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Entry version 143 (03 Jul 2019)
Sequence version 4 (21 Mar 2012)
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Protein

RIMS-binding protein 3A

Gene

RIMBP3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Spermatogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RIMS-binding protein 3A
Short name:
RIM-BP3.A
Alternative name(s):
RIMS-binding protein 3.1
Short name:
RIM-BP3.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RIMBP3
Synonyms:KIAA1666, RIMBP3A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29344 RIMBP3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612699 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UFD9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000275793

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RIMBP3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
380865484

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002595971 – 1639RIMS-binding protein 3AAdd BLAST1639

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UFD9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UFD9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UFD9

PeptideAtlas

More...
PeptideAtlasi
Q9UFD9

PRoteomics IDEntifications database

More...
PRIDEi
Q9UFD9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84178

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UFD9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UFD9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000275793 Expressed in 32 organ(s), highest expression level in testis

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UFD9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA001183

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with LRGUK (via guanylate kinase-like domain).

Interacts (via C-terminus) with HOOK1 (via coiled-coil region).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124503, 22 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9UFD9

Protein interaction database and analysis system

More...
IntActi
Q9UFD9, 32 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000483386

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11639
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UFD9

Database of comparative protein structure models

More...
ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9UFD9

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini832 – 899SH3 1PROSITE-ProRule annotationAdd BLAST68
Domaini995 – 1083Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST89
Domaini1088 – 1184Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST97
Domaini1452 – 1520SH3 2PROSITE-ProRule annotationAdd BLAST69
Domaini1569 – 1636SH3 3PROSITE-ProRule annotationAdd BLAST68

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili21 – 143Sequence analysisAdd BLAST123
Coiled coili409 – 442Sequence analysisAdd BLAST34
Coiled coili480 – 619Sequence analysisAdd BLAST140

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi30 – 137Arg-richAdd BLAST108
Compositional biasi312 – 366Pro-richAdd BLAST55

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RIMBP family.Curated

Keywords - Domaini

Coiled coil, Repeat, SH3 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3632 Eukaryota
ENOG410XZ8W LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183203

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000090231

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UFD9

Identification of Orthologs from Complete Genome Data

More...
OMAi
AQIPEDC

Database of Orthologous Groups

More...
OrthoDBi
102427at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UFD9

TreeFam database of animal gene trees

More...
TreeFami
TF316230

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR040325 RIMBP1/2/3
IPR035515 Rimbp3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain

The PANTHER Classification System

More...
PANTHERi
PTHR14234 PTHR14234, 1 hit
PTHR14234:SF21 PTHR14234:SF21, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07653 SH3_2, 1 hit
PF14604 SH3_9, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00326 SH3, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 1 hit
SSF50044 SSF50044, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853 FN3, 2 hits
PS50002 SH3, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UFD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKDSPSPLG ASPKKPGCSS PAAAVLENQR RELEKLRAEL EAERAGWRAE
60 70 80 90 100
RRRFAARERQ LREEAERERR QLADRLRSKW EAQRSRELRQ LQEEMQRERE
110 120 130 140 150
AEIRQLLRWK EAEQRQLQQL LHRERDGVVR QARELQRQLA EELVNRGHCS
160 170 180 190 200
RPGASEVSAA QCRCRLQEVL AQLRWQTDGE QAARIRYLQA ALEVERQLFL
210 220 230 240 250
KYILAHFRGH PALSGSPDPQ AVHSLEEPLP QTSSGSCHAP KPACQLGSLD
260 270 280 290 300
SLSAEVGVRS RSLGLVSSAC SSSPDGLLST HASSLDCFAP ACSRSLDSTR
310 320 330 340 350
SLPKASKSEE RPSSPDTSTP GSRRLSPPPS PLPPPPPPSA HRKLSNPRGG
360 370 380 390 400
EGSESQPCEV LTPSPPGLGH HELIKLNWLL AKALWVLARR CYTLQAENKQ
410 420 430 440 450
LRRAGCPYQA DEKVKRLKVK RAELTGLARR LADRARKLQE TNLRAVSAPI
460 470 480 490 500
PGESCAGLEL CQVFARQRAR DLSEQASAPL AKDKQIEELR QECHLLQARV
510 520 530 540 550
ASGPCSDLHT GRGGPCTQWL NVRDLDRLQR ESQREVLRLQ RQLMLQQGNG
560 570 580 590 600
GAWPEAGGQS ATCEEVRRQM LALERELDQR RRECQELGAQ AAPARRRGEE
610 620 630 640 650
AETQLQAALL KNAWLAEENG RLQAKTDWVR KVEAENSEVR GHLGRACQER
660 670 680 690 700
DASGLIAEQL LQQAARGQDR QQQLQRDPQK ALCDLHPSWK EIQALQCRPG
710 720 730 740 750
HPPEQPWETS QMPESQVKGS RRPKFHARPE DYAVSQPNRD IQEKREASLE
760 770 780 790 800
ESPVALGESA SVPQVSETVP ASQPLSKKTS SQSNSSSEGS MWATVPSSPT
810 820 830 840 850
LDRDTASEVD DLEPDSVSLA LEMGGSAAPA APKLKIFMAQ YNYNPFEGPN
860 870 880 890 900
DHPEGELPLT AGDYIYIFGD MDEDGFYEGE LEDGRRGLVP SNFVEQIPDS
910 920 930 940 950
YIPGCLPAKS PDLGPSQLPA GQDEALEEDS LLSGKAQGVV DRGLCQMVRV
960 970 980 990 1000
GSKTEVATEI LDTKTEACQL GLLQSMGKQG LSRPLLGTKG VLRMAPMQLH
1010 1020 1030 1040 1050
LQNVTATSAN ITWVYSSHRH PHVVYLDDRE HALTPAGVSC YTFQGLCPGT
1060 1070 1080 1090 1100
HYRARVEVRL PRDLLQVYWG TMSSTVTFDT LLAGPPYPPL DVLVERHASP
1110 1120 1130 1140 1150
GVLVVSWLPV TIDSAGSSNG VQVTGYAVYA DGLKVCEVAD ATAGSTLLEF
1160 1170 1180 1190 1200
SQLQVPLTWQ KVSVRTMSLC GESLDSVPAQ IPEDFFMCHR WPETPPFSYT
1210 1220 1230 1240 1250
CGDPSTYRVT FPVCPQKLSL APPSAKASPH NPGSCGEPQA KFLEAFFEEP
1260 1270 1280 1290 1300
PRRQSPVSNL GSEGECPSSG AGSQAQELAE AWEGCRKDLL FQKSPQNHRP
1310 1320 1330 1340 1350
PSVSDQPGEK ENCSQHMGTS KSPAPGFIHL RTECGPRKEP CQEKAALERV
1360 1370 1380 1390 1400
LRQKQDAQGF TPPQLGASQQ YASDFHNVLK EEQEALCLDL WGTERREERR
1410 1420 1430 1440 1450
EPEPHSRQGQ ALGVKRGCQL HEPSSALCPA PSAKVIKMPR GGPQQLGTGA
1460 1470 1480 1490 1500
NTPARVFVAL SDYNPLVMSA NLKAAEEELV FQKRQLLRVW GSQDTHDFYL
1510 1520 1530 1540 1550
SECNRQVGNI PGRLVAEMEV GTEQTDRRWR SPAQGNLPSV AHLEDFQGLT
1560 1570 1580 1590 1600
IPQGSSLVLQ GNSKRLPLWT PKIMIAALDY DPGDGQMGGQ GKGRLALRAG
1610 1620 1630
DVVMVYGPMD DQGFYYGELG GHRGLVPAHL LDHMSLHGH
Length:1,639
Mass (Da):180,717
Last modified:March 21, 2012 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1A465ECFDBE7903
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH35246 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB33336 differs from that shown. Reason: Frameshift at position 652.Curated
The sequence CAB61362 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti396A → E in BAB33336 (PubMed:11258795).Curated1
Sequence conflicti437K → E in BAB33336 (PubMed:11258795).Curated1
Sequence conflicti653S → P in BAB33336 (PubMed:11258795).Curated1
Sequence conflicti882E → D in BAB33336 (PubMed:11258795).Curated1
Sequence conflicti1307P → T in AAH35246 (PubMed:15489334).Curated1
Sequence conflicti1314S → Y in CAB61362 (PubMed:17974005).Curated1
Sequence conflicti1314S → Y in AAH35246 (PubMed:15489334).Curated1
Sequence conflicti1391W → R in AAH35246 (PubMed:15489334).Curated1
Sequence conflicti1484R → K in BAB33336 (PubMed:11258795).Curated1
Sequence conflicti1536N → H in BAB33336 (PubMed:11258795).Curated1
Sequence conflicti1536N → H in CAB55970 (PubMed:17974005).Curated1
Sequence conflicti1536N → H in AAH35246 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0289691513R → C2 PublicationsCorresponds to variant dbSNP:rs374395444Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC023490 Genomic DNA No translation available.
AB051453 mRNA Translation: BAB33336.1 Frameshift.
AL117509 mRNA Translation: CAB55970.1
AL133030 mRNA Translation: CAB61362.2 Different initiation.
BC035246 mRNA Translation: AAH35246.2 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46665.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T17280
T42704

NCBI Reference Sequences

More...
RefSeqi
NP_056487.1, NM_015672.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000619918; ENSP00000483386; ENSG00000275793

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
85376

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:85376

UCSC genome browser

More...
UCSCi
uc002zsd.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC023490 Genomic DNA No translation available.
AB051453 mRNA Translation: BAB33336.1 Frameshift.
AL117509 mRNA Translation: CAB55970.1
AL133030 mRNA Translation: CAB61362.2 Different initiation.
BC035246 mRNA Translation: AAH35246.2 Different initiation.
CCDSiCCDS46665.1
PIRiT17280
T42704
RefSeqiNP_056487.1, NM_015672.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2EGENMR-A1572-1639[»]
SMRiQ9UFD9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi124503, 22 interactors
CORUMiQ9UFD9
IntActiQ9UFD9, 32 interactors
STRINGi9606.ENSP00000483386

PTM databases

iPTMnetiQ9UFD9
PhosphoSitePlusiQ9UFD9

Polymorphism and mutation databases

BioMutaiRIMBP3
DMDMi380865484

Proteomic databases

jPOSTiQ9UFD9
MaxQBiQ9UFD9
PaxDbiQ9UFD9
PeptideAtlasiQ9UFD9
PRIDEiQ9UFD9
ProteomicsDBi84178

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000619918; ENSP00000483386; ENSG00000275793
GeneIDi85376
KEGGihsa:85376
UCSCiuc002zsd.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
85376

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RIMBP3

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0016277
HIX0041402
HIX0197170
HGNCiHGNC:29344 RIMBP3
HPAiHPA001183
MIMi612699 gene
neXtProtiNX_Q9UFD9
OpenTargetsiENSG00000275793

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3632 Eukaryota
ENOG410XZ8W LUCA
GeneTreeiENSGT00950000183203
HOGENOMiHOG000090231
InParanoidiQ9UFD9
OMAiAQIPEDC
OrthoDBi102427at2759
PhylomeDBiQ9UFD9
TreeFamiTF316230

Miscellaneous databases

EvolutionaryTraceiQ9UFD9

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
85376

Protein Ontology

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PROi
PR:Q9UFD9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000275793 Expressed in 32 organ(s), highest expression level in testis
GenevisibleiQ9UFD9 HS

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR040325 RIMBP1/2/3
IPR035515 Rimbp3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR14234 PTHR14234, 1 hit
PTHR14234:SF21 PTHR14234:SF21, 1 hit
PfamiView protein in Pfam
PF07653 SH3_2, 1 hit
PF14604 SH3_9, 1 hit
SMARTiView protein in SMART
SM00326 SH3, 3 hits
SUPFAMiSSF49265 SSF49265, 1 hit
SSF50044 SSF50044, 3 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 2 hits
PS50002 SH3, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRIM3A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UFD9
Secondary accession number(s): Q8IYP7, Q9BY94, Q9UFQ5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 21, 2012
Last modified: July 3, 2019
This is version 143 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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