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UniProtKB - Q9UHA2 (S18L2_HUMAN)
Protein
SS18-like protein 2
Gene
SS18L2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- transcription coactivator activity Source: InterPro
GO - Biological processi
- positive regulation of dendrite morphogenesis Source: GO_Central
- positive regulation of transcription by RNA polymerase II Source: GO_Central
Enzyme and pathway databases
PathwayCommonsi | Q9UHA2 |
SignaLinki | Q9UHA2 |
Names & Taxonomyi
Protein namesi | Recommended name: SS18-like protein 2Alternative name(s): SYT homolog 2 |
Gene namesi | Name:SS18L2 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:15593, SS18L2 |
MIMi | 606473, gene |
neXtProti | NX_Q9UHA2 |
VEuPathDBi | HostDB:ENSG00000008324 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 51188 |
OpenTargetsi | ENSG00000008324 |
PharmGKBi | PA37990 |
Miscellaneous databases
Pharosi | Q9UHA2, Tdark |
Genetic variation databases
BioMutai | SS18L2 |
DMDMi | 24418678 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000181826 | 1 – 77 | SS18-like protein 2Add BLAST | 77 |
Proteomic databases
EPDi | Q9UHA2 |
jPOSTi | Q9UHA2 |
MassIVEi | Q9UHA2 |
MaxQBi | Q9UHA2 |
PaxDbi | Q9UHA2 |
PeptideAtlasi | Q9UHA2 |
PRIDEi | Q9UHA2 |
ProteomicsDBi | 84290 |
PTM databases
iPTMneti | Q9UHA2 |
PhosphoSitePlusi | Q9UHA2 |
Expressioni
Gene expression databases
Bgeei | ENSG00000008324, Expressed in prostate gland and 239 other tissues |
ExpressionAtlasi | Q9UHA2, baseline and differential |
Genevisiblei | Q9UHA2, HS |
Organism-specific databases
HPAi | ENSG00000008324, Low tissue specificity |
Interactioni
Binary interactionsi
Q9UHA2
Protein-protein interaction databases
BioGRIDi | 119363, 72 interactors |
IntActi | Q9UHA2, 45 interactors |
STRINGi | 9606.ENSP00000401115 |
Miscellaneous databases
RNActi | Q9UHA2, protein |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 50 – 53 | SH2-bindingSequence analysis | 4 |
Sequence similaritiesi
Belongs to the SS18 family.Curated
Phylogenomic databases
eggNOGi | KOG3227, Eukaryota |
GeneTreei | ENSGT00940000160407 |
HOGENOMi | CLU_164146_1_0_1 |
InParanoidi | Q9UHA2 |
OMAi | GRAHECV |
OrthoDBi | 1442230at2759 |
PhylomeDBi | Q9UHA2 |
Family and domain databases
InterProi | View protein in InterPro IPR044779, SS18 IPR007726, SS18_N |
PANTHERi | PTHR23107, PTHR23107, 1 hit |
Pfami | View protein in Pfam PF05030, SSXT, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9UHA2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSVAFVPDWL RGKAEVNQET IQRLLEENDQ LIRCIVEYQN KGRGNECVQY
60 70
QHVLHRNLIY LATIADASPT STSKAME
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF201950 mRNA Translation: AAF17242.1 AK312225 mRNA Translation: BAG35158.1 CH471055 Genomic DNA Translation: EAW64657.1 BC017804 mRNA Translation: AAH17804.1 |
CCDSi | CCDS2701.1 |
RefSeqi | NP_057389.1, NM_016305.3 XP_016862037.1, XM_017006548.1 XP_016862038.1, XM_017006549.1 |
Genome annotation databases
