Keywords - Diseasei

Disease mutation

Organism-specific databases

DisGeNET

More...
DisGeNETi
10801

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
SEPT9

MalaCards human disease database

More...
MalaCardsi
SEPT9
MIMi162100 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000184640

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
2901 Neuralgic amyotrophy

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31132

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL4105891

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SEPT9

Domain mapping of disease mutations (DMDM)

More...
DMDMi
93141311

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001735351 – 586Septin-9Add BLAST586

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei22PhosphoserineCombined sources1
Modified residuei30PhosphoserineCombined sources1
Modified residuei38PhosphothreonineCombined sources1
Modified residuei42PhosphothreonineCombined sources1
Modified residuei49PhosphothreonineCombined sources1
Modified residuei62N6-acetyllysineBy similarity1
Modified residuei82PhosphoserineCombined sources1
Modified residuei85PhosphoserineCombined sources1
Modified residuei89PhosphoserineCombined sources1
Modified residuei96PhosphoserineCombined sources1
Modified residuei142PhosphothreonineCombined sources1
Modified residuei278PhosphotyrosineCombined sources1
Modified residuei327PhosphoserineCombined sources1
Modified residuei332PhosphoserineCombined sources1
Isoform 3 (identifier: Q9UHD8-3)
Modified residuei1N-acetylmethionineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UHD8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UHD8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UHD8

PeptideAtlas

More...
PeptideAtlasi
Q9UHD8

PRoteomics IDEntifications database

More...
PRIDEi
Q9UHD8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84325
84326 [Q9UHD8-2]
84327 [Q9UHD8-3]
84328 [Q9UHD8-4]
84329 [Q9UHD8-5]
84330 [Q9UHD8-7]
84331 [Q9UHD8-8]
84332 [Q9UHD8-9]

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q9UHD8

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UHD8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UHD8

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9UHD8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues.4 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000184640 Expressed in 231 organ(s), highest expression level in parotid gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UHD8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UHD8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042564
HPA050627

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Septins polymerize into heterooligomeric protein complexes that form filaments, and associate with cellular membranes, actin filaments, and microtubules. GTPase activity is required for filament formation.

Interacts with SEPTIN2, SEPTIN6, SEPTIN7, SEPTIN11 and SEPTIN14.

Interacts with RTKN and ARHGEF18. In a mesenchymal cell line, Rho/RTKN signals cause disruption of wild-type septin filaments, but not of those containing isoform 2 variants HNA Trp-106 and Phe-111. In a mesenchymal cell line, isoform 2 variants HNA Trp-106 and Phe-111, but not wild type, form filaments with SEPTIN4.

6 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116015, 82 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9UHD8

Database of interacting proteins

More...
DIPi
DIP-36697N

Protein interaction database and analysis system

More...
IntActi
Q9UHD8, 40 interactors

Molecular INTeraction database

More...
MINTi
Q9UHD8

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000391249

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1586
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UHD8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini295 – 567Septin-type GPROSITE-ProRule annotationAdd BLAST273

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni305 – 312G1 motifPROSITE-ProRule annotation8
Regioni362 – 365G3 motifPROSITE-ProRule annotation4
Regioni444 – 447G4 motifPROSITE-ProRule annotation4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.PROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1547 Eukaryota
COG5019 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157195

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UHD8

KEGG Orthology (KO)

More...
KOi
K16938

Identification of Orthologs from Complete Genome Data

More...
OMAi
KSHAGEF

Database of Orthologous Groups

More...
OrthoDBi
188544at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UHD8

TreeFam database of animal gene trees

More...
TreeFami
TF101078

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01850 CDC_Septin, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
IPR030645 SEPT9
IPR016491 Septin

The PANTHER Classification System

More...
PANTHERi
PTHR18884:SF47 PTHR18884:SF47, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00735 Septin, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF006698 Septin, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51719 G_SEPTIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (8+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 8 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: There are potentially 18 isoforms.

