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Entry version 183 (17 Jun 2020)
Sequence version 1 (01 May 2000)
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Protein

Tuftelin-interacting protein 11

Gene

TFIP11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processBiomineralization, mRNA processing, mRNA splicing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-72163 mRNA Splicing - Major Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tuftelin-interacting protein 11
Alternative name(s):
Septin and tuftelin-interacting protein 1
Short name:
STIP-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TFIP11
Synonyms:STIP
ORF Names:HSPC006
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000100109.16

Human Gene Nomenclature Database

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HGNCi
HGNC:17165 TFIP11

Online Mendelian Inheritance in Man (OMIM)

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MIMi
612747 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UBB9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus, Spliceosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
24144

Open Targets

More...
OpenTargetsi
ENSG00000100109

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA38441

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

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Pharosi
Q9UBB9 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
TFIP11

Domain mapping of disease mutations (DMDM)

More...
DMDMi
22096235

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000725011 – 837Tuftelin-interacting protein 11Add BLAST837

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2PhosphoserineBy similarity1
Modified residuei59PhosphoserineCombined sources1
Modified residuei98PhosphoserineCombined sources1
Modified residuei144PhosphoserineCombined sources1
Modified residuei210PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UBB9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UBB9

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q9UBB9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UBB9

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q9UBB9

PeptideAtlas

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PeptideAtlasi
Q9UBB9

PRoteomics IDEntifications database

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PRIDEi
Q9UBB9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83928 [Q9UBB9-1]
83929 [Q9UBB9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UBB9

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
Q9UBB9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UBB9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000100109 Expressed in testis and 211 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q9UBB9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UBB9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000100109 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Identified in the spliceosome C complex.

Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors.

Interacts with TUFT1.

Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex.

Interacts with GCFC2.

