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Entry version 185 (02 Jun 2021)
Sequence version 2 (05 Dec 2018)
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Protein

Zinc finger CCCH domain-containing protein 7B

Gene

ZC3H7B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 'ATA(A/T)' motif in the apical loop.

1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri484 – 508C3H1-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri616 – 638C3H1-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri754 – 782C3H1-type 3PROSITE-ProRule annotationAdd BLAST29
Zinc fingeri842 – 866C2H2-typePROSITE-ProRule annotationAdd BLAST25
Zinc fingeri886 – 914C3H1-type 4PROSITE-ProRule annotationAdd BLAST29

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processHost-virus interaction
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q9UGR2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger CCCH domain-containing protein 7B
Alternative name(s):
Rotavirus 'X'-associated non-structural protein
Short name:
RoXaN
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZC3H7B
Synonyms:KIAA1031
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30869, ZC3H7B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618206, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UGR2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000100403.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi241 – 243DSS → AAA: Almost no effect on NSP3 binding. 1 Publication3
Mutagenesisi252 – 254LDD → AAA: Complete loss of NSP3 binding. 1 Publication3

Organism-specific databases

DisGeNET

More...
DisGeNETi
23264

Open Targets

More...
OpenTargetsi
ENSG00000100403

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670533

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UGR2, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZC3H7B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
20455239

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001063221 – 977Zinc finger CCCH domain-containing protein 7BAdd BLAST977

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei217PhosphoserineCombined sources1
Modified residuei364PhosphoserineCombined sources1
Modified residuei367PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UGR2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UGR2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UGR2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UGR2

PeptideAtlas

More...
PeptideAtlasi
Q9UGR2

PRoteomics IDEntifications database

More...
PRIDEi
Q9UGR2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UGR2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UGR2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000100403, Expressed in amniotic fluid and 251 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UGR2, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000100403, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

(Microbial infection) Interacts (via LD motif) with rotavirus A NSP3 (via the coiled-coil region).

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
116866, 29 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UGR2, 11 interactors

Molecular INTeraction database

More...
MINTi
Q9UGR2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000345793

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9UGR2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UGR2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1 – 27TPR 1Sequence analysisAdd BLAST27
Repeati36 – 69TPR 2PROSITE-ProRule annotationAdd BLAST34
Repeati82 – 115TPR 3PROSITE-ProRule annotationAdd BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni365 – 403DisorderedSequence analysisAdd BLAST39

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi248 – 256LD motif; interaction with NSP39

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri484 – 508C3H1-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri616 – 638C3H1-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri754 – 782C3H1-type 3PROSITE-ProRule annotationAdd BLAST29
Zinc fingeri842 – 866C2H2-typePROSITE-ProRule annotationAdd BLAST25
Zinc fingeri886 – 914C3H1-type 4PROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Repeat, TPR repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QVIS, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018542

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012672_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UGR2

Identification of Orthologs from Complete Genome Data

More...
OMAi
SYPQQYD

Database of Orthologous Groups

More...
OrthoDBi
369231at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UGR2

TreeFam database of animal gene trees

More...
TreeFami
TF329017

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
IPR039691, ZC3H7A/B
IPR036236, Znf_C2H2_sf
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf

The PANTHER Classification System

More...
PANTHERi
PTHR14928, PTHR14928, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13181, TPR_8, 1 hit
PF00642, zf-CCCH, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028, TPR, 2 hits
SM00356, ZnF_C3H1, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452, SSF48452, 1 hit
SSF57667, SSF57667, 1 hit
SSF90229, SSF90229, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50005, TPR, 2 hits
PS50293, TPR_REGION, 1 hit
PS50103, ZF_C3H1, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UGR2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERQKRKADI EKGLQFIQST LPLKQEEYEA FLLKLVQNLF AEGNDLFREK
60 70 80 90 100
DYKQALVQYM EGLNVADYAA SDQVALPREL LCKLHVNRAA CYFTMGLYEK
110 120 130 140 150
ALEDSEKALG LDSESIRALF RKARALNELG RHKEAYECSS RCSLALPHDE
160 170 180 190 200
SVTQLGQELA QKLGLRVRKA YKRPQELETF SLLSNGTAAG VADQGTSNGL
210 220 230 240 250
GSIDDIETDC YVDPRGSPAL LPSTPTMPLF PHVLDLLAPL DSSRTLPSTD
260 270 280 290 300
SLDDFSDGDV FGPELDTLLD SLSLVQGGLS GSGVPSELPQ LIPVFPGGTP
310 320 330 340 350
LLPPVVGGSI PVSSPLPPAS FGLVMDPSKK LAASVLDALD PPGPTLDPLD
360 370 380 390 400
LLPYSETRLD ALDSFGSTRG SLDKPDSFME ETNSQDHRPP SGAQKPAPSP
410 420 430 440 450
EPCMPNTALL IKNPLAATHE FKQACQLCYP KTGPRAGDYT YREGLEHKCK
460 470 480 490 500
RDILLGRLRS SEDQTWKRIR PRPTKTSFVG SYYLCKDMIN KQDCKYGDNC
510 520 530 540 550
TFAYHQEEID VWTEERKGTL NRDLLFDPLG GVKRGSLTIA KLLKEHQGIF
560 570 580 590 600
TFLCEICFDS KPRIISKGTK DSPSVCSNLA AKHSFYNNKC LVHIVRSTSL
610 620 630 640 650
KYSKIRQFQE HFQFDVCRHE VRYGCLREDS CHFAHSFIEL KVWLLQQYSG
660 670 680 690 700
MTHEDIVQES KKYWQQMEAH AGKASSSMGA PRTHGPSTFD LQMKFVCGQC
710 720 730 740 750
WRNGQVVEPD KDLKYCSAKA RHCWTKERRV LLVMSKAKRK WVSVRPLPSI
760 770 780 790 800
RNFPQQYDLC IHAQNGRKCQ YVGNCSFAHS PEERDMWTFM KENKILDMQQ
810 820 830 840 850
TYDMWLKKHN PGKPGEGTPI SSREGEKQIQ MPTDYADIMM GYHCWLCGKN
860 870 880 890 900
SNSKKQWQQH IQSEKHKEKV FTSDSDASGW AFRFPMGEFR LCDRLQKGKA
910 920 930 940 950
CPDGDKCRCA HGQEELNEWL DRREVLKQKL AKARKDMLLC PRDDDFGKYN
960 970
FLLQEDGDLA GATPEAPAAA ATATTGE
Length:977
Mass (Da):109,858
Last modified:December 5, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBE3F8AEEC89D096D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti38 – 39NL → LE in BAA82983 (PubMed:10470851).Curated2
Sequence conflicti88R → K in AAF05541 (Ref. 4) Curated1
Sequence conflicti216G → A in AAF05541 (Ref. 4) Curated1
Sequence conflicti231P → T in AAI52559 (PubMed:15489334).Curated1
Sequence conflicti370G → V in AAF05541 (Ref. 4) Curated1
Sequence conflicti390P → T in AAI52559 (PubMed:15489334).Curated1
Sequence conflicti660S → F in AAF05541 (Ref. 4) Curated1
Sequence conflicti902P → L in AAI52559 (PubMed:15489334).Curated1
Sequence conflicti955E → G in BAG37501 (PubMed:14702039).Curated1
Sequence conflicti955E → G in AAI52559 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_054313363D → N. Corresponds to variant dbSNP:rs9607793Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK315009 mRNA Translation: BAG37501.1
AL035659 Genomic DNA No translation available.
BC024313 mRNA Translation: AAH24313.2
BC152558 mRNA Translation: AAI52559.1
AF188530 mRNA Translation: AAF05541.1
AB028954 mRNA Translation: BAA82983.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14013.1

