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Entry version 186 (11 Dec 2019)
Sequence version 3 (19 Jul 2004)
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Protein

Tripartite motif-containing protein 10

Gene

TRIM10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Seems to play an important role in erythropoiesis.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri16 – 61RING-typePROSITE-ProRule annotationAdd BLAST46
Zinc fingeri94 – 135B box-typePROSITE-ProRule annotationAdd BLAST42

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-877300 Interferon gamma signaling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tripartite motif-containing protein 10
Alternative name(s):
B30-RING finger protein
RING finger protein 9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TRIM10
Synonyms:RFB30, RNF9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000204613.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10072 TRIM10

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605701 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UDY6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10107

Open Targets

More...
OpenTargetsi
ENSG00000204613

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA35536

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UDY6 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TRIM10

Domain mapping of disease mutations (DMDM)

More...
DMDMi
50403805

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000562111 – 481Tripartite motif-containing protein 10Add BLAST481

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UDY6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UDY6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UDY6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UDY6

PeptideAtlas

More...
PeptideAtlasi
Q9UDY6

PRoteomics IDEntifications database

More...
PRIDEi
Q9UDY6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
84134 [Q9UDY6-1]
84135 [Q9UDY6-2]

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UDY6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000204613 Expressed in 54 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UDY6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UDY6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043325

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115413, 26 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UDY6, 24 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000397073

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9UDY6 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UDY6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini292 – 481B30.2/SPRYPROSITE-ProRule annotationAdd BLAST190

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili150 – 177Sequence analysisAdd BLAST28

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRIM/RBCC family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri16 – 61RING-typePROSITE-ProRule annotationAdd BLAST46
Zinc fingeri94 – 135B box-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2177 Eukaryota
ENOG4111G04 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161525

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234133

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UDY6

KEGG Orthology (KO)

More...
KOi
K12002

Identification of Orthologs from Complete Genome Data

More...
OMAi
GGSCTMG

Database of Orthologous Groups

More...
OrthoDBi
1334551at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UDY6

TreeFam database of animal gene trees

More...
TreeFami
TF342569

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00021 BBOX, 1 hit
cd16593 RING-HC_TRIM10_C-IV, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR006574 PRY
IPR003877 SPRY_dom
IPR042784 TRIM10_RING-HC
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13765 PRY, 1 hit
PF00622 SPRY, 1 hit
PF00643 zf-B_box, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01407 BUTYPHLNCDUF

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00336 BBOX, 1 hit
SM00589 PRY, 1 hit
SM00184 RING, 1 hit
SM00449 SPRY, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform Alpha (identifier: Q9UDY6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MASAASVTSL ADEVNCPICQ GTLREPVTID CGHNFCRACL TRYCEIPGPD
60 70 80 90 100
LEESPTCPLC KEPFRPGSFR PNWQLANVVE NIERLQLVST LGLGEEDVCQ
110 120 130 140 150
EHGEKIYFFC EDDEMQLCVV CREAGEHATH TMRFLEDAAA PYREQIHKCL
160 170 180 190 200
KCLRKEREEI QEIQSRENKR MQVLLTQVST KRQQVISEFA HLRKFLEEQQ
210 220 230 240 250
SILLAQLESQ DGDILRQRDE FDLLVAGEIC RFSALIEELE EKNERPAREL
260 270 280 290 300
LTDIRSTLIR CETRKCRKPV AVSPELGQRI RDFPQQALPL QREMKMFLEK
310 320 330 340 350
LCFELDYEPA HISLDPQTSH PKLLLSEDHQ RAQFSYKWQN SPDNPQRFDR
360 370 380 390 400
ATCVLAHTGI TGGRHTWVVS IDLAHGGSCT VGVVSEDVQR KGELRLRPEE
410 420 430 440 450
GVWAVRLAWG FVSALGSFPT RLTLKEQPRQ VRVSLDYEVG WVTFTNAVTR
460 470 480
EPIYTFTASF TRKVIPFFGL WGRGSSFSLS S
Length:481
Mass (Da):55,037
Last modified:July 19, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49A1A11F391F5F98
GO
Isoform Beta (identifier: Q9UDY6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     369-481: VSIDLAHGGS...GRGSSFSLSS → WMARVPGDSGCCQFCSPPSVLGTEVAA

Show »
Length:395
Mass (Da):45,252
Checksum:iEDEFCB7027B6C15D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti104E → G in CAB52384 (PubMed:9271628).Curated1
Sequence conflicti104E → SR in AAG53495 (PubMed:11331580).Curated1
Sequence conflicti104E → SR in AAG53496 (PubMed:11331580).Curated1
Sequence conflicti167E → K in AAG53495 (PubMed:11331580).Curated1
Sequence conflicti167E → K in AAG53496 (PubMed:11331580).Curated1
Sequence conflicti336Y → S in CAB52384 (PubMed:9271628).Curated1
Sequence conflicti336Y → S in AAG53495 (PubMed:11331580).Curated1
Sequence conflicti377G → A in CAB52384 (PubMed:9271628).Curated1
Sequence conflicti377G → A in AAG53495 (PubMed:11331580).Curated1
Isoform Beta (identifier: Q9UDY6-2)
Sequence conflicti379C → G in AAG53496 (PubMed:11331580).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05212765R → H. Corresponds to variant dbSNP:rs12212092Ensembl.1
Natural variantiVAR_052128119V → M. Corresponds to variant dbSNP:rs17194446Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_005748369 – 481VSIDL…FSLSS → WMARVPGDSGCCQFCSPPSV LGTEVAA in isoform Beta. 2 PublicationsAdd BLAST113

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Y07829 Genomic DNA Translation: CAB52384.1
AF220122 mRNA Translation: AAG53495.1
AF220123 mRNA Translation: AAG53496.1
AB202085 Genomic DNA Translation: BAE78605.1
AB103595 Genomic DNA Translation: BAF31256.1
BA000025 Genomic DNA Translation: BAB63332.1
AB088089 Genomic DNA Translation: BAC54921.1
AL669914 Genomic DNA No translation available.
AL671859 Genomic DNA No translation available.
AL844220 Genomic DNA No translation available.
BX005441 Genomic DNA No translation available.
BX927221 Genomic DNA No translation available.
CR753815 Genomic DNA No translation available.
CR759838 Genomic DNA No translation available.
CR788282 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03268.1
CH471081 Genomic DNA Translation: EAX03269.1
BC093926 mRNA Translation: AAH93926.1
BC113419 mRNA Translation: AAI13420.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34375.1 [Q9UDY6-1]
CCDS4676.1 [Q9UDY6-2]

NCBI Reference Sequences

More...
RefSeqi
NP_006769.2, NM_006778.3 [Q9UDY6-1]
NP_439893.2, NM_052828.2 [Q9UDY6-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000259941; ENSP00000259941; ENSG00000137394 [Q9UDY6-2]
ENST00000354038; ENSP00000343695; ENSG00000137394 [Q9UDY6-1]
ENST00000376704; ENSP00000365894; ENSG00000204613 [Q9UDY6-2]
ENST00000413055; ENSP00000393787; ENSG00000227472 [Q9UDY6-2]
ENST00000416714; ENSP00000405578; ENSG00000229381 [Q9UDY6-2]
ENST00000417411; ENSP00000393576; ENSG00000237192 [Q9UDY6-2]
ENST00000426996; ENSP00000397440; ENSG00000227472 [Q9UDY6-1]
ENST00000428611; ENSP00000412370; ENSG00000229346 [Q9UDY6-2]
ENST00000431258; ENSP00000395598; ENSG00000235025 [Q9UDY6-1]
ENST00000446013; ENSP00000398404; ENSG00000237703 [Q9UDY6-2]
ENST00000447465; ENSP00000393976; ENSG00000235025 [Q9UDY6-2]
ENST00000448645; ENSP00000399446; ENSG00000229346 [Q9UDY6-1]
ENST00000449208; ENSP00000390497; ENSG00000237703 [Q9UDY6-1]
ENST00000449742; ENSP00000397073; ENSG00000204613 [Q9UDY6-1]
ENST00000451727; ENSP00000391445; ENSG00000237192 [Q9UDY6-1]
ENST00000456988; ENSP00000410849; ENSG00000229381 [Q9UDY6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10107

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10107

UCSC genome browser

More...
UCSCi
uc003npn.3 human [Q9UDY6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y07829 Genomic DNA Translation: CAB52384.1
AF220122 mRNA Translation: AAG53495.1
AF220123 mRNA Translation: AAG53496.1
AB202085 Genomic DNA Translation: BAE78605.1
AB103595 Genomic DNA Translation: BAF31256.1
BA000025 Genomic DNA Translation: BAB63332.1
AB088089 Genomic DNA Translation: BAC54921.1
AL669914 Genomic DNA No translation available.
AL671859 Genomic DNA No translation available.
AL844220 Genomic DNA No translation available.
BX005441 Genomic DNA No translation available.
BX927221 Genomic DNA No translation available.
CR753815 Genomic DNA No translation available.
CR759838 Genomic DNA No translation available.
CR788282 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03268.1
CH471081 Genomic DNA Translation: EAX03269.1
BC093926 mRNA Translation: AAH93926.1
BC113419 mRNA Translation: AAI13420.1
CCDSiCCDS34375.1 [Q9UDY6-1]
CCDS4676.1 [Q9UDY6-2]
RefSeqiNP_006769.2, NM_006778.3 [Q9UDY6-1]
NP_439893.2, NM_052828.2 [Q9UDY6-2]

