SS18L2

Functionⁱ

GO - Molecular functionⁱ

transcription coactivator activity Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: SS18-like protein 2 Alternative name(s): SYT homolog 2
Gene namesⁱ	Name:SS18L2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 3

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000008324.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:15593 SS18L2
MIMⁱ	606473 gene
neXtProtⁱ	NX_Q9UHA2

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000008324
PharmGKBⁱ	PA37990

Polymorphism and mutation databases

BioMutaⁱ	SS18L2
DMDMⁱ	24418678

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000181826	1 – 77	SS18-like protein 2Add BLAST		77

Proteomic databases

EPDⁱ	Q9UHA2
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9UHA2
PaxDbⁱ	Q9UHA2
PeptideAtlas More...PeptideAtlasⁱ	Q9UHA2
PRIDEⁱ	Q9UHA2
ProteomicsDBⁱ	84290

PTM databases

iPTMnetⁱ	Q9UHA2
PhosphoSitePlusⁱ	Q9UHA2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000008324 Expressed in 227 organ(s), highest expression level in prostate gland
CleanExⁱ	HS_SS18L2
ExpressionAtlasⁱ	Q9UHA2 baseline and differential
Genevisibleⁱ	Q9UHA2 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA047377

HPAⁱ

HPA047377

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	119363, 22 interactors
IntActⁱ	Q9UHA2, 22 interactors
STRINGⁱ	9606.ENSP00000011691

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9UHA2
SMRⁱ	Q9UHA2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	50 – 53	SH2-bindingSequence analysis		4

Sequence similaritiesⁱ

Belongs to the SS18 family.Curated

Phylogenomic databases

eggNOGⁱ	KOG3227 Eukaryota ENOG41128HA LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00500000044808
HOGENOMⁱ	HOG000265025
HOVERGENⁱ	HBG054385
InParanoidⁱ	Q9UHA2
OMAⁱ	MQKGRAV
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0O10
PhylomeDBⁱ	Q9UHA2

Family and domain databases

InterProⁱ	View protein in InterPro IPR007726 SS18_fam
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05030 SSXT, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9UHA2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSVAFVPDWL RGKAEVNQET IQRLLEENDQ LIRCIVEYQN KGRGNECVQY 
        60         70 
QHVLHRNLIY LATIADASPT STSKAME

Length:77

Mass (Da):8,835

Last modified:May 1, 2000 - v1

Checksum:ⁱ2204523E5B412BBF

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF201950 mRNA Translation: AAF17242.1 AK312225 mRNA Translation: BAG35158.1 CH471055 Genomic DNA Translation: EAW64657.1 BC017804 mRNA Translation: AAH17804.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS2701.1
NCBI Reference Sequences More...RefSeqⁱ	NP_057389.1, NM_016305.3 XP_016862037.1, XM_017006548.1 XP_016862038.1, XM_017006549.1
UniGeneⁱ	Hs.534454

Genome annotation databases

Ensemblⁱ	ENST00000011691; ENSP00000011691; ENSG00000008324 ENST00000447630; ENSP00000401115; ENSG00000008324
GeneIDⁱ	51188
KEGGⁱ	hsa:51188
UCSC genome browser More...UCSCⁱ	uc003clk.1 human

Protein	Similar proteins		Species	Score	Length	Source
Q9UHA2	Synovial sarcoma translocation gene on chromosome 18-like 2, isoform CRA_a		HUMAN		77	UniRef100_Q9UHA2
SS18 like 2		MACMU		77
SS18 like 2		PANTR		77
SS18 like 2		MACFA		77
SS18 like 2		PONAB		77
+10

Protein	Similar proteins		Species	Score	Length	Source
Q9UHA2	Synovial sarcoma translocation gene on chromosome 18-like 2, isoform CRA_a		HUMAN		77	UniRef90_Q9UHA2
SS18 like 2		MACMU		77
SS18 like 2		PANTR		77
SS18 like 2		MACFA		77
SS18 like 2		PONAB		77
+10

Protein	Similar proteins		Species	Score	Length	Source
Q9UHA2	Synovial sarcoma translocation gene on chromosome 18-like 2, isoform CRA_a		HUMAN		77	UniRef50_Q9UHA2
SS18 like 2		MACMU		77
SS18 like 2		PANTR		77
SS18 like 2		MACFA		77
SS18 like 2		PONAB		77
+71

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF201950 mRNA Translation: AAF17242.1 AK312225 mRNA Translation: BAG35158.1 CH471055 Genomic DNA Translation: EAW64657.1 BC017804 mRNA Translation: AAH17804.1
CCDSⁱ	CCDS2701.1
RefSeqⁱ	NP_057389.1, NM_016305.3 XP_016862037.1, XM_017006548.1 XP_016862038.1, XM_017006549.1
UniGeneⁱ	Hs.534454

3D structure databases

ProteinModelPortalⁱ	Q9UHA2
SMRⁱ	Q9UHA2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	119363, 22 interactors
IntActⁱ	Q9UHA2, 22 interactors
STRINGⁱ	9606.ENSP00000011691

PTM databases

iPTMnetⁱ	Q9UHA2
PhosphoSitePlusⁱ	Q9UHA2

Polymorphism and mutation databases

BioMutaⁱ	SS18L2
DMDMⁱ	24418678

Proteomic databases

EPDⁱ	Q9UHA2
MaxQBⁱ	Q9UHA2
PaxDbⁱ	Q9UHA2
PeptideAtlasⁱ	Q9UHA2
PRIDEⁱ	Q9UHA2
ProteomicsDBⁱ	84290

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	51188
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000011691; ENSP00000011691; ENSG00000008324 ENST00000447630; ENSP00000401115; ENSG00000008324
GeneIDⁱ	51188
KEGGⁱ	hsa:51188
UCSCⁱ	uc003clk.1 human

Organism-specific databases

CTDⁱ	51188
EuPathDBⁱ	HostDB:ENSG00000008324.10
GeneCardsⁱ	SS18L2
HGNCⁱ	HGNC:15593 SS18L2
HPAⁱ	HPA047377
MIMⁱ	606473 gene
neXtProtⁱ	NX_Q9UHA2
OpenTargetsⁱ	ENSG00000008324
PharmGKBⁱ	PA37990
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3227 Eukaryota ENOG41128HA LUCA
GeneTreeⁱ	ENSGT00500000044808
HOGENOMⁱ	HOG000265025
HOVERGENⁱ	HBG054385
InParanoidⁱ	Q9UHA2
OMAⁱ	MQKGRAV
OrthoDBⁱ	EOG091G0O10
PhylomeDBⁱ	Q9UHA2

Miscellaneous databases

GenomeRNAiⁱ	51188
Protein Ontology More...PROⁱ	PR:Q9UHA2
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000008324 Expressed in 227 organ(s), highest expression level in prostate gland
CleanExⁱ	HS_SS18L2
ExpressionAtlasⁱ	Q9UHA2 baseline and differential
Genevisibleⁱ	Q9UHA2 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR007726 SS18_fam
Pfamⁱ	View protein in Pfam PF05030 SSXT, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	S18L2_HUMAN
Accessionⁱ	Q9UHA2Primary (citable) accession number: Q9UHA2 Secondary accession number(s): B2R5L1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 25, 2002
	Last sequence update:	May 1, 2000
	Last modified:	September 12, 2018
	This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

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Annotation systems

Supporting data

UniProtKB - Q9UHA2 (S18L2_HUMAN)

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SS18-like protein 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