NCBI Reference Sequences

More...
RefSeqi
NP_060060.3, NM_017590.5

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000352645; ENSP00000345793; ENSG00000100403

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23264

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23264

UCSC genome browser

More...
UCSCi
uc003azw.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315009 mRNA Translation: BAG37501.1
AL035659 Genomic DNA No translation available.
BC024313 mRNA Translation: AAH24313.2
BC152558 mRNA Translation: AAI52559.1
AF188530 mRNA Translation: AAF05541.1
AB028954 mRNA Translation: BAA82983.1
CCDSiCCDS14013.1
RefSeqiNP_060060.3, NM_017590.5

3D structure databases

SMRiQ9UGR2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi116866, 29 interactors
IntActiQ9UGR2, 11 interactors
MINTiQ9UGR2
STRINGi9606.ENSP00000345793

PTM databases

iPTMnetiQ9UGR2
PhosphoSitePlusiQ9UGR2

Genetic variation databases

BioMutaiZC3H7B
DMDMi20455239

Proteomic databases

EPDiQ9UGR2
jPOSTiQ9UGR2
MassIVEiQ9UGR2
PaxDbiQ9UGR2
PeptideAtlasiQ9UGR2
PRIDEiQ9UGR2

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
203, 112 antibodies

The DNASU plasmid repository

More...
DNASUi
23264

Genome annotation databases

EnsembliENST00000352645; ENSP00000345793; ENSG00000100403
GeneIDi23264
KEGGihsa:23264
UCSCiuc003azw.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23264
DisGeNETi23264

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZC3H7B
HGNCiHGNC:30869, ZC3H7B
HPAiENSG00000100403, Low tissue specificity
MIMi618206, gene
neXtProtiNX_Q9UGR2
OpenTargetsiENSG00000100403
PharmGKBiPA142670533
VEuPathDBiHostDB:ENSG00000100403.11

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QVIS, Eukaryota
GeneTreeiENSGT00390000018542
HOGENOMiCLU_012672_0_0_1
InParanoidiQ9UGR2
OMAiSYPQQYD
OrthoDBi369231at2759
PhylomeDBiQ9UGR2
TreeFamiTF329017

Enzyme and pathway databases

PathwayCommonsiQ9UGR2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
23264, 7 hits in 1000 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZC3H7B, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
Roxan_(protein)

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
23264
PharosiQ9UGR2, Tbio

Protein Ontology

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PROi
PR:Q9UGR2
RNActiQ9UGR2, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000100403, Expressed in amniotic fluid and 251 other tissues
GenevisibleiQ9UGR2, HS

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
IPR039691, ZC3H7A/B
IPR036236, Znf_C2H2_sf
IPR000571, Znf_CCCH
IPR036855, Znf_CCCH_sf
PANTHERiPTHR14928, PTHR14928, 1 hit
PfamiView protein in Pfam
PF13181, TPR_8, 1 hit
PF00642, zf-CCCH, 2 hits
SMARTiView protein in SMART
SM00028, TPR, 2 hits
SM00356, ZnF_C3H1, 4 hits
SUPFAMiSSF48452, SSF48452, 1 hit
SSF57667, SSF57667, 1 hit
SSF90229, SSF90229, 2 hits
PROSITEiView protein in PROSITE
PS50005, TPR, 2 hits
PS50293, TPR_REGION, 1 hit
PS50103, ZF_C3H1, 4 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZ3H7B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UGR2
Secondary accession number(s): A7YY88
, B2RCA4, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: December 5, 2018
Last modified: June 2, 2021
This is version 185 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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