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Entry version 162 (13 Feb 2019)
Sequence version 2 (26 Jun 2007)
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Protein

Solute carrier family 2, facilitated glucose transporter member 6

Gene

SLC2A6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Facilitative glucose transporter; binds cytochalasin B with low affinity.

Caution

Has been described as GLUT9 in literature, but this gene name has already been used for SLC2A9.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei418MonosaccharideBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • carbohydrate:proton symporter activity Source: GO_Central
  • D-glucose transmembrane transporter activity Source: Reactome
  • glucose transmembrane transporter activity Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-189200 Cellular hexose transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.1.1.88 the major facilitator superfamily (mfs)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 2, facilitated glucose transporter member 6
Alternative name(s):
Glucose transporter type 6
Short name:
GLUT-6
Glucose transporter type 9
Short name:
GLUT-9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC2A6
Synonyms:GLUT9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000160326.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11011 SLC2A6

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606813 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UGQ3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 37CytoplasmicSequence analysisAdd BLAST37
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei38 – 58Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini59 – 81ExtracellularSequence analysisAdd BLAST23
Transmembranei82 – 102Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini103 – 111CytoplasmicSequence analysis9
Transmembranei112 – 132Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini133 – 140ExtracellularSequence analysis8
Transmembranei141 – 161Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini162 – 168CytoplasmicSequence analysis7
Transmembranei169 – 189Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini190 – 194ExtracellularSequence analysis5
Transmembranei195 – 215Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini216 – 289CytoplasmicSequence analysisAdd BLAST74
Transmembranei290 – 310Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini311 – 314ExtracellularSequence analysis4
Transmembranei315 – 335Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini336 – 339CytoplasmicSequence analysis4
Transmembranei340 – 360Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini361 – 395ExtracellularSequence analysisAdd BLAST35
Transmembranei396 – 416Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini417 – 435CytoplasmicSequence analysisAdd BLAST19
Transmembranei436 – 456Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini457 – 462ExtracellularSequence analysis6
Transmembranei463 – 483Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini484 – 507CytoplasmicSequence analysisAdd BLAST24

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
11182

Open Targets

More...
OpenTargetsi
ENSG00000160326

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA35881

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB09502 Fludeoxyglucose F-18

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC2A6

Domain mapping of disease mutations (DMDM)

More...
DMDMi
150421565

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000503731 – 507Solute carrier family 2, facilitated glucose transporter member 6Add BLAST507

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei23PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi370N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UGQ3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UGQ3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UGQ3

PeptideAtlas

More...
PeptideAtlasi
Q9UGQ3

PRoteomics IDEntifications database

More...
PRIDEi
Q9UGQ3

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84259
84260 [Q9UGQ3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UGQ3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UGQ3

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9UGQ3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in brain, spleen and peripheral blood leukocytes.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000160326 Expressed in 163 organ(s), highest expression level in cerebellar vermis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UGQ3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UGQ3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB046014
HPA042272

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116352, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UGQ3, 2 interactors

Molecular INTeraction database

More...
MINTi
Q9UGQ3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000360966

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UGQ3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni286 – 292Monosaccharide bindingBy similarity7

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi5 – 6Dileucine internalization motifSequence analysis2

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0254 Eukaryota
ENOG410XNQK LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159976

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000202868

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG104335

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UGQ3

KEGG Orthology (KO)

More...
KOi
K08144

Identification of Orthologs from Complete Genome Data

More...
OMAi
IMFAANL

Database of Orthologous Groups

More...
OrthoDBi
430696at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UGQ3

TreeFam database of animal gene trees

More...
TreeFami
TF325324

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06174 MFS, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083 Sugar_tr, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00171 SUGRTRNSPORT

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00879 SP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UGQ3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQEPLLGAEG PDYDTFPEKP PPSPGDRARV GTLQNKRVFL ATFAAVLGNF
60 70 80 90 100
SFGYALVYTS PVIPALERSL DPDLHLTKSQ ASWFGSVFTL GAAAGGLSAM
110 120 130 140 150
ILNDLLGRKL SIMFSAVPSA AGYALMAGAH GLWMLLLGRT LTGFAGGLTA
160 170 180 190 200
ACIPVYVSEI APPGVRGALG ATPQLMAVFG SLSLYALGLL LPWRWLAVAG
210 220 230 240 250
EAPVLIMILL LSFMPNSPRF LLSRGRDEEA LRALAWLRGT DVDVHWEFEQ
260 270 280 290 300
IQDNVRRQSS RVSWAEARAP HVCRPITVAL LMRLLQQLTG ITPILVYLQS
310 320 330 340 350
IFDSTAVLLP PKDDAAIVGA VRLLSVLIAA LTMDLAGRKV LLFVSAAIMF
360 370 380 390 400
AANLTLGLYI HFGPRPLSPN STAGLESESW GDLAQPLAAP AGYLTLVPLL
410 420 430 440 450
ATMLFIMGYA VGWGPITWLL MSEVLPLRAR GVASGLCVLA SWLTAFVLTK
460 470 480 490 500
SFLPVVSTFG LQVPFFFFAA ICLVSLVFTG CCVPETKGRS LEQIESFFRT

GRRSFLR
Length:507
Mass (Da):54,539
Last modified:June 26, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i32C6E2EB11588477
GO
Isoform 2 (identifier: Q9UGQ3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     346-407: Missing.

