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UniProtKB - Q9UH62 (ARMX3_HUMAN)

Entry version 159 (25 May 2022)
Sequence version 1 (01 May 2000)
Previous versions | rss
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Protein

Armadillo repeat-containing X-linked protein 3

Gene

ARMCX3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9UH62

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-9013404, RAC2 GTPase cycle

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9UH62

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Armadillo repeat-containing X-linked protein 3
Alternative name(s):
ARM protein lost in epithelial cancers on chromosome X 3
Short name:
Protein ALEX3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARMCX3
Synonyms:ALEX3
ORF Names:BM-017, UNQ2517/PRO6007
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24065, ARMCX3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		300364, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9UH62

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000102401

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 6Mitochondrial intermembraneBy similarity6
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 29Helical; Signal-anchorSequence analysisAdd BLAST23
Topological domaini30 – 379CytoplasmicBy similarityAdd BLAST350

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		51566

Open Targets

More...OpenTargetsi		ENSG00000102401

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134977725

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9UH62, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ARMCX3

Domain mapping of disease mutations (DMDM)

More...DMDMi		74753322

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001913661 – 379Armadillo repeat-containing X-linked protein 3Add BLAST379

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei61PhosphoserineCombined sources1
Modified residuei67PhosphoserineCombined sources1
Modified residuei72PhosphoserineCombined sources1
Modified residuei110PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9UH62

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9UH62

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9UH62

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9UH62

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9UH62

PeptideAtlas

More...PeptideAtlasi		Q9UH62

PRoteomics IDEntifications database

More...PRIDEi		Q9UH62

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		84277

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9UH62

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q9UH62

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9UH62

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000102401, Expressed in amniotic fluid and 247 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9UH62, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9UH62, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000102401, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via ARM domain) with MIRO1, MIRO2 and TRAK2. The interaction with Miro is calcium-dependent.

Interacts with SOX10.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119614, 122 interactors

Protein interaction database and analysis system

More...IntActi		Q9UH62, 28 interactors

Molecular INTeraction database

More...MINTi		Q9UH62

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000340672

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9UH62, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q9UH62

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9UH62

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati111 – 151ARM 1Sequence analysisAdd BLAST41
Repeati153 – 192ARM 2Sequence analysisAdd BLAST40
Repeati233 – 272ARM 3Sequence analysisAdd BLAST40

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 6Mitochondrion outer membrane (MOM)-targeting sequenceCurated6
Regioni26 – 37Mitochondrion outer membrane (MOM)-targeting sequenceCuratedAdd BLAST12
Regioni89 – 98Nuclear localization signalBy similarity10
Regioni95 – 116DisorderedSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eutherian X-chromosome-specific Armcx family.Curated

Keywords - Domaini

Repeat, Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502TCDI, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162753

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_037187_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9UH62

Identification of Orthologs from Complete Genome Data

More...OMAi		DSKSIVW

Database of Orthologous Groups

More...OrthoDBi		860703at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9UH62

TreeFam database of animal gene trees

More...TreeFami		TF335652

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011989, ARM-like
IPR006911, ARM-rpt_dom
IPR016024, ARM-type_fold
IPR000225, Armadillo

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04826, Arm_2, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50176, ARM_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9UH62-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGYARKVGWV TAGLVIGAGA CYCIYRLTRG RKQNKEKMAE GGSGDVDDAG 
        60         70         80         90        100
DCSGARYNDW SDDDDDSNES KSIVWYPPWA RIGTEAGTRA RARARARATR 
       110        120        130        140        150
ARRAVQKRAS PNSDDTVLSP QELQKVLCLV EMSEKPYILE AALIALGNNA 
       160        170        180        190        200
AYAFNRDIIR DLGGLPIVAK ILNTRDPIVK EKALIVLNNL SVNAENQRRL 
       210        220        230        240        250
KVYMNQVCDD TITSRLNSSV QLAGLRLLTN MTVTNEYQHM LANSISDFFR 
       260        270        280        290        300
LFSAGNEETK LQVLKLLLNL AENPAMTREL LRAQVPSSLG SLFNKKENKE 
       310        320        330        340        350
VILKLLVIFE NINDNFKWEE NEPTQNQFGE GSLFFFLKEF QVCADKVLGI 
       360        370 
ESHHDFLVKV KVGKFMAKLA EHMFPKSQE
Length:379
Mass (Da):42,501
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB715D7F83DF4DFB0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BV87H3BV87_HUMAN
Armadillo repeat-containing X-linke...
ARMCX3
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BM63H3BM63_HUMAN
Armadillo repeat-containing X-linke...
ARMCX3
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti310E → V in BAD96375 (Ref. 5) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB039669 mRNA Translation: BAA94602.1
AF211175 mRNA Translation: AAF24487.1
AF208859 mRNA Translation: AAF64273.1
AY359079 mRNA Translation: AAQ89438.1
AK222655 mRNA Translation: BAD96375.1
CR933656 mRNA Translation: CAI45955.1
AL121883 Genomic DNA Translation: CAI42939.1
BC005194 mRNA Translation: AAH05194.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14489.1