This entry has 8 described isoforms and 23 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UHD8-1) [UniParc]FASTAAdd to basket
Also known as: Epsilon, MSF-A

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKKSYSGGTR TSSGRLRRLG DSSGPALKRS FEVEEVETPN STPPRRVQTP
60 70 80 90 100
LLRATVASST QKFQDLGVKN SEPSARHVDS LSQRSPKASL RRVELSGPKA
110 120 130 140 150
AEPVSRRTEL SIDISSKQVE NAGAIGPSRF GLKRAEVLGH KTPEPAPRRT
160 170 180 190 200
EITIVKPQES AHRRMEPPAS KVPEVPTAPA TDAAPKRVEI QMPKPAEAPT
210 220 230 240 250
APSPAQTLEN SEPAPVSQLQ SRLEPKPQPP VAEATPRSQE ATEAAPSCVG
260 270 280 290 300
DMADTPRDAG LKQAPASRNE KAPVDFGYVG IDSILEQMRR KAMKQGFEFN
310 320 330 340 350
IMVVGQSGLG KSTLINTLFK SKISRKSVQP TSEERIPKTI EIKSITHDIE
360 370 380 390 400
EKGVRMKLTV IDTPGFGDHI NNENCWQPIM KFINDQYEKY LQEEVNINRK
410 420 430 440 450
KRIPDTRVHC CLYFIPATGH SLRPLDIEFM KRLSKVVNIV PVIAKADTLT
460 470 480 490 500
LEERVHFKQR ITADLLSNGI DVYPQKEFDE DSEDRLVNEK FREMIPFAVV
510 520 530 540 550
GSDHEYQVNG KRILGRKTKW GTIEVENTTH CEFAYLRDLL IRTHMQNIKD
560 570 580
ITSSIHFEAY RVKRLNEGSS AMANGMEEKE PEAPEM
Length:586
Mass (Da):65,401
Last modified:April 18, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4404578328CFCFE
GO
Isoform 2 (identifier: Q9UHD8-2) [UniParc]FASTAAdd to basket
Also known as: Alpha

The sequence of this isoform differs from the canonical sequence as follows:
     1-25: MKKSYSGGTRTSSGRLRRLGDSSGP → MERDRIS

Show »
Length:568
Mass (Da):63,666
Checksum:i47A03DD79B5D6147
GO
Isoform 3 (identifier: Q9UHD8-3) [UniParc]FASTAAdd to basket
Also known as: Beta, MSF-B

The sequence of this isoform differs from the canonical sequence as follows:
     1-164: Missing.

Show »
Length:422
Mass (Da):47,501
Checksum:iF581FB2EA1A6E063
GO
Isoform 4 (identifier: Q9UHD8-4) [UniParc]FASTAAdd to basket
Also known as: Delta

The sequence of this isoform differs from the canonical sequence as follows:
     1-251: Missing.

Show »
Length:335
Mass (Da):38,518
Checksum:i82375B44AEFFC64C
GO
Isoform 5 (identifier: Q9UHD8-5) [UniParc]FASTAAdd to basket
Also known as: Gamma

The sequence of this isoform differs from the canonical sequence as follows:
     1-25: MKKSYSGGTRTSSGRLRRLGDSSGP → MSDPAVNAQLDGIISDFE

Show »
Length:579
Mass (Da):64,682
Checksum:iF176A071496AC44C
GO
Isoform 7 (identifier: Q9UHD8-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     7-25: Missing.

Note: No experimental confirmation available.
Show »
Length:567
Mass (Da):63,502
Checksum:i73741167A05AA0E1
GO
Isoform 8 (identifier: Q9UHD8-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-112: Missing.
     113-240: DISSKQVENA...VAEATPRSQE → MGSSFWEGLQ...CLATIGSDRQ

Note: No experimental confirmation available.
Show »
Length:474
Mass (Da):52,913
Checksum:i5B5DCF81F2D1A597
GO
Isoform 9 (identifier: Q9UHD8-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-224: Missing.
     225-240: PKPQPPVAEATPRSQE → MAGAGCTGTWSWLWGT

