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Protein

Transcriptional regulator ATRX homolog

Gene

xnp-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for embryonic development and gonadogenesis. Also, functions redundantly with the transcriptional repressor lin-35 to regulate somatic gonad development.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi496 – 503ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Helicase, Hydrolase
Biological processDNA damage, DNA repair
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcriptional regulator ATRX homolog (EC:3.6.4.12)
Alternative name(s):
ATP-dependent helicase xnp-1
X-linked nuclear protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:xnp-1Imported
ORF Names:B0041.7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

WormBase

More...
WormBasei
B0041.7 ; CE17314 ; WBGene00006961 ; xnp-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Temperature-sensitive with 38% embryonic lethality at 25 degrees Celsius (PubMed:15649460). A large proportion of surviving animals are sterile. Surviving animals also have gonad developmental defects such as defective gonadal arm growth and as a result irregular distal tip cell migration, and 24% of animals had a protruding vulva phenotype (PubMed:15649460). Reduced brood size (PubMed:15328017). Double knockout with lin-35 results in 43% embryonic lethality (PubMed:15328017). Surviving animals develop slowly, are small, sterile and display male and female gonad developmental defects characterized by shorter gonadal arms, fewer germ cells, an everted vulva phenotype, and failed formation of sheath and spermathecal cells (PubMed:15328017). RNAi-mediated knockdown of lin-35 or hpl-2 results in larval arrest at 25 degrees Celsius in an xpn-1 mutant background (PubMed:15649460).2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi1130R → K in fd2; viable. Gonad morphological defects in a lin-35 RNAi background. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000743081 – 1359Transcriptional regulator ATRX homologAdd BLAST1359

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9U7E0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9U7E0

PeptideAtlas

More...
PeptideAtlasi
Q9U7E0

PRoteomics IDEntifications database

More...
PRIDEi
Q9U7E0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9U7E0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in most cells during embryonic development (PubMed:15328017, PubMed:15649460). First expressed at around the 100-200 cell stage of embryogenesis (PubMed:15328017, PubMed:15649460). Expression was absent or reduced in intestinal cell lineages during this time. Highly expressed in neuronal cells of the head, ventral nerve cord and tail during the late stages of embryogenesis (PubMed:15328017). Highly expressed in all dividing cells after hatching (PubMed:15649460). Highly expressed in the P lineage during the L1 stage of larval development (PubMed:15649460). During larval development, mainly expressed in the neurons, but there is also high expression in the junctional cells of the spermatheca and uterus, and weak expression in cells of the somatic gonad including the distal tip cells (PubMed:15328017).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00006961 Expressed in 5 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.B0041.7

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9U7E0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9U7E0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini483 – 685Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST203
Domaini951 – 1134Helicase C-terminalPROSITE-ProRule annotationAdd BLAST184

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi636 – 639DEAH box4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi67 – 70Poly-Asp4
Compositional biasi266 – 272Poly-Glu7
Compositional biasi276 – 281Poly-Lys6
Compositional biasi372 – 375Poly-Lys4
Compositional biasi603 – 608Poly-Lys6
Compositional biasi859 – 862Poly-Lys4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1015 Eukaryota
COG0553 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000199608

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9U7E0

KEGG Orthology (KO)

