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Protein

ATP-binding cassette sub-family F member 2

Gene

ABCF2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks transmembrane domains and is probably not involved in transport.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi118 – 125ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi430 – 437ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATPase activity Source: InterPro
  • ATP binding Source: ProtInc
  • transporter activity Source: ProtInc

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATP-binding cassette sub-family F member 2
Alternative name(s):
Iron-inhibited ABC transporter 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCF2
ORF Names:HUSSY-18
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000033050.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:71 ABCF2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612510 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UG63

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10061

Open Targets

More...
OpenTargetsi
ENSG00000033050

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24406

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...
DMDMi
12643306

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000933231 – 623ATP-binding cassette sub-family F member 2Add BLAST623

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei218PhosphothreonineCombined sources1
Modified residuei304N6-acetyllysineCombined sources1
Modified residuei512PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UG63

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UG63

PeptideAtlas

More...
PeptideAtlasi
Q9UG63

PRoteomics IDEntifications database

More...
PRIDEi
Q9UG63

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84202

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UG63

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UG63

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
Q9UG63

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000033050 Expressed in 219 organ(s), highest expression level in oocyte

CleanEx database of gene expression profiles

More...
CleanExi
HS_ABCF2

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UG63 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UG63 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB020682
HPA020091
HPA021815
HPA030388

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115372, 57 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9UG63

Protein interaction database and analysis system

More...
IntActi
Q9UG63, 22 interactors

Molecular INTeraction database

More...
MINTi
Q9UG63

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000222388

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UG63

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UG63

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini86 – 325ABC transporter 1PROSITE-ProRule annotationAdd BLAST240
Domaini396 – 613ABC transporter 2PROSITE-ProRule annotationAdd BLAST218

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0927 Eukaryota
COG0488 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00630000089910

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000271637

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG050440

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UG63

KEGG Orthology (KO)

More...
KOi
K06185

Identification of Orthologs from Complete Genome Data

More...
OMAi
SALQCVM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UG63

TreeFam database of animal gene trees

More...
TreeFami
TF105208

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR032781 ABC_tran_Xtn
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00005 ABC_tran, 2 hits
PF12848 ABC_tran_Xtn, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UG63-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPSDLAKKKA AKKKEAAKAR QRPRKGHEEN GDVVTEPQVA EKNEANGRET
60 70 80 90 100
TEVDLLTKEL EDFEMKKAAA RAVTGVLASH PNSTDVHIIN LSLTFHGQEL
110 120 130 140 150
LSDTKLELNS GRRYGLIGLN GIGKSMLLSA IGKREVPIPE HIDIYHLTRE
160 170 180 190 200
MPPSDKTPLH CVMEVDTERA MLEKEAERLA HEDAECEKLM ELYERLEELD
210 220 230 240 250
ADKAEMRASR ILHGLGFTPA MQRKKLKDFS GGWRMRVALA RALFIRPFML
260 270 280 290 300
LLDEPTNHLD LDACVWLEEE LKTFKRILVL VSHSQDFLNG VCTNIIHMHN
310 320 330 340 350
KKLKYYTGNY DQYVKTRLEL EENQMKRFHW EQDQIAHMKN YIARFGHGSA
360 370 380 390 400
KLARQAQSKE KTLQKMMASG LTERVVSDKT LSFYFPPCGK IPPPVIMVQN
410 420 430 440 450
VSFKYTKDGP CIYNNLEFGI DLDTRVALVG PNGAGKSTLL KLLTGELLPT
460 470 480 490 500
DGMIRKHSHV KIGRYHQHLQ EQLDLDLSPL EYMMKCYPEI KEKEEMRKII
510 520 530 540 550
GRYGLTGKQQ VSPIRNLSDG QKCRVCLAWL AWQNPHMLFL DEPTNHLDIE
560 570 580 590 600
TIDALADAIN EFEGGMMLVS HDFRLIQQVA QEIWVCEKQT ITKWPGDILA
610 620
YKEHLKSKLV DEEPQLTKRT HNV
Length:623
Mass (Da):71,290
Last modified:January 24, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i702A968BCF8061AE
GO
Isoform 2 (identifier: Q9UG63-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     623-623: V → VCTLTLASLPRP

Show »
Length:634
Mass (Da):72,444
Checksum:iFCB0633F0D9BA0DC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JZV3C9JZV3_HUMAN
ATP-binding cassette sub-family F m...
ABCF2
287Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JHK9C9JHK9_HUMAN
ATP-binding cassette sub-family F m...
ABCF2
240Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti39V → A in AAG13902 (PubMed:10944468).Curated1
Sequence conflicti39V → A in AAG13903 (PubMed:10944468).Curated1
Sequence conflicti74T → A in CAA06290 (PubMed:11124703).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_054715623V → VCTLTLASLPRP in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF261091 mRNA Translation: AAG13902.1
AF261092 mRNA Translation: AAG13903.1
BT007451 mRNA Translation: AAP36119.1
AL050291 mRNA Translation: CAB43392.1
AC021097 Genomic DNA Translation: AAS00378.1
AC021097 Genomic DNA Translation: AAS00379.1
CH471173 Genomic DNA Translation: EAW54014.1
CH471173 Genomic DNA Translation: EAW54016.1
CH471173 Genomic DNA Translation: EAW54017.1
BC001661 mRNA Translation: AAH01661.1
AJ005016 mRNA Translation: CAA06290.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5922.1 [Q9UG63-2]
CCDS5923.1 [Q9UG63-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
T08810

NCBI Reference Sequences

More...
RefSeqi
NP_005683.2, NM_005692.4 [Q9UG63-2]
NP_009120.1, NM_007189.2 [Q9UG63-1]
XP_016867128.1, XM_017011639.1 [Q9UG63-1]
XP_016867129.1, XM_017011640.1 [Q9UG63-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.654958

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000287844; ENSP00000287844; ENSG00000033050 [Q9UG63-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10061

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10061

UCSC genome browser

More...
UCSCi
uc003wjo.3 human [Q9UG63-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

ABCMdb

Database for mutations in ABC proteins

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF261091 mRNA Translation: AAG13902.1
AF261092 mRNA Translation: AAG13903.1
BT007451 mRNA Translation: AAP36119.1
AL050291 mRNA Translation: CAB43392.1
AC021097 Genomic DNA Translation: AAS00378.1
AC021097 Genomic DNA Translation: AAS00379.1
CH471173 Genomic DNA Translation: EAW54014.1
CH471173 Genomic DNA Translation: EAW54016.1
CH471173 Genomic DNA Translation: EAW54017.1
BC001661 mRNA Translation: AAH01661.1
AJ005016 mRNA Translation: CAA06290.1
CCDSiCCDS5922.1 [Q9UG63-2]
CCDS5923.1 [Q9UG63-1]
PIRiT08810
RefSeqiNP_005683.2, NM_005692.4 [Q9UG63-2]
NP_009120.1, NM_007189.2 [Q9UG63-1]
XP_016867128.1, XM_017011639.1 [Q9UG63-1]
XP_016867129.1, XM_017011640.1 [Q9UG63-1]
UniGeneiHs.654958

3D structure databases

ProteinModelPortaliQ9UG63
SMRiQ9UG63
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115372, 57 interactors
CORUMiQ9UG63
IntActiQ9UG63, 22 interactors
MINTiQ9UG63
STRINGi9606.ENSP00000222388

PTM databases

iPTMnetiQ9UG63
PhosphoSitePlusiQ9UG63

Polymorphism and mutation databases

DMDMi12643306

Proteomic databases

EPDiQ9UG63
PaxDbiQ9UG63
PeptideAtlasiQ9UG63
PRIDEiQ9UG63
ProteomicsDBi84202

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
10061
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000287844; ENSP00000287844; ENSG00000033050 [Q9UG63-1]
GeneIDi10061
KEGGihsa:10061
UCSCiuc003wjo.3 human [Q9UG63-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10061
DisGeNETi10061
EuPathDBiHostDB:ENSG00000033050.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ABCF2
HGNCiHGNC:71 ABCF2
HPAiCAB020682
HPA020091
HPA021815
HPA030388
MIMi612510 gene
neXtProtiNX_Q9UG63
OpenTargetsiENSG00000033050
PharmGKBiPA24406

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0927 Eukaryota
COG0488 LUCA
GeneTreeiENSGT00630000089910
HOGENOMiHOG000271637
HOVERGENiHBG050440
InParanoidiQ9UG63
KOiK06185
OMAiSALQCVM
PhylomeDBiQ9UG63
TreeFamiTF105208

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ABCF2 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
ABCF2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10061
PMAP-CutDBiQ9UG63

Protein Ontology

More...
PROi
PR:Q9UG63

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000033050 Expressed in 219 organ(s), highest expression level in oocyte
CleanExiHS_ABCF2
ExpressionAtlasiQ9UG63 baseline and differential
GenevisibleiQ9UG63 HS

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR032781 ABC_tran_Xtn
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 2 hits
PF12848 ABC_tran_Xtn, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABCF2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UG63
Secondary accession number(s): O60864
, Q75MJ0, Q75MJ1, Q96TE8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: January 24, 2001
Last modified: December 5, 2018
This is version 162 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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