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q9UBB9
With#Exp.IntAct
AARD [Q4LEZ3]3EBI-1105213,EBI-5463075
ABI2 [Q9NYB9]6EBI-1105213,EBI-743598
ABLIM3 - isoform 2 [O94929-2]3EBI-1105213,EBI-11961672
AIMP2 [Q13155]6EBI-1105213,EBI-745226
AP1M1 [Q9BXS5]3EBI-1105213,EBI-541426
ARMCX1 [Q9P291]4EBI-1105213,EBI-2843626
ATP5PO [P48047]3EBI-1105213,EBI-355815
ATPAF2 [Q8N5M1]3EBI-1105213,EBI-1166928
AXIN1 [A0A0S2Z4M1]3EBI-1105213,EBI-16429430
AXIN1 [O15169]3EBI-1105213,EBI-710484
BAZ2B [A0A0A0MR97]3EBI-1105213,EBI-11985607
BHLHA9 [Q7RTU4]3EBI-1105213,EBI-17508719
BMF [Q96LC9]7EBI-1105213,EBI-3919268
BRD1 [O95696]3EBI-1105213,EBI-714754
BYSL [Q13895]3EBI-1105213,EBI-358049
C1orf109 [Q9NX04]6EBI-1105213,EBI-8643161
C2CD6 [Q53TS8]3EBI-1105213,EBI-739879
CARD9 [Q9H257]3EBI-1105213,EBI-751319
CARD9 - isoform 2 [Q9H257-2]3EBI-1105213,EBI-11530605
CAVIN3 [Q969G5]3EBI-1105213,EBI-3893101
CBX8 [Q9HC52]3EBI-1105213,EBI-712912
CCDC102B [Q68D86]3EBI-1105213,EBI-10171570
CCDC116 [Q8IYX3]3EBI-1105213,EBI-744311
CCDC120 [Q96HB5]3EBI-1105213,EBI-744556
CCDC121 [Q6ZUS5]7EBI-1105213,EBI-2836982
CCDC13 [Q8IYE1]3EBI-1105213,EBI-10961312
CCDC146 [Q8IYE0]3EBI-1105213,EBI-10749669
CCDC146 - isoform 2 [Q8IYE0-2]3EBI-1105213,EBI-10247802
CCDC151 [A5D8V7]6EBI-1105213,EBI-8466445
CCDC151 - isoform 2 [A5D8V7-2]3EBI-1105213,EBI-10173824
CCDC196 [A0A1B0GWI1]3EBI-1105213,EBI-10181422
CCDC42 [Q96M95]5EBI-1105213,EBI-747041
CCDC57 - isoform 2 [Q2TAC2-2]3EBI-1105213,EBI-10961624
CCDC6 [Q16204]3EBI-1105213,EBI-1045350
CCDC68 [Q9H2F9]8EBI-1105213,EBI-2813327
CCDC96 [Q2M329]4EBI-1105213,EBI-12382974
CCHCR1 - isoform 3 [Q8TD31-3]8EBI-1105213,EBI-10175300
CCND3 [P30281]5EBI-1105213,EBI-375013
CCNG1 [P51959]3EBI-1105213,EBI-3905829
CCNL1 [Q9UK58]3EBI-1105213,EBI-2836773
CDKN1A [P38936]3EBI-1105213,EBI-375077
CDR2L [Q86X02]3EBI-1105213,EBI-11063830
CENPU [Q71F23]4EBI-1105213,EBI-2515234
CEP57 [Q86XR8]4EBI-1105213,EBI-308614
CEP57 - isoform 3 [Q86XR8-3]3EBI-1105213,EBI-11752486
CEP57L1 [Q8IYX8]3EBI-1105213,EBI-1104570
CEP95 [Q96GE4]3EBI-1105213,EBI-372775
CFAP206 [Q8IYR0]4EBI-1105213,EBI-749051
COQ8A [Q8NI60]13EBI-1105213,EBI-745535
COX5B [P10606]5EBI-1105213,EBI-1053725
CT55 [Q8WUE5]3EBI-1105213,EBI-6873363
CWF19L2 [Q2TBE0]3EBI-1105213,EBI-5453285
DAXX [Q9UER7]3EBI-1105213,EBI-77321
DDX25 [Q9UHL0]3EBI-1105213,EBI-8787165
DES [P17661]3EBI-1105213,EBI-1055572
DISC1 [Q9NRI5]3EBI-1105213,EBI-529989
DPPA3 [Q6W0C5]3EBI-1105213,EBI-12082590
DTNB - isoform 5 [O60941-5]3EBI-1105213,EBI-11984733
EIF3D [O15371]3EBI-1105213,EBI-353818
EPM2AIP1 [Q7L775]3EBI-1105213,EBI-6255981
EXOC3L1 [Q86VI1]3EBI-1105213,EBI-2813180
EXOC8 [Q8IYI6]3EBI-1105213,EBI-742102
EXOSC5 [Q9NQT4]3EBI-1105213,EBI-371876
FAM13C [Q8NE31]5EBI-1105213,EBI-751248
FAM156A [Q8NDB6]3EBI-1105213,EBI-749727
FAM161A [Q3B820]9EBI-1105213,EBI-719941
FAM161B [Q96MY7]3EBI-1105213,EBI-7225287
FAM50B [Q9Y247]3EBI-1105213,EBI-742802
FAM81A [Q8TBF8]3EBI-1105213,EBI-11993062
FAM90A1 [Q86YD7]3EBI-1105213,EBI-6658203
