Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc finger matrin-type protein 5

Gene

ZMAT5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri51 – 79C3H1-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

  • mRNA splicing, via spliceosome Source: Reactome
  • RNA splicing Source: HGNC

Keywordsi

Biological processmRNA processing, mRNA splicing
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-HSA-72165 mRNA Splicing - Minor Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger matrin-type protein 5
Alternative name(s):
U11/U12 small nuclear ribonucleoprotein 20 kDa protein
Short name:
U11/U12 snRNP 20 kDa protein
Short name:
U11/U12-20K
Gene namesi
Name:ZMAT5
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000100319.12
HGNCiHGNC:28046 ZMAT5
neXtProtiNX_Q9UDW3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus, Spliceosome

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670524

Polymorphism and mutation databases

BioMutaiZMAT5
DMDMi74753269

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002541141 – 170Zinc finger matrin-type protein 5Add BLAST170

Proteomic databases

EPDiQ9UDW3
MaxQBiQ9UDW3
PaxDbiQ9UDW3
PeptideAtlasiQ9UDW3
PRIDEiQ9UDW3
ProteomicsDBi84122

PTM databases

iPTMnetiQ9UDW3
PhosphoSitePlusiQ9UDW3

Expressioni

Gene expression databases

BgeeiENSG00000100319 Expressed in 158 organ(s), highest expression level in muscle of leg
CleanExiHS_ZMAT5
ExpressionAtlasiQ9UDW3 baseline and differential
GenevisibleiQ9UDW3 HS

Organism-specific databases

HPAiHPA004858

Interactioni

Subunit structurei

Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Not found in the major spliceosome.1 Publication

Protein-protein interaction databases

BioGridi121007, 31 interactors
CORUMiQ9UDW3
IntActiQ9UDW3, 18 interactors
MINTiQ9UDW3
STRINGi9606.ENSP00000344241

Structurei

3D structure databases

ProteinModelPortaliQ9UDW3
SMRiQ9UDW3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri51 – 79C3H1-typePROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3454 Eukaryota
COG5136 LUCA
GeneTreeiENSGT00390000009869
HOGENOMiHOG000039495
HOVERGENiHBG083477
InParanoidiQ9UDW3
KOiK13152
OMAiSHMSEQD
OrthoDBiEOG091G1244
PhylomeDBiQ9UDW3
TreeFamiTF332784

Family and domain databases

InterProiView protein in InterPro
IPR013085 U1-CZ_Znf_C2H2
IPR036236 Znf_C2H2_sf
IPR000571 Znf_CCCH
IPR036855 Znf_CCCH_sf
PfamiView protein in Pfam
PF00642 zf-CCCH, 1 hit
PF06220 zf-U1, 1 hit
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF57667 SSF57667, 1 hit
SSF90229 SSF90229, 1 hit
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9UDW3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKRYFCDYC DRSFQDNLHN RKKHLNGLQH LKAKKVWYDM FRDAAAILLD
60 70 80 90 100
EQNKRPCRKF LLTGQCDFGS NCRFSHMSER DLQELSIQVE EERRAREWLL
110 120 130 140 150
DAPELPEGHL EDWLEKRAKR LSSAPSSRAE PIRTTVFQYP VGWPPVQELP
160 170
PSLRAPPPGG WPLQPRVQWG
Length:170
Mass (Da):19,971
Last modified:May 1, 2000 - v1
Checksum:iFEBF7BD946EFA5FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL160311 mRNA Translation: CAB77284.1
CR456353 mRNA Translation: CAG30239.1
CR457393 mRNA Translation: CAG33674.1
AK292671 mRNA Translation: BAF85360.1
CH471095 Genomic DNA Translation: EAW59837.1
BC009717 mRNA Translation: AAH09717.1
BK005198 mRNA Translation: DAA05496.1
CCDSiCCDS13868.1
RefSeqiNP_001003692.1, NM_001003692.1
NP_001305058.1, NM_001318129.1
NP_061976.1, NM_019103.2
UniGeneiHs.713647

Genome annotation databases

EnsembliENST00000344318; ENSP00000344241; ENSG00000100319
GeneIDi55954
KEGGihsa:55954
UCSCiuc003agn.4 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL160311 mRNA Translation: CAB77284.1
CR456353 mRNA Translation: CAG30239.1
CR457393 mRNA Translation: CAG33674.1
AK292671 mRNA Translation: BAF85360.1
CH471095 Genomic DNA Translation: EAW59837.1
BC009717 mRNA Translation: AAH09717.1
BK005198 mRNA Translation: DAA05496.1
CCDSiCCDS13868.1
RefSeqiNP_001003692.1, NM_001003692.1
NP_001305058.1, NM_001318129.1
NP_061976.1, NM_019103.2
UniGeneiHs.713647

3D structure databases

ProteinModelPortaliQ9UDW3
SMRiQ9UDW3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121007, 31 interactors
CORUMiQ9UDW3
IntActiQ9UDW3, 18 interactors
MINTiQ9UDW3
STRINGi9606.ENSP00000344241

PTM databases

iPTMnetiQ9UDW3
PhosphoSitePlusiQ9UDW3

Polymorphism and mutation databases

BioMutaiZMAT5
DMDMi74753269

Proteomic databases

EPDiQ9UDW3
MaxQBiQ9UDW3
PaxDbiQ9UDW3
PeptideAtlasiQ9UDW3
PRIDEiQ9UDW3
ProteomicsDBi84122

Protocols and materials databases

DNASUi55954
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000344318; ENSP00000344241; ENSG00000100319
GeneIDi55954
KEGGihsa:55954
UCSCiuc003agn.4 human

Organism-specific databases

CTDi55954
EuPathDBiHostDB:ENSG00000100319.12
GeneCardsiZMAT5
HGNCiHGNC:28046 ZMAT5
HPAiHPA004858
neXtProtiNX_Q9UDW3
PharmGKBiPA142670524
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3454 Eukaryota
COG5136 LUCA
GeneTreeiENSGT00390000009869
HOGENOMiHOG000039495
HOVERGENiHBG083477
InParanoidiQ9UDW3
KOiK13152
OMAiSHMSEQD
OrthoDBiEOG091G1244
PhylomeDBiQ9UDW3
TreeFamiTF332784

Enzyme and pathway databases

ReactomeiR-HSA-72165 mRNA Splicing - Minor Pathway

Miscellaneous databases

ChiTaRSiZMAT5 human
GenomeRNAii55954
PROiPR:Q9UDW3

Gene expression databases

BgeeiENSG00000100319 Expressed in 158 organ(s), highest expression level in muscle of leg
CleanExiHS_ZMAT5
ExpressionAtlasiQ9UDW3 baseline and differential
GenevisibleiQ9UDW3 HS

Family and domain databases

InterProiView protein in InterPro
IPR013085 U1-CZ_Znf_C2H2
IPR036236 Znf_C2H2_sf
IPR000571 Znf_CCCH
IPR036855 Znf_CCCH_sf
PfamiView protein in Pfam
PF00642 zf-CCCH, 1 hit
PF06220 zf-U1, 1 hit
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF57667 SSF57667, 1 hit
SSF90229 SSF90229, 1 hit
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiZMAT5_HUMAN
AccessioniPrimary (citable) accession number: Q9UDW3
Secondary accession number(s): A8K9F6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 1, 2000
Last modified: November 7, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again