Note: No experimental confirmation available.
Show »
Length:362
Mass (Da):41,187
Checksum:i5530A4184F432A5C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 23 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7ER14K7ER14_HUMAN
Septin 9
SEPTIN9
159Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EJL9K7EJL9_HUMAN
Septin 9
SEPTIN9
189Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EPY1K7EPY1_HUMAN
Septin 9
SEPTIN9
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ENL0K7ENL0_HUMAN
Septin 9
SEPTIN9
152Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EK18K7EK18_HUMAN
Septin 9
SEPTIN9
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ELJ9K7ELJ9_HUMAN
Septin 9
SEPTIN9
144Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ENQ5K7ENQ5_HUMAN
Septin 9
SEPTIN9
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQD7K7EQD7_HUMAN
Septin 9
SEPTIN9
165Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ER52K7ER52_HUMAN
Septin 9
SEPTIN9
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EIE4K7EIE4_HUMAN
Septin 9
SEPTIN9
157Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB14057 differs from that shown. Aberrant splicing.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti251D → G in BAG64494 (PubMed:14702039).Curated1
Sequence conflicti487V → E in BAB14057 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02066776R → C1 PublicationCorresponds to variant dbSNP:rs202079794Ensembl.1
Natural variantiVAR_033101106R → W in HNA. 4 PublicationsCorresponds to variant dbSNP:rs80338761Ensembl.1
Natural variantiVAR_033102111S → F in HNA. 3 PublicationsCorresponds to variant dbSNP:rs80338762Ensembl.1
Natural variantiVAR_020668145P → L3 PublicationsCorresponds to variant dbSNP:rs34587622Ensembl.1
Natural variantiVAR_020669576M → V10 PublicationsCorresponds to variant dbSNP:rs2627223Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0123351 – 251Missing in isoform 4. 2 PublicationsAdd BLAST251
Alternative sequenceiVSP_0383151 – 224Missing in isoform 9. 1 PublicationAdd BLAST224
Alternative sequenceiVSP_0123361 – 164Missing in isoform 3. 4 PublicationsAdd BLAST164
Alternative sequenceiVSP_0383161 – 112Missing in isoform 8. 1 PublicationAdd BLAST112
Alternative sequenceiVSP_0123371 – 25MKKSY…DSSGP → MERDRIS in isoform 2. 5 PublicationsAdd BLAST25
Alternative sequenceiVSP_0123381 – 25MKKSY…DSSGP → MSDPAVNAQLDGIISDFE in isoform 5. 2 PublicationsAdd BLAST25
Alternative sequenceiVSP_0383177 – 25Missing in isoform 7. 1 PublicationAdd BLAST19
Alternative sequenceiVSP_038318113 – 240DISSK…PRSQE → MGSSFWEGLQVAVGLPQGCW PQGLDSGEPAEGGQLEAAPV CIVTRQSKETAGPTLGRGGW RQGSLRRGKGTSCRCRQLSP GHGPGRLTGCGECHRLPCRG LVSGFTGLRGQEEDDLAFCL ATIGSDRQ in isoform 8. 1 PublicationAdd BLAST128
Alternative sequenceiVSP_038319225 – 240PKPQP…PRSQE → MAGAGCTGTWSWLWGT in isoform 9. 1 PublicationAdd BLAST16

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF123052 mRNA Translation: AAD39749.1
AJ312319 mRNA Translation: CAC42221.1
AJ312320 mRNA Translation: CAC42222.1
AJ312321 mRNA Translation: CAC42223.1
AJ312322 mRNA Translation: CAC42224.1
AF189712 mRNA Translation: AAF23373.1
AF189713 mRNA Translation: AAF23374.1
AF142408 mRNA Translation: AAG27919.1
AK022493 mRNA Translation: BAB14057.1 Sequence problems.
AK290368 mRNA Translation: BAF83057.1
AK056495 mRNA Translation: BAG51732.1
AK300270 mRNA Translation: BAG62031.1
AK303449 mRNA Translation: BAG64494.1
AK304143 mRNA Translation: BAG65036.1
AK299828 mRNA Translation: BAH13140.1
AK316473 mRNA Translation: BAH14844.1
BT007215 mRNA Translation: AAP35879.1
CH471099 Genomic DNA Translation: EAW89462.1
CH471099 Genomic DNA Translation: EAW89463.1
CH471099 Genomic DNA Translation: EAW89468.1
BC021192 mRNA Translation: AAH21192.1
BC054004 mRNA Translation: AAH54004.1
AB023208 mRNA Translation: BAA76835.2
AL080131 mRNA Translation: CAB45728.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45790.1 [Q9UHD8-1]
CCDS45791.1 [Q9UHD8-2]
CCDS45792.1 [Q9UHD8-5]
CCDS45793.1 [Q9UHD8-3]
CCDS45794.1 [Q9UHD8-8]
CCDS45795.1 [Q9UHD8-4]
CCDS74166.1 [Q9UHD8-9]
CCDS77122.1 [Q9UHD8-7]