FGA - isoform 2 [P02671-2]3EBI-1105213,EBI-9640259
GADD45GIP1 [Q8TAE8]3EBI-1105213,EBI-372506
GAS2L2 [Q8NHY3]3EBI-1105213,EBI-7960826
GCC1 [Q96CN9]3EBI-1105213,EBI-746252
GCFC2 [P16383]5EBI-1105213,EBI-954074
GEM [P55040]7EBI-1105213,EBI-744104
GFAP [P14136]3EBI-1105213,EBI-744302
GNG4 [B1APZ0]3EBI-1105213,EBI-10175453
GOLGA1 [Q92805]6EBI-1105213,EBI-6164177
GPS2 [Q13227]6EBI-1105213,EBI-713355
GSE1 [Q14687]3EBI-1105213,EBI-372619
HAUS1 [Q96CS2]3EBI-1105213,EBI-2514791
hCG_1987119 [A0A024R8L2]3EBI-1105213,EBI-14103818
HDAC4 - isoform 2 [P56524-2]3EBI-1105213,EBI-11953488
HIP1R - isoform 2 [O75146-2]3EBI-1105213,EBI-12292427
HMG20B [Q9P0W2]3EBI-1105213,EBI-713401
HOOK1 [Q9UJC3]8EBI-1105213,EBI-746704
HSF2BP [O75031]3EBI-1105213,EBI-7116203
IKBIP [Q70UQ0]3EBI-1105213,EBI-2557212
IL16 - isoform 2 [Q14005-2]3EBI-1105213,EBI-17178971
IMP3 [Q9NV31]4EBI-1105213,EBI-747481
JRK - isoform 2 [O75564-2]3EBI-1105213,EBI-17181882
KANK2 [Q63ZY3]3EBI-1105213,EBI-2556193
KANSL1 [Q7Z3B3]5EBI-1105213,EBI-740244
KAT5 [Q92993]3EBI-1105213,EBI-399080
KDM1A [O60341]3EBI-1105213,EBI-710124
KIF3C [O14782]3EBI-1105213,EBI-1104854
KIF9 [Q9HAQ2]3EBI-1105213,EBI-8472129
KIFC3 - isoform 4 [Q9BVG8-5]3EBI-1105213,EBI-14069005
KIZ [Q2M2Z5]3EBI-1105213,EBI-2554344
KRT1 [P04264]3EBI-1105213,EBI-298429
KRT20 [P35900]7EBI-1105213,EBI-742094
KRT6A [P02538]10EBI-1105213,EBI-702198
KRT6B [P04259]6EBI-1105213,EBI-740907
KRT6C [P48668]3EBI-1105213,EBI-2564105
KRT8 [P05787]3EBI-1105213,EBI-297852
LATS1 [Q6PJG3]3EBI-1105213,EBI-10253976
LCA5 [Q86VQ0]4EBI-1105213,EBI-6658186
LCA5L [O95447]6EBI-1105213,EBI-8473670
LENG1 [Q96BZ8]3EBI-1105213,EBI-726510
LIN37 [Q96GY3]3EBI-1105213,EBI-748884
LMNB2 [Q03252]3EBI-1105213,EBI-2830427
LMO1 [P25800]7EBI-1105213,EBI-8639312
LMO2 - isoform 3 [P25791-3]3EBI-1105213,EBI-11959475
LMO4 [P61968]6EBI-1105213,EBI-2798728
LOC729862 [Q0VAF8]3EBI-1105213,EBI-10226726
LOC729862 [Q0VAF9]3EBI-1105213,EBI-10226748
LYSMD1 [Q96S90]3EBI-1105213,EBI-10293291
MAB21L2 [Q9Y586]3EBI-1105213,EBI-6659161
METTL17 [Q9H7H0]5EBI-1105213,EBI-749353
MFAP1 [P55081]3EBI-1105213,EBI-1048159
MGC50722 [Q8IVT4]3EBI-1105213,EBI-14086479
MKRN3 [Q13064]3EBI-1105213,EBI-2340269
MRPL11 [Q9Y3B7]3EBI-1105213,EBI-5453723
MTFR2 [Q6P444]3EBI-1105213,EBI-10252703
MXD3 [Q9BW11]3EBI-1105213,EBI-741574
MYOM1 - isoform 2 [P52179-2]3EBI-1105213,EBI-12010196
NDC80 [O14777]6EBI-1105213,EBI-715849
NEK6 - isoform 4 [Q9HC98-4]3EBI-1105213,EBI-11750983
NFKBID [Q8NI38]3EBI-1105213,EBI-10271199
NFU1 [Q9UMS0]6EBI-1105213,EBI-725252
NSMF - isoform 2 [Q6X4W1-2]3EBI-1105213,EBI-12028784
NUP88 [Q99567]3EBI-1105213,EBI-726178
OIP5 [O43482]6EBI-1105213,EBI-536879
PBX3 [Q96AL5]3EBI-1105213,EBI-741171
PBX4 [Q9BYU1]9EBI-1105213,EBI-10302990
PDE4DIP [Q8TBR0]3EBI-1105213,EBI-10240575
PHF1 [O43189]3EBI-1105213,EBI-530034
PIBF1 [Q4G0R1]3EBI-1105213,EBI-14066006
PICK1 [Q9NRD5]3EBI-1105213,EBI-79165
PKN3 [Q6P5Z2]3EBI-1105213,EBI-1384335
PLK4 [O00444]3EBI-1105213,EBI-746202
POLL - isoform 2 [Q9UGP5-2]3EBI-1105213,EBI-10320765
