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UniProtKB - Q9UHC6 (CNTP2_HUMAN)

Protein

Contactin-associated protein-like 2

Gene

CNTNAP2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.By similarity

GO - Molecular functioni

  • enzyme binding Source: BHF-UCL
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

Keywordsi

Biological processCell adhesion

Enzyme and pathway databases

SIGNORiQ9UHC6

Names & Taxonomyi

Protein namesi
Recommended name:
Contactin-associated protein-like 2
Alternative name(s):
Cell recognition molecule Caspr2
Gene namesi
Name:CNTNAP2
Synonyms:CASPR21 Publication, KIAA0868
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000174469.17
HGNCiHGNC:13830 CNTNAP2
MIMi604569 gene
neXtProtiNX_Q9UHC6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 1262ExtracellularSequence analysisAdd BLAST1235
Transmembranei1263 – 1283HelicalSequence analysisAdd BLAST21
Topological domaini1284 – 1331CytoplasmicSequence analysisAdd BLAST48

Keywords - Cellular componenti

Cell junction, Cell projection, Membrane

Pathology & Biotechi

Involvement in diseasei

Autism 15 (AUTS15)1 Publication
Disease susceptibility is associated with variations affecting the gene represented in this entry.
Disease descriptionA complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate mental retardation.
See also OMIM:612100
A chromosomal aberration involving CNTNAP2 is found in a patient with autism spectrum disorder. Paracentric inversion 46,XY,inv(7)(q11.22;q35). The inversion breakpoints disrupt the genes AUTS2 and CNTNAP2.
Pitt-Hopkins-like syndrome 1 (PTHSL1)2 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA syndrome characterized by severe mental retardation and variable additional symptoms, such as impaired speech development, seizures, autistic behavior, breathing anomalies and a broad mouth, resembling Pitt-Hopkins syndrome. In contrast to patients with Pitt-Hopkins syndrome, PTHSL1 patients present with normal or only mildly to moderately delayed motor milestones.
See also OMIM:610042

Keywords - Diseasei

Autism, Autism spectrum disorder, Epilepsy, Mental retardation

Organism-specific databases

DisGeNETi26047
MalaCardsiCNTNAP2
MIMi610042 phenotype
612100 phenotype
OpenTargetsiENSG00000174469
Orphaneti106 Autism
163681 Cortical dysplasia - focal epilepsy syndrome
221150 Pitt-Hopkins-like syndrome
PharmGKBiPA26692

Polymorphism and mutation databases

BioMutaiCNTNAP2
DMDMi17433089

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000001950628 – 1331Contactin-associated protein-like 2Add BLAST1304

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi35 ↔ 181By similarity
Glycosylationi289N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi336 ↔ 368By similarity
Glycosylationi346N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi363N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi379N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi436N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi506N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi507N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi520 ↔ 552By similarity
Glycosylationi546N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi558 ↔ 569By similarity
Disulfide bondi563 ↔ 578By similarity
Disulfide bondi580 ↔ 590By similarity
Glycosylationi630N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi735N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi936 ↔ 963By similarity
Disulfide bondi967 ↔ 980By similarity
Disulfide bondi974 ↔ 989By similarity
Disulfide bondi991 ↔ 1001By similarity
Glycosylationi1116N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1178 ↔ 1214By similarity
Glycosylationi1198N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei1303PhosphoserineBy similarity1
Modified residuei1306PhosphoserineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

EPDiQ9UHC6
PaxDbiQ9UHC6
PeptideAtlasiQ9UHC6
PRIDEiQ9UHC6
ProteomicsDBi84311
84312 [Q9UHC6-2]

PTM databases

iPTMnetiQ9UHC6
PhosphoSitePlusiQ9UHC6
SwissPalmiQ9UHC6

Expressioni

Tissue specificityi

Predominantly expressed in nervous system.1 Publication

Gene expression databases

BgeeiENSG00000174469 Expressed in 163 organ(s), highest expression level in forebrain
CleanExiHS_CNTNAP2
ExpressionAtlasiQ9UHC6 baseline and differential
GenevisibleiQ9UHC6 HS

Organism-specific databases

HPAiHPA002739

Interactioni

Subunit structurei

Interacts (via C-terminus) with KCNA2.1 Publication

Binary interactionsi

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridi117510, 8 interactors
IntActiQ9UHC6, 12 interactors
MINTiQ9UHC6
STRINGi9606.ENSP00000354778

Structurei

3D structure databases

ProteinModelPortaliQ9UHC6
SMRiQ9UHC6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 181F5/8 type CPROSITE-ProRule annotationAdd BLAST147
Domaini216 – 368Laminin G-like 1PROSITE-ProRule annotationAdd BLAST153
Domaini401 – 552Laminin G-like 2PROSITE-ProRule annotationAdd BLAST152
Domaini554 – 591EGF-like 1PROSITE-ProRule annotationAdd BLAST38
Domaini592 – 798Fibrinogen C-terminalPROSITE-ProRule annotationAdd BLAST207
Domaini799 – 963Laminin G-like 3PROSITE-ProRule annotationAdd BLAST165
Domaini963 – 1002EGF-like 2PROSITE-ProRule annotationAdd BLAST40
Domaini1055 – 1214Laminin G-like 4PROSITE-ProRule annotationAdd BLAST160

Sequence similaritiesi

Belongs to the neurexin family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3516 Eukaryota
ENOG410XPHG LUCA
GeneTreeiENSGT00760000118991
HOGENOMiHOG000230964
HOVERGENiHBG057718
InParanoidiQ9UHC6
KOiK07380
OMAiQKCDEPL
OrthoDBiEOG091G00LF
PhylomeDBiQ9UHC6
TreeFamiTF321823

Family and domain databases

CDDicd00057 FA58C, 1 hit
Gene3Di2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR029831 Caspr2
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR000421 FA58C
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR008979 Galactose-bd-like_sf
IPR001791 Laminin_G
IPR003585 Neurexin-like
PANTHERiPTHR43925:SF3 PTHR43925:SF3, 1 hit
PfamiView protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF02210 Laminin_G_2, 4 hits
SMARTiView protein in SMART
SM00294 4.1m, 1 hit
SM00181 EGF, 2 hits
SM00231 FA58C, 1 hit
SM00282 LamG, 4 hits
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 4 hits
SSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 2 hits
PS01285 FA58C_1, 1 hit
PS01286 FA58C_2, 1 hit
PS50022 FA58C_3, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50025 LAM_G_DOMAIN, 4 hits