Show »
Length:445
Mass (Da):48,041
Checksum:iBF37DC0C313A32CE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z2F6F2Z2F6_HUMAN
Solute carrier family 2, facilitate...
SLC2A6
219Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z3K7F2Z3K7_HUMAN
Solute carrier family 2, facilitate...
SLC2A6
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_025426500T → M2 PublicationsCorresponds to variant dbSNP:rs3094378Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_041402346 – 407Missing in isoform 2. 1 PublicationAdd BLAST62

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Y17803 mRNA Translation: CAB96996.1
AJ011372 mRNA Translation: CAB66155.1
AK074927 mRNA Translation: BAC11297.1
AK222919 mRNA Translation: BAD96639.1
AK074836 mRNA Translation: BAC11235.1
AL593848 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW88093.1
CH471090 Genomic DNA Translation: EAW88094.1
BC013740 mRNA Translation: AAH13740.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS48052.1 [Q9UGQ3-2]
CCDS6975.1 [Q9UGQ3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001138571.1, NM_001145099.1 [Q9UGQ3-2]
NP_060055.2, NM_017585.3 [Q9UGQ3-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.244378

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000371897; ENSP00000360964; ENSG00000160326 [Q9UGQ3-2]
ENST00000371899; ENSP00000360966; ENSG00000160326 [Q9UGQ3-1]
ENST00000625425; ENSP00000486637; ENSG00000281165 [Q9UGQ3-2]
ENST00000626271; ENSP00000487067; ENSG00000281165 [Q9UGQ3-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
11182

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:11182

UCSC genome browser

More...
UCSCi
uc004cee.4 human [Q9UGQ3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y17803 mRNA Translation: CAB96996.1
AJ011372 mRNA Translation: CAB66155.1
AK074927 mRNA Translation: BAC11297.1
AK222919 mRNA Translation: BAD96639.1
AK074836 mRNA Translation: BAC11235.1
AL593848 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW88093.1
CH471090 Genomic DNA Translation: EAW88094.1
BC013740 mRNA Translation: AAH13740.1
CCDSiCCDS48052.1 [Q9UGQ3-2]
CCDS6975.1 [Q9UGQ3-1]
RefSeqiNP_001138571.1, NM_001145099.1 [Q9UGQ3-2]
NP_060055.2, NM_017585.3 [Q9UGQ3-1]
UniGeneiHs.244378

3D structure databases

ProteinModelPortaliQ9UGQ3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116352, 3 interactors
IntActiQ9UGQ3, 2 interactors
MINTiQ9UGQ3
STRINGi9606.ENSP00000360966

Chemistry databases

DrugBankiDB09502 Fludeoxyglucose F-18

Protein family/group databases

TCDBi2.A.1.1.88 the major facilitator superfamily (mfs)

PTM databases

iPTMnetiQ9UGQ3
PhosphoSitePlusiQ9UGQ3
SwissPalmiQ9UGQ3

Polymorphism and mutation databases

BioMutaiSLC2A6
DMDMi150421565

Proteomic databases

EPDiQ9UGQ3
jPOSTiQ9UGQ3
PaxDbiQ9UGQ3
PeptideAtlasiQ9UGQ3
PRIDEiQ9UGQ3
ProteomicsDBi84259
84260 [Q9UGQ3-2]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
11182
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000371897; ENSP00000360964; ENSG00000160326 [Q9UGQ3-2]
ENST00000371899; ENSP00000360966; ENSG00000160326 [Q9UGQ3-1]
ENST00000625425; ENSP00000486637; ENSG00000281165 [Q9UGQ3-2]
ENST00000626271; ENSP00000487067; ENSG00000281165 [Q9UGQ3-1]
GeneIDi11182
KEGGihsa:11182
UCSCiuc004cee.4 human [Q9UGQ3-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
11182
DisGeNETi11182
EuPathDBiHostDB:ENSG00000160326.13

GeneCards: human genes, protein and diseases

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GeneCardsi
SLC2A6

H-Invitational Database, human transcriptome db

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H-InvDBi
HIX0008509
HGNCiHGNC:11011 SLC2A6
HPAiCAB046014
HPA042272
MIMi606813 gene
neXtProtiNX_Q9UGQ3
OpenTargetsiENSG00000160326
PharmGKBiPA35881

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0254 Eukaryota
ENOG410XNQK LUCA
GeneTreeiENSGT00940000159976
HOGENOMiHOG000202868
HOVERGENiHBG104335
InParanoidiQ9UGQ3
KOiK08144
OMAiIMFAANL
OrthoDBi430696at2759
PhylomeDBiQ9UGQ3
TreeFamiTF325324

Enzyme and pathway databases

ReactomeiR-HSA-189200 Cellular hexose transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SLC2A6 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
SLC2A6

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
11182

Protein Ontology

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PROi
PR:Q9UGQ3

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000160326 Expressed in 163 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasiQ9UGQ3 baseline and differential
GenevisibleiQ9UGQ3 HS

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGTR6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UGQ3
Secondary accession number(s): A6NNU6, Q5SXD7, Q8NCC2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: June 26, 2007
Last modified: February 13, 2019
This is version 162 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
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