POLR1C [O15160]5EBI-1105213,EBI-1055079
POM121 - isoform 2 [Q96HA1-2]3EBI-1105213,EBI-11956563
PPFIA3 [O75145]3EBI-1105213,EBI-1763225
PPP1R18 [Q6NYC8]3EBI-1105213,EBI-2557469
PRPF31 [Q8WWY3]12EBI-1105213,EBI-1567797
PSMA4 [P25789]3EBI-1105213,EBI-359310
PSMC5 [P62195]3EBI-1105213,EBI-357745
PSTPIP1 [A0A0S2Z528]3EBI-1105213,EBI-16430249
PTCD1 [O75127]3EBI-1105213,EBI-2560233
RCOR3 [Q9P2K3]3EBI-1105213,EBI-743428
RHNO1 [Q9BSD3]6EBI-1105213,EBI-9658624
RIN1 [Q13671]3EBI-1105213,EBI-366017
RNF6 [A0A0S2Z4G9]3EBI-1105213,EBI-16428950
RRP7A [Q9Y3A4]5EBI-1105213,EBI-7223720
RUNX1T1 - isoform MTG8A [Q06455-2]3EBI-1105213,EBI-11984663
RXRB - isoform 2 [P28702-3]3EBI-1105213,EBI-16429492
S100P [P25815]3EBI-1105213,EBI-743700
SAP30BP [Q9UHR5]4EBI-1105213,EBI-751683
SCNM1 [Q9BWG6]5EBI-1105213,EBI-748391
SFR1 [Q86XK3]4EBI-1105213,EBI-1104535
SGF29 [Q96ES7]3EBI-1105213,EBI-743117
SH2D4A [Q9H788]8EBI-1105213,EBI-747035
SH2D4A - isoform 2 [Q9H788-2]3EBI-1105213,EBI-10308083
SH3GLB1 [Q9Y371]7EBI-1105213,EBI-2623095
SMARCE1 [Q969G3]7EBI-1105213,EBI-455078
SNAPIN [O95295]3EBI-1105213,EBI-296723
SNRPB - isoform SM-B [P14678-2]6EBI-1105213,EBI-372475
SNW1 [Q13573]7EBI-1105213,EBI-632715
SNX20 [Q7Z614]4EBI-1105213,EBI-744896
SNX32 [Q86XE0]3EBI-1105213,EBI-8099743
SOGA1 - isoform 4 [O94964-4]3EBI-1105213,EBI-14083835
SPG21 [Q9NZD8]3EBI-1105213,EBI-742688
SSX2IP [Q9Y2D8]4EBI-1105213,EBI-2212028
STRA8 [Q7Z7C7]3EBI-1105213,EBI-12036261
STRN [O43815]3EBI-1105213,EBI-1046642
TBC1D30 - isoform 2 [Q9Y2I9-2]3EBI-1105213,EBI-17455779
TBRG4 [Q969Z0]3EBI-1105213,EBI-702328
TCAF1 [Q9Y4C2]3EBI-1105213,EBI-750484
TCAF1 - isoform 2 [Q9Y4C2-2]3EBI-1105213,EBI-11974855
TFPT [A0A024R4Q5]4EBI-1105213,EBI-11527449
TFPT - isoform 2 [P0C1Z6-2]3EBI-1105213,EBI-10178002
THAP7 [Q9BT49]7EBI-1105213,EBI-741350
THAP8 [Q8NA92]5EBI-1105213,EBI-717429
TNNT1 [P13805]4EBI-1105213,EBI-726527
TRAF3IP3 [Q9Y228]4EBI-1105213,EBI-765817
TRIM45 - isoform 2 [Q9H8W5-2]3EBI-1105213,EBI-11993364
TRIML2 [Q8N7C3]3EBI-1105213,EBI-11059915
TSG101 [Q99816]3EBI-1105213,EBI-346882
TSGA10IP [Q3SY00]3EBI-1105213,EBI-10241197
TSHZ2 [Q9NRE2]3EBI-1105213,EBI-10687282
TSHZ3 [Q63HK5]7EBI-1105213,EBI-9053916
TSPYL4 [Q9UJ04]3EBI-1105213,EBI-308511
TXLNA [P40222]8EBI-1105213,EBI-359793
TXN2 [Q99757]3EBI-1105213,EBI-2932492
UBTFL1 [P0CB47]3EBI-1105213,EBI-17208936
USP2 [O75604]3EBI-1105213,EBI-743272
VPS37C [A5D8V6]3EBI-1105213,EBI-2559305
VPS39 - isoform 2 [Q96JC1-2]3EBI-1105213,EBI-11962886
WASHC3 [Q9Y3C0]3EBI-1105213,EBI-712969
ZC2HC1C [Q53FD0]4EBI-1105213,EBI-740767
ZFYVE26 - isoform 5 [Q68DK2-5]3EBI-1105213,EBI-8656416
ZGPAT [A0A0S2Z6H0]3EBI-1105213,EBI-16428984
ZGPAT [Q8N5A5]5EBI-1105213,EBI-3439227
ZGPAT - isoform 2 [Q8N5A5-2]9EBI-1105213,EBI-10183064
ZMAT2 [Q96NC0]4EBI-1105213,EBI-2682299
ZNF417 [Q8TAU3]4EBI-1105213,EBI-740727
ZNF572 [Q7Z3I7]3EBI-1105213,EBI-10172590
ZNF587 [Q96SQ5]3EBI-1105213,EBI-6427977
ZNF777 [Q9ULD5]3EBI-1105213,EBI-11975599
ZSCAN12 [O43309]3EBI-1105213,EBI-1210440