Sequences (2+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UHC6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQAAPRAGCG AALLLWIVSS CLCRAWTAPS TSQKCDEPLV SGLPHVAFSS 
        60         70         80         90        100
SSSISGSYSP GYAKINKRGG AGGWSPSDSD HYQWLQVDFG NRKQISAIAT 
       110        120        130        140        150
QGRYSSSDWV TQYRMLYSDT GRNWKPYHQD GNIWAFPGNI NSDGVVRHEL 
       160        170        180        190        200
QHPIIARYVR IVPLDWNGEG RIGLRIEVYG CSYWADVINF DGHVVLPYRF 
       210        220        230        240        250
RNKKMKTLKD VIALNFKTSE SEGVILHGEG QQGDYITLEL KKAKLVLSLN 
       260        270        280        290        300
LGSNQLGPIY GHTSVMTGSL LDDHHWHSVV IERQGRSINL TLDRSMQHFR 
       310        320        330        340        350
TNGEFDYLDL DYEITFGGIP FSGKPSSSSR KNFKGCMESI NYNGVNITDL 
       360        370        380        390        400
ARRKKLEPSN VGNLSFSCVE PYTVPVFFNA TSYLEVPGRL NQDLFSVSFQ 
       410        420        430        440        450
FRTWNPNGLL VFSHFADNLG NVEIDLTESK VGVHINITQT KMSQIDISSG 
       460        470        480        490        500
SGLNDGQWHE VRFLAKENFA ILTIDGDEAS AVRTNSPLQV KTGEKYFFGG 
       510        520        530        540        550
FLNQMNNSSH SVLQPSFQGC MQLIQVDDQL VNLYEVAQRK PGSFANVSID 
       560        570        580        590        600
MCAIIDRCVP NHCEHGGKCS QTWDSFKCTC DETGYSGATC HNSIYEPSCE 
       610        620        630        640        650
AYKHLGQTSN YYWIDPDGSG PLGPLKVYCN MTEDKVWTIV SHDLQMQTPV 
       660        670        680        690        700
VGYNPEKYSV TQLVYSASMD QISAITDSAE YCEQYVSYFC KMSRLLNTPD 
       710        720        730        740        750
GSPYTWWVGK ANEKHYYWGG SGPGIQKCAC GIERNCTDPK YYCNCDADYK 
       760        770        780        790        800
QWRKDAGFLS YKDHLPVSQV VVGDTDRQGS EAKLSVGPLR CQGDRNYWNA 
       810        820        830        840        850
ASFPNPSSYL HFSTFQGETS ADISFYFKTL TPWGVFLENM GKEDFIKLEL 
       860        870        880        890        900
KSATEVSFSF DVGNGPVEIV VRSPTPLNDD QWHRVTAERN VKQASLQVDR 
       910        920        930        940        950
LPQQIRKAPT EGHTRLELYS QLFVGGAGGQ QGFLGCIRSL RMNGVTLDLE 
       960        970        980        990       1000
ERAKVTSGFI SGCSGHCTSY GTNCENGGKC LERYHGYSCD CSNTAYDGTF 
      1010       1020       1030       1040       1050
CNKDVGAFFE EGMWLRYNFQ APATNARDSS SRVDNAPDQQ NSHPDLAQEE 
      1060       1070       1080       1090       1100
IRFSFSTTKA PCILLYISSF TTDFLAVLVK PTGSLQIRYN LGGTREPYNI 
      1110       1120       1130       1140       1150
DVDHRNMANG QPHSVNITRH EKTIFLKLDH YPSVSYHLPS SSDTLFNSPK 
      1160       1170       1180       1190       1200
SLFLGKVIET GKIDQEIHKY NTPGFTGCLS RVQFNQIAPL KAALRQTNAS 
      1210       1220       1230       1240       1250
AHVHIQGELV ESNCGASPLT LSPMSSATDP WHLDHLDSAS ADFPYNPGQG 
      1260       1270       1280       1290       1300
QAIRNGVNRN SAIIGGVIAV VIFTILCTLV FLIRYMFRHK GTYHTNEAKG 
      1310       1320       1330 
AESAESADAA IMNNDPNFTE TIDESKKEWL I
Length:1,331
Mass (Da):148,167
Last modified:May 1, 2000 - v1
Checksum:iCFB2CB55BEFB99C2
GO
Isoform 2 (identifier: Q9UHC6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1223: Missing.

Note: No experimental confirmation available.
Show »
Length:108
Mass (Da):11,899
Checksum:iF0EB322C735B773E
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B7Z1Y6B7Z1Y6_HUMAN
cDNA FLJ53861, highly similar to Co...
CNTNAP2
390Annotation score:
A0A0J9YWG3A0A0J9YWG3_HUMAN
Contactin-associated protein-like 2
CNTNAP2
328Annotation score:
A0A0J9YYA0A0A0J9YYA0_HUMAN
Contactin-associated protein-like 2
CNTNAP2
328Annotation score:
A0A0D9SES4A0A0D9SES4_HUMAN
Contactin-associated protein-like 2
CNTNAP2
119Annotation score:

Sequence cautioni

The sequence BAA74891 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_046227114R → Q1 PublicationCorresponds to variant dbSNP:rs189731792EnsemblClinVar.1
Natural variantiVAR_046228218T → M1 PublicationCorresponds to variant dbSNP:rs771028883EnsemblClinVar.1
Natural variantiVAR_046229226L → M1 PublicationCorresponds to variant dbSNP:rs372345438EnsemblClinVar.1
Natural variantiVAR_046230283R → C1 PublicationCorresponds to variant dbSNP:rs794727802EnsemblClinVar.1
Natural variantiVAR_046231382S → N1 PublicationCorresponds to variant dbSNP:rs371839994EnsemblClinVar.1
Natural variantiVAR_046232407N → S1 PublicationCorresponds to variant dbSNP:rs143877693EnsemblClinVar.1
Natural variantiVAR_046233418N → D1 PublicationCorresponds to variant dbSNP:rs772179690Ensembl.1
Natural variantiVAR_046234680E → K1 PublicationCorresponds to variant dbSNP:rs368905425Ensembl.1
Natural variantiVAR_046235699P → Q1 PublicationCorresponds to variant dbSNP:rs764412489Ensembl.1
Natural variantiVAR_046236716Y → C1 PublicationCorresponds to variant dbSNP:rs760930032EnsemblClinVar.1
Natural variantiVAR_046237731G → S1 PublicationCorresponds to variant dbSNP:rs369867547EnsemblClinVar.1
Natural variantiVAR_046238779G → D1 PublicationCorresponds to variant dbSNP:rs200413148Ensembl.1
Natural variantiVAR_046239869I → T Rare polymorphism; may be a risk factor for autism. 1 PublicationCorresponds to variant dbSNP:rs121908445EnsemblClinVar.1
Natural variantiVAR_046240906R → H1 PublicationCorresponds to variant dbSNP:rs759801195EnsemblClinVar.1
Natural variantiVAR_0462411038D → N1 PublicationCorresponds to variant dbSNP:rs144003410EnsemblClinVar.1
Natural variantiVAR_0462421102V → A1 PublicationCorresponds to variant dbSNP:rs111599875EnsemblClinVar.1
Natural variantiVAR_0462431114S → G1 PublicationCorresponds to variant dbSNP:rs983036503Ensembl.1
Natural variantiVAR_0462441119R → H1 PublicationCorresponds to variant dbSNP:rs774709566Ensembl.1
Natural variantiVAR_0462451129D → H1 PublicationCorresponds to variant dbSNP:rs781236853Ensembl.1
Natural variantiVAR_0462461227A → T1 PublicationCorresponds to variant dbSNP:rs761684414Ensembl.1
Natural variantiVAR_0462471253I → T1 PublicationCorresponds to variant dbSNP:rs767821521EnsemblClinVar.1
Natural variantiVAR_0462481278T → I1 PublicationCorresponds to variant dbSNP:rs760047247Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0149761 – 1223Missing in isoform 2. 1 PublicationAdd BLAST1223

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF193613 mRNA Translation: AAF25199.1
AF319045 mRNA Translation: AAK34932.1
AF318292 Genomic DNA Translation: AAK49902.1
AF318298 Genomic DNA Translation: AAK49903.1
AB020675 mRNA Translation: BAA74891.1 Different initiation.
CR933671 mRNA Translation: CAI45967.1
CH471146 Genomic DNA Translation: EAW80084.1
BC093780 mRNA Translation: AAH93780.1
BC113373 mRNA Translation: AAI13374.1
CCDSiCCDS5889.1 [Q9UHC6-1]
RefSeqiNP_054860.1, NM_014141.5 [Q9UHC6-1]
UniGeneiHs.655684

Genome annotation databases

EnsembliENST00000361727; ENSP00000354778; ENSG00000174469 [Q9UHC6-1]
ENST00000463592; ENSP00000486292; ENSG00000174469 [Q9UHC6-2]
ENST00000613345; ENSP00000481057; ENSG00000278728 [Q9UHC6-2]
GeneIDi26047
KEGGihsa:26047
UCSCiuc003weu.3 human [Q9UHC6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement, Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF193613 mRNA Translation: AAF25199.1
AF319045 mRNA Translation: AAK34932.1
AF318292 Genomic DNA Translation: AAK49902.1
AF318298 Genomic DNA Translation: AAK49903.1
AB020675 mRNA Translation: BAA74891.1 Different initiation.
CR933671 mRNA Translation: CAI45967.1
CH471146 Genomic DNA Translation: EAW80084.1
BC093780 mRNA Translation: AAH93780.1
BC113373 mRNA Translation: AAI13374.1
CCDSiCCDS5889.1 [Q9UHC6-1]
RefSeqiNP_054860.1, NM_014141.5 [Q9UHC6-1]
UniGeneiHs.655684

