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Entry version 155 (16 Oct 2019)
Sequence version 3 (16 Apr 2014)
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Protein

Zinc finger and BTB domain-containing protein 47

Gene

ZBTB47

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri436 – 459C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri463 – 485C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri490 – 513C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri520 – 542C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri548 – 570C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri576 – 598C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri604 – 626C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri632 – 654C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri660 – 687C2H2-type 9PROSITE-ProRule annotationAdd BLAST28

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q9UFB7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 47
Alternative name(s):
Zinc finger protein 651
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZBTB47
Synonyms:KIAA1190, ZNF651
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26955 ZBTB47

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UFB7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000114853

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162409466

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UFB7

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZBTB47

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74761930

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002518961 – 747Zinc finger and BTB domain-containing protein 47Add BLAST747

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki190Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UFB7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UFB7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UFB7

PeptideAtlas

More...
PeptideAtlasi
Q9UFB7

PRoteomics IDEntifications database

More...
PRIDEi
Q9UFB7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
43241
84176 [Q9UFB7-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UFB7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UFB7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000114853 Expressed in 190 organ(s), highest expression level in heart left ventricle

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UFB7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UFB7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA074057

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124993, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UFB7, 13 interactors

Molecular INTeraction database

More...
MINTi
Q9UFB7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000232974

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UFB7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini15 – 83BTBPROSITE-ProRule annotationAdd BLAST69

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi191 – 354Glu-richAdd BLAST164
Compositional biasi695 – 739Pro-richAdd BLAST45

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri436 – 459C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri463 – 485C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri490 – 513C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri520 – 542C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri548 – 570C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri576 – 598C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri604 – 626C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri632 – 654C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri660 – 687C2H2-type 9PROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160089

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000155764

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UFB7

KEGG Orthology (KO)

More...
KOi
K10518

Identification of Orthologs from Complete Genome Data

More...
OMAi
PHPKIYA

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UFB7

TreeFam database of animal gene trees

More...
TreeFami
TF332655

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 7 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UFB7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGRLNEQRLF QPDLCDVDLV LVPQRSVFPA HKGVLAAYSQ FFHSLFTQNK
60 70 80 90 100
QLQRVELSLE ALAPGGLQQI LNFIYTSKLL VNAANVHEVL SAASLLQMAD
110 120 130 140 150
IAASCQELLD ARSLGPPGPG TVALAQPAAS CTPAAPPYYC DIKQEADTPG
160 170 180 190 200
LPKIYAREGP DPYSVRVEDG AGTAGGTVPA TIGPAQPFFK EEKEGGVEEA
210 220 230 240 250
GGPPASLCKL EGGEELEEEL GGSGTYSRRE QSQIIVEVNL NNQTLHVSTG
260 270 280 290 300
PEGKPGAGPS PATVVLGRED GLQRHSDEEE EDDEEEEEEE EEEEGGGSGR
310 320 330 340 350
EEEEEEEGGS QGEEEEEEED GHSEQEEEEE EEEEEGPSEQ DQESSEEEEG
360 370 380 390 400
EEGEAGGKQG PRGSRSSRAD PPPHSHMATR SRENARRRGT PEPEEAGRRG
410 420 430 440 450
GKRPKPPPGV ASASARGPPA TDGLGAKVKL EEKQHHPCQK CPRVFNNRWY
460 470 480 490 500
LEKHMNVTHS RMQICDQCGK RFLLESELLL HRQTDCERNI QCVTCGKAFK
510 520 530 540 550
KLWSLHEHNK IVHGYAEKKF SCEICEKKFY TMAHVRKHMV AHTKDMPFTC
560 570 580 590 600
ETCGKSFKRS MSLKVHSLQH SGEKPFRCEN CNERFQYKYQ LRSHMSIHIG
610 620 630 640 650
HKQFMCQWCG KDFNMKQYFD EHMKTHTGEK PYICEICGKS FTSRPNMKRH
660 670 680 690 700
RRTHTGEKPY PCDVCGQRFR FSNMLKAHKE KCFRVSHTLA GDGVPAAPGL
710 720 730 740
PPTQPQAHAL PLLPGLPQTL PPPPHLPPPP PLFPTTASPG GRMNANN
Length:747
Mass (Da):82,760
Last modified:April 16, 2014 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8F816B6B7BD4DFDE
GO
Isoform 2 (identifier: Q9UFB7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     330-430: Missing.