Protein sequence database of the Protein Information Resource

More...
PIRi
T12519

NCBI Reference Sequences

More...
RefSeqi
NP_001106963.1, NM_001113491.1 [Q9UHD8-1]
NP_001106964.1, NM_001113492.1 [Q9UHD8-3]
NP_001106965.1, NM_001113493.1 [Q9UHD8-5]
NP_001106966.1, NM_001113494.1 [Q9UHD8-3]
NP_001106967.1, NM_001113495.1 [Q9UHD8-8]
NP_001106968.1, NM_001113496.1 [Q9UHD8-4]
NP_001280624.1, NM_001293695.1 [Q9UHD8-7]
NP_001280625.1, NM_001293696.1 [Q9UHD8-9]
NP_001280626.1, NM_001293697.1 [Q9UHD8-4]
NP_001280627.1, NM_001293698.1 [Q9UHD8-4]
NP_006631.2, NM_006640.4 [Q9UHD8-2]
XP_005257019.1, XM_005256962.1
XP_006721706.1, XM_006721643.2
XP_006721707.1, XM_006721644.1
XP_011522509.1, XM_011524207.1
XP_011522510.1, XM_011524208.2
XP_016879520.1, XM_017024031.1
XP_016879521.1, XM_017024032.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000329047; ENSP00000329161; ENSG00000184640 [Q9UHD8-2]
ENST00000423034; ENSP00000405877; ENSG00000184640 [Q9UHD8-5]
ENST00000427177; ENSP00000391249; ENSG00000184640 [Q9UHD8-1]
ENST00000427180; ENSP00000415624; ENSG00000184640 [Q9UHD8-8]
ENST00000427674; ENSP00000403194; ENSG00000184640 [Q9UHD8-3]
ENST00000431235; ENSP00000406987; ENSG00000184640 [Q9UHD8-3]
ENST00000449803; ENSP00000400181; ENSG00000184640 [Q9UHD8-3]
ENST00000541152; ENSP00000438089; ENSG00000184640 [Q9UHD8-4]
ENST00000585930; ENSP00000468120; ENSG00000184640 [Q9UHD8-9]
ENST00000588690; ENSP00000468668; ENSG00000184640 [Q9UHD8-3]
ENST00000590294; ENSP00000465464; ENSG00000184640 [Q9UHD8-2]
ENST00000591088; ENSP00000466247; ENSG00000184640 [Q9UHD8-4]
ENST00000591198; ENSP00000468406; ENSG00000184640 [Q9UHD8-7]
ENST00000592951; ENSP00000466648; ENSG00000184640 [Q9UHD8-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10801

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10801

UCSC genome browser

More...
UCSCi
uc002jts.5 human [Q9UHD8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF123052 mRNA Translation: AAD39749.1
AJ312319 mRNA Translation: CAC42221.1
AJ312320 mRNA Translation: CAC42222.1
AJ312321 mRNA Translation: CAC42223.1
AJ312322 mRNA Translation: CAC42224.1
AF189712 mRNA Translation: AAF23373.1
AF189713 mRNA Translation: AAF23374.1
AF142408 mRNA Translation: AAG27919.1
AK022493 mRNA Translation: BAB14057.1 Sequence problems.
AK290368 mRNA Translation: BAF83057.1
AK056495 mRNA Translation: BAG51732.1
AK300270 mRNA Translation: BAG62031.1
AK303449 mRNA Translation: BAG64494.1
AK304143 mRNA Translation: BAG65036.1
AK299828 mRNA Translation: BAH13140.1
AK316473 mRNA Translation: BAH14844.1
BT007215 mRNA Translation: AAP35879.1
CH471099 Genomic DNA Translation: EAW89462.1
CH471099 Genomic DNA Translation: EAW89463.1
CH471099 Genomic DNA Translation: EAW89468.1
BC021192 mRNA Translation: AAH21192.1
BC054004 mRNA Translation: AAH54004.1
AB023208 mRNA Translation: BAA76835.2
AL080131 mRNA Translation: CAB45728.1
CCDSiCCDS45790.1 [Q9UHD8-1]
CCDS45791.1 [Q9UHD8-2]
CCDS45792.1 [Q9UHD8-5]
CCDS45793.1 [Q9UHD8-3]
CCDS45794.1 [Q9UHD8-8]
CCDS45795.1 [Q9UHD8-4]
CCDS74166.1 [Q9UHD8-9]
CCDS77122.1 [Q9UHD8-7]
PIRiT12519
RefSeqiNP_001106963.1, NM_001113491.1 [Q9UHD8-1]
NP_001106964.1, NM_001113492.1 [Q9UHD8-3]
NP_001106965.1, NM_001113493.1 [Q9UHD8-5]
NP_001106966.1, NM_001113494.1 [Q9UHD8-3]
NP_001106967.1, NM_001113495.1 [Q9UHD8-8]
NP_001106968.1, NM_001113496.1 [Q9UHD8-4]
NP_001280624.1, NM_001293695.1 [Q9UHD8-7]
NP_001280625.1, NM_001293696.1 [Q9UHD8-9]
NP_001280626.1, NM_001293697.1 [Q9UHD8-4]
NP_001280627.1, NM_001293698.1 [Q9UHD8-4]
NP_006631.2, NM_006640.4 [Q9UHD8-2]
XP_005257019.1, XM_005256962.1
XP_006721706.1, XM_006721643.2
XP_006721707.1, XM_006721644.1
XP_011522509.1, XM_011524207.1
XP_011522510.1, XM_011524208.2
XP_016879520.1, XM_017024031.1
XP_016879521.1, XM_017024032.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4YQFX-ray2.73A/B296-565[»]
5CYOX-ray2.04A/B295-568[»]
5CYPX-ray2.89A/B/C/D293-566[»]
SMRiQ9UHD8
ModBaseiSearch...

Protein-protein interaction databases

BioGridi116015, 82 interactors
CORUMiQ9UHD8
DIPiDIP-36697N
IntActiQ9UHD8, 40 interactors
MINTiQ9UHD8
STRINGi9606.ENSP00000391249

Chemistry databases

ChEMBLiCHEMBL4105891

PTM databases

CarbonylDBiQ9UHD8
iPTMnetiQ9UHD8
PhosphoSitePlusiQ9UHD8
SwissPalmiQ9UHD8

Polymorphism and mutation databases

BioMutaiSEPT9
DMDMi93141311

Proteomic databases

EPDiQ9UHD8
jPOSTiQ9UHD8
PaxDbiQ9UHD8
PeptideAtlasiQ9UHD8
PRIDEiQ9UHD8
ProteomicsDBi84325
84326 [Q9UHD8-2]
84327 [Q9UHD8-3]
84328 [Q9UHD8-4]
84329 [Q9UHD8-5]
84330 [Q9UHD8-7]
84331 [Q9UHD8-8]
84332 [Q9UHD8-9]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10801
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000329047; ENSP00000329161; ENSG00000184640 [Q9UHD8-2]
ENST00000423034; ENSP00000405877; ENSG00000184640 [Q9UHD8-5]
ENST00000427177; ENSP00000391249; ENSG00000184640 [Q9UHD8-1]
ENST00000427180; ENSP00000415624; ENSG00000184640 [Q9UHD8-8]
ENST00000427674; ENSP00000403194; ENSG00000184640 [Q9UHD8-3]
ENST00000431235; ENSP00000406987; ENSG00000184640 [Q9UHD8-3]
ENST00000449803; ENSP00000400181; ENSG00000184640 [Q9UHD8-3]
ENST00000541152; ENSP00000438089; ENSG00000184640 [Q9UHD8-4]
ENST00000585930; ENSP00000468120; ENSG00000184640 [Q9UHD8-9]
ENST00000588690; ENSP00000468668; ENSG00000184640 [Q9UHD8-3]
ENST00000590294; ENSP00000465464; ENSG00000184640 [Q9UHD8-2]
ENST00000591088; ENSP00000466247; ENSG00000184640 [Q9UHD8-4]
ENST00000591198; ENSP00000468406; ENSG00000184640 [Q9UHD8-7]
ENST00000592951; ENSP00000466648; ENSG00000184640 [Q9UHD8-4]
GeneIDi10801
KEGGihsa:10801
UCSCiuc002jts.5 human [Q9UHD8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10801
DisGeNETi10801

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SEPT9
GeneReviewsiSEPT9
HGNCiHGNC:7323 SEPTIN9
HPAiHPA042564
HPA050627
MalaCardsiSEPT9
MIMi162100 phenotype
604061 gene
neXtProtiNX_Q9UHD8
OpenTargetsiENSG00000184640
Orphaneti2901 Neuralgic amyotrophy
PharmGKBiPA31132

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1547 Eukaryota
COG5019 LUCA
GeneTreeiENSGT00940000157195
InParanoidiQ9UHD8
KOiK16938
OMAiKSHAGEF
OrthoDBi188544at2759
PhylomeDBiQ9UHD8
TreeFamiTF101078

Enzyme and pathway databases

SIGNORiQ9UHD8

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SEPT9 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
SEPT9

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10801

Protein Ontology

More...
PROi
PR:Q9UHD8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000184640 Expressed in 231 organ(s), highest expression level in parotid gland
ExpressionAtlasiQ9UHD8 baseline and differential
GenevisibleiQ9UHD8 HS

Family and domain databases

CDDicd01850 CDC_Septin, 1 hit
InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR027417 P-loop_NTPase
IPR030645 SEPT9
IPR016491 Septin
PANTHERiPTHR18884:SF47 PTHR18884:SF47, 1 hit
PfamiView protein in Pfam
PF00735 Septin, 1 hit
PIRSFiPIRSF006698 Septin, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSEPT9_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UHD8
Secondary accession number(s): A8K2V3
, B3KPM0, B4DTL9, B4E0N2, B4E274, B7Z654, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: April 18, 2006
Last modified: July 3, 2019
This is version 181 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again