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
117294, 184 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9UBB9

Protein interaction database and analysis system

More...
IntActi
Q9UBB9, 271 interactors

Molecular INTeraction database

More...
MINTi
Q9UBB9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000384421

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9UBB9 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9UBB9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini149 – 195G-patchPROSITE-ProRule annotationAdd BLAST47

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 50Required for interaction with DHX151 PublicationAdd BLAST50
Regioni710 – 734Required for nuclear speckle localizationBy similarityAdd BLAST25

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi700 – 705Nuclear localization signalBy similarity6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi15 – 19Poly-Asp5

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TFP11/STIP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2184 Eukaryota
ENOG410XP4Y LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012739

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007977_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UBB9

KEGG Orthology (KO)

More...
KOi
K13103

Identification of Orthologs from Complete Genome Data

More...
OMAi
VWEWHEL

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UBB9

TreeFam database of animal gene trees

More...
TreeFami
TF314887

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000467 G_patch_dom
IPR022783 GCFC_dom
IPR024933 STIP
IPR022159 STIP/TFIP11_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01585 G-patch, 1 hit
PF07842 GCFC, 1 hit
PF12457 TIP_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017706 TFIP11, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00443 G_patch, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50174 G_PATCH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9UBB9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSLSHLYRDG EGRIDDDDDE RENFEITDWD LQNEFNPNRQ RHWQTKEEAT
60 70 80 90 100
YGVWAERDSD DERPSFGGKR ARDYSAPVNF ISAGLKKGAA EEAELEDSDD
110 120 130 140 150
EEKPVKQDDF PKDFGPRKLK TGGNFKPSQK GFAGGTKSFM DFGSWERHTK
160 170 180 190 200
GIGQKLLQKM GYVPGRGLGK NAQGIINPIE AKQRKGKGAV GAYGSERTTQ
210 220 230 240 250
SMQDFPVVDS EEEAEEEFQK ELSQWRKDPS GSKKKPKYSY KTVEELKAKG
260 270 280 290 300
RISKKLTAPQ KELSQVKVID MTGREQKVYY SYSQISHKHN VPDDGLPLQS
310 320 330 340 350
QQLPQSGKEA KAPGFALPEL EHNLQLLIDL TEQEIIQNDR QLQYERDMVV
360 370 380 390 400
NLFHELEKMT EVLDHEERVI SNLSKVLEMV EECERRMQPD CSNPLTLDEC
410 420 430 440 450
ARIFETLQDK YYEEYRMSDR VDLAVAIVYP LMKEYFKEWD PLKDCTYGTE
460 470 480 490 500
IISKWKSLLE NDQLLSHGGQ DLSADAFHRL IWEVWMPFVR NIVTQWQPRN
510 520 530 540 550
CDPMVDFLDS WVHIIPVWIL DNILDQLIFP KLQKEVENWN PLTDTVPIHS
560 570 580 590 600
WIHPWLPLMQ ARLEPLYSPI RSKLSSALQK WHPSDSSAKL ILQPWKDVFT
610 620 630 640 650
PGSWEAFMVK NIVPKLGMCL GELVINPHQQ HMDAFYWVID WEGMISVSSL
660 670 680 690 700
VGLLEKHFFP KWLQVLCSWL SNSPNYEEIT KWYLGWKSMF SDQVLAHPSV
710 720 730 740 750
KDKFNEALDI MNRAVSSNVG AYMQPGAREN IAYLTHTERR KDFQYEAMQE
760 770 780 790 800
RREAENMAQR GIGVAASSVP MNFKDLIETK AEEHNIVFMP VIGKRHEGKQ
810 820 830
LYTFGRIVIY IDRGVVFVQG EKTWVPTSLQ SLIDMAK
Length:837
Mass (Da):96,820
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF4C44F8411517289
GO
Isoform 2 (identifier: Q9UBB9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-641: Missing.
     642-663: EGMISVSSLVGLLEKHFFPKWL → MATSEILPSFVATMDASNFSFW

Show »
Length:196
Mass (Da):22,431
Checksum:i0E4DBC70BB97D704
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6XM96F6XM96_HUMAN
Tuftelin-interacting protein 11
TFIP11
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y4U8H0Y4U8_HUMAN
Tuftelin-interacting protein 11
TFIP11
190Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6UQ07F6UQ07_HUMAN
Tuftelin-interacting protein 11
TFIP11
42Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6SQZ1F6SQZ1_HUMAN
Tuftelin-interacting protein 11
TFIP11
88Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6UKU9F6UKU9_HUMAN
Tuftelin-interacting protein 11
TFIP11
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_054069177N → S. Corresponds to variant dbSNP:rs6005062Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0039981 – 641Missing in isoform 2. 1 PublicationAdd BLAST641
Alternative sequenceiVSP_003999642 – 663EGMIS…FPKWL → MATSEILPSFVATMDASNFS FW in isoform 2. 1 PublicationAdd BLAST22

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF070662 mRNA Translation: AAD20968.1
AL080147 mRNA Translation: CAB45740.1
AL050258 mRNA Translation: CAB43360.1
BT007274 mRNA Translation: AAP35938.1
CT841511 mRNA Translation: CAJ86441.1
Z95115, Z99714 Genomic DNA Translation: CAI17979.1
Z99714, Z95115 Genomic DNA Translation: CAI17878.1
CH471095 Genomic DNA Translation: EAW59723.1
BC011599 mRNA Translation: AAH11599.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13838.1 [Q9UBB9-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
T12531

NCBI Reference Sequences

More...
RefSeqi
NP_001008697.1, NM_001008697.2 [Q9UBB9-1]
NP_001333786.1, NM_001346857.1 [Q9UBB9-1]
NP_001333787.1, NM_001346858.1 [Q9UBB9-1]
NP_001333788.1, NM_001346859.1 [Q9UBB9-1]
NP_001333790.1, NM_001346861.1 [Q9UBB9-1]
NP_036275.1, NM_012143.3 [Q9UBB9-1]
XP_011528381.1, XM_011530079.1
XP_016884224.1, XM_017028735.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000405938; ENSP00000384297; ENSG00000100109 [Q9UBB9-1]
ENST00000407148; ENSP00000385861; ENSG00000100109 [Q9UBB9-1]
ENST00000407431; ENSP00000383892; ENSG00000100109 [Q9UBB9-1]
ENST00000407690; ENSP00000384421; ENSG00000100109 [Q9UBB9-1]
ENST00000619735; ENSP00000480171; ENSG00000100109 [Q9UBB9-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
24144

