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Entry version 175 (02 Jun 2021)
Sequence version 2 (01 Oct 2001)
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Protein

Nuclear RNA export factor 1

Gene

sbr

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm.

3 Publications

Miscellaneous

Mutations affect the morphogenesis of embryonic neurons, embryonic muscle and adult sensory bristles. This is thought to be due to reduced rate of protein synthesis as the mRNA is not efficiently being exported out of the nucleus.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processmRNA transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-159227, Transport of the SLBP independent Mature mRNA
R-DME-159230, Transport of the SLBP Dependant Mature mRNA
R-DME-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-DME-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nuclear RNA export factor 1
Alternative name(s):
Protein small bristles
Short name:
DmNXF1
Protein tip-associating
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sbr
Synonyms:nxf1
ORF Names:CG1664
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0003321, sbr

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002205381 – 672Nuclear RNA export factor 1Add BLAST672

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei561Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9U1H9

PRoteomics IDEntifications database

More...
PRIDEi
Q9U1H9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9U1H9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed ubiquitously.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed both maternally and zygotically. Expressed throughout embryonic development.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0003321, Expressed in female gonad and 35 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9U1H9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9U1H9, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with Nxt1 (PubMed:11780633, PubMed:31570835).

Interacts with ZC3H3 (PubMed:19364924).

Forms a complex with Nup358/RanBP2, RanGAP and Nxt1 (PubMed:14729961).

4 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
68734, 21 interactors

Database of interacting proteins

More...
DIPi
DIP-21726N

Protein interaction database and analysis system

More...
IntActi
Q9U1H9, 4 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0073267

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1672
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9U1H9

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini113 – 193RRMAdd BLAST81
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati255 – 280LRR 1Add BLAST26
Repeati281 – 304LRR 2Add BLAST24
Repeati305 – 332LRR 3Add BLAST28
Repeati333 – 360LRR 4Add BLAST28
Domaini375 – 529NTF2PROSITE-ProRule annotationAdd BLAST155
Domaini618 – 672TAP-CPROSITE-ProRule annotationAdd BLAST55

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 52DisorderedSequence analysisAdd BLAST52
Regioni73 – 101DisorderedSequence analysisAdd BLAST29
Regioni541 – 564DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi26 – 42Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi73 – 94Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi548 – 564Polar residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The leucine-rich repeats and the NTF2-domain are essential for the export of mRNA from the nucleus.
The C-terminal fragment, containing the TAP domain (also called UBA-like domain) and part of the NTF2-like domain, named the NPC-binding domain, mediates direct interactions with nucleoporin-FG-repeats and is necessary and sufficient for localization of NXF1 to the nuclear rim.
The RNA-binding domain is a non-canonical RNP-type domain.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NXF family.Curated

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3763, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007539

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011280_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9U1H9

Identification of Orthologs from Complete Genome Data

More...
OMAi
IMDCHPL

Database of Orthologous Groups

More...
OrthoDBi
1051093at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9U1H9

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00780, NTF2, 1 hit
cd14342, UBA_TAP-C, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 1 hit
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001611, Leu-rich_rpt
IPR032675, LRR_dom_sf
IPR002075, NTF2
IPR032710, NTF2-like_dom_sf
IPR018222, Nuclear_transport_factor_2_euk
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR030217, NXF_fam
IPR035979, RBD_domain_sf
IPR005637, TAP_C_dom
IPR015245, Tap_RNA-bd
IPR009060, UBA-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10662, PTHR10662, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02136, NTF2, 1 hit
PF09162, Tap-RNA_bind, 1 hit
PF03943, TAP_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00804, TAP_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46934, SSF46934, 1 hit
SSF54427, SSF54427, 1 hit
SSF54928, SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51450, LRR, 2 hits
PS50177, NTF2_DOMAIN, 1 hit
PS51281, TAP_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9U1H9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKRGGGSSQ RYNNNVGNGG GRYNAPEDFD DFDVEDRQRR KDRNKRRVSF
60 70 80 90 100
KPSQCLHNKK DIKLRPEDLR RWDEDDDMSD MTTAVKDRPT SRRRGSPIPR
110 120 130 140 150
GKFGKLMPNS FGWYQVTLQN AQIYEKETLL SALLAAMSPH VFIPQYWRVE
160 170 180 190 200
RNCVIFFTDD YEAAERIQHL GKNGHLPDGY RLMPRVRSGI PLVAIDDAFK
210 220 230 240 250
EKMKVTMAKR YNIQTKALDL SRFHADPDLK QVFCPLFRQN VMGAAIDIMC
260 270 280 290 300
DNIPDLEALN LNDNSISSME AFKGVEKRLP NLKILYLGDN KIPSLAHLVV
310 320 330 340 350
LRNLSILELV LKNNPCRSRY KDSQQFISEV RRKFPKLVKL DGETLEPQIT
360 370 380 390 400
FDLSEQGRLL ETKASYLCDV AGAEVVRQFL DQYFRIFDSG NRQALLDAYH
410 420 430 440 450
EKAMLSISMP SASQAGRLNS FWKFNRNLRR LLNGEENRTR NLKYGRLACV
460 470 480 490 500
STLDEWPKTQ HDRRTFTVDL TIYNTSMMVF TVTGLFKELN DETNNPASME
510 520 530 540 550
LYDVRHFART YVVVPQNNGF CIRNETIFIT NATHEQVREF KRSQHQPAPG
560 570 580 590 600
AMPSTSSAVT SPQAGAAAGL QGRLNALGVA TGPVAILSGD PLAATAPVNS
610 620 630 640 650
GSAAISTTAV APGAQDESTK MQMIEAMSAQ SQMNVIWSRK CLEETNWDFN
660 670
HAAFVFEKLF KENKIPPEAF MK
Length:672
Mass (Da):76,249
Last modified:October 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFADEF8B6DA7B7F5F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A4D6K0P9A0A4D6K0P9_DROME
Small bristles, isoform B
sbr CG17335, CT4634, Dm nxf1, Dmel\CG1664, DmNXF1
536Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAL39560 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAB75848 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti292I → V in CAB75848 (PubMed:11779805).Curated1
Sequence conflicti640K → KR in CAB75849 (PubMed:11779805).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ251947 mRNA Translation: CAB64382.2
AJ272389 Genomic DNA Translation: CAB75848.1 Different initiation.
AJ272390 Genomic DNA Translation: CAB75849.1 Sequence problems.
AJ318090 mRNA Translation: CAC41645.1
AE014298 Genomic DNA Translation: AAF47959.3
AY069415 mRNA Translation: AAL39560.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_524660.1, NM_079921.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0073411; FBpp0073267; FBgn0003321

