UniProtKB - Q9U3M2 (Q9U3M2_CAEEL)
Protein
Submitted name:
Ephrin RBD domain-containing protein
Gene
efn-2
Organism
Caenorhabditis elegans
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- ephrin receptor binding Source: GO_Central
GO - Biological processi
- axon guidance Source: GO_Central
- ephrin receptor signaling pathway Source: GO_Central
Enzyme and pathway databases
Reactomei | R-CEL-2682334, EPH-Ephrin signaling R-CEL-3928662, EPHB-mediated forward signaling R-CEL-3928663, EPHA-mediated growth cone collapse R-CEL-3928664, Ephrin signaling R-CEL-3928665, EPH-ephrin mediated repulsion of cells |
SignaLinki | Q9U3M2 |
Names & Taxonomyi
Protein namesi | Submitted name: Ephrin RBD domain-containing proteinImported |
Gene namesi | Name:efn-2Imported ORF Names:C43F9.8Imported, CELE_C43F9.8Imported |
Organismi | Caenorhabditis elegansImported |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | C43F9.8 ; CE35430 ; WBGene00001163 ; efn-2 |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: GO_Central
Keywords - Cellular componenti
MembraneUniRule annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5004334136 | 19 – 218 | Sequence analysisAdd BLAST | 200 |
Keywords - PTMi
Disulfide bondARBA annotation, GlycoproteinARBA annotationProteomic databases
EPDi | Q9U3M2 |
PaxDbi | Q9U3M2 |
Expressioni
Gene expression databases
Bgeei | WBGene00001163, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues |
Interactioni
GO - Molecular functioni
- ephrin receptor binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 6239.C43F9.8 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 19 – 153 | Ephrin RBDInterPro annotationAdd BLAST | 135 |
Sequence similaritiesi
Belongs to the ephrin family.PROSITE-ProRule annotation
Keywords - Domaini
SignalSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3858, Eukaryota |
GeneTreei | ENSGT00940000172385 |
HOGENOMi | CLU_084577_0_0_1 |
InParanoidi | Q9U3M2 |
OMAi | ASINIVF |
OrthoDBi | 1230708at2759 |
PhylomeDBi | Q9U3M2 |
Family and domain databases
Gene3Di | 2.60.40.420, 1 hit |
InterProi | View protein in InterPro IPR008972, Cupredoxin IPR031328, Ephrin IPR001799, Ephrin_RBD |
PANTHERi | PTHR11304, PTHR11304, 1 hit |
Pfami | View protein in Pfam PF00812, Ephrin, 1 hit |
PRINTSi | PR01347, EPHRIN |
SUPFAMi | SSF49503, SSF49503, 1 hit |
PROSITEi | View protein in PROSITE PS51551, EPHRIN_RBD_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9U3M2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQIATFILLS LFPFIGWARK IPDINWISSN PIFDVSNTDH VISVHIGDRV
60 70 80 90 100
SIRCPKSDET GKYEYSYIYM VSDEEYDHCF LSKPRLVGAC DNQTINASIN
110 120 130 140 150
IVFRSFTPTP GGFEFQPGKN YFLISTSDGT LEGIDRKKDG LCTAKQMKIK
160 170 180 190 200
FEVGQDRRGI ENPKFAARTL KKDRDAEHST PVMYVVHDES DIDDDDDGSN
210
ACSYFVSIVV LLASRYLL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX284604 Genomic DNA Translation: CAB54195.2 |
PIRi | T19914 |
RefSeqi | NP_501955.2, NM_069554.5 |
Genome annotation databases
EnsemblMetazoai | C43F9.8.1; C43F9.8.1; WBGene00001163 |
GeneIDi | 177949 |
KEGGi | cel:CELE_C43F9.8 |
UCSCi | C43F9.8, c. elegans |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX284604 Genomic DNA Translation: CAB54195.2 |
PIRi | T19914 |
RefSeqi | NP_501955.2, NM_069554.5 |
3D structure databases
SMRi | Q9U3M2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 6239.C43F9.8 |
Proteomic databases
EPDi | Q9U3M2 |
PaxDbi | Q9U3M2 |
Genome annotation databases
EnsemblMetazoai | C43F9.8.1; C43F9.8.1; WBGene00001163 |
GeneIDi | 177949 |
KEGGi | cel:CELE_C43F9.8 |
UCSCi | C43F9.8, c. elegans |
Organism-specific databases
CTDi | 177949 |
WormBasei | C43F9.8 ; CE35430 ; WBGene00001163 ; efn-2 |
Phylogenomic databases
eggNOGi | KOG3858, Eukaryota |
GeneTreei | ENSGT00940000172385 |
HOGENOMi | CLU_084577_0_0_1 |
InParanoidi | Q9U3M2 |
OMAi | ASINIVF |
OrthoDBi | 1230708at2759 |
PhylomeDBi | Q9U3M2 |
Enzyme and pathway databases
Reactomei | R-CEL-2682334, EPH-Ephrin signaling R-CEL-3928662, EPHB-mediated forward signaling R-CEL-3928663, EPHA-mediated growth cone collapse R-CEL-3928664, Ephrin signaling R-CEL-3928665, EPH-ephrin mediated repulsion of cells |
SignaLinki | Q9U3M2 |
Gene expression databases
Bgeei | WBGene00001163, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues |
Family and domain databases
Gene3Di | 2.60.40.420, 1 hit |
InterProi | View protein in InterPro IPR008972, Cupredoxin IPR031328, Ephrin IPR001799, Ephrin_RBD |
PANTHERi | PTHR11304, PTHR11304, 1 hit |
Pfami | View protein in Pfam PF00812, Ephrin, 1 hit |
PRINTSi | PR01347, EPHRIN |
SUPFAMi | SSF49503, SSF49503, 1 hit |
PROSITEi | View protein in PROSITE PS51551, EPHRIN_RBD_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9U3M2_CAEEL | |
Accessioni | Q9U3M2Primary (citable) accession number: Q9U3M2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2000 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 139 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |