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Protein

Kidney-associated antigen 1

Gene

KAAG1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • immune response Source: UniProtKB

Names & Taxonomyi

Protein namesi
Recommended name:
Kidney-associated antigen 1
Alternative name(s):
RU2 antisense gene protein
Gene namesi
Name:KAAG1
Synonyms:RU2AS
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000146049.1
HGNCiHGNC:21031 KAAG1
MIMi608211 gene
neXtProtiNX_Q9UBP8

Pathology & Biotechi

Organism-specific databases

DisGeNETi353219
OpenTargetsiENSG00000146049
PharmGKBiPA134915618

Polymorphism and mutation databases

BioMutaiKAAG1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002746691 – 84Kidney-associated antigen 1Add BLAST84

Proteomic databases

PaxDbiQ9UBP8
PRIDEiQ9UBP8
ProteomicsDBi84027

Expressioni

Tissue specificityi

Expressed in testis and kidney, and, at lower levels, in urinary bladder and liver. Expressed by a high proportion of tumors of various histologic origin, including melanomas, sarcomas and colorectal carcinomas.1 Publication

Gene expression databases

BgeeiENSG00000146049 Expressed in 22 organ(s), highest expression level in adult mammalian kidney
CleanExiHS_KAAG1
GenevisibleiQ9UBP8 HS

Organism-specific databases

HPAiHPA036021

Interactioni

Protein-protein interaction databases

BioGridi131666, 1 interactor
IntActiQ9UBP8, 1 interactor
STRINGi9606.ENSP00000274766

Structurei

3D structure databases

ProteinModelPortaliQ9UBP8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi33 – 36Poly-Ala4

Phylogenomic databases

eggNOGiENOG410JGC7 Eukaryota
ENOG41118AS LUCA
GeneTreeiENSGT00390000011791
HOGENOMiHOG000113188
InParanoidiQ9UBP8
OMAiAPCEEGV
OrthoDBiEOG091G1731
PhylomeDBiQ9UBP8
TreeFamiTF340885

Family and domain databases

InterProiView protein in InterPro
IPR029407 KAAG1
PfamiView protein in Pfam
PF15354 KAAG1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9UBP8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDDAAPRVE GVPVAVHKHA LHDGLRQVAG PGAAAAHLPR WPPPQLAASR
60 70 80
REAPPLSQRP HRTQGAGSPP ETNEKLTNPQ VKEK
Length:84
Mass (Da):8,969
Last modified:May 1, 2000 - v1
Checksum:i70B739F173A9E560
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF181720 Genomic DNA Translation: AAF23611.1
AF181722 mRNA Translation: AAF23613.1
AL359713 Genomic DNA No translation available.
CCDSiCCDS4551.1
RefSeqiNP_851854.1, NM_181337.3
UniGeneiHs.697888

Genome annotation databases

EnsembliENST00000274766; ENSP00000274766; ENSG00000146049
GeneIDi353219
KEGGihsa:353219
UCSCiuc003ndz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF181720 Genomic DNA Translation: AAF23611.1
AF181722 mRNA Translation: AAF23613.1
AL359713 Genomic DNA No translation available.
CCDSiCCDS4551.1
RefSeqiNP_851854.1, NM_181337.3
UniGeneiHs.697888

3D structure databases

ProteinModelPortaliQ9UBP8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi131666, 1 interactor
IntActiQ9UBP8, 1 interactor
STRINGi9606.ENSP00000274766

Polymorphism and mutation databases

BioMutaiKAAG1

Proteomic databases

PaxDbiQ9UBP8
PRIDEiQ9UBP8
ProteomicsDBi84027

Protocols and materials databases

DNASUi353219
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000274766; ENSP00000274766; ENSG00000146049
GeneIDi353219
KEGGihsa:353219
UCSCiuc003ndz.1 human

Organism-specific databases

CTDi353219
DisGeNETi353219
EuPathDBiHostDB:ENSG00000146049.1
GeneCardsiKAAG1
H-InvDBiHIX0005620
HGNCiHGNC:21031 KAAG1
HPAiHPA036021
MIMi608211 gene
neXtProtiNX_Q9UBP8
OpenTargetsiENSG00000146049
PharmGKBiPA134915618
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JGC7 Eukaryota
ENOG41118AS LUCA
GeneTreeiENSGT00390000011791
HOGENOMiHOG000113188
InParanoidiQ9UBP8
OMAiAPCEEGV
OrthoDBiEOG091G1731
PhylomeDBiQ9UBP8
TreeFamiTF340885

Miscellaneous databases

GenomeRNAii353219
PROiPR:Q9UBP8
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000146049 Expressed in 22 organ(s), highest expression level in adult mammalian kidney
CleanExiHS_KAAG1
GenevisibleiQ9UBP8 HS

Family and domain databases

InterProiView protein in InterPro
IPR029407 KAAG1
PfamiView protein in Pfam
PF15354 KAAG1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiKAAG1_HUMAN
AccessioniPrimary (citable) accession number: Q9UBP8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: May 1, 2000
Last modified: September 12, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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