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Protein

F-box only protein 40

Gene

FBXO40

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis.By similarity

Miscellaneous

The expression decreases in the dystrophic muscle of Limb-girdle muscular dystrophy (LGMD) patient.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri53 – 112TRAF-typePROSITE-ProRule annotationAdd BLAST60

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • muscle cell differentiation Source: UniProtKB
  • post-translational protein modification Source: Reactome
  • protein polyubiquitination Source: Reactome

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-8951664 Neddylation
R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
F-box only protein 40
Alternative name(s):
Muscle disease-related protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FBXO40
Synonyms:FBX40, KIAA1195
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000163833.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29816 FBXO40

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609107 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UH90

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
51725

Open Targets

More...
OpenTargetsi
ENSG00000163833

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134971542

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FBXO40

Domain mapping of disease mutations (DMDM)

More...
DMDMi
124012094

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001199381 – 709F-box only protein 40Add BLAST709

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UH90

PeptideAtlas

More...
PeptideAtlasi
Q9UH90

PRoteomics IDEntifications database

More...
PRIDEi
Q9UH90

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84285

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UH90

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UH90

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed only in heart and skeletal muscle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000163833 Expressed in 86 organ(s), highest expression level in deltoid

CleanEx database of gene expression profiles

More...
CleanExi
HS_FBXO40

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UH90 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Directly interacts with SKP1 and CUL1.By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119698, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UH90, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000337510

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UH90

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UH90

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini570 – 624F-boxPROSITE-ProRule annotationAdd BLAST55

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri53 – 112TRAF-typePROSITE-ProRule annotationAdd BLAST60

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEIY Eukaryota
ENOG410ZQ6P LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00410000025582

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000059618

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG100177

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UH90

KEGG Orthology (KO)

More...
KOi
K10315

Identification of Orthologs from Complete Genome Data

More...
OMAi
HELLCPL

Database of Orthologous Groups

More...
OrthoDBi
EOG091G06SE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UH90

TreeFam database of animal gene trees

More...
TreeFami
TF343227

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR031890 Fbxo30/Fbxo40
IPR008974 TRAF-like
IPR013083 Znf_RING/FYVE/PHD
IPR001293 Znf_TRAF

The PANTHER Classification System

More...
PANTHERi
PTHR15933 PTHR15933, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15966 F-box_4, 1 hit
PF15965 zf-TRAF_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49599 SSF49599, 1 hit
SSF81383 SSF81383, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50181 FBOX, 1 hit
PS50145 ZF_TRAF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UH90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKARRSPPG HHRHCEGCFN RHCHIPVEPN TSCLVISCHL LCGATFHMCK
60 70 80 90 100
EAEHQLLCPL EQVPCLNSEY GCPLSMSRHK LAKHLQVCPA SVVCCSMEWN
110 120 130 140 150
RWPNVDSETT LHENIMKETP SEECLDTALA LQDQKVLFRS LKMVELFPET
160 170 180 190 200
REATEEEPTM NGETSVEEMG GAVGGVDIGL VPHGLSATNG EMAELSQEER
210 220 230 240 250
EVLAKTKEGM DLVKFGQWEN IFSKEHAASA LTNSSASCES KNKNDSEKEQ
260 270 280 290 300
ISSGHNMVEG EGAPKKKEPQ ENQKQQDVRT AMETTGLAPW QDGVLERLKT
310 320 330 340 350
AVDAKDYNMY LVHNGRMLIH FGQMPACTPK ERDFVYGKLE AQEVKTVYTF
360 370 380 390 400
KVPVSYCGKR ARLGDAMLSC KPSEHKAVDT SDLGITVEDL PKSDLIKTTL
410 420 430 440 450
QCALERELKG HVISESRSID GLFMDFATQT YNFEPEQFSS GTVLADLTAA
460 470 480 490 500
TPGGLHVELH SECVTRRHNK SSSAFTFTCN KFFRRDEFPL HFKNVHTDIQ
510 520 530 540 550
SCLNGWFQHR CPLAYLGCTF VQNHFRPPGQ KAKVIYSQEL KTFAIKPEVA
560 570 580 590 600
PELSEGRKNN HLLGHGGKSQ NSLTSLPLEI LKYIAGFLDS VSLAQLSQVS
610 620 630 640 650
VLMRNICATL LQERGMVLLQ WKKKRYSHGG TSWRVHREIW QFSSLFSKIK
660 670 680 690 700
SWEFNEVTSM SEHLKSCPFN IVEHKTDPIL LTSMCQPREQ ARESLVSTFR