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:24144

UCSC genome browser

More...
UCSCi
uc003acr.4 human [Q9UBB9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF070662 mRNA Translation: AAD20968.1
AL080147 mRNA Translation: CAB45740.1
AL050258 mRNA Translation: CAB43360.1
BT007274 mRNA Translation: AAP35938.1
CT841511 mRNA Translation: CAJ86441.1
Z95115, Z99714 Genomic DNA Translation: CAI17979.1
Z99714, Z95115 Genomic DNA Translation: CAI17878.1
CH471095 Genomic DNA Translation: EAW59723.1
BC011599 mRNA Translation: AAH11599.1
CCDSiCCDS13838.1 [Q9UBB9-1]
PIRiT12531
RefSeqiNP_001008697.1, NM_001008697.2 [Q9UBB9-1]
NP_001333786.1, NM_001346857.1 [Q9UBB9-1]
NP_001333787.1, NM_001346858.1 [Q9UBB9-1]
NP_001333788.1, NM_001346859.1 [Q9UBB9-1]
NP_001333790.1, NM_001346861.1 [Q9UBB9-1]
NP_036275.1, NM_012143.3 [Q9UBB9-1]
XP_011528381.1, XM_011530079.1
XP_016884224.1, XM_017028735.1

3D structure databases

SMRiQ9UBB9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi117294, 184 interactors
CORUMiQ9UBB9
IntActiQ9UBB9, 271 interactors
MINTiQ9UBB9
STRINGi9606.ENSP00000384421

PTM databases

iPTMnetiQ9UBB9
MetOSiteiQ9UBB9
PhosphoSitePlusiQ9UBB9

Polymorphism and mutation databases

BioMutaiTFIP11
DMDMi22096235

Proteomic databases

EPDiQ9UBB9
jPOSTiQ9UBB9
MassIVEiQ9UBB9
MaxQBiQ9UBB9
PaxDbiQ9UBB9
PeptideAtlasiQ9UBB9
PRIDEiQ9UBB9
ProteomicsDBi83928 [Q9UBB9-1]
83929 [Q9UBB9-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
9983 111 antibodies

The DNASU plasmid repository

More...
DNASUi
24144

Genome annotation databases

EnsembliENST00000405938; ENSP00000384297; ENSG00000100109 [Q9UBB9-1]
ENST00000407148; ENSP00000385861; ENSG00000100109 [Q9UBB9-1]
ENST00000407431; ENSP00000383892; ENSG00000100109 [Q9UBB9-1]
ENST00000407690; ENSP00000384421; ENSG00000100109 [Q9UBB9-1]
ENST00000619735; ENSP00000480171; ENSG00000100109 [Q9UBB9-1]
GeneIDi24144
KEGGihsa:24144
UCSCiuc003acr.4 human [Q9UBB9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
24144
DisGeNETi24144
EuPathDBiHostDB:ENSG00000100109.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TFIP11
HGNCiHGNC:17165 TFIP11
HPAiENSG00000100109 Low tissue specificity
MIMi612747 gene
neXtProtiNX_Q9UBB9
OpenTargetsiENSG00000100109
PharmGKBiPA38441

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2184 Eukaryota
ENOG410XP4Y LUCA
GeneTreeiENSGT00390000012739
HOGENOMiCLU_007977_1_1_1
InParanoidiQ9UBB9
KOiK13103
OMAiVWEWHEL
PhylomeDBiQ9UBB9
TreeFamiTF314887

Enzyme and pathway databases

ReactomeiR-HSA-72163 mRNA Splicing - Major Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
24144 644 hits in 789 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TFIP11 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TFIP11

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
24144
PharosiQ9UBB9 Tbio

Protein Ontology

More...
PROi
PR:Q9UBB9
RNActiQ9UBB9 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000100109 Expressed in testis and 211 other tissues
ExpressionAtlasiQ9UBB9 baseline and differential
GenevisibleiQ9UBB9 HS

Family and domain databases

InterProiView protein in InterPro
IPR000467 G_patch_dom
IPR022783 GCFC_dom
IPR024933 STIP
IPR022159 STIP/TFIP11_N
PfamiView protein in Pfam
PF01585 G-patch, 1 hit
PF07842 GCFC, 1 hit
PF12457 TIP_N, 1 hit
PIRSFiPIRSF017706 TFIP11, 1 hit
SMARTiView protein in SMART
SM00443 G_patch, 1 hit
PROSITEiView protein in PROSITE
PS50174 G_PATCH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTFP11_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UBB9
Secondary accession number(s): O95908
, Q20WL0, Q5H8V8, Q9UGV7, Q9Y2Q8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: May 1, 2000
Last modified: June 17, 2020
This is version 183 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
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