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
43944

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG1664

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ251947 mRNA Translation: CAB64382.2
AJ272389 Genomic DNA Translation: CAB75848.1 Different initiation.
AJ272390 Genomic DNA Translation: CAB75849.1 Sequence problems.
AJ318090 mRNA Translation: CAC41645.1
AE014298 Genomic DNA Translation: AAF47959.3
AY069415 mRNA Translation: AAL39560.1 Different initiation.
RefSeqiNP_524660.1, NM_079921.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6IHJX-ray2.70A/C359-544[»]
SMRiQ9U1H9
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi68734, 21 interactors
DIPiDIP-21726N
IntActiQ9U1H9, 4 interactors
STRINGi7227.FBpp0073267

PTM databases

iPTMnetiQ9U1H9

Proteomic databases

PaxDbiQ9U1H9
PRIDEiQ9U1H9

Genome annotation databases

EnsemblMetazoaiFBtr0073411; FBpp0073267; FBgn0003321
GeneIDi43944
KEGGidme:Dmel_CG1664

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
43944
FlyBaseiFBgn0003321, sbr

Phylogenomic databases

eggNOGiKOG3763, Eukaryota
GeneTreeiENSGT00390000007539
HOGENOMiCLU_011280_1_1_1
InParanoidiQ9U1H9
OMAiIMDCHPL
OrthoDBi1051093at2759
PhylomeDBiQ9U1H9

Enzyme and pathway databases

ReactomeiR-DME-159227, Transport of the SLBP independent Mature mRNA
R-DME-159230, Transport of the SLBP Dependant Mature mRNA
R-DME-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-DME-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
43944, 1 hit in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
43944

Protein Ontology

More...
PROi
PR:Q9U1H9

Gene expression databases

BgeeiFBgn0003321, Expressed in female gonad and 35 other tissues
ExpressionAtlasiQ9U1H9, baseline and differential
GenevisibleiQ9U1H9, DM

Family and domain databases

CDDicd00780, NTF2, 1 hit
cd14342, UBA_TAP-C, 1 hit
Gene3Di3.30.70.330, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR001611, Leu-rich_rpt
IPR032675, LRR_dom_sf
IPR002075, NTF2
IPR032710, NTF2-like_dom_sf
IPR018222, Nuclear_transport_factor_2_euk
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR030217, NXF_fam
IPR035979, RBD_domain_sf
IPR005637, TAP_C_dom
IPR015245, Tap_RNA-bd
IPR009060, UBA-like_sf
PANTHERiPTHR10662, PTHR10662, 1 hit
PfamiView protein in Pfam
PF02136, NTF2, 1 hit
PF09162, Tap-RNA_bind, 1 hit
PF03943, TAP_C, 1 hit
SMARTiView protein in SMART
SM00804, TAP_C, 1 hit
SUPFAMiSSF46934, SSF46934, 1 hit
SSF54427, SSF54427, 1 hit
SSF54928, SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS51450, LRR, 2 hits
PS50177, NTF2_DOMAIN, 1 hit
PS51281, TAP_C, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNXF1_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9U1H9
Secondary accession number(s): Q9NFQ2
, Q9NFQ3, Q9VZ65, Q9VZ68
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2002
Last sequence update: October 1, 2001
Last modified: June 2, 2021
This is version 175 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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