IRPRGRYVS
Length:709
Mass (Da):79,782
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4B69F51EA78D78E3
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA86509 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti45T → A in AAF17085 (Ref. 1) Curated1
Sequence conflicti146L → P in AAF17085 (Ref. 1) Curated1
Sequence conflicti388E → G in AAF17085 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03000587V → A. Corresponds to variant dbSNP:rs4676684Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF204674 mRNA Translation: AAF17085.1
AB033021 mRNA Translation: BAA86509.1 Different initiation.
AK314400 mRNA Translation: BAG37024.1
AC063920 Genomic DNA No translation available.
CH471052 Genomic DNA Translation: EAW79508.1
BC109275 mRNA Translation: AAI09276.1
BC109276 mRNA Translation: AAI09277.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33835.1

NCBI Reference Sequences

More...
RefSeqi
NP_057382.2, NM_016298.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.272564

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000338040; ENSP00000337510; ENSG00000163833

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51725

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51725

UCSC genome browser

More...
UCSCi
uc003eeg.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF204674 mRNA Translation: AAF17085.1
AB033021 mRNA Translation: BAA86509.1 Different initiation.
AK314400 mRNA Translation: BAG37024.1
AC063920 Genomic DNA No translation available.
CH471052 Genomic DNA Translation: EAW79508.1
BC109275 mRNA Translation: AAI09276.1
BC109276 mRNA Translation: AAI09277.1
CCDSiCCDS33835.1
RefSeqiNP_057382.2, NM_016298.3
UniGeneiHs.272564

3D structure databases

ProteinModelPortaliQ9UH90
SMRiQ9UH90
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119698, 7 interactors
IntActiQ9UH90, 1 interactor
STRINGi9606.ENSP00000337510

PTM databases

iPTMnetiQ9UH90
PhosphoSitePlusiQ9UH90

Polymorphism and mutation databases

BioMutaiFBXO40
DMDMi124012094

Proteomic databases

PaxDbiQ9UH90
PeptideAtlasiQ9UH90
PRIDEiQ9UH90
ProteomicsDBi84285

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000338040; ENSP00000337510; ENSG00000163833
GeneIDi51725
KEGGihsa:51725
UCSCiuc003eeg.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51725
DisGeNETi51725
EuPathDBiHostDB:ENSG00000163833.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FBXO40
HGNCiHGNC:29816 FBXO40
MIMi609107 gene
neXtProtiNX_Q9UH90
OpenTargetsiENSG00000163833
PharmGKBiPA134971542

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEIY Eukaryota
ENOG410ZQ6P LUCA
GeneTreeiENSGT00410000025582
HOGENOMiHOG000059618
HOVERGENiHBG100177
InParanoidiQ9UH90
KOiK10315
OMAiHELLCPL
OrthoDBiEOG091G06SE
PhylomeDBiQ9UH90
TreeFamiTF343227

Enzyme and pathway databases

ReactomeiR-HSA-8951664 Neddylation
R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
51725

Protein Ontology

More...
PROi
PR:Q9UH90

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000163833 Expressed in 86 organ(s), highest expression level in deltoid
CleanExiHS_FBXO40
GenevisibleiQ9UH90 HS

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR031890 Fbxo30/Fbxo40
IPR008974 TRAF-like
IPR013083 Znf_RING/FYVE/PHD
IPR001293 Znf_TRAF
PANTHERiPTHR15933 PTHR15933, 1 hit
PfamiView protein in Pfam
PF15966 F-box_4, 1 hit
PF15965 zf-TRAF_2, 1 hit
SUPFAMiSSF49599 SSF49599, 1 hit
SSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit
PS50145 ZF_TRAF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFBX40_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UH90
Secondary accession number(s): B2RAX7, Q32M70, Q9ULM5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: January 23, 2007
Last modified: November 7, 2018
This is version 135 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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