More...
KOi
K10779

Database of Orthologous Groups

More...
OrthoDBi
EOG091G01G9

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9U7E0

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00079 HELICc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9U7E0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRVGVSESED SDGHVIEDED LEMARQIENE RKEKRAQKLK EKREREGKPP
60 70 80 90 100
PKKRPAKKRK ASSSEEDDDD EEESPRKSSK KSRKRAKSES ESDESDEEED
110 120 130 140 150
RKKSKSKKKV DQKKKEKSKK KRTTSSSEDE DSDEEREQKS KKKSKKTKKQ
160 170 180 190 200
TSSESSEESE EERKVKKSKK NKEKSVKKRA ETSEESDEDE KPSKKSKKGL
210 220 230 240 250
KKKAKSESES ESEDEKEVKK SKKKSKKVVK KESESEDEAP EKKKTEKRKR
260 270 280 290 300
SKTSSEESSE SEKSDEEEEE KESSPKPKKK KPLAVKKLSS DEESEESDVE
310 320 330 340 350
VLPQKKKRGA VTLISDSEDE KDQKSESEAS DVEEKVSKKK AKKQESSESG
360 370 380 390 400
SDSSEGSITV NRKSKKKEKP EKKKKGIIMD SSKLQKETID AERAEKERRK
410 420 430 440 450
RLEKKQKEFN GIVLEEGEDL TEMLTGTSSQ RKLKSVVLDP DSSTVDEESK
460 470 480 490 500
KPVEVHNSLV RILKPHQAHG IQFMYDCACE SLDRLDTEGS GGILAHCMGL
510 520 530 540 550
GKTLQVITFL HTVLMHEKIG EKCKRVLVVV PKNVIINWFK EFQKWLVDND
560 570 580 590 600
EELDTIDVNE LDSYKTIEDR RRALKAWHSS KTPSVMIIGY DLFRILTVED
610 620 630 640 650
DPKKKKPKNR NRRLEKAKED FRKYLQNPGP DMVVCDEAHK LKNDDSALSK
660 670 680 690 700
CMVKILTKRR ICLTGTPLQN NLMEYHCMVN FVKPGLLGTK TEFANRFVNI
710 720 730 740 750
INRGRTKDAS PLEVSFMKRR CHVLYDHLKK CVDRKDYRVL TEAIPPKQEY
760 770 780 790 800
VINVRQTERQ CALYNAFLND IVGDSGLSKR LLPDYHMFSR IWTHPYQLVL
810 820 830 840 850
HEQRMERERV MREDAEEEAD FIDDGDGSES ESEGSFKSGS ESDSGKSVVL
860 870 880 890 900
SSDDEGSSKK KKNGNKPEIK KTAPQKKRKF LNSDDEDEED GEDTAMAILQ
910 920 930 940 950
DGIRQSKRLA GEEADLRDTD TPPEYTGWFA RLGLVKEEDR DDFALSNKLI
960 970 980 990 1000
LLVEIIKKCE EIGDKLLVFS QSLESLTLIK RMLEYMAGTG QWFADGHEAL
1010 1020 1030 1040 1050
NAEGEETWSW LEGEDYMTID GSVQSGKRDA VQTSFNDPLN LRARLMLIST
1060 1070 1080 1090 1100
RAGSLGTNMV AANRVIIFDA CWNPSHDTQS LFRVYRFGQT KPVYIYRFIA
1110 1120 1130 1140 1150
QGTMEERIYK RQVTKESTSM RVVDEAQIQR HYLGNDLTEL YQFTPSTFDP
1160 1170 1180 1190 1200
DVEISCAPPK DRLLADVIHK NQHAVVDYIE HDTLFANVED EKLTEQEMKD
1210 1220 1230 1240 1250
AWTDYEKDKS GMPVRAQYAA PPMPGFPNGM IVGQNVQALL QNRMNQGIRV
1260 1270 1280 1290 1300
DQMQHDILFK ELQKMRIKDA GTAVKIVLLR NLLEQILPYI PDEMRGGMSE
1310 1320 1330 1340 1350
FNTHFIRLVH ETDRKMETPA DLLRKSLESF KTVIKMVKMI PTCREPLARM

TRDYPYLFA
Length:1,359
Mass (Da):156,193
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEB4342547D4F4E64
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti479C → F in CCD61253 (PubMed:9851916).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF134186 mRNA Translation: AAD55361.1
FO080106 Genomic DNA Translation: CCD61253.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T34036

NCBI Reference Sequences

More...
RefSeqi
NP_001020958.1, NM_001025787.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Cel.22650

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
172077

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_B0041.7

UCSC genome browser

More...
UCSCi
B0041.7 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF134186 mRNA Translation: AAD55361.1
FO080106 Genomic DNA Translation: CCD61253.1
PIRiT34036
RefSeqiNP_001020958.1, NM_001025787.2
UniGeneiCel.22650

3D structure databases

ProteinModelPortaliQ9U7E0
SMRiQ9U7E0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.B0041.7

PTM databases

iPTMnetiQ9U7E0

Proteomic databases

EPDiQ9U7E0
PaxDbiQ9U7E0
PeptideAtlasiQ9U7E0
PRIDEiQ9U7E0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi172077
KEGGicel:CELE_B0041.7
UCSCiB0041.7 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
172077
WormBaseiB0041.7 ; CE17314 ; WBGene00006961 ; xnp-1

Phylogenomic databases

eggNOGiKOG1015 Eukaryota
COG0553 LUCA
HOGENOMiHOG000199608
InParanoidiQ9U7E0
KOiK10779
OrthoDBiEOG091G01G9
PhylomeDBiQ9U7E0

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9U7E0

Gene expression databases

BgeeiWBGene00006961 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATRX_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9U7E0
Secondary accession number(s): O02061
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: May 1, 2000
Last modified: December 5, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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