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Protein

SUN domain-containing ossification factor

Gene

SUCO

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processOsteogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SUN domain-containing ossification factor
Alternative name(s):
Membrane protein CH1
Protein osteopotentia homolog
SUN-like protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SUCO
Synonyms:C1orf9, CH1, OPT, SLP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000094975.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1240 SUCO

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UBS9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1011 – 1031HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
51430

Open Targets

More...
OpenTargetsi
ENSG00000094975

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25621

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SUCO

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74761893

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500006570730 – 1254SUN domain-containing ossification factorAdd BLAST1225

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi202N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi236N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi524N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi928N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi955N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1081PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

O-glycosylated. O-mannosylated by POMT1 and POMT2 and elongated by POMGNT1.1 Publication
N-glycosylated.By similarity

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9UBS9

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q9UBS9

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9UBS9

PeptideAtlas

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PeptideAtlasi
Q9UBS9

PRoteomics IDEntifications database

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PRIDEi
Q9UBS9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
84053
84054 [Q9UBS9-2]

PTM databases

GlyConnect protein glycosylation platform

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GlyConnecti
1775

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q9UBS9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UBS9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in pancreas and testis and to a lower extent in prostate, ovary, heart, thymus, small intestine and spleen.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000094975 Expressed in 235 organ(s), highest expression level in caput epididymis

CleanEx database of gene expression profiles

More...
CleanExi
HS_C1orf9

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9UBS9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UBS9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA047251

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
119536, 24 interactors

Protein interaction database and analysis system

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IntActi
Q9UBS9, 21 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000263688

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9UBS9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UBS9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini284 – 453SUNPROSITE-ProRule annotationAdd BLAST170

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili909 – 1009Sequence analysisAdd BLAST101

Keywords - Domaini

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1396 Eukaryota
ENOG41116S0 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00390000013502

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000070169

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG107549

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9UBS9

Identification of Orthologs from Complete Genome Data

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OMAi
LHATKKV

Database of Orthologous Groups

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OrthoDBi
890782at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UBS9

TreeFam database of animal gene trees

More...
TreeFami
TF105817

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR012919 SUN_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07738 Sad1_UNC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785 SSF49785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51469 SUN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UBS9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKKHRRALAL VSCLFLCSLV WLPSWRVCCK ESSSASASSY YSQDDNCALE
60 70 80 90 100
NEDVQFQKKD EREGPINAES LGKSGSNLPI SPKEHKLKDD SIVDVQNTES
110 120 130 140 150
KKLSPPVVET LPTVDLHEES SNAVVDSETV ENISSSSTSE ITPISKLDEI
160 170 180 190 200
EKSGTIPIAK PSETEQSETD CDVGEALDAS APIEQPSFVS PPDSLVGQHI
210 220 230 240 250
ENVSSSHGKG KITKSEFESK VSASEQGGGD PKSALNASDN LKNESSDYTK
260 270 280 290 300
PGDIDPTSVA SPKDPEDIPT FDEWKKKVME VEKEKSQSMH ASSNGGSHAT
310 320 330 340 350
KKVQKNRNNY ASVECGAKIL AANPEAKSTS AILIENMDLY MLNPCSTKIW
360 370 380 390 400
FVIELCEPIQ VKQLDIANYE LFSSTPKDFL VSISDRYPTN KWIKLGTFHG
410 420 430 440 450
RDERNVQSFP LDEQMYAKYV KMFIKYIKVE LLSHFGSEHF CPLSLIRVFG
460 470 480 490 500
TSMVEEYEEI ADSQYHSERQ ELFDEDYDYP LDYNTGEDKS SKNLLGSATN
510 520 530 540 550
AILNMVNIAA NILGAKTEDL TEGNKSISEN ATATAAPKMP ESTPVSTPVP
560 570 580 590 600
SPEYVTTEVH THDMEPSTPD TPKESPIVQL VQEEEEEASP STVTLLGSGE
610 620 630 640 650
QEDESSPWFE SETQIFCSEL TTICCISSFS EYIYKWCSVR VALYRQRSRT
660 670 680 690 700
ALSKGKDYLV LAQPPLLLPA ESVDVSVLQP LSGELENTNI EREAETVVLG
710 720 730 740 750
DLSSSMHQDD LVNHTVDAVE LEPSHSQTLS QSLLLDITPE INPLPKIEVS
760 770 780 790 800
ESVEYEAGHI PSPVIPQESS VEIDNETEQK SESFSSIEKP SITYETNKVN
810 820 830 840 850
ELMDNIIKED VNSMQIFTKL SETIVPPINT ATVPDNEDGE AKMNIADTAK
860 870 880 890 900
QTLISVVDSS SLPEVKEEEQ SPEDALLRGL QRTATDFYAE LQNSTDLGYA
910 920 930 940 950
NGNLVHGSNQ KESVFMRLNN RIKALEVNMS LSGRYLEELS QRYRKQMEEM
960 970 980 990 1000
QKAFNKTIVK LQNTSRIAEE QDQRQTEAIQ LLQAQLTNMT QLVSNLSATV
1010 1020 1030 1040 1050
AELKREVSDR QSYLVISLVL CVVLGLMLCM QRCRNTSQFD GDYISKLPKS
1060 1070 1080 1090 1100
NQYPSPKRCF SSYDDMNLKR RTSFPLMRSK SLQLTGKEVD PNDLYIVEPL
1110 1120 1130 1140 1150
KFSPEKKKKR CKYKIEKIET IKPEEPLHPI ANGDIKGRKP FTNQRDFSNM
1160 1170 1180 1190 1200
GEVYHSSYKG PPSEGSSETS SQSEESYFCG ISACTSLCNG QSQKTKTEKR
1210 1220 1230 1240 1250
ALKRRRSKVQ DQGKLIKTLI QTKSGSLPSL HDIIKGNKEI TVGTFGVTAV