NCBI Reference Sequences

More...RefSeqi		NP_057691.1, NM_016607.3
NP_808816.1, NM_177947.2
NP_808817.1, NM_177948.2
XP_005262198.1, XM_005262141.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000341189.8; ENSP00000340672.4; ENSG00000102401.20
ENST00000471229.7; ENSP00000454483.1; ENSG00000102401.20
ENST00000537169.1; ENSP00000439032.1; ENSG00000102401.20

Database of genes from NCBI RefSeq genomes

More...GeneIDi		51566

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:51566

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000471229.7; ENSP00000454483.1; NM_177947.3; NP_808816.1

UCSC genome browser

More...UCSCi		uc004ehz.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB039669 mRNA Translation: BAA94602.1
AF211175 mRNA Translation: AAF24487.1
AF208859 mRNA Translation: AAF64273.1
AY359079 mRNA Translation: AAQ89438.1
AK222655 mRNA Translation: BAD96375.1
CR933656 mRNA Translation: CAI45955.1
AL121883 Genomic DNA Translation: CAI42939.1
BC005194 mRNA Translation: AAH05194.1
CCDSiCCDS14489.1
RefSeqiNP_057691.1, NM_016607.3
NP_808816.1, NM_177947.2
NP_808817.1, NM_177948.2
XP_005262198.1, XM_005262141.2

3D structure databases

AlphaFoldDBiQ9UH62
SMRiQ9UH62
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119614, 122 interactors
IntActiQ9UH62, 28 interactors
MINTiQ9UH62
STRINGi9606.ENSP00000340672

PTM databases

iPTMnetiQ9UH62
MetOSiteiQ9UH62
PhosphoSitePlusiQ9UH62

Genetic variation databases

BioMutaiARMCX3
DMDMi74753322

Proteomic databases

EPDiQ9UH62
jPOSTiQ9UH62
MassIVEiQ9UH62
MaxQBiQ9UH62
PaxDbiQ9UH62
PeptideAtlasiQ9UH62
PRIDEiQ9UH62
ProteomicsDBi84277

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		378, 244 antibodies from 29 providers

The DNASU plasmid repository

More...DNASUi		51566

Genome annotation databases

EnsembliENST00000341189.8; ENSP00000340672.4; ENSG00000102401.20
ENST00000471229.7; ENSP00000454483.1; ENSG00000102401.20
ENST00000537169.1; ENSP00000439032.1; ENSG00000102401.20
GeneIDi51566
KEGGihsa:51566
MANE-SelectiENST00000471229.7; ENSP00000454483.1; NM_177947.3; NP_808816.1
UCSCiuc004ehz.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51566
DisGeNETi51566

GeneCards: human genes, protein and diseases

More...GeneCardsi		ARMCX3
HGNCiHGNC:24065, ARMCX3
HPAiENSG00000102401, Low tissue specificity
MIMi300364, gene
neXtProtiNX_Q9UH62
OpenTargetsiENSG00000102401
PharmGKBiPA134977725
VEuPathDBiHostDB:ENSG00000102401

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502TCDI, Eukaryota
GeneTreeiENSGT00940000162753
HOGENOMiCLU_037187_0_0_1
InParanoidiQ9UH62
OMAiDSKSIVW
OrthoDBi860703at2759
PhylomeDBiQ9UH62
TreeFamiTF335652

Enzyme and pathway databases

PathwayCommonsiQ9UH62
ReactomeiR-HSA-9013404, RAC2 GTPase cycle
SignaLinkiQ9UH62

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		51566, 11 hits in 702 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ARMCX3, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ARMCX3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		51566
PharosiQ9UH62, Tdark

Protein Ontology

More...PROi		PR:Q9UH62
RNActiQ9UH62, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000102401, Expressed in amniotic fluid and 247 other tissues
ExpressionAtlasiQ9UH62, baseline and differential
GenevisibleiQ9UH62, HS

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR011989, ARM-like
IPR006911, ARM-rpt_dom
IPR016024, ARM-type_fold
IPR000225, Armadillo
PfamiView protein in Pfam
PF04826, Arm_2, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176, ARM_REPEAT, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARMX3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UH62
Secondary accession number(s): Q53HC6, Q7LCF5, Q9NPE4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: May 1, 2000
Last modified: May 25, 2022
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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