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5Y4MX-ray1.31A35-181[»]
ProteinModelPortaliQ9UHC6
SMRiQ9UHC6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117510, 8 interactors
IntActiQ9UHC6, 12 interactors
MINTiQ9UHC6
STRINGi9606.ENSP00000354778

PTM databases

iPTMnetiQ9UHC6
PhosphoSitePlusiQ9UHC6
SwissPalmiQ9UHC6

Polymorphism and mutation databases

BioMutaiCNTNAP2
DMDMi17433089

Proteomic databases

EPDiQ9UHC6
PaxDbiQ9UHC6
PeptideAtlasiQ9UHC6
PRIDEiQ9UHC6
ProteomicsDBi84311
84312 [Q9UHC6-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361727; ENSP00000354778; ENSG00000174469 [Q9UHC6-1]
ENST00000463592; ENSP00000486292; ENSG00000174469 [Q9UHC6-2]
ENST00000613345; ENSP00000481057; ENSG00000278728 [Q9UHC6-2]
GeneIDi26047
KEGGihsa:26047
UCSCiuc003weu.3 human [Q9UHC6-1]

Organism-specific databases

CTDi26047
DisGeNETi26047
EuPathDBiHostDB:ENSG00000174469.17
GeneCardsiCNTNAP2
HGNCiHGNC:13830 CNTNAP2
HPAiHPA002739
MalaCardsiCNTNAP2
MIMi604569 gene
610042 phenotype
612100 phenotype
neXtProtiNX_Q9UHC6
OpenTargetsiENSG00000174469
Orphaneti106 Autism
163681 Cortical dysplasia - focal epilepsy syndrome
221150 Pitt-Hopkins-like syndrome
PharmGKBiPA26692
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3516 Eukaryota
ENOG410XPHG LUCA
GeneTreeiENSGT00760000118991
HOGENOMiHOG000230964
HOVERGENiHBG057718
InParanoidiQ9UHC6
KOiK07380
OMAiQKCDEPL
OrthoDBiEOG091G00LF
PhylomeDBiQ9UHC6
TreeFamiTF321823

Enzyme and pathway databases

SIGNORiQ9UHC6

Miscellaneous databases

ChiTaRSiCNTNAP2 human
GeneWikiiCNTNAP2
GenomeRNAii26047
PROiPR:Q9UHC6
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000174469 Expressed in 163 organ(s), highest expression level in forebrain
CleanExiHS_CNTNAP2
ExpressionAtlasiQ9UHC6 baseline and differential
GenevisibleiQ9UHC6 HS

Family and domain databases

CDDicd00057 FA58C, 1 hit
Gene3Di2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR029831 Caspr2
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR000421 FA58C
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR008979 Galactose-bd-like_sf
IPR001791 Laminin_G
IPR003585 Neurexin-like
PANTHERiPTHR43925:SF3 PTHR43925:SF3, 1 hit
PfamiView protein in Pfam
PF00754 F5_F8_type_C, 1 hit
PF02210 Laminin_G_2, 4 hits
SMARTiView protein in SMART
SM00294 4.1m, 1 hit
SM00181 EGF, 2 hits
SM00231 FA58C, 1 hit
SM00282 LamG, 4 hits
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 4 hits
SSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 2 hits
PS01285 FA58C_1, 1 hit
PS01286 FA58C_2, 1 hit
PS50022 FA58C_3, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50025 LAM_G_DOMAIN, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiCNTP2_HUMAN
AccessioniPrimary (citable) accession number: Q9UHC6
Secondary accession number(s): D3DWG2
, Q14DG2, Q52LV1, Q5H9Q7, Q9UQ12
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 5, 2001
Last sequence update: May 1, 2000
Last modified: October 10, 2018
This is version 182 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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