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UniProtKB - Q9UBU6 (FA8A1_HUMAN)

Entry version 139 (07 Apr 2021)
Sequence version 1 (01 May 2000)
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Protein

Protein FAM8A1

Gene

FAM8A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the assembly of the HRD1 complex, a complex involved in the ubiquitin-proteasome-dependent process of ER-associated degradation (ERAD).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9UBU6

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q9UBU6

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.133.1.4, the rdd na+(li+)(k+)/h+ antiporter (rdd) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM8A1
Alternative name(s):
Autosomal highly conserved protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM8A1
Synonyms:AHCP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16372, FAM8A1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		618409, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9UBU6

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000137414.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei257 – 277HelicalSequence analysisAdd BLAST21
Transmembranei304 – 324HelicalSequence analysisAdd BLAST21
Transmembranei371 – 391HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi120 – 122WLW → ALA: Decreased interaction with SYVN1 and HERPUD1. 1 Publication3
Mutagenesisi131W → A: Decreased interaction with HERPUD1; no effect on interaction with SYVN1. 1 Publication1

Organism-specific databases

DisGeNET

More...DisGeNETi		51439

Open Targets

More...OpenTargetsi		ENSG00000137414

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA27986

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9UBU6, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		FAM8A1

Domain mapping of disease mutations (DMDM)

More...DMDMi		74753230

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000871671 – 413Protein FAM8A1Add BLAST413

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei229PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9UBU6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9UBU6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9UBU6

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9UBU6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9UBU6

PeptideAtlas

More...PeptideAtlasi		Q9UBU6

PRoteomics IDEntifications database

More...PRIDEi		Q9UBU6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		84070

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9UBU6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9UBU6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed, with a higher level of expression in testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000137414, Expressed in Brodmann (1909) area 23 and 248 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9UBU6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9UBU6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000137414, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the HRD1 complex, which comprises at least SYNV1/HRD1, FAM8A1, HERPUD1/HERP, OS9, SEL1L and UBE2J1. This interaction stabilizes FAM8A1 protein, preventing its proteasomal degradation. FAM8A1 binding to SYNV1 may promote recruitment of HERPUD1 to the HRD1 complex.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		119541, 54 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		Q9UBU6

Protein interaction database and analysis system

More...IntActi		Q9UBU6, 41 interactors

Molecular INTeraction database

More...MINTi		Q9UBU6

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000259963

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9UBU6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini242 – 408RDDAdd BLAST167

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni107 – 139Necessary and sufficient to interact with SYVN11 PublicationAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi59 – 64Poly-Ala6
Compositional biasi164 – 167Poly-Pro4

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4647, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000007346

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_053631_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9UBU6

Identification of Orthologs from Complete Genome Data

More...OMAi		GDHEPVP

Database of Orthologous Groups

More...OrthoDBi		1123503at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9UBU6

TreeFam database of animal gene trees

More...TreeFami		TF314024

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR039871, FAM8A1
IPR010432, RDD

The PANTHER Classification System

More...PANTHERi		PTHR13659, PTHR13659, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF06271, RDD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9UBU6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEGPEEARG HPPGQDDGGG DHEPVPSLRG PPTTAVPCPR DDPQAEPQAP 
        60         70         80         90        100
GRPTAPGLAA AAAADKLEPP RELRKRGEAA SGSGAELQEQ AGCEAPEAAA 
       110        120        130        140        150
PRERPARLSA REYSRQVHEW LWQSYCGYLT WHSGLAAFPA YCSPQPSPQS 
       160        170        180        190        200
FPSGGAAVPQ AAAPPPPQLG YYNPFYFLSP GAAGPDPRTA AGISTPAPVA 
       210        220        230        240        250
GLGPRAPHVQ ASVRATPVTR VGSAAPSRSP SETGRQAGRE YVIPSLAHRF 
       260        270        280        290        300
MAEMVDFFIL FFIKATIVLS IMHLSGIKDI SKFAMHYIIE EIDEDTSMED 
       310        320        330        340        350
LQKMMVVALI YRLLVCFYEI ICIWGAGGAT PGKFLLGLRV VTCDTSVLIA 
       360        370        380        390        400
PSRVLVIPSS NVSITTSTIR ALIKNFSIAS FFPAFITLLF FQHNRTAYDI 
       410 
VAGTIVVKRN GVR
Length:413
Mass (Da):44,123
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i35B92497907CCD2E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF097027 mRNA Translation: AAF07850.1
AK312814 mRNA Translation: BAG35672.1
AL138824 Genomic DNA No translation available.
AF097026 Genomic DNA Translation: AAF07849.1
CH471087 Genomic DNA Translation: EAW55382.1
BC047881 mRNA Translation: AAH47881.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4540.1

NCBI Reference Sequences

More...RefSeqi		NP_057339.1, NM_016255.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000259963; ENSP00000259963; ENSG00000137414

Database of genes from NCBI RefSeq genomes

More...GeneIDi		51439

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:51439

UCSC genome browser

More...UCSCi		uc003ncc.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF097027 mRNA Translation: AAF07850.1
AK312814 mRNA Translation: BAG35672.1
AL138824 Genomic DNA No translation available.
AF097026 Genomic DNA Translation: AAF07849.1
CH471087 Genomic DNA Translation: EAW55382.1
BC047881 mRNA Translation: AAH47881.1
CCDSiCCDS4540.1
RefSeqiNP_057339.1, NM_016255.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi119541, 54 interactors
CORUMiQ9UBU6
IntActiQ9UBU6, 41 interactors
MINTiQ9UBU6
STRINGi9606.ENSP00000259963

Protein family/group databases

TCDBi2.A.133.1.4, the rdd na+(li+)(k+)/h+ antiporter (rdd) family

PTM databases

iPTMnetiQ9UBU6
PhosphoSitePlusiQ9UBU6

Genetic variation databases

BioMutaiFAM8A1
DMDMi74753230

Proteomic databases

EPDiQ9UBU6
jPOSTiQ9UBU6
MassIVEiQ9UBU6
MaxQBiQ9UBU6
PaxDbiQ9UBU6
PeptideAtlasiQ9UBU6
PRIDEiQ9UBU6
ProteomicsDBi84070

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		68212, 100 antibodies

Genome annotation databases

EnsembliENST00000259963; ENSP00000259963; ENSG00000137414
GeneIDi51439
KEGGihsa:51439
UCSCiuc003ncc.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		51439
DisGeNETi51439

GeneCards: human genes, protein and diseases

More...GeneCardsi		FAM8A1
HGNCiHGNC:16372, FAM8A1
HPAiENSG00000137414, Low tissue specificity
MIMi618409, gene
neXtProtiNX_Q9UBU6
OpenTargetsiENSG00000137414
PharmGKBiPA27986
VEuPathDBiHostDB:ENSG00000137414.5

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4647, Eukaryota
GeneTreeiENSGT00390000007346
HOGENOMiCLU_053631_1_0_1
InParanoidiQ9UBU6
OMAiGDHEPVP
OrthoDBi1123503at2759
PhylomeDBiQ9UBU6
TreeFamiTF314024

Enzyme and pathway databases

PathwayCommonsiQ9UBU6
SIGNORiQ9UBU6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		51439, 6 hits in 999 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		51439
PharosiQ9UBU6, Tbio

Protein Ontology

More...PROi		PR:Q9UBU6
RNActiQ9UBU6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000137414, Expressed in Brodmann (1909) area 23 and 248 other tissues
ExpressionAtlasiQ9UBU6, baseline and differential
GenevisibleiQ9UBU6, HS

Family and domain databases

InterProiView protein in InterPro
IPR039871, FAM8A1
IPR010432, RDD
PANTHERiPTHR13659, PTHR13659, 1 hit
PfamiView protein in Pfam
PF06271, RDD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFA8A1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UBU6
Secondary accession number(s): B2R725
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 1, 2000
Last modified: April 7, 2021
This is version 139 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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