Ensembli | ENST00000011691.6; ENSP00000011691.4; ENSG00000008324.12 ENST00000447630.5; ENSP00000401115.1; ENSG00000008324.12 |
GeneIDi | 51188 |
KEGGi | hsa:51188 |
MANE-Selecti | ENST00000011691.6; ENSP00000011691.4; NM_001370300.1; NP_001357229.1 |
UCSCi | uc003clk.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF201950 mRNA Translation: AAF17242.1 AK312225 mRNA Translation: BAG35158.1 CH471055 Genomic DNA Translation: EAW64657.1 BC017804 mRNA Translation: AAH17804.1 |
CCDSi | CCDS2701.1 |
RefSeqi | NP_057389.1, NM_016305.3 XP_016862037.1, XM_017006548.1 XP_016862038.1, XM_017006549.1 |
3D structure databases
AlphaFoldDBi | Q9UHA2 |
SMRi | Q9UHA2 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 119363, 72 interactors |
IntActi | Q9UHA2, 45 interactors |
STRINGi | 9606.ENSP00000401115 |
PTM databases
iPTMneti | Q9UHA2 |
PhosphoSitePlusi | Q9UHA2 |
Genetic variation databases
BioMutai | SS18L2 |
DMDMi | 24418678 |
Proteomic databases
EPDi | Q9UHA2 |
jPOSTi | Q9UHA2 |
MassIVEi | Q9UHA2 |
MaxQBi | Q9UHA2 |
PaxDbi | Q9UHA2 |
PeptideAtlasi | Q9UHA2 |
PRIDEi | Q9UHA2 |
ProteomicsDBi | 84290 |
Protocols and materials databases
Antibodypediai | 29253, 25 antibodies from 14 providers |
DNASUi | 51188 |
Genome annotation databases
Ensembli | ENST00000011691.6; ENSP00000011691.4; ENSG00000008324.12 ENST00000447630.5; ENSP00000401115.1; ENSG00000008324.12 |
GeneIDi | 51188 |
KEGGi | hsa:51188 |
MANE-Selecti | ENST00000011691.6; ENSP00000011691.4; NM_001370300.1; NP_001357229.1 |
UCSCi | uc003clk.1, human |
Organism-specific databases
CTDi | 51188 |
DisGeNETi | 51188 |
GeneCardsi | SS18L2 |
HGNCi | HGNC:15593, SS18L2 |
HPAi | ENSG00000008324, Low tissue specificity |
MIMi | 606473, gene |
neXtProti | NX_Q9UHA2 |
OpenTargetsi | ENSG00000008324 |
PharmGKBi | PA37990 |
VEuPathDBi | HostDB:ENSG00000008324 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3227, Eukaryota |
GeneTreei | ENSGT00940000160407 |
HOGENOMi | CLU_164146_1_0_1 |
InParanoidi | Q9UHA2 |
OMAi | GRAHECV |
OrthoDBi | 1442230at2759 |
PhylomeDBi | Q9UHA2 |
Enzyme and pathway databases
PathwayCommonsi | Q9UHA2 |
SignaLinki | Q9UHA2 |
Miscellaneous databases
BioGRID-ORCSi | 51188, 796 hits in 1079 CRISPR screens |
ChiTaRSi | SS18L2, human |
GenomeRNAii | 51188 |
Pharosi | Q9UHA2, Tdark |
PROi | PR:Q9UHA2 |
RNActi | Q9UHA2, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000008324, Expressed in prostate gland and 239 other tissues |
ExpressionAtlasi | Q9UHA2, baseline and differential |
Genevisiblei | Q9UHA2, HS |
Family and domain databases
InterProi | View protein in InterPro IPR044779, SS18 IPR007726, SS18_N |
PANTHERi | PTHR23107, PTHR23107, 1 hit |
Pfami | View protein in Pfam PF05030, SSXT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S18L2_HUMAN | |
Accessioni | Q9UHA2Primary (citable) accession number: Q9UHA2 Secondary accession number(s): B2R5L1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 25, 2002 |
Last sequence update: | May 1, 2000 | |
Last modified: | May 25, 2022 | |
This is version 129 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families