3D structure databases

SMRiQ9UDY6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi115413, 26 interactors
IntActiQ9UDY6, 24 interactors
STRINGi9606.ENSP00000397073

PTM databases

PhosphoSitePlusiQ9UDY6

Polymorphism and mutation databases

BioMutaiTRIM10
DMDMi50403805

Proteomic databases

EPDiQ9UDY6
jPOSTiQ9UDY6
MassIVEiQ9UDY6
PaxDbiQ9UDY6
PeptideAtlasiQ9UDY6
PRIDEiQ9UDY6
ProteomicsDBi84134 [Q9UDY6-1]
84135 [Q9UDY6-2]

Genome annotation databases

EnsembliENST00000259941; ENSP00000259941; ENSG00000137394 [Q9UDY6-2]
ENST00000354038; ENSP00000343695; ENSG00000137394 [Q9UDY6-1]
ENST00000376704; ENSP00000365894; ENSG00000204613 [Q9UDY6-2]
ENST00000413055; ENSP00000393787; ENSG00000227472 [Q9UDY6-2]
ENST00000416714; ENSP00000405578; ENSG00000229381 [Q9UDY6-2]
ENST00000417411; ENSP00000393576; ENSG00000237192 [Q9UDY6-2]
ENST00000426996; ENSP00000397440; ENSG00000227472 [Q9UDY6-1]
ENST00000428611; ENSP00000412370; ENSG00000229346 [Q9UDY6-2]
ENST00000431258; ENSP00000395598; ENSG00000235025 [Q9UDY6-1]
ENST00000446013; ENSP00000398404; ENSG00000237703 [Q9UDY6-2]
ENST00000447465; ENSP00000393976; ENSG00000235025 [Q9UDY6-2]
ENST00000448645; ENSP00000399446; ENSG00000229346 [Q9UDY6-1]
ENST00000449208; ENSP00000390497; ENSG00000237703 [Q9UDY6-1]
ENST00000449742; ENSP00000397073; ENSG00000204613 [Q9UDY6-1]
ENST00000451727; ENSP00000391445; ENSG00000237192 [Q9UDY6-1]
ENST00000456988; ENSP00000410849; ENSG00000229381 [Q9UDY6-1]
GeneIDi10107
KEGGihsa:10107
UCSCiuc003npn.3 human [Q9UDY6-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
10107
DisGeNETi10107
EuPathDBiHostDB:ENSG00000204613.10

GeneCards: human genes, protein and diseases

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GeneCardsi
TRIM10
HGNCiHGNC:10072 TRIM10
HPAiHPA043325
MIMi605701 gene
neXtProtiNX_Q9UDY6
OpenTargetsiENSG00000204613
PharmGKBiPA35536

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG4111G04 LUCA
GeneTreeiENSGT00940000161525
HOGENOMiHOG000234133
InParanoidiQ9UDY6
KOiK12002
OMAiGGSCTMG
OrthoDBi1334551at2759
PhylomeDBiQ9UDY6
TreeFamiTF342569

Enzyme and pathway databases

ReactomeiR-HSA-877300 Interferon gamma signaling

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
TRIM10 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
10107
PharosiQ9UDY6 Tdark

Protein Ontology

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PROi
PR:Q9UDY6
RNActiQ9UDY6 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000204613 Expressed in 54 organ(s), highest expression level in liver
ExpressionAtlasiQ9UDY6 baseline and differential
GenevisibleiQ9UDY6 HS

Family and domain databases

CDDicd00021 BBOX, 1 hit
cd16593 RING-HC_TRIM10_C-IV, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR006574 PRY
IPR003877 SPRY_dom
IPR042784 TRIM10_RING-HC
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF13765 PRY, 1 hit
PF00622 SPRY, 1 hit
PF00643 zf-B_box, 1 hit
PRINTSiPR01407 BUTYPHLNCDUF
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00589 PRY, 1 hit
SM00184 RING, 1 hit
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTRI10_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UDY6
Secondary accession number(s): A6NF84
, Q5SRJ5, Q5SRK8, Q86Z08, Q96QB6, Q9C023, Q9C024
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: July 19, 2004
Last modified: December 11, 2019
This is version 186 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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