Note: No experimental confirmation available.
Show »
Length:646
Mass (Da):72,115
Checksum:iD4EA35455F89ED13
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RDG5D6RDG5_HUMAN
Zinc finger and BTB domain-containi...
ZBTB47
293Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH21855 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence CAB61386 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti160P → R in BAC86810 (PubMed:14702039).Curated1
Sequence conflicti272L → P in BAC86810 (PubMed:14702039).Curated1
Sequence conflicti282D → G in BAC86810 (PubMed:14702039).Curated1
Sequence conflicti301Missing in BAC86810 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027715385A → T. Corresponds to variant dbSNP:rs9878239Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_054051330 – 430Missing in isoform 2. 1 PublicationAdd BLAST101

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK127065 mRNA Translation: BAC86810.1
AC006059 Genomic DNA No translation available.
AL133062 mRNA Translation: CAB61386.2 Different initiation.
BC021855 mRNA Translation: AAH21855.1 Different initiation.
AB033016 mRNA Translation: BAA86504.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46805.2 [Q9UFB7-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
T42663

NCBI Reference Sequences

More...
RefSeqi
NP_660149.2, NM_145166.3 [Q9UFB7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000232974; ENSP00000232974; ENSG00000114853 [Q9UFB7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
92999

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:92999

UCSC genome browser

More...
UCSCi
uc003clu.3 human [Q9UFB7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127065 mRNA Translation: BAC86810.1
AC006059 Genomic DNA No translation available.
AL133062 mRNA Translation: CAB61386.2 Different initiation.
BC021855 mRNA Translation: AAH21855.1 Different initiation.
AB033016 mRNA Translation: BAA86504.1
CCDSiCCDS46805.2 [Q9UFB7-1]
PIRiT42663
RefSeqiNP_660149.2, NM_145166.3 [Q9UFB7-1]

3D structure databases

SMRiQ9UFB7
ModBaseiSearch...

Protein-protein interaction databases

BioGridi124993, 4 interactors
IntActiQ9UFB7, 13 interactors
MINTiQ9UFB7
STRINGi9606.ENSP00000232974

PTM databases

iPTMnetiQ9UFB7
PhosphoSitePlusiQ9UFB7

Polymorphism and mutation databases

BioMutaiZBTB47
DMDMi74761930

Proteomic databases

jPOSTiQ9UFB7
MassIVEiQ9UFB7
PaxDbiQ9UFB7
PeptideAtlasiQ9UFB7
PRIDEiQ9UFB7
ProteomicsDBi43241
84176 [Q9UFB7-1]

Genome annotation databases

EnsembliENST00000232974; ENSP00000232974; ENSG00000114853 [Q9UFB7-1]
GeneIDi92999
KEGGihsa:92999
UCSCiuc003clu.3 human [Q9UFB7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92999

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZBTB47
HGNCiHGNC:26955 ZBTB47
HPAiHPA074057
neXtProtiNX_Q9UFB7
OpenTargetsiENSG00000114853
PharmGKBiPA162409466

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000160089
HOGENOMiHOG000155764
InParanoidiQ9UFB7
KOiK10518
OMAiPHPKIYA
OrthoDBi1318335at2759
PhylomeDBiQ9UFB7
TreeFamiTF332655

Enzyme and pathway databases

SIGNORiQ9UFB7

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZBTB47 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
92999
PharosiQ9UFB7

Protein Ontology

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PROi
PR:Q9UFB7

Gene expression databases

BgeeiENSG00000114853 Expressed in 190 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiQ9UFB7 baseline and differential
GenevisibleiQ9UFB7 HS

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 9 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 7 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZBT47_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UFB7
Secondary accession number(s): H7BXD3
, Q6ZSY6, Q8WTY8, Q9ULN0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: April 16, 2014
Last modified: October 16, 2019
This is version 155 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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