SGHI
Length:1,254
Mass (Da):139,430
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4EBA1ABCC27DAAB1
GO
Isoform 2 (identifier: Q9UBS9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MRGFLARPFL...SGRGKKEEKM
     60-96: Missing.
     421-427: Missing.

Note: No experimental confirmation available.
Show »
Length:1,405
Mass (Da):156,418
Checksum:iFA5EB6BA78F4A6DD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DYM4B4DYM4_HUMAN
SUN domain-containing ossification ...
SUCO
883Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WV04A0A087WV04_HUMAN
SUN domain-containing ossification ...
SUCO
691Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti452S → N in AAF04619 (Ref. 2) Curated1
Sequence conflicti811V → M in AAF04619 (Ref. 2) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0279211M → MRGFLARPFLSTNQHLAQWG SPLPQGKGLVQLPSQHTRHS RPFHELCSKEENSATVPKLI SLVVSSETIDFSNKTMDSRR DWEREKRILEGKLQLPKALA RTQRARDEGRAWTSRWLQRR RSPESCEAPLSAPLWGPQRG LPGREPLRSRSASAIALRTI GHILALLLRLLHLGLGSGGC REDVPPSGRGKKEEKM in isoform 2. 1 Publication1
Alternative sequenceiVSP_02792260 – 96Missing in isoform 2. 1 PublicationAdd BLAST37
Alternative sequenceiVSP_027923421 – 427Missing in isoform 2. 1 Publication7

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ250075 mRNA Translation: CAB57360.1
AF097535 mRNA Translation: AAF04619.1
AL035291 mRNA Translation: CAA22894.1
Z96050 Genomic DNA No translation available.
Z94054 Genomic DNA No translation available.
BC137125 mRNA Translation: AAI37126.1
CH471067 Genomic DNA Translation: EAW90931.1
AF310265 Genomic DNA Translation: AAK28742.1
AF310266 Genomic DNA Translation: AAK28743.1
AF310267 Genomic DNA Translation: AAK28744.1
AF310268 Genomic DNA Translation: AAK28745.1
AF310269 Genomic DNA Translation: AAK28746.1
AF310270 Genomic DNA Translation: AAK28747.1
AF310271 Genomic DNA Translation: AAK28748.1
AF310272 Genomic DNA Translation: AAK28749.1
AF310273 Genomic DNA Translation: AAK28750.1
AF310274 Genomic DNA Translation: AAK28751.1
AF310275 Genomic DNA Translation: AAK28752.1
AF310276 Genomic DNA Translation: AAK28753.1
AF310277 Genomic DNA Translation: AAK28754.1
AF310278 Genomic DNA Translation: AAK28755.1
AF310279 Genomic DNA Translation: AAK28756.1
AF310280 Genomic DNA Translation: AAK28757.1
AF310281 Genomic DNA Translation: AAK28758.1
AF310282 Genomic DNA Translation: AAK28759.1
AF310283 Genomic DNA Translation: AAK28760.1
AF310284 Genomic DNA Translation: AAK28761.1
AF310285 Genomic DNA Translation: AAK28762.1
AF310286 Genomic DNA Translation: AAK28763.1
AF310287 Genomic DNA Translation: AAK28764.1
AF310288 Genomic DNA Translation: AAK28765.1
AF310289 Genomic DNA Translation: AAK28766.1
AF310290 Genomic DNA Translation: AAK28767.1
AF310291 Genomic DNA Translation: AAK28768.1
AF310292 Genomic DNA Translation: AAK28769.1
AF310293 Genomic DNA Translation: AAK28770.1
AF310294 Genomic DNA Translation: AAK28771.1
AF310295 Genomic DNA Translation: AAK28772.1
AF310296 Genomic DNA Translation: AAK28773.1
AF310297 Genomic DNA Translation: AAK28774.1
AF310298 Genomic DNA Translation: AAK28775.1
AF310299 Genomic DNA Translation: AAK28776.1
AF310300 Genomic DNA Translation: AAK28777.1
AF310301 Genomic DNA Translation: AAK28778.1
AF310302 Genomic DNA Translation: AAK28779.1
AF310303 Genomic DNA Translation: AAK28780.1
AF310304 Genomic DNA Translation: AAK28781.1
AF310305 Genomic DNA Translation: AAK28782.1
AF310306 Genomic DNA Translation: AAK28783.1
AF310307 Genomic DNA Translation: AAK28784.1
AF310308 Genomic DNA Translation: AAK28785.1
AF310309 Genomic DNA Translation: AAK28786.1
AF310310 Genomic DNA Translation: AAK28787.1
AF310311 Genomic DNA Translation: AAK28788.1
AF310312 Genomic DNA Translation: AAK28789.1
AF310313 Genomic DNA Translation: AAK28790.1
AF310314 Genomic DNA Translation: AAK28791.1
AF310315 Genomic DNA Translation: AAK28792.1
AF310316 Genomic DNA Translation: AAK28793.1
AF310317 Genomic DNA Translation: AAK28794.1
AF310318 Genomic DNA Translation: AAK28795.1
AF310319 Genomic DNA Translation: AAK28796.1
AF310320 Genomic DNA Translation: AAK28797.1
AF310321 Genomic DNA Translation: AAK28798.1
AF310322 Genomic DNA Translation: AAK28799.1
AF310323 Genomic DNA Translation: AAK28800.1
AF310324 Genomic DNA Translation: AAK28801.1
AF310325 Genomic DNA Translation: AAK28802.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS1303.1 [Q9UBS9-1]
CCDS65726.1 [Q9UBS9-2]

Protein sequence database of the Protein Information Resource

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PIRi
JC7185

NCBI Reference Sequences

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RefSeqi
NP_001269679.1, NM_001282750.1
NP_001269680.1, NM_001282751.1
NP_055098.1, NM_014283.4 [Q9UBS9-1]
NP_057311.3, NM_016227.3 [Q9UBS9-2]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.204559

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENST00000263688; ENSP00000263688; ENSG00000094975 [Q9UBS9-1]
ENST00000367723; ENSP00000356696; ENSG00000094975 [Q9UBS9-2]
ENST00000608151; ENSP00000477484; ENSG00000094975 [Q9UBS9-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
51430

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:51430

UCSC genome browser

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UCSCi
uc001giq.6 human [Q9UBS9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250075 mRNA Translation: CAB57360.1
AF097535 mRNA Translation: AAF04619.1
AL035291 mRNA Translation: CAA22894.1
Z96050 Genomic DNA No translation available.
Z94054 Genomic DNA No translation available.
BC137125 mRNA Translation: AAI37126.1
CH471067 Genomic DNA Translation: EAW90931.1
AF310265 Genomic DNA Translation: AAK28742.1
AF310266 Genomic DNA Translation: AAK28743.1
AF310267 Genomic DNA Translation: AAK28744.1
AF310268 Genomic DNA Translation: AAK28745.1
AF310269 Genomic DNA Translation: AAK28746.1
AF310270 Genomic DNA Translation: AAK28747.1
AF310271 Genomic DNA Translation: AAK28748.1
AF310272 Genomic DNA Translation: AAK28749.1
AF310273 Genomic DNA Translation: AAK28750.1
AF310274 Genomic DNA Translation: AAK28751.1
AF310275 Genomic DNA Translation: AAK28752.1
AF310276 Genomic DNA Translation: AAK28753.1
AF310277 Genomic DNA Translation: AAK28754.1
AF310278 Genomic DNA Translation: AAK28755.1
AF310279 Genomic DNA Translation: AAK28756.1
AF310280 Genomic DNA Translation: AAK28757.1
AF310281 Genomic DNA Translation: AAK28758.1
AF310282 Genomic DNA Translation: AAK28759.1
AF310283 Genomic DNA Translation: AAK28760.1
AF310284 Genomic DNA Translation: AAK28761.1
AF310285 Genomic DNA Translation: AAK28762.1
AF310286 Genomic DNA Translation: AAK28763.1
AF310287 Genomic DNA Translation: AAK28764.1
AF310288 Genomic DNA Translation: AAK28765.1
AF310289 Genomic DNA Translation: AAK28766.1
AF310290 Genomic DNA Translation: AAK28767.1
AF310291 Genomic DNA Translation: AAK28768.1
AF310292 Genomic DNA Translation: AAK28769.1
AF310293 Genomic DNA Translation: AAK28770.1
AF310294 Genomic DNA Translation: AAK28771.1
AF310295 Genomic DNA Translation: AAK28772.1
AF310296 Genomic DNA Translation: AAK28773.1
AF310297 Genomic DNA Translation: AAK28774.1
AF310298 Genomic DNA Translation: AAK28775.1
AF310299 Genomic DNA Translation: AAK28776.1
AF310300 Genomic DNA Translation: AAK28777.1
AF310301 Genomic DNA Translation: AAK28778.1
AF310302 Genomic DNA Translation: AAK28779.1
AF310303 Genomic DNA Translation: AAK28780.1
AF310304 Genomic DNA Translation: AAK28781.1
AF310305 Genomic DNA Translation: AAK28782.1
AF310306 Genomic DNA Translation: AAK28783.1
AF310307 Genomic DNA Translation: AAK28784.1
AF310308 Genomic DNA Translation: AAK28785.1
AF310309 Genomic DNA Translation: AAK28786.1
AF310310 Genomic DNA Translation: AAK28787.1
AF310311 Genomic DNA Translation: AAK28788.1
AF310312 Genomic DNA Translation: AAK28789.1
AF310313 Genomic DNA Translation: AAK28790.1
AF310314 Genomic DNA Translation: AAK28791.1
AF310315 Genomic DNA Translation: AAK28792.1
AF310316 Genomic DNA Translation: AAK28793.1
AF310317 Genomic DNA Translation: AAK28794.1
AF310318 Genomic DNA Translation: AAK28795.1
AF310319 Genomic DNA Translation: AAK28796.1
AF310320 Genomic DNA Translation: AAK28797.1
AF310321 Genomic DNA Translation: AAK28798.1
AF310322 Genomic DNA Translation: AAK28799.1
AF310323 Genomic DNA Translation: AAK28800.1
AF310324 Genomic DNA Translation: AAK28801.1
AF310325 Genomic DNA Translation: AAK28802.1
CCDSiCCDS1303.1 [Q9UBS9-1]
CCDS65726.1 [Q9UBS9-2]
PIRiJC7185
RefSeqiNP_001269679.1, NM_001282750.1
NP_001269680.1, NM_001282751.1
NP_055098.1, NM_014283.4 [Q9UBS9-1]
NP_057311.3, NM_016227.3 [Q9UBS9-2]
UniGeneiHs.204559

3D structure databases

ProteinModelPortaliQ9UBS9
SMRiQ9UBS9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119536, 24 interactors
IntActiQ9UBS9, 21 interactors
STRINGi9606.ENSP00000263688

PTM databases

GlyConnecti1775
iPTMnetiQ9UBS9
PhosphoSitePlusiQ9UBS9

Polymorphism and mutation databases

BioMutaiSUCO
DMDMi74761893

Proteomic databases

EPDiQ9UBS9
jPOSTiQ9UBS9
PaxDbiQ9UBS9
PeptideAtlasiQ9UBS9
PRIDEiQ9UBS9
ProteomicsDBi84053
84054 [Q9UBS9-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000263688; ENSP00000263688; ENSG00000094975 [Q9UBS9-1]
ENST00000367723; ENSP00000356696; ENSG00000094975 [Q9UBS9-2]
ENST00000608151; ENSP00000477484; ENSG00000094975 [Q9UBS9-2]
GeneIDi51430
KEGGihsa:51430
UCSCiuc001giq.6 human [Q9UBS9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51430
DisGeNETi51430
EuPathDBiHostDB:ENSG00000094975.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SUCO
HGNCiHGNC:1240 SUCO
HPAiHPA047251
neXtProtiNX_Q9UBS9
OpenTargetsiENSG00000094975
PharmGKBiPA25621

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1396 Eukaryota
ENOG41116S0 LUCA
GeneTreeiENSGT00390000013502
HOGENOMiHOG000070169
HOVERGENiHBG107549
InParanoidiQ9UBS9
OMAiLHATKKV
OrthoDBi890782at2759
PhylomeDBiQ9UBS9
TreeFamiTF105817

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SUCO human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
51430

Protein Ontology

More...
PROi
PR:Q9UBS9

Gene expression databases

BgeeiENSG00000094975 Expressed in 235 organ(s), highest expression level in caput epididymis
CleanExiHS_C1orf9
ExpressionAtlasiQ9UBS9 baseline and differential
GenevisibleiQ9UBS9 HS

Family and domain databases

Gene3Di2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR012919 SUN_dom
PfamiView protein in Pfam
PF07738 Sad1_UNC, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit
PROSITEiView protein in PROSITE
PS51469 SUN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSUCO_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UBS9
Secondary accession number(s): B2RNU4
, Q9BQB9, Q9BXQ2, Q9UL04
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 1, 2000
Last modified: January 16, 2019
This is version 128 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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