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UniProtKB - Q9UEU7 (Q9UEU7_HUMAN)
Protein
Amine oxidase
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
Cofactori
L-topaquinoneUniRule annotation, Cu cationUniRule annotationNote: Contains 1 topaquinone per subunit.UniRule annotation
GO - Molecular functioni
- copper ion binding Source: InterPro
- primary amine oxidase activity Source: InterPro
- quinone binding Source: InterPro
GO - Biological processi
- amine metabolic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | OxidoreductaseUniRule annotation |
Ligand | CopperUniRule annotation, Metal-bindingUniRule annotation |
Names & Taxonomyi
Protein namesi | |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
PTM / Processingi
Post-translational modificationi
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.UniRule annotation
Keywords - PTMi
TPQUniRule annotationProteomic databases
PeptideAtlasi | Q9UEU7 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the copper/topaquinone oxidase family.UniRule annotation
Phylogenomic databases
OrthoDBi | 1320015at2759 |
Family and domain databases
Gene3Di | 2.70.98.20, 1 hit |
InterProi | View protein in InterPro IPR000269, Cu_amine_oxidase IPR036460, Cu_amine_oxidase_C_sf |
PANTHERi | PTHR10638, PTHR10638, 1 hit |
SUPFAMi | SSF49998, SSF49998, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q9UEU7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GVGFFLRPYN FFDEDPSFYS ADSIYFRGDQ DAGACEVNPL ACLPQAAACA
60
PDLPAFSHGG FSHN
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF054985 mRNA Translation: AAC09346.1 |
RefSeqi | NP_001264660.1, NM_001277731.1 NP_001264661.1, NM_001277732.1 NP_003725.1, NM_003734.3 |
Genome annotation databases
GeneIDi | 8639 |
KEGGi | hsa:8639 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF054985 mRNA Translation: AAC09346.1 |
RefSeqi | NP_001264660.1, NM_001277731.1 NP_001264661.1, NM_001277732.1 NP_003725.1, NM_003734.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q9UEU7 |
Protocols and materials databases
DNASUi | 8639 |
Genome annotation databases
GeneIDi | 8639 |
KEGGi | hsa:8639 |
Organism-specific databases
CTDi | 8639 |
Phylogenomic databases
OrthoDBi | 1320015at2759 |
Miscellaneous databases
BioGRID-ORCSi | 8639, 11 hits in 1063 CRISPR screens |
GenomeRNAii | 8639 |
Family and domain databases
Gene3Di | 2.70.98.20, 1 hit |
InterProi | View protein in InterPro IPR000269, Cu_amine_oxidase IPR036460, Cu_amine_oxidase_C_sf |
PANTHERi | PTHR10638, PTHR10638, 1 hit |
SUPFAMi | SSF49998, SSF49998, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9UEU7_HUMAN | |
Accessioni | Q9UEU7Primary (citable) accession number: Q9UEU7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | May 1, 2000 | |
Last modified